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Items: 1 to 20 of 24

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease
Robyn Laura Kosinsky, Maria Zerche, Ana Patricia Kutschat, Asha Nair, Zhenqing Ye, Dominik Saul, Maximilian von Heesen, Jessica J. Friton, Ana Carolina Schwarzer, Nadia Paglilla, Shehzad Z. Sheikh, Florian Wegwitz, Zhifu Sun, Michael Ghadimi, Rodney D. Newberry, R. Balfour Sartor, William A. Faubion, Steven A. Johnsen
Cell Death Differ. 2021 Nov; 28(11): 3161–3175. Published online 2021 Jun 4. doi: 10.1038/s41418-021-00808-w
PMCID:
PMC8563960
AbstractArticlePDF–6.1M
3.
Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation
Nathan J. VanDusen, Julianna Y. Lee, Weiliang Gu, Catalina E. Butler, Isha Sethi, Yanjiang Zheng, Justin S. King, Pingzhu Zhou, Shengbao Suo, Yuxuan Guo, Qing Ma, Guo-Cheng Yuan, William T. Pu
Nat Commun. 2021; 12: 4442. Published online 2021 Jul 21. doi: 10.1038/s41467-021-24743-z
Correction in:
Nat Commun. 2021; 12: 5105.
PMCID:
PMC8295283
AbstractArticlePDF–5.1M
4.
USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response
Evangelos Prokakis, Anna Dyas, Regina Grün, Sonja Fritzsche, Upasana Bedi, Zahra B. Kazerouni, Robyn L. Kosinsky, Steven A. Johnsen, Florian Wegwitz
Oncogene. 2021; 40(23): 4004–4018. Published online 2021 May 18. doi: 10.1038/s41388-021-01814-5
PMCID:
PMC8195738
AbstractArticlePDF–5.0M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk
Zeynab Najafova, Peng Liu, Florian Wegwitz, Mubashir Ahmad, Liezel Tamon, Robyn Laura Kosinsky, Wanhua Xie, Steven A. Johnsen, Jan Tuckermann
Cell Death Differ. 2021 Feb; 28(2): 700–714. Published online 2020 Sep 8. doi: 10.1038/s41418-020-00614-w
PMCID:
PMC7862367
AbstractArticlePDF–3.6M
7.
Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination
Hannah M Wüst, Amélie Wegener, Franziska Fröb, Anna C Hartwig, Florian Wegwitz, Vijayalakshmi Kari, Margit Schimmel, Ernst R Tamm, Steven A Johnsen, Michael Wegner, Elisabeth Sock
Nucleic Acids Res. 2020 Sep 18; 48(16): 8959–8976. Published online 2020 Jul 16. doi: 10.1093/nar/gkaa606
PMCID:
PMC7498331
AbstractArticlePDF–28M
8.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
9.
LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function
Alexa K. Wade, Yanping Liu, Maigen M. Bethea, Eliana Toren, Hubert M. Tse, Chad S. Hunter
J Biol Chem. 2019 Aug 2; 294(31): 11728–11740. Published online 2019 Jun 11. doi: 10.1074/jbc.RA118.006985
PMCID:
PMC6682733
AbstractArticlePDF–3.1M
10.
Loss of RNF40 Decreases NF-κB Activity in Colorectal Cancer Cells and Reduces Colitis Burden in Mice
Robyn Laura Kosinsky, Robert Lorenz Chua, Martin Qui, Dominik Saul, Dawid Mehlich, Philipp Ströbel, Hans-Ulrich Schildhaus, Florian Wegwitz, William A Faubion, Steven A Johnsen
J Crohns Colitis. 2019 Mar; 13(3): 362–373. Published online 2018 Oct 13. doi: 10.1093/ecco-jcc/jjy165
PMCID:
PMC6599279
AbstractArticlePDF–5.6M
11.
E3 Ubiquitin Ligases RNF20 and RNF40 Are Required for Double-Stranded Break (DSB) Repair: Evidence for Monoubiquitination of Histone H2B Lysine 120 as a Novel Axis of DSB Signaling and Repair
Clare C. So, Shaliny Ramachandran, Alberto Martin
Mol Cell Biol. 2019 Apr 15; 39(8): e00488-18. Prepublished online 2019 Jan 28. Published online 2019 Apr 2. doi: 10.1128/MCB.00488-18
PMCID:
PMC6447412
AbstractArticlePDF–5.0M
12.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
13.
RNF40 regulates gene expression in an epigenetic context-dependent manner
Wanhua Xie, Sankari Nagarajan, Simon J. Baumgart, Robyn Laura Kosinsky, Zeynab Najafova, Vijayalakshmi Kari, Magali Hennion, Daniela Indenbirken, Stefan Bonn, Adam Grundhoff, Florian Wegwitz, Ahmed Mansouri, Steven A. Johnsen
Genome Biol. 2017; 18: 32. Published online 2017 Feb 16. doi: 10.1186/s13059-017-1159-5
PMCID:
PMC5314486
AbstractArticlePDF–6.1M
14.
Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability
Sophia B. Chernikova, Olga V. Razorenova, John P. Higgins, Brock J. Sishc, Monica Nicolau, Jennifer A. Dorth, Diana A. Chernikova, Shirley Kwok, James D. Brooks, Susan M. Bailey, John C. Game, J. Martin Brown
Cancer Res. Author manuscript; available in PMC 2013 Apr 15.
Published in final edited form as: Cancer Res. 2012 Apr 15; 72(8): 2111–2119. Published online 2012 Feb 21. doi: 10.1158/0008-5472.CAN-11-2209
PMCID:
PMC3328627
AbstractArticlePDF–5.0M
15.
Dynamic Loss of H2B Ubiquitylation without Corresponding Changes in H3K4 Trimethylation during Myogenic Differentiation
Vasupradha Vethantham, Yan Yang, Christopher Bowman, Patrik Asp, Jeong-Heon Lee, David G. Skalnik, Brian D. Dynlacht
Mol Cell Biol. 2012 Mar; 32(6): 1044–1055. doi: 10.1128/MCB.06026-11
PMCID:
PMC3295016
AbstractArticlePDF–2.3M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Deficiency in Bre1 Impairs Homologous Recombination Repair and Cell Cycle Checkpoint Response to Radiation Damage in Mammalian Cells
Sophia B. Chernikova, Jennifer A. Dorth, Olga V. Razorenova, John C. Game, J. Martin Brown
Radiat Res. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: Radiat Res. 2010 Nov; 174(5): 558–565. Published online 2010 Aug 25. doi: 10.1667/RR2184.1
PMCID:
PMC2988074
AbstractArticlePDF–755K
18.
CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3′-end processing
Judith Pirngruber, Andrei Shchebet, Lisa Schreiber, Efrat Shema, Neri Minsky, Rob D Chapman, Dirk Eick, Yael Aylon, Moshe Oren, Steven A Johnsen
EMBO Rep. 2009 Aug; 10(8): 894–900. Published online 2009 Jul 3. doi: 10.1038/embor.2009.108
PMCID:
PMC2726677
AbstractArticlePDF–609K
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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