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Select item 109546341.

Erythropoietin receptor signal is crucial for periodontal ligament stem cell-based tissue reconstruction in periodontal disease

MHD. Fouad Zakaria, Soichiro Sonoda, Hiroki Kato, Lan Ma, Norihisa Uehara, Yukari Kyumoto-Nakamura, M. Majd Sharifa, Liting Yu, Lisha Dai, Erika Yamauchi-Tomoda, Reona Aijima, Haruyoshi Yamaza, Fusanori Nishimura, Takayoshi Yamaza

Sci Rep. 2024; 14: 6719. Published online 2024 Mar 20. doi: 10.1038/s41598-024-57361-y

PMCID:: PMC10954634

Abstract Article PDF–8.7M

Select item 104998212.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 101272773.

Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox

Dirk H. Siepe, Lora K. Picton, K. Christopher Garcia

ACS Synth Biol. 2023 Apr 21; 12(4): 1081–1093. Published online 2023 Apr 3. doi: 10.1021/acssynbio.2c00587

PMCID:: PMC10127277

Abstract Article PDF–5.0M

Select item 98945744.

Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia

June Takeda, Kenichi Yoshida, Masahiro M. Nakagawa, Yasuhito Nannya, Akinori Yoda, Ryunosuke Saiki, Yotaro Ochi, Lanying Zhao, Rurika Okuda, Xingxing Qi, Takuto Mori, Ayana Kon, Kenichi Chiba, Hiroko Tanaka, Yuichi Shiraishi, Ming-Chung Kuo, Cassandra M. Kerr, Yasunobu Nagata, Daisuke Morishita, Nobuhiro Hiramoto, Akira Hangaishi, Hideyuki Nakazawa, Ken Ishiyama, Satoru Miyano, Shigeru Chiba, Yasushi Miyazaki, Toshiyuki Kitano, Kensuke Usuki, Nobuo Sezaki, Hisashi Tsurumi, Shuichi Miyawaki, Jaroslaw P. Maciejewski, Takayuki Ishikawa, Kazuma Ohyashiki, Arnold Ganser, Michael Heuser, Felicitas Thol, Lee-Yung Shih, Akifumi Takaori-Kondo, Hideki Makishima, Seishi Ogawa

Blood Cancer Discov. 2022 Sep 6; 3(5): 410–427. Published online 2022 Jul 14. doi: 10.1158/2643-3230.BCD-21-0192

PMCID:: PMC9894574

Abstract Article PDF–9.7M

Select item 86834745.

EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis

Daniel Hidalgo, Jacob Bejder, Ramona Pop, Kyle Gellatly, Yung Hwang, S. Maxwell Scalf, Anna E. Eastman, Jane-Jane Chen, Lihua Julie Zhu, Jules A. A. C. Heuberger, Shangqin Guo, Mark J. Koury, Nikolai Baastrup Nordsborg, Merav Socolovsky

Nat Commun. 2021; 12: 7334. Published online 2021 Dec 17. doi: 10.1038/s41467-021-27562-4

PMCID:: PMC8683474

Abstract Article PDF–3.5M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74503307.

Identification and Functional Analysis of EPOR⁺ Tumor-Associated Macrophages in Human Osteosarcoma Lung Metastasis

Yanxing Li, Ming Li, Rong Wei, Junlong Wu

J Immunol Res. 2020; 2020: 9374240. Published online 2020 Aug 18. doi: 10.1155/2020/9374240

PMCID:: PMC7450330

Abstract Article PDF–1.8M

Select item 74060898.

Upregulation of erythropoietin and erythropoietin receptor in castration-resistant progression of prostate cancer

Chen Ye, Guang-Hua Chen, Xin Chen, Sheng-Fei Qin, Min-Feng Shi, Tie Zhou

Asian J Androl. 2020 Jul-Aug; 22(4): 422–426. Published online 2019 Aug 9. doi: 10.4103/aja.aja_80_19

PMCID:: PMC7406089

Abstract Article PDF–1.9M

Select item 73796659.

Genetic variants of erythropoietin (EPO) and EPO receptor genes in familial erythrocytosis

Danijela Vočanec, Tinkara Prijatelj, Nataša Debeljak, Tanja Kunej

Int J Lab Hematol. 2019 Apr; 41(2): 162–167. Published online 2018 Dec 3. doi: 10.1111/ijlh.12949

PMCID:: PMC7379665

Abstract Article PDF–681K

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 640906711.

Vasculogenic Mimicry Formation Is Associated with Erythropoietin Expression but Not with Erythropoietin Receptor Expression in Cervical Squamous Cell Carcinoma

Yue-Jie Li, Xin Qing, Qing-Xu Tao, Li Xiang, Li Gong, Tie-Jun Zhou

Biomed Res Int. 2019; 2019: 1934195. Published online 2019 Feb 21. doi: 10.1155/2019/1934195

PMCID:: PMC6409067

Abstract Article PDF–6.6M

Select item 631897112.

Methylation of the first exon in the erythropoietin receptor gene does not correlate with its mRNA and protein level in cancer cells

Barbora Fecková, Patrícia Kimáková, Lenka Ilkovičová, Erika Szentpéteriová, Mária Macejová, Ján Košuth, Anthony Zulli, Nataša Debeljak, Petra Hudler, Karin Jašek, Ivana Kašubová, Peter Kubatka, Peter Solár

BMC Genet. 2019; 20: 1. Published online 2019 Jan 3. doi: 10.1186/s12863-018-0706-8

PMCID:: PMC6318971

Abstract Article PDF–1.0M

Select item 616668213.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 607849414.

Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation

Ryan D Ferrao, Heidi JA Wallweber, Patrick J Lupardus

eLife. 2018; 7: e38089. Published online 2018 Jul 25. doi: 10.7554/eLife.38089

PMCID:: PMC6078494

Abstract Article PDF–4.7M

Select item 603987015.

LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells

Philipp Trepte, Sabrina Kruse, Simona Kostova, Sheila Hoffmann, Alexander Buntru, Anne Tempelmeier, Christopher Secker, Lisa Diez, Aline Schulz, Konrad Klockmeier, Martina Zenkner, Sabrina Golusik, Kirstin Rau, Sigrid Schnoegl, Craig C Garner, Erich E Wanker

Mol Syst Biol. 2018 Jul; 14(7): e8071. Published online 2018 Jul 11. doi: 10.15252/msb.20178071

PMCID:: PMC6039870

Abstract Article PDF–2.1M

Select item 596675816.

Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a “U-shaped” relationship

Mingjun Shi, Brianna Flores, Peng Li, Nancy Gillings, Kathryn L. McMillan, Jianfeng Ye, Lily Jun-Shen Huang, Sachdev S. Sidhu, Yong-Ping Zhong, Maria T. Grompe, Philip R. Streeter, Orson W. Moe, Ming Chang Hu

Am J Physiol Renal Physiol. 2018 Apr 1; 314(4): F501–F516. Published online 2017 Nov 29. doi: 10.1152/ajprenal.00306.2017

PMCID:: PMC5966758

Abstract Article

Select item 578940617.

Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor

Shadi Khalil, Lorrie Delehanty, Stephen Grado, Maja Holy, Zollie White, III, Katie Freeman, Ryo Kurita, Yukio Nakamura, Grant Bullock, Adam Goldfarb

J Exp Med. 2018 Feb 5; 215(2): 661–679. doi: 10.1084/jem.20170396

PMCID:: PMC5789406

Abstract Article PDF–3.0M

Select item 577718918.

Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models

Jieyu Wang, Yoshihiro Hayashi, Asumi Yokota, Zefeng Xu, Yue Zhang, Rui Huang, Xiaomei Yan, Hongyun Liu, Liping Ma, Mohammad Azam, James P. Bridges, Jose A. Cancelas, Theodosia A. Kalfa, Xiuli An, Zhijian Xiao, Gang Huang

Haematologica. 2018 Jan; 103(1): 40–50. Prepublished online 2017 Oct 19. doi: 10.3324/haematol.2017.172775

PMCID:: PMC5777189

Abstract Article PDF–2.2M

Select item 559733319.

Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions

Li He, Helena Steinocher, Ashish Shelar, Emily B Cohen, Erin N Heim, Birthe B Kragelund, Gevorg Grigoryan, Daniel DiMaio

eLife. 2017; 6: e27701. Published online 2017 Sep 4. doi: 10.7554/eLife.27701

PMCID:: PMC5597333

Abstract Article PDF–1.2M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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