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Items: 1 to 20 of 59

1.
Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface
Amber Wilkerson, Seher Yuksel, Riya Acharya, Igor A. Butovich
Invest Ophthalmol Vis Sci. 2024 Jul; 65(8): 2. Published online 2024 Jul 2. doi: 10.1167/iovs.65.8.2
PMCID:
PMC11221616
AbstractArticlePDF–8.3M
2.
Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food
Laura Dearden, Isadora C. Furigo, Lucas C. Pantaleão, L W. P. Wong, Denise S. Fernandez-Twinn, Juliana de Almeida-Faria, Katherine A. Kentistou, Maria V. Carreira, Guillaume Bidault, Antonio Vidal-Puig, Ken K. Ong, John R. B. Perry, Jose Donato, Jr, Susan E. Ozanne
PLoS Biol. 2024 Jun; 22(6): e3002641. Published online 2024 Jun 4. doi: 10.1371/journal.pbio.3002641
PMCID:
PMC11149872
AbstractArticlePDF–1.7M
3.
Comparative Biophysical Study of Meibomian Lipids of Wild Type and Soat1-Null Mice: Implications to Meibomian Gland Dysfunction and Dry Eye Disease
Xiaojie Xu, Amber Wilkerson, Guangle Li, Igor A. Butovich, Yi Y. Zuo
Invest Ophthalmol Vis Sci. 2023 Aug; 64(11): 20. Published online 2023 Aug 16. doi: 10.1167/iovs.64.11.20
PMCID:
PMC10434715
AbstractArticlePDF–8.3M
4.
Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization
Syed A. H. Zaidi, Tahira Lemtalsi, Zhimin Xu, Isabella Santana, Porsche Sandow, Leila Labazi, Robert W. Caldwell, Ruth B. Caldwell, Modesto A. Rojas
J Neuroinflammation. 2023; 20: 14. Published online 2023 Jan 23. doi: 10.1186/s12974-023-02700-5
PMCID:
PMC9869542
AbstractArticlePDF–8.0M
5.
Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells
Maximillian A. Rogers, Catherine C. Y. Chang, Robert A. Maue, Elaina M. Melton, Andrew A. Peden, William S. Garver, Junghoon Lee, Peter Schroen, Mitchell Huang, Ta-Yuan Chang
Proc Natl Acad Sci U S A. 2022 May 3; 119(18): e2201646119. Published online 2022 May 4. doi: 10.1073/pnas.2201646119
PMCID:
PMC9170141
AbstractArticlePDF–2.7M
6.
Ceramide-mediated gut dysbiosis enhances cholesterol esterification and promotes colorectal tumorigenesis in mice
Yahui Zhu, Li Gu, Xi Lin, Jinmiao Zhang, Yi Tang, Xinyi Zhou, Bingjun Lu, Xingrong Lin, Cheng Liu, Edward V. Prochownik, Youjun Li
JCI Insight. 2022 Feb 8; 7(3): e150607. Published online 2022 Feb 8. doi: 10.1172/jci.insight.150607
PMCID:
PMC8855812
AbstractArticlePDF–15M
7.
Depletion of Cholesteryl Esters Causes Meibomian Gland Dysfunction-Like Symptoms in a Soat1-Null Mouse Model
Igor A. Butovich, Amber Wilkerson, Seher Yuksel
Int J Mol Sci. 2021 Feb; 22(4): 1583. Published online 2021 Feb 4. doi: 10.3390/ijms22041583
PMCID:
PMC7915537
AbstractArticlePDF–3.9M
8.
Soat1 mediates the mouse strain effects on cholesterol loading-induced endoplasmic reticulum stress and CHOP expression in macrophages
Mengdie Luo, Emmanuel Opoku, C. Alicia Traughber, Qimin Hai, Peggy Robinet, Stela Berisha, Jonathan D. Smith
Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jan; 1866(1): 158825. Published online 2020 Oct 6. doi: 10.1016/j.bbalip.2020.158825
PMCID:
PMC7686275
AbstractArticlePDF–881K
9.
Circ-Tulp4 promotes β-cell adaptation to lipotoxicity by regulating soat1 expression
Liting Wu, Li Xiong, Jin Li, Zishan Peng, Luyao Zhang, Peijie Shi, Yingying Gong, Haipeng Xiao
J Mol Endocrinol. 2020 Nov; 65(4): 149–161. Published online 2020 Sep 11. doi: 10.1530/JME-20-0079
PMCID:
PMC7576671
AbstractArticlePDF–3.5M
10.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
11.
A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression
Michishige Terasaki, Hironori Yashima, Yusaku Mori, Tomomi Saito, Takanori Matsui, Munenori Hiromura, Hideki Kushima, Naoya Osaka, Makoto Ohara, Tomoyasu Fukui, Tsutomu Hirano, Sho-ichi Yamagishi
Int J Mol Sci. 2020 Jul; 21(13): 4811. Published online 2020 Jul 7. doi: 10.3390/ijms21134811
PMCID:
PMC7369823
AbstractArticlePDF–991K
12.
Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection
Jinrui Xu, Yanbing Zhou, Yi Yang, Cuiping Lv, Xiaoming Liu, Yujiong Wang
BMC Immunol. 2020; 21: 26. Published online 2020 May 12. doi: 10.1186/s12865-020-00356-x
PMCID:
PMC7216371
AbstractArticlePDF–1.8M
13.
USP1 deubiquitinates Akt to inhibit PI3K‐Akt‐FoxO signaling in muscle during prolonged starvation
Dana Goldbraikh, Danielle Neufeld, Yara Eid‐Mutlak, Inbal Lasry, Jennifer E Gilda, Anna Parnis, Shenhav Cohen
EMBO Rep. 2020 Apr 3; 21(4): e48791. Published online 2020 Mar 5. doi: 10.15252/embr.201948791
PMCID:
PMC7132338
AbstractArticlePDF–1.6M
14.
Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions
Elaina M. Melton, Haibo Li, Jalen Benson, Paul Sohn, Li-Hao Huang, Bao-Liang Song, Bo-Liang Li, Catherine C. Y. Chang, Ta-Yuan Chang
J Biol Chem. 2019 Oct 25; 294(43): 15836–15849. Published online 2019 Sep 8. doi: 10.1074/jbc.RA119.010564
PMCID:
PMC6816086
AbstractArticlePDF–4.3M
15.
ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes
G. Michelle Ducasa, Alla Mitrofanova, Shamroop K. Mallela, Xiaochen Liu, Judith Molina, Alexis Sloan, Christopher E. Pedigo, Mengyuan Ge, Javier Varona Santos, Yanio Hernandez, Jin-Ju Kim, Cyrille Maugeais, Armando J. Mendez, Viji Nair, Matthias Kretzler, George W. Burke, Robert G. Nelson, Yu Ishimoto, Reiko Inagi, Santanu Banerjee, Shaoyi Liu, Hazel H. Szeto, Sandra Merscher, Flavia Fontanesi, Alessia Fornoni
J Clin Invest. 2019 Aug 1; 129(8): 3387–3400. Published online 2019 Jul 22. doi: 10.1172/JCI125316
PMCID:
PMC6668702
AbstractArticlePDF–11M
16.
Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells
Hisataka Yamazaki, Manabu Takahashi, Tetsuji Wakabayashi, Kent Sakai, Daisuke Yamamuro, Akihito Takei, Shoko Takei, Shuichi Nagashima, Hiroaki Yagyu, Motohiro Sekiya, Ken Ebihara, Shun Ishibashi
J Atheroscler Thromb. 2019 Mar 1; 26(3): 246–259. doi: 10.5551/jat.44040
PMCID:
PMC6402884
AbstractArticlePDF–1.4M
17.
Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity
Li-Hao Huang, Elaina M. Melton, Haibo Li, Paul Sohn, DaeYoung Jung, Ching-Yi Tsai, Tian Ma, Hiroyuki Sano, HyeKyung Ha, Randall H. Friedline, Jason K. Kim, Edward Usherwood, Catherine C. Y. Chang, Ta-Yuan Chang
Am J Physiol Endocrinol Metab. 2018 Sep 1; 315(3): E340–E356. Published online 2018 Mar 13. doi: 10.1152/ajpendo.00174.2017
PMCID:
PMC6171008
AbstractArticle
18.
In vitro exploration of ACAT contributions to lipid droplet formation during adipogenesis
Yuyan Zhu, Chih-Yu Chen, Junjie Li, Ji-Xin Cheng, Miran Jang, Kee-Hong Kim
J Lipid Res. 2018 May; 59(5): 820–829. Published online 2018 Mar 16. doi: 10.1194/jlr.M081745
PMCID:
PMC5928425
AbstractArticlePDF–1.1M
19.
QTL Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant
Qimin Hai, Brian Ritchey, Peggy Robinet, Alexander M. Alzayed, Greg Brubaker, Jinying Zhang, Jonathan D. Smith
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Jan; 38(1): 83–91. Published online 2017 Nov 2. doi: 10.1161/ATVBAHA.117.310173
PMCID:
PMC5746475
AbstractArticlePDF–1002K
20.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong
EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500
PMCID:
PMC5341520
AbstractArticlePDF–1.1M

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