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Select item 113700361.

MiR-100-5p-rich small extracellular vesicles from activated neuron to aggravate microglial activation and neuronal activity after stroke

Danqing Xin, Tingting Li, Yijing Zhao, Xiaofan Guo, Chengcheng Gai, Zige Jiang, Shuwen Yu, Jiao Cheng, Yan Song, Yahong Cheng, Qian Luo, Bing Gu, Dexiang Liu, Zhen Wang

J Nanobiotechnology. 2024; 22: 534. Published online 2024 Sep 3. doi: 10.1186/s12951-024-02782-0

PMCID:: PMC11370036

Abstract Article PDF–16M

Select item 110341062.

Macrophage-derived mir-100-5p orchestrates synovial proliferation and inflammation in rheumatoid arthritis through mTOR signaling

Huan Liu, Yuehong Chen, Yupeng Huang, Ling Wei, Jingjing Ran, Qianwei Li, Yunru Tian, Zhongling Luo, Leiyi Yang, Hongjiang Liu, Geng Yin, Qibing Xie

J Nanobiotechnology. 2024; 22: 197. Published online 2024 Apr 22. doi: 10.1186/s12951-024-02444-1

PMCID:: PMC11034106

Abstract Article PDF–14M

Select item 109547333.

Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis

Guo Chen, Xinyuan Li, Xiang Zhou, Yang Li, Haitao Yu, Xiang Peng, Xuesong Bai, Chunlin Zhang, Zhenwei Feng, Yuhua Mei, Li Li, Yu Liu, Xin Gou, Yuanbin Jiang

Sci Rep. 2024; 14: 6720. Published online 2024 Mar 20. doi: 10.1038/s41598-024-56950-1

PMCID:: PMC10954733

Abstract Article PDF–5.2M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105949135.

miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson’s disease model via regulation of Nox4/ROS/Nrf2 signaling

Songzhe He, Qiongqiong Wang, Liankuai Chen, Yusheng Jason He, Xiaofang Wang, Shaogang Qu

J Transl Med. 2023; 21: 747. Published online 2023 Oct 24. doi: 10.1186/s12967-023-04638-x

PMCID:: PMC10594913

Abstract Article PDF–18M

Select item 104970036.

miR-100-5p activation of the autophagy response through inhibiting the mTOR pathway and suppression of cerebral infarction progression in mice

Xiaoyun Cao, Xiangjian Zhang, Junmin Chen, Qian Sun, Yufan Sun, Na Lin, Xiaoxia Liu

Aging (Albany NY) 2023 Aug 30; 15(16): 8315–8324. Published online 2023 Aug 22. doi: 10.18632/aging.204971

PMCID:: PMC10497003

Abstract Article PDF–894K

Select item 91531407.

Mechanosensitive miR‐100 coordinates TGFβ and Wnt signaling in osteocytes during fluid shear stress

Neha S. Dole, Jihee Yoon, David A. Monteiro, Jason Yang, Courtney M. Mazur, Serra Kaya, Cassandra D. Belair, Tamara Alliston

FASEB J. 2021 Oct; 35(10): e21883. Published online 2021 Sep 27. doi: 10.1096/fj.202100930

PMCID:: PMC9153140

Abstract Article PDF–1.3M

Select item 89742018.

Inhibition of miRNA-100 facilitates bone regeneration defects of mesenchymal stem cells in osteoporotic mice through the protein kinase B pathway

Zhengqiu Dai, Guoqiang Wei

Bioengineered. 2022; 13(1): 963–973. Published online 2022 Feb 8. doi: 10.1080/21655979.2021.2015880

PMCID:: PMC8974201

Abstract Article PDF–2.4M

Select item 86269289.

MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration

Thomas Wallach, Zoé J. Mossmann, Michal Szczepek, Max Wetzel, Rui Machado, Martin Raden, Milad Miladi, Gunnar Kleinau, Christina Krüger, Paul Dembny, Drew Adler, Yuanyuan Zhai, Victor Kumbol, Omar Dzaye, Jutta Schüler, Matthias Futschik, Rolf Backofen, Patrick Scheerer, Seija Lehnardt

Mol Neurodegener. 2021; 16: 80. Published online 2021 Nov 27. doi: 10.1186/s13024-021-00498-5

PMCID:: PMC8626928

Abstract Article PDF–4.9M

Select item 842276410.

MiR-100 overexpression attenuates high fat diet induced weight gain, liver steatosis, hypertriglyceridemia and development of metabolic syndrome in mice

Christian Smolka, Delia Schlösser, Catherine Hohnloser, Xavier Bemtgen, Caterina Jänich, Laura Schneider, Julien Martin, Dietmar Pfeifer, Martin Moser, Peter Hasselblatt, Christoph Bode, Sebastian Grundmann, Franziska Pankratz

Mol Med. 2021; 27: 101. Published online 2021 Sep 6. doi: 10.1186/s10020-021-00364-6

PMCID:: PMC8422764

Abstract Article PDF–1.9M

Select item 780214211.

Neural progenitor cell-derived nanovesicles promote hair follicle growth via miR-100

Lei Cao, Tian Tian, Yuanbo Huang, Shiqin Tao, Xiaohong Zhu, Mifang Yang, Jing Gu, Guangdong Feng, Yinni Ma, Rushan Xia, Wenrong Xu, Lei Wang

J Nanobiotechnology. 2021; 19: 20. Published online 2021 Jan 11. doi: 10.1186/s12951-020-00757-5

PMCID:: PMC7802142

Abstract Article PDF–6.2M

Select item 660673712.

Generation and Validation of miR-100 Hepatocyte-Specific Knock-Out Mice

Dong Yang, Sai Tang, Yan Yang, Fan Yang, Wengang Jiang, Yakun Liu, Fengyun Zhang, Haoshu Fang, Siying Wang, Yuxia Zhang

Front Oncol. 2019; 9: 535. Published online 2019 Jun 26. doi: 10.3389/fonc.2019.00535

PMCID:: PMC6606737

Abstract Article PDF–2.9M

Select item 518212413.

MicroRNA-101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks

Giordano Lippi, Catarina C. Fernandes, Laura A. Ewell, Danielle John, Benedetto Romoli, Giulia Curia, Seth R. Taylor, E. Paxon Frady, Anne B. Jensen, Jerry C. Liu, Melanie M. Chaabane, Cherine Belal, Jason L. Nathanson, Michele Zoli, Jill K. Leutgeb, Giuseppe Biagini, Gene W. Yeo, Darwin K. Berg

Neuron. Author manuscript; available in PMC 2017 Dec 21.

Published in final edited form as: Neuron. 2016 Dec 21; 92(6): 1337–1351. Published online 2016 Dec 8. doi: 10.1016/j.neuron.2016.11.017

PMCID:: PMC5182124

Abstract Article PDF–3.2M

Select item 450312614.

Downregulation of microRNA-100 protects H₂O₂-induced apoptosis in neonatal cardiomyocytes

An Chen, Gonghui Li, Linlin Chen, Jingbin Guo, Yingfeng Liu

Int J Clin Exp Pathol. 2015; 8(5): 5491–5496. Published online 2015 May 1.

PMCID:: PMC4503126

Abstract Article PDF–640K

Select item 440338015.

miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement

Qin-Hua Gu, Danni Yu, Zhonghua Hu, Xing Liu, Yanqin Yang, Yan Luo, Jun Zhu, Zheng Li

Nat Commun. 2015 Apr 10; 6: 6789. Published online 2015 Apr 10. doi: 10.1038/ncomms7789

PMCID:: PMC4403380

Abstract Article PDF–4.4M

Select item 426490816.

MicroRNA-100-5p indirectly modulates the expression of Il6, Ptgs1/2 and Tlr4 mRNA in the mouse follicular dendritic cell-like cell line, FL-Y

Susan R Aungier, Hitoshi Ohmori, Michael Clinton, Neil A Mabbott

Immunology. 2015 Jan; 144(1): 34–44. Published online 2014 Dec 8. doi: 10.1111/imm.12342

PMCID:: PMC4264908

Abstract Article PDF–635K

Select item 424632117.

K-Ras^V14I recapitulates Noonan syndrome in mice

Isabel Hernández-Porras, Salvatore Fabbiano, Alberto J. Schuhmacher, Alexandra Aicher, Marta Cañamero, Juan Antonio Cámara, Lorena Cussó, Manuel Desco, Christopher Heeschen, Francisca Mulero, Xosé R. Bustelo, Carmen Guerra, Mariano Barbacid

Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46): 16395–16400. Published online 2014 Oct 30. doi: 10.1073/pnas.1418126111

PMCID:: PMC4246321

Abstract Article PDF–1.0M

Select item 366579818.

MicroRNA-99 Family Targets AKT/mTOR Signaling Pathway in Dermal Wound Healing

Yi Jin, Stéphanie D. Tymen, Dan Chen, Zong Juan Fang, Yan Zhao, Dragan Dragas, Yang Dai, Phillip T. Marucha, Xiaofeng Zhou

PLoS One. 2013; 8(5): e64434. Published online 2013 May 28. doi: 10.1371/journal.pone.0064434

PMCID:: PMC3665798

Abstract Article PDF–1.2M

Select item 364003219.

Identifying MicroRNAs Involved in Degeneration of the Organ of Corti during Age-Related Hearing Loss

Qian Zhang, Huizhan Liu, JoAnn McGee, Edward J. Walsh, Garrett A. Soukup, David Z. Z. He

PLoS One. 2013; 8(4): e62786. Published online 2013 Apr 30. doi: 10.1371/journal.pone.0062786

PMCID:: PMC3640032

Abstract Article PDF–2.2M

Select item 335454920.

Apoptosis of Limb Innervating Motor Neurons and Erosion of Motor Pool Identity Upon Lineage Specific Dicer Inactivation

Jun-An Chen, Hynek Wichterle

Front Neurosci. 2012; 6: 69. Published online 2012 May 17. doi: 10.3389/fnins.2012.00069

PMCID:: PMC3354549

Abstract Article PDF–4.7M

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