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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95745153.

A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert

J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484

PMCID:: PMC9574515

Abstract Article PDF–1.8M

Select item 94819334.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 87488735.

Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy

Tiffany Chern, Annita Achilleos, Xuefei Tong, Matthew C. Hill, Alexander B. Saltzman, Lucas C. Reineke, Arindam Chaudhury, Swapan K. Dasgupta, Yushi Redhead, David Watkins, Joel R. Neilson, Perumal Thiagarajan, Jeremy B. A. Green, Anna Malovannaya, James F. Martin, David S. Rosenblatt, Ross A. Poché

Nat Commun. 2022; 13: 134. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27759-7

PMCID:: PMC8748873

Abstract Article PDF–11M

Select item 82666176.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159918.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 72999589.

Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

Yaping Li, Baohua Huang, Hua Yang, Shuang Kan, Yanling Yao, Xin Liu, Shiming Pu, Guozhang He, Taj-Malook Khan, Guangying Qi, Zuping Zhou, Wei Shu, Ming Chen

Sci Rep. 2020; 10: 9868. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66789-x

PMCID:: PMC7299958

Abstract Article PDF–2.7M

Select item 723606010.

Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism

Arielle N. Valdez-Sinon, Austin Lai, Liang Shi, Carly L. Lancaster, Avanti Gokhale, Victor Faundez, Gary J. Bassell

iScience. 2020 May 22; 23(5): 101132. Published online 2020 May 1. doi: 10.1016/j.isci.2020.101132

PMCID:: PMC7236060

Abstract Article PDF–6.1M

Select item 655472311.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner

Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler

J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.

Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027

PMCID:: PMC6554723

Abstract Article PDF–2.0M

Select item 629804012.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 606970513.

RNA binding proteins co-localize with small tau inclusions in tauopathy

Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin

Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5

PMCID:: PMC6069705

Abstract Article PDF–5.5M

Select item 579902314.

Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue

Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce

Cell Syst. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017

PMCID:: PMC5799023

Abstract Article PDF–730K

Select item 561195515.

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development

Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon

Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112

PMCID:: PMC5611955

Abstract Article

Select item 538122616.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 534567317.

Ribosomal protein S3 gene silencing protects against experimental allergic asthma

Jinrui Dong, Wupeng Liao, Hong Yong Peh, Tze Khee Chan, W S Daniel Tan, Li Li, Amy Yong, W S Fred Wong

Br J Pharmacol. 2017 Apr; 174(7): 540–552. Published online 2017 Feb 24. doi: 10.1111/bph.13717

PMCID:: PMC5345673

Abstract Article PDF–2.1M

Select item 532570218.

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity

Tara Vanderweyde, Daniel J. Apicco, Katherine Youmans-Kidder, Peter E.A. Ash, Casey Cook, Edroaldo Lummertz da Rocha, Karen Jansen-West, Alissa A. Frame, Allison Citro, John D. Leszyk, Pavel Ivanov, Jose F. Abisambra, Martin Steffen, Hu Li, Leonard Petrucelli, Benjamin Wolozin

Cell Rep. Author manuscript; available in PMC 2017 Feb 24.

Published in final edited form as: Cell Rep. 2016 May 17; 15(7): 1455–1466. Published online 2016 May 6. doi: 10.1016/j.celrep.2016.04.045

PMCID:: PMC5325702

Abstract Article PDF–2.1M

Select item 497021319.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 478790320.

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes

Markus M. Rinschen, Puneet Bharill, Xiongwu Wu, Priyanka Kohli, Matthäus J. Reinert, Oliver Kretz, Isabel Saez, Bernhard Schermer, Martin Höhne, Malte P. Bartram, Sriram Aravamudhan, Bernard R. Brooks, David Vilchez, Tobias B. Huber, Roman-Ulrich Müller, Marcus Krüger, Thomas Benzing

Hum Mol Genet. 2016 Apr 1; 25(7): 1328–1344. Published online 2016 Jan 19. doi: 10.1093/hmg/ddw016

PMCID:: PMC4787903

Abstract Article PDF–1.0M

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