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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Gp78 deficiency in hepatocytes alleviates hepatic ischemia-reperfusion injury via suppressing ACSL4-mediated ferroptosis
Changbiao Li, Yichao Wu, Kangchen Chen, Ronggao Chen, Shengjun Xu, Beng Yang, Zhengxing Lian, Xiaodong Wang, Kai Wang, Haiyang Xie, Shusen Zheng, Zhikun Liu, Di Wang, Xiao Xu
Cell Death Dis. 2023 Dec; 14(12): 810. Published online 2023 Dec 8. doi: 10.1038/s41419-023-06294-x
PMCID:
PMC10709349
AbstractArticlePDF–5.8M
3.
Ubiquitination of NLRP3 by gp78/Insig-1 restrains NLRP3 inflammasome activation
Ting Xu, Weiwei Yu, Hui Fang, Zhen Wang, Zhexu Chi, Xingchen Guo, Danlu Jiang, Kailian Zhang, Sheng Chen, Mobai Li, Yuxian Guo, Jian Zhang, Dehang Yang, Qianzhou Yu, Di Wang, Xue Zhang
Cell Death Differ. 2022 Aug; 29(8): 1582–1595. Published online 2022 Feb 2. doi: 10.1038/s41418-022-00947-8
PMCID:
PMC9345978
AbstractArticlePDF–3.6M
4.
AMFR drives allergic asthma development by promoting alveolar macrophage–derived GM-CSF production
Huihui Zhang, Ran Wei, Xinyi Yang, Lu Xu, Hongchao Jiang, Mengkai Li, Haixia Jiang, Haibo Zhang, Zhihong Chen, Feng Qian, Lei Sun
J Exp Med. 2022 May 2; 219(5): e20211828. Published online 2022 Mar 25. doi: 10.1084/jem.20211828
PMCID:
PMC8961293
AbstractArticlePDF–9.2M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
7.
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling
Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler
Science. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812
PMCID:
PMC7206793
AbstractArticlePDF–2.2M
8.
Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2
Zhang-Sen Zhou, Mei-Xin Li, Jie Liu, Hengwu Jiao, Jing-Ming Xia, Xiong-Jie Shi, Huabin Zhao, Liping Chu, Jingrong Liu, Wei Qi, Jie Luo, Bao-Liang Song
Nat Commun. 2020; 11: 379. Published online 2020 Jan 17. doi: 10.1038/s41467-019-14231-w
PMCID:
PMC6969111
AbstractArticlePDF–2.3M
9.
Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance
Doyoung Kwon, Sung-Mi Kim, Peyton Jacob, Yi Liu, III, Maria Almira Correia
Mol Pharmacol. 2019 Nov; 96(5): 641–654. Published online 2019 Nov. doi: 10.1124/mol.119.117069
PMCID:
PMC6790065
AbstractArticlePDF–1.8M
10.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
11.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
12.
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1
Sam A Menzies, Norbert Volkmar, Dick JH van den Boomen, Richard T Timms, Anna S Dickson, James A Nathan, Paul J Lehner
eLife. 2018; 7: e40009. Published online 2018 Dec 13. doi: 10.7554/eLife.40009
PMCID:
PMC6292692
AbstractArticlePDF–5.8M
13.
Role of glycoprotein 78 and cidec in hepatic steatosis
Jie Li, Guocai Liu, Feng Zhang, Zhiwen Zhang, Yuqiao Xu, Qing Li
Mol Med Rep. 2017 Aug; 16(2): 1871–1877. Published online 2017 Jun 21. doi: 10.3892/mmr.2017.6834
PMCID:
PMC5561988
AbstractArticlePDF–1.2M
14.
Cholesterol and fatty acids regulate cysteine ubiquitination of ACAT2 through competitive oxidation
Yong-Jian Wang, Yan Bian, Jie Luo, Ming Lu, Ying Xiong, Shu-Yuan Guo, Hui-Yong Yin, Xu Lin, Qin Li, Catherine CY Chang, Ta-Yuan Chang, Bo-Liang Li, Bao-Liang Song
Nat Cell Biol. Author manuscript; available in PMC 2017 Dec 12.
Published in final edited form as: Nat Cell Biol. 2017 Jul; 19(7): 808–819. Published online 2017 Jun 12. doi: 10.1038/ncb3551
Correction in:
Nat Cell Biol. 2017 Nov 29; 19(12): 1441.
PMCID:
PMC5518634
AbstractArticlePDF–1.3M
15.
A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)
Stefan H. Geyer, Lukas Reissig, Julia Rose, Robert Wilson, Fabrice Prin, Dorota Szumska, Ramiro Ramirez‐Solis, Catherine Tudor, Jacqui White, Timothy J. Mohun, Wolfgang J. Weninger
J Anat. 2017 May; 230(5): 710–719. Published online 2017 Feb 9. doi: 10.1111/joa.12590
PMCID:
PMC5382591
AbstractArticlePDF–1.5M
16.
BOK Is a Non-Canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
Fabien Llambi, Yue-Ming Wang, Bernadette Victor, Mao Yang, Desiree M. Schneider, Sébastien Gingras, Melissa J. Parsons, Janet H. Zheng, Scott A. Brown, Stéphane Pelletier, Tudor Moldoveanu, Taosheng Chen, Douglas R. Green
Cell. Author manuscript; available in PMC 2017 Apr 7.
Published in final edited form as: Cell. 2016 Apr 7; 165(2): 421–433. Published online 2016 Mar 3. doi: 10.1016/j.cell.2016.02.026
PMCID:
PMC5018360
AbstractArticlePDF–1.6M
17.
Gp78, an E3 Ubiquitin Ligase Acts as a Gatekeeper Suppressing Nonalcoholic Steatohepatitis (NASH) and Liver Cancer
Tianpeng Zhang, Dhong Hyo Kho, Ying Wang, Yosuke Harazono, Kosei Nakajima, Youming Xie, Avraham Raz
PLoS One. 2015; 10(3): e0118448. Published online 2015 Mar 19. doi: 10.1371/journal.pone.0118448
PMCID:
PMC4366401
AbstractArticlePDF–3.7M
18.
Ubiquitin Ligase gp78 Targets Unglycosylated Prion Protein PrP for Ubiquitylation and Degradation
Jia Shao, Vitnary Choe, Haili Cheng, Yien Che Tsai, Allan M. Weissman, Shiwen Luo, Hai Rao
PLoS One. 2014; 9(4): e92290. Published online 2014 Apr 8. doi: 10.1371/journal.pone.0092290
PMCID:
PMC3979651
AbstractArticlePDF–1.6M
19.
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins
Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins
Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110
PMCID:
PMC3581954
AbstractArticlePDF–2.3M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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