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Items: 1 to 20 of 90

1.
Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms
Arjun Muralidharan, Alexander Samoshkin, Marino Convertino, Marjo Hannele Piltonen, Pavel Gris, Jian Wang, Changyu Jiang, Richard Klares, III, Alexander Linton, Ru-Rong Ji, William Maixner, Nikolay V. Dokholyan, Jeffrey S. Mogil, Luda Diatchenko
Br J Pharmacol. Author manuscript; available in PMC 2023 Dec 5.
Published in final edited form as: Br J Pharmacol. 2021 Jul; 178(13): 2709–2726. Published online 2021 Apr 30. doi: 10.1111/bph.15463
PMCID:
PMC10697213
AbstractArticlePDF–2.1M
2.
Early-life adversity increases morphine tolerance and persistent inflammatory hypersensitivity through upregulation of δ opioid receptors in mice
Sam Singleton, Claire Sneddon, Alice Bakina, Jeremy J. Lambert, Tim G. Hales
Pain. 2023 Oct; 164(10): 2253–2264. Published online 2023 May 10. doi: 10.1097/j.pain.0000000000002925
PMCID:
PMC10502877
AbstractArticlePDF–910K
3.
Distribution of delta and mu opioid receptor mRNA in rodent dorsal root ganglia neurons
Béatrice Quirion, Claudie Beaulieu, Laurie Côté, Jean‐Luc Parent, Louis Gendron
Eur J Neurosci. 2022 Aug; 56(3): 4031–4044. Published online 2022 Jun 14. doi: 10.1111/ejn.15733
PMCID:
PMC9543299
AbstractArticlePDF–67M
4.
Delta opioid receptors on nociceptive sensory neurons mediate peripheral endogenous analgesia in colitis
Xavier Mas-Orea, Lilian Basso, Catherine Blanpied, Claire Gaveriaux-Ruff, Nicolas Cenac, Gilles Dietrich
J Neuroinflammation. 2022; 19: 7. Published online 2022 Jan 6. doi: 10.1186/s12974-021-02352-3
PMCID:
PMC8740424
AbstractArticlePDF–1.8M
5.
Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons
Xinyi Jenny He, Janki Patel, Connor E Weiss, Xiang Ma, Brenda L Bloodgood, Matthew R Banghart
eLife. 2021; 10: e69746. Published online 2021 Nov 17. doi: 10.7554/eLife.69746
PMCID:
PMC8716102
AbstractArticlePDF–5.0M
6.
A functional topography within the cholinergic basal forebrain for encoding sensory cues and behavioral reinforcement outcomes
Blaise Robert, Eyal Y Kimchi, Yurika Watanabe, Tatenda Chakoma, Miao Jing, Yulong Li, Daniel B Polley
eLife. 2021; 10: e69514. Published online 2021 Nov 25. doi: 10.7554/eLife.69514
PMCID:
PMC8654357
AbstractArticlePDF–8.9M
7.
Delta Opioid Receptor in Astrocytes Contributes to Neuropathic Cold Pain and Analgesic Tolerance in Female Mice
David Reiss, Hervé Maurin, Emilie Audouard, Miriam Martínez-Navarro, Yaping Xue, Yann Herault, Rafael Maldonado, David Cabañero, Claire Gaveriaux-Ruff
Front Cell Neurosci. 2021; 15: 745178. Published online 2021 Sep 16. doi: 10.3389/fncel.2021.745178
PMCID:
PMC8483180
AbstractArticlePDF–1.9M
8.
Switching of delta opioid receptor subtypes in central amygdala microcircuits is associated with anxiety states in pain
Wenjie Zhou, Yanhua Li, Xiaojing Meng, An Liu, Yu Mao, Xia Zhu, Qian Meng, Yan Jin, Zhi Zhang, Wenjuan Tao
J Biol Chem. 2021 Jan-Jun; 296: 100277. Published online 2021 Jan 9. doi: 10.1016/j.jbc.2021.100277
PMCID:
PMC7948800
AbstractArticlePDF–3.3M
9.
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, András Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar
eLife. 2021; 10: e56519. Published online 2021 Feb 8. doi: 10.7554/eLife.56519
PMCID:
PMC7909954
AbstractArticlePDF–12M
10.
Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia
Isaac J. Dripps, Zachariah Bertels, Laura S. Moye, Alycia F. Tipton, Kendra Siegersma, Serapio M. Baca, Brigitte L. Kieffer, Amynah A. Pradhan
Sci Rep. 2020; 10: 17629. Published online 2020 Oct 19. doi: 10.1038/s41598-020-74605-9
PMCID:
PMC7573615
AbstractArticlePDF–2.3M
11.
Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain
Nestor N. Jimenez-Vargas, Jing Gong, Matthew J. Wisdom, Dane D. Jensen, Rocco Latorre, Alan Hegron, Shavonne Teng, Jesse J. DiCello, Pradeep Rajasekhar, Nicholas A. Veldhuis, Simona E. Carbone, Yang Yu, Cintya Lopez-Lopez, Josue Jaramillo-Polanco, Meritxell Canals, David E. Reed, Alan E. Lomax, Brian L. Schmidt, Kam W. Leong, Stephen J. Vanner, Michelle L. Halls, Nigel W. Bunnett, Daniel P. Poole
Proc Natl Acad Sci U S A. 2020 Jun 30; 117(26): 15281–15292. Published online 2020 Jun 16. doi: 10.1073/pnas.2000500117
PMCID:
PMC7334524
AbstractArticlePDF–2.6M
12.
In vivo mapping of a GPCR interactome using knockin mice
Jade Degrandmaison, Khaled Abdallah, Véronique Blais, Samuel Génier, Marie-Pier Lalumière, Francis Bergeron, Catherine M. Cahill, Jim Boulter, Christine L. Lavoie, Jean-Luc Parent, Louis Gendron
Proc Natl Acad Sci U S A. 2020 Jun 9; 117(23): 13105–13116. Published online 2020 May 26. doi: 10.1073/pnas.1917906117
PMCID:
PMC7293596
AbstractArticlePDF–1.8M
13.
Activation of μ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents
Vinod Tiwari, Shao-Qiu He, Qian Huang, Lingli Liang, Fei Yang, Zhiyong Chen, Vineeta Tiwari, Wakako Fujita, Lakshmi A. Devi, Xinzhong Dong, Yun Guan, Srinivasa N. Raja
Pain. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: Pain. 2020 Apr; 161(4): 842–855. doi: 10.1097/j.pain.0000000000001768
PMCID:
PMC7085422
AbstractArticlePDF–693K
14.
Peripheral Delta Opioid Receptors Mediate Formoterol Anti-allodynic Effect in a Mouse Model of Neuropathic Pain
Rhian Alice Ceredig, Florian Pierre, Stéphane Doridot, Unai Alduntzin, Pierre Hener, Eric Salvat, Ipek Yalcin, Claire Gaveriaux-Ruff, Michel Barrot, Dominique Massotte
Front Mol Neurosci. 2019; 12: 324. Published online 2020 Feb 14. doi: 10.3389/fnmol.2019.00324
PMCID:
PMC7033630
AbstractArticlePDF–5.0M
15.
Developmental Expression of the μ, κ, and δ Opioid Receptor mRNAs in Mouse
Yanxin Zhu, Ming-Sing Hsu, John E. Pintar
J Neurosci. 1998 Apr 1; 18(7): 2538–2549. doi: 10.1523/JNEUROSCI.18-07-02538.1998
PMCID:
PMC6793117
AbstractArticlePDF–3.1M
16.
Motivational Effects of Cannabinoids Are Mediated by μ-Opioid and κ-Opioid Receptors
Sandy Ghozland, Hans W. D. Matthes, Frederic Simonin, Dominique Filliol, Brigitte L. Kieffer, Rafael Maldonado
J Neurosci. 2002 Feb 1; 22(3): 1146–1154. doi: 10.1523/JNEUROSCI.22-03-01146.2002
PMCID:
PMC6758535
AbstractArticlePDF–155K
17.
Genetic Dissociation of Opiate Tolerance and Physical Dependence in δ-Opioid Receptor-1 and Preproenkephalin Knock-Out Mice
Joshua F. Nitsche, Alwin G. P. Schuller, Michael A. King, Min Zengh, Gavril W. Pasternak, John E. Pintar
J Neurosci. 2002 Dec 15; 22(24): 10906–10913. doi: 10.1523/JNEUROSCI.22-24-10906.2002
PMCID:
PMC6758444
AbstractArticlePDF–360K
18.
Tlx1/3 and Ptf1a Control the Expression of Distinct Sets of Transmitter and Peptide Receptor Genes in the Developing Dorsal Spinal Cord
Zhen Guo, Congling Zhao, Menggui Huang, Tianwen Huang, Mingran Fan, Zhiqin Xie, Ying Chen, Xiaolin Zhao, Guannan Xia, Junlan Geng, Leping Cheng
J Neurosci. 2012 Jun 20; 32(25): 8509–8520. doi: 10.1523/JNEUROSCI.6301-11.2012
PMCID:
PMC6620993
AbstractArticlePDF–5.6M
19.
T-Cell Mediation of Pregnancy Analgesia Affecting Chronic Pain in Mice
Sarah F. Rosen, Boram Ham, Shannon Drouin, Nadia Boachie, Anne-Julie Chabot-Dore, Jean-Sebastien Austin, Luda Diatchenko, Jeffrey S. Mogil
J Neurosci. 2017 Oct 11; 37(41): 9819–9827. doi: 10.1523/JNEUROSCI.2053-17.2017
PMCID:
PMC6596598
AbstractArticlePDF–1.6M
20.
A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline
Mélanie Kremer, Ipek Yalcin, Yannick Goumon, Xavier Wurtz, Laurent Nexon, Dorothée Daniel, Salim Megat, Rhian A. Ceredig, Carl Ernst, Gustavo Turecki, Virginie Chavant, Jean-François Théroux, Adrien Lacaud, Lauriane-Elisabeth Joganah, Vincent Lelievre, Dominique Massotte, Pierre-Eric Lutz, Ralf Gilsbach, Eric Salvat, Michel Barrot
J Neurosci. 2018 Nov 14; 38(46): 9934–9954. doi: 10.1523/JNEUROSCI.1004-18.2018
PMCID:
PMC6596240
AbstractArticlePDF–1.5M

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