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Items: 1 to 20 of 31

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling
Anna Janovicz, Aliz Majer, Mónika Kosztelnik, Miklós Geiszt, Jerold Chun, Satoshi Ishii, Gábor József Tigyi, Zoltán Benyó, Éva Ruisanchez
Exp Biol Med (Maywood) 2023 Oct; 248(20): 1887–1894. Published online 2023 Oct 14. doi: 10.1177/15353702231199081
PMCID:
PMC10792427
AbstractArticlePDF–1.0M
3.
GPR92 activation in islet macrophages controls β cell function in a diet-induced obesity model
Camila O. de Souza, Vivian A. Paschoal, Xuenan Sun, Lavanya Vishvanath, Qianbin Zhang, Mengle Shao, Toshiharu Onodera, Shiuhwei Chen, Nolwenn Joffin, Lorena M.A. Bueno, Rana K. Gupta, Da Young Oh
J Clin Invest. 2022 Nov 1; 132(21): e160097. Published online 2022 Nov 1. doi: 10.1172/JCI160097
PMCID:
PMC9621135
AbstractArticlePDF–7.0M
4.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
5.
Lysophosphatidic Acid Receptor 5 (LPA5) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro
Lisha Joshi, Ioanna Plastira, Eva Bernhart, Helga Reicher, Zhanat Koshenov, Wolfgang F. Graier, Nemanja Vujic, Dagmar Kratky, Richard Rivera, Jerold Chun, Wolfgang Sattler
Cells. 2022 Apr; 11(7): 1071. Published online 2022 Mar 22. doi: 10.3390/cells11071071
PMCID:
PMC8998093
AbstractArticlePDF–2.8M
6.
Inhibition of Autotaxin and Lysophosphatidic Acid Receptor 5 Attenuates Neuroinflammation in LPS-Activated BV-2 Microglia and a Mouse Endotoxemia Model
Lisha Joshi, Ioanna Plastira, Eva Bernhart, Helga Reicher, Alexander Triebl, Harald C. Köfeler, Wolfgang Sattler
Int J Mol Sci. 2021 Aug; 22(16): 8519. Published online 2021 Aug 7. doi: 10.3390/ijms22168519
PMCID:
PMC8395174
AbstractArticlePDF–3.4M
7.
Control of Intestinal Epithelial Permeability by Lysophosphatidic Acid Receptor 5
Mo Wang, Peijian He, Yiran Han, Lei Dong, C. Chris Yun
Cell Mol Gastroenterol Hepatol. 2021; 12(3): 1073–1092. Published online 2021 May 8. doi: 10.1016/j.jcmgh.2021.05.003
PMCID:
PMC8350072
AbstractArticlePDF–5.8M
8.
Altered cleavage plane orientation with increased genomic aneuploidy produced by receptor-mediated lysophosphatidic acid (LPA) signaling in mouse cerebral cortical neural progenitor cells
Whitney S. McDonald, Kyoko Miyamoto, Richard Rivera, Grace Kennedy, Beatriz S. V. Almeida, Marcy A. Kingsbury, Jerold Chun
Mol Brain. 2020; 13: 169. Published online 2020 Dec 14. doi: 10.1186/s13041-020-00709-y
PMCID:
PMC7734743
AbstractArticlePDF–2.1M
9.
Lysophosphatidic Acid Receptor 5 Contributes to Imiquimod-Induced Psoriasis-Like Lesions through NLRP3 Inflammasome Activation in Macrophages
Bhakta Prasad Gaire, Chi-Ho Lee, Wondong Kim, Arjun Sapkota, Do Yup Lee, Ji Woong Choi
Cells. 2020 Aug; 9(8): 1753. Published online 2020 Jul 22. doi: 10.3390/cells9081753
PMCID:
PMC7465035
AbstractArticlePDF–4.3M
10.
Lysophosphatidic Acid Receptor 5 Plays a Pathogenic Role in Brain Damage after Focal Cerebral Ischemia by Modulating Neuroinflammatory Responses
Arjun Sapkota, Chi-Ho Lee, Se Jin Park, Ji Woong Choi
Cells. 2020 Jun; 9(6): 1446. Published online 2020 Jun 10. doi: 10.3390/cells9061446
PMCID:
PMC7348986
AbstractArticlePDF–4.8M
11.
LPA1/3 overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction
Nicole C. Lummis, Paloma Sánchez-Pavón, Grace Kennedy, Aaron J. Frantz, Yasuyuki Kihara, Victoria A. Blaho, Jerold Chun
Sci Adv. 2019 Oct; 5(10): eaax2011. Published online 2019 Oct 9. doi: 10.1126/sciadv.aax2011
PMCID:
PMC6785248
AbstractArticlePDF–9.3M
12.
LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling
Divij Mathew, Kimberly N. Kremer, Pamela Strauch, Gabor Tigyi, Roberta Pelanda, Raul M. Torres
Front Immunol. 2019; 10: 1159. Published online 2019 May 28. doi: 10.3389/fimmu.2019.01159
PMCID:
PMC6558414
AbstractArticlePDF–2.7M
13.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
14.
Expression of lysophosphatidic acid receptor 5 is necessary for the regulation of intestinal Na+/H+ exchanger 3 by lysophosphatidic acid in vivo
Kayte A. Jenkin, Peijian He, C. Chris Yun
Am J Physiol Gastrointest Liver Physiol. 2018 Oct 1; 315(4): G433–G442. Published online 2018 May 24. doi: 10.1152/ajpgi.00130.2018
PMCID:
PMC6230692
AbstractArticle
15.
Apolipoprotein A-IV enhances cholecystokinin secretion
Jesse Zhan, Jonathan Weng, Brian G Hunt, W. Sean Davidson, Min Liu, Chunmin C Lo
Physiol Behav. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Physiol Behav. 2018 May 1; 188: 11–17. Published online 2018 Jan 31. doi: 10.1016/j.physbeh.2018.01.019
PMCID:
PMC5845788
AbstractArticlePDF–556K
16.
Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models
Syuji Kurogi, Tomohisa Sekimoto, Taro Funamoto, Tomomi Ota, Shihoko Nakamura, Takuya Nagai, Mai Nakahara, Kumiko Yoshinobu, Kimi Araki, Masatake Araki, Etsuo Chosa
Sci Rep. 2017; 7: 40692. Published online 2017 Jan 20. doi: 10.1038/srep40692
PMCID:
PMC5247747
AbstractArticlePDF–1.9M
17.
Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility
Akira Takeda, Daichi Kobayashi, Keita Aoi, Naoko Sasaki, Yuki Sugiura, Hidemitsu Igarashi, Kazuo Tohya, Asuka Inoue, Erina Hata, Noriyuki Akahoshi, Haruko Hayasaka, Junichi Kikuta, Elke Scandella, Burkhard Ludewig, Satoshi Ishii, Junken Aoki, Makoto Suematsu, Masaru Ishii, Kiyoshi Takeda, Sirpa Jalkanen, Masayuki Miyasaka, Eiji Umemoto
eLife. 2016; 5: e10561. Published online 2016 Feb 2. doi: 10.7554/eLife.10561
PMCID:
PMC4755752
AbstractArticlePDF–5.8M
18.
Autotaxin, LPA Receptors (1 and 5) Exert Disparate Functions in Tumor Cells Versus the Host Tissue Microenvironment in Melanoma Invasion and Metastasis
Sue-Chin Lee, Yuko Fujiwara, Jianxiong Liu, Junming Yue, Yoshibumi Shimizu, Derek D. Norman, Yaohong Wang, Ryoko Tsukahara, Erzsebet Szabo, Renukadevi Patil, Souvik Banerjee, Duane D. Miller, Louisa Balazs, Manik C. Ghosh, Christopher M. Waters, Tamas Oravecz, Gabor J. Tigyi
Mol Cancer Res. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Mol Cancer Res. 2015 Jan; 13(1): 174–185. Published online 2014 Aug 26. doi: 10.1158/1541-7786.MCR-14-0263
PMCID:
PMC4297753
AbstractArticlePDF–1.4M
19.
Lysophosphatidic Acid (LPA) Receptor 5 Inhibits B Cell Antigen Receptor Signaling and Antibody Response
Jiancheng Hu, Shannon K. Oda, Kristin Shotts, Erin E. Donovan, Pamela Strauch, Lindsey M. Pujanauski, Francisco Victorino, Amin Al-Shami, Yuko Fujiwara, Gabor Tigyi, Tamas Oravecz, Roberta Pelanda, Raul M. Torres
J Immunol. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: J Immunol. 2014 Jul 1; 193(1): 85–95. Published online 2014 Jun 2. doi: 10.4049/jimmunol.1300429
PMCID:
PMC4128188
AbstractArticlePDF–1.8M
20.
Lysophospholipid receptor nomenclature review: IUPHAR Review 8
Yasuyuki Kihara, Michael Maceyka, Sarah Spiegel, Jerold Chun
Br J Pharmacol. 2014 Aug; 171(15): 3575–3594. Published online 2014 Jul 12. doi: 10.1111/bph.12678
PMCID:
PMC4128058
AbstractArticlePDF–1.2M

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