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Items: 1 to 20 of 44

1.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
2.
Comprehensive analysis regarding the prognostic significance of downregulated ferroptosis-related gene AKR1C2 in gastric cancer and its underlying roles in immune response
Wei Liu, Fan Zhang, Keda Yang, Yuanliang Yan
PLoS One. 2023; 18(1): e0280989. Published online 2023 Jan 26. doi: 10.1371/journal.pone.0280989
PMCID:
PMC9879425
AbstractArticlePDF–2.8M
3.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
4.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
5.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
6.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
7.
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway
Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan
J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5
PMCID:
PMC9102726
AbstractArticlePDF–15M
8.
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord
Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6
PMCID:
PMC8760077
AbstractArticlePDF–12M
9.
Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation
Nisan Denizce Can, Ezgi Basturk, Tugba Kizilboga, Izzet Mehmet Akcay, Baran Dingiloglu, Ozge Tatli, Sevilay Acar, Pelin Ozfiliz Kilbas, Efe Elbeyli, Serena Muratcioglu, Ayse Tarbin Jannuzzi, Attila Gursoy, Ozlem Keskin, Hamdi Levent Doganay, Betul Karademir Yilmaz, Gizem Dinler Doganay
PLoS One. 2021; 16(8): e0256640. Published online 2021 Aug 24. doi: 10.1371/journal.pone.0256640
PMCID:
PMC8384158
AbstractArticlePDF–3.7M
10.
Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb‐202 in gastric cancer
Hitomi Sakai, Hisato Kawakami, Takeshi Teramura, Yuta Onodera, Elizabeth Somers, Keiji Furuuchi, Toshimitsu Uenaka, Ryoji Kato, Kazuhiko Nakagawa
Clin Transl Med. 2021 Jun; 11(6): e454. Published online 2021 Jun 1. doi: 10.1002/ctm2.454
PMCID:
PMC8167866
AbstractArticlePDF–7.0M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
12.
AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants
Giada Ostinelli, Jinchu Vijay, Marie-Claude Vohl, Elin Grundberg, Andre Tchernof
Mol Cell Endocrinol. 2021 May 1; 527: 111220. doi: 10.1016/j.mce.2021.111220
PMCID:
PMC8052191
AbstractArticlePDF–3.3M
13.
AEG-1 Promotes Metastasis Through Downstream AKR1C2 and NF1 in Liver Cancer
Cong Li, Xia Wu, Wei Zhang, Jia Li, Huawei Liu, Ming Hao, Junsong Wang, Honghai Zhang, Gengxia Yang, Meijun Hao, Shoupeng Sheng, Yu Sun, Jiang Long, Xiongbing Hu, Hanshuo Zhang, Caixia Hu, Li Li, Jiasheng Zheng
Oncol Res. 2015; 22(4): 203–211. Published online 2015 Sep 15. doi: 10.3727/096504015X14386062091352
PMCID:
PMC7838427
AbstractArticlePDF–12M
14.
ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells
Jaya Bhushan, Joshua B. Radke, Yi-Chieh Perng, Michael Mcallaster, Deborah J. Lenschow, Herbert W. Virgin, L. David Sibley
mBio. 2020 Sep-Oct; 11(5): e00852-20. Published online 2020 Oct 6. doi: 10.1128/mBio.00852-20
PMCID:
PMC7542356
AbstractArticlePDF–2.4M
15.
Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani
Oncogene. Author manuscript; available in PMC 2020 Sep 29.
Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9
PMCID:
PMC7523706
AbstractArticlePDF–2.3M
16.
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway
Zhan‐Fei Zhang, Tie‐Jun Huang, Xin‐Ke Zhang, Yu‐Jie Xie, Si‐Ting Lin, Fei‐Fei Luo, Dong‐Fang Meng, Hao Hu, Jing Wang, Li‐Xia Peng, Chao‐Nan Qian, Chao Cheng, Bi‐Jun Huang
J Cell Mol Med. 2020 Sep; 24(17): 9999–10012. Published online 2020 Jul 17. doi: 10.1111/jcmm.15604
PMCID:
PMC7520259
AbstractArticlePDF–2.5M
17.
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak
Mol Cell. Author manuscript; available in PMC 2021 Jun 18.
Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027
PMCID:
PMC7306005
AbstractArticlePDF–3.2M
18.
Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis
Mara Gagliardi, Diego Cotella, Claudio Santoro, Davide Corà, Nickolai A. Barlev, Mauro Piacentini, Marco Corazzari
Cell Death Dis. 2019 Dec; 10(12): 902. Published online 2019 Nov 28. doi: 10.1038/s41419-019-2143-7
PMCID:
PMC6883066
AbstractArticlePDF–1.2M
19.
DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169
Vijay R. Menon, Varsha Ananthapadmanabhan, Selene Swanson, Siddharth Saini, Fatmata Sesay, Vasily Yakovlev, Laurence Florens, James A. DeCaprio, Michael P. Washburn, Mikhail Dozmorov, Larisa Litovchick
Cell Cycle. 2019; 18(5): 531–551. Published online 2019 Feb 17. doi: 10.1080/15384101.2019.1577525
PMCID:
PMC6464593
AbstractArticlePDF–2.8M
20.
Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation
Gergő Horváth, Orsolya Egyed, Changguo Tang, Mihály Kovács, András Micsonai, József Kardos, Orsolya Toke
Sci Rep. 2019; 9: 4825. Published online 2019 Mar 18. doi: 10.1038/s41598-019-41180-7
PMCID:
PMC6423008
AbstractArticlePDF–6.2M

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