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Items: 1 to 20 of 223

1.
LYP regulates SLP76 and other adaptor proteins in T cells
Virginia Ruiz-Martín, Tamara Marcos, José María de Pereda, Mariano Sánchez-Crespo, Miguel Angel de la Fuente, Yolanda Bayón, Andrés Alonso
Biol Res. 2024; 57: 69. Published online 2024 Sep 28. doi: 10.1186/s40659-024-00536-8
PMCID:
PMC11438317
AbstractArticlePDF–2.3M
2.
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling
Chuling Zhuang, Shen Yang, Carlos G. Gonzalez, Richard I. Ainsworth, Sheng Li, Masumi Takayama Kobayashi, Igor Wierzbicki, Leigh-Ana M. Rossitto, Yutao Wen, Wolfgang Peti, Stephanie M. Stanford, David J. Gonzalez, Ramachandran Murali, Eugenio Santelli, Nunzio Bottini
J Biol Chem. 2024 Jun; 300(6): 107393. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107393
PMCID:
PMC11237943
AbstractArticlePDF–2.9M
3.
Association between PYTPN22 rs2476601, VEGF rs833070, TNFAIP3 rs6920220 Polymorphisms and Risk for Rheumatoid Arthritis in Early Undifferentiated Arthritis Patients: A Pilot Study
Regina Sakalyte, Sigita Stropuviene, Gabija Jasionyte, Loreta Bagdonaite, Algirdas Venalis
Medicina (Kaunas) 2023 Oct; 59(10): 1824. Published online 2023 Oct 13. doi: 10.3390/medicina59101824
PMCID:
PMC10607990
AbstractArticlePDF–323K
4.
CircPTPN22 modulates T-cell activation by sponging miR-4689 to regulate S1PR1 expression in patients with systemic lupus erythematosus
Zhuyan Jiang, Shifei Li, Yuying Jia, Qijun Wu, Xuemeng Chen, Mengjie Zhang, Qingqing Miao, Zhiting Zhong, Zhifang Zhai, Bing Ni, Jun Xiao, Jun Tang
Arthritis Res Ther. 2023; 25: 206. Published online 2023 Oct 19. doi: 10.1186/s13075-023-03150-3
Correction in:
Arthritis Res Ther. 2024; 26: 39.
PMCID:
PMC10585821
AbstractArticlePDF–2.6M
5.
Targeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve interstitial cells and aortic valve lesions in mice
Shunyi Li, Zichao Luo, Shuwen Su, Liming Wen, Gaopeng Xian, Jing Zhao, Xingbo Xu, Dingli Xu, Qingchun Zeng
BMC Med. 2023; 21: 252. Published online 2023 Jul 13. doi: 10.1186/s12916-023-02888-6
PMCID:
PMC10347738
AbstractArticlePDF–14M
6.
PTPN22 intron polymorphism rs1310182 (c.2054-852T>C) is associated with type 1 diabetes mellitus in patients of Armenian descent
Robert Žak, Lusine Navasardyan, Ján Hunák, Jiřina Martinů, Petr Heneberg
PLoS One. 2023; 18(6): e0286743. Published online 2023 Jun 14. doi: 10.1371/journal.pone.0286743
PMCID:
PMC10266637
AbstractArticlePDF–532K
7.
The association between PTPN22 C1858T gene polymorphism and type 1 diabetes mellitus: an Indonesian study
Nur Rochmah, Fatimah Arief, Muhammad Faizi, Sukmawati Basuki
Ann Med. 2023; 55(1): 1211–1215. Published online 2023 Mar 24. doi: 10.1080/07853890.2023.2190162
PMCID:
PMC10044151
AbstractArticlePDF–504K
8.
FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia
Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen
J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0
PMCID:
PMC9922468
AbstractArticlePDF–4.9M
9.
HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults
Nishtha Ahuja, Jagdeep Singh, Ranjana Walker Minz, Shashi Anand, Ashim Das, Sunil Taneja
Front Immunol. 2022; 13: 984083. Published online 2023 Jan 18. doi: 10.3389/fimmu.2022.984083
PMCID:
PMC9891307
AbstractArticlePDF–1.2M
10.
Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review
Kalthoum Tizaoui, Jae Il Shin, Gwang Hun Jeong, Jae Won Yang, Seoyeon Park, Ji Hong Kim, Soo Young Hwang, Se Jin Park, Ai Koyanagi, Lee Smith
Medicina (Kaunas) 2022 Aug; 58(8): 1034. Published online 2022 Aug 2. doi: 10.3390/medicina58081034
PMCID:
PMC9415475
AbstractArticlePDF–390K
11.
SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 binding
Ben F. Brian, IV, Frances V. Sjaastad, Tanya S. Freedman
Sci Rep. 2022; 12: 5875. Published online 2022 Apr 7. doi: 10.1038/s41598-022-09589-9
PMCID:
PMC8989918
AbstractArticlePDF–2.5M
12.
PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders
José A. Manso, Tamara Marcos, Virginia Ruiz-Martín, Javier Casas, Pablo Alcón, Mariano Sánchez Crespo, Yolanda Bayón, José M. de Pereda, Andrés Alonso
Cell Mol Life Sci. 2022 Feb; 79(2): 131. Published online 2022 Feb 12. doi: 10.1007/s00018-022-04173-w
PMCID:
PMC8840930
AbstractArticlePDF–2.2M
13.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
14.
Recurrence of Graves’ Disease: What Genetics of HLA and PTPN22 Can Tell Us
Daniela Vejrazkova, Josef Vcelak, Eliska Vaclavikova, Marketa Vankova, Katerina Zajickova, Jana Vrbikova, Michaela Duskova, Petra Pacesova, Zdenek Novak, Bela Bendlova
Front Endocrinol (Lausanne) 2021; 12: 761077. Published online 2021 Nov 23. doi: 10.3389/fendo.2021.761077
PMCID:
PMC8650699
AbstractArticlePDF–324K
15.
Effect of PTPN22, FAS/FASL, IL2RA and CTLA4 genetic polymorphisms on the risk of developing alopecia areata: A systematic review of the literature and meta-analysis
S. R. Gil-Quiñones, I. T. Sepúlveda-Pachón, G. Sánchez Vanegas, L. D. Gutierrez-Castañeda
PLoS One. 2021; 16(11): e0258499. Published online 2021 Nov 4. doi: 10.1371/journal.pone.0258499
PMCID:
PMC8568157
AbstractArticlePDF–1.2M
16.
Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4+ T Cell Activation
Daniel J. Perry, Leeana D. Peters, Priya Saikumar Lakshmi, Lin Zhang, Zhao Han, Clive H. Wasserfall, Clayton E. Mathews, Mark A. Atkinson, Todd M. Brusko
J Immunol. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: J Immunol. 2021 Aug 1; 207(3): 849–859. Published online 2021 Jul 23. doi: 10.4049/jimmunol.2000708
PMCID:
PMC8323970
AbstractArticlePDF–1.5M
17.
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα
Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz
iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686
PMCID:
PMC8220391
AbstractArticlePDF–4.4M
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
Association of PTPN22-C1858T Polymorphism With Susceptibility to Mycobacterium tuberculosis and Mycobacterium leprae Infection: A Meta-Analysis
Shuping Li, Xiaohua Wang, Yuming Zhao, Juan Yang, Tianjiao Cui, Zhizhuang Joe Zhao, Yun Chen, Zhihua Zheng
Front Immunol. 2021; 12: 592841. Published online 2021 Feb 25. doi: 10.3389/fimmu.2021.592841
PMCID:
PMC7950544
AbstractArticlePDF–1.2M
20.
Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy
Rafael Cubas, Zia Khan, Qian Gong, Marina Moskalenko, Huizhong Xiong, Qinglin Ou, Christine Pai, Ryan Rodriguez, Jeanne Cheung, Andrew C Chan
J Immunother Cancer. 2020; 8(2): e001439. Published online 2020 Oct 30. doi: 10.1136/jitc-2020-001439
PMCID:
PMC7604869
AbstractArticlePDF–3.0M

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