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Items: 1 to 20 of 30

1.
TKTL1 Knockdown Impairs Hypoxia-Induced Glucose-6-phosphate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase Overexpression
Inês Baptista, Effrosyni Karakitsou, Jean-Baptiste Cazier, Ulrich L. Günther, Silvia Marin, Marta Cascante
Int J Mol Sci. 2022 Apr; 23(7): 3574. Published online 2022 Mar 25. doi: 10.3390/ijms23073574
PMCID:
PMC8999113
AbstractArticlePDF–2.9M
2.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
High TKTL1 expression as a sign of poor prognosis in colorectal cancer with synchronous rather than metachronous liver metastases
Reetta Peltonen, Kaisa Ahopelto, Jaana Hagström, Camilla Böckelman, Caj Haglund, Helena Isoniemi
Cancer Biol Ther. 2020; 21(9): 826–831. Published online 2020 Aug 14. doi: 10.1080/15384047.2020.1803008
PMCID:
PMC7515493
AbstractArticlePDF–1.3M
5.
Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma
S. Saman, M.J. Stagno, S.W. Warmann, N.P. Malek, R.R. Plentz, E. Schmid
Cancer Biomark. 2020; 27(1): 129–137. Prepublished online 2019 Nov 15. Published online 2019 Dec 30. doi: 10.3233/CBM-190414
PMCID:
PMC7029314
AbstractArticlePDF–578K
6.
The human transketolase-like proteins TKTL1 and TKTL2 are bona fide transketolases
Gaurang P. Deshpande, Hugh-George Patterton, M. Faadiel Essop
BMC Struct Biol. 2019; 19: 2. Published online 2019 Jan 15. doi: 10.1186/s12900-018-0099-y
PMCID:
PMC6334435
AbstractArticlePDF–3.7M
7.
Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation
Sonja Heller, Gabriele D. Maurer, Christina Wanka, Ute Hofmann, Anna-Luisa Luger, Ines Bruns, Joachim P. Steinbach, Johannes Rieger
Int J Mol Sci. 2018 Aug; 19(8): 2168. Published online 2018 Jul 25. doi: 10.3390/ijms19082168
PMCID:
PMC6121283
AbstractArticlePDF–3.3M
8.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
9.
Transketolase-like protein 1 expression predicts poor prognosis in colorectal cancer
Kaisa Ahopelto, Camilla Böckelman, Jaana Hagström, Selja Koskensalo, Caj Haglund
Cancer Biol Ther. 2016 Feb; 17(2): 163–168. Published online 2015 Dec 9. doi: 10.1080/15384047.2015.1121347
PMCID:
PMC4847984
AbstractArticlePDF–503K
10.
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells
Aparna Jayachandran, Pu-Han Lo, Anderly C. Chueh, Prashanth Prithviraj, Ramyar Molania, Mercedes Davalos-Salas, Matthew Anaka, Marzena Walkiewicz, Jonathan Cebon, Andreas Behren
BMC Cancer. 2016; 16: 134. Published online 2016 Feb 22. doi: 10.1186/s12885-016-2185-5
PMCID:
PMC4763451
AbstractArticlePDF–2.2M
11.
TKTL1 expression in human malign and benign cell lines
Ulrike Kämmerer, Olivier Gires, Nadja Pfetzer, Armin Wiegering, Rainer Johannes Klement, Christoph Otto
BMC Cancer. 2015; 15: 2. Published online 2015 Jun 10. doi: 10.1186/1471-2407-15-2
PMCID:
PMC4506423
AbstractArticlePDF–1.0M
12.
A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells
Martin Grimm, Steffen Schmitt, Peter Teriete, Thorsten Biegner, Arnulf Stenzl, Jörg Hennenlotter, Hans-Joachim Muhs, Adelheid Munz, Tatjana Nadtotschi, Klemens König, Jörg Sänger, Oliver Feyen, Heiko Hofmann, Siegmar Reinert, Johannes F Coy
BMC Cancer. 2013; 13: 569. Published online 2013 Dec 4. doi: 10.1186/1471-2407-13-569
PMCID:
PMC4235042
AbstractArticlePDF–3.3M
13.
Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network
Zhao Chen, Hua Tang, Rehan Qayyum, Ursula M. Schick, Michael A. Nalls, Robert Handsaker, Jin Li, Yingchang Lu, Lisa R. Yanek, Brendan Keating, Yan Meng, Frank J.A. van Rooij, Yukinori Okada, Michiaki Kubo, Laura Rasmussen-Torvik, Margaux F. Keller, Leslie Lange, Michele Evans, Erwin P. Bottinger, Michael D. Linderman, Douglas M. Ruderfer, Hakon Hakonarson, George Papanicolaou, Alan B. Zonderman, Omri Gottesman, BioBank Japan Project, CHARGE Consortium, Cynthia Thomson, Elad Ziv, Andrew B. Singleton, Ruth J.F. Loos, Patrick M.A. Sleiman, Santhi Ganesh, Steven McCarroll, Diane M. Becker, James G. Wilson, Guillaume Lettre, Alexander P. Reiner
Hum Mol Genet. 2013 Jun 15; 22(12): 2529–2538. Published online 2013 Feb 26. doi: 10.1093/hmg/ddt087
PMCID:
PMC3658166
AbstractArticlePDF–314K
14.
A Δ38 Deletion Variant of Human Transketolase as a Model of Transketolase-Like Protein 1 Exhibits No Enzymatic Activity
Stefan Schneider, Stefan Lüdtke, Kathrin Schröder-Tittmann, Cindy Wechsler, Danilo Meyer, Kai Tittmann
PLoS One. 2012; 7(10): e48321. Published online 2012 Oct 31. doi: 10.1371/journal.pone.0048321
PMCID:
PMC3485151
AbstractArticlePDF–740K
15.
Transketolase-Like 1 Expression Is Modulated during Colorectal Cancer Progression and Metastasis Formation
Santiago Diaz-Moralli, Miriam Tarrado-Castellarnau, Cristina Alenda, Antoni Castells, Marta Cascante
PLoS One. 2011; 6(9): e25323. Published online 2011 Sep 27. doi: 10.1371/journal.pone.0025323
PMCID:
PMC3181277
AbstractArticlePDF–1.3M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy
Juliana Schwaab, Karoline Horisberger, Philipp Ströbel, Beatrice Bohn, Deniz Gencer, Georg Kähler, Peter Kienle, Stefan Post, Frederik Wenz, Wolf-Karsten Hofmann, Ralf-Dieter Hofheinz, Philipp Erben
BMC Cancer. 2011; 11: 363. Published online 2011 Aug 19. doi: 10.1186/1471-2407-11-363
PMCID:
PMC3176245
AbstractArticlePDF–246K
18.
Lactate-Dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1
Gian Kayser, Ahmad Kassem, Wulf Sienel, Luzie Schulte-Uentrop, Dominik Mattern, Konrad Aumann, Elmar Stickeler, Martin Werner, Bernward Passlick, Axel zur Hausen
Diagn Pathol. 2010; 5: 22. Published online 2010 Apr 12. doi: 10.1186/1746-1596-5-22
PMCID:
PMC2861018
AbstractArticlePDF–1.2M
19.
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis via increased aerobic glycolysis and HIF1α stabilization
Wenyue Sun, Yan Liu, Chad A. Glazer, Chunbo Shao, Sheetal Bhan, Semra Demokan, Ming Zhao, Michelle A. Rudek, Patrick K. Ha, Joseph A. Califano
Clin Cancer Res. Author manuscript; available in PMC 2011 Feb 1.
Published in final edited form as: Clin Cancer Res. 2010 Feb 1; 16(3): 857–866. Published online 2010 Jan 26. doi: 10.1158/1078-0432.CCR-09-2604
PMCID:
PMC2824550
AbstractArticlePDF–2.9M
20.
Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia
Serena Sanna, Fabio Busonero, Andrea Maschio, Patrick F. McArdle, Gianluca Usala, Mariano Dei, Sandra Lai, Antonella Mulas, Maria Grazia Piras, Lucia Perseu, Marco Masala, Mara Marongiu, Laura Crisponi, Silvia Naitza, Renzo Galanello, Gonçalo R. Abecasis, Alan R. Shuldiner, David Schlessinger, Antonio Cao, Manuela Uda
Hum Mol Genet. 2009 Jul 15; 18(14): 2711–2718. Published online 2009 May 6. doi: 10.1093/hmg/ddp203
PMCID:
PMC2701337
AbstractArticlePDF–199K

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