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Items: 1 to 20 of 56

1.
Analysis of Pmel17/gp100 expression in primary human tissue specimens: implications for melanoma immuno- and gene-therapy
S. N. Wagner, Christine Wagner, Thomas Schultewolter, Manfred Goos
Cancer Immunol Immunother. 1997 Jun; 44(4): 239–247. doi: 10.1007/s002620050379
PMCID:
PMC11037831
AbstractArticlePDF–1.2M
2.
Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins
Paul W. Chrystal, Tim Footz, Elizabeth D. Hodges, Justin A. Jensen, Michael A. Walter, W. Ted Allison
Molecules. 2021 Jun; 26(12): 3529. Published online 2021 Jun 9. doi: 10.3390/molecules26123529
PMCID:
PMC8273697
AbstractArticlePDF–10M
3.
PMEL as a Prognostic Biomarker and Negatively Associated With Immune Infiltration in Skin Cutaneous Melanoma (SKCM)
Shuguang Zhang, Kun Chen, Huanmei Liu, Changyou Jing, Xinxin Zhang, Chunfeng Qu, Shengji Yu
J Immunother. 2021 Jul-Aug; 44(6): 214–223. Published online 2021 May 24. doi: 10.1097/CJI.0000000000000374
PMCID:
PMC8225232
AbstractArticlePDF–588K
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Identification of critical amino acid residues in the regulatory N-terminal domain of PMEL
Susan M. Mitchell, Morven Graham, Xinran Liu, Ralf M. Leonhardt
Sci Rep. 2021; 11: 7730. Published online 2021 Apr 8. doi: 10.1038/s41598-021-87259-y
PMCID:
PMC8032716
AbstractArticlePDF–6.9M
6.
Defining an amyloid link Between Parkinson’s disease and melanoma
Dexter N. Dean, Jennifer C. Lee
Proc Natl Acad Sci U S A. 2020 Sep 15; 117(37): 22671–22673. Published online 2020 Aug 31. doi: 10.1073/pnas.2009702117
PMCID:
PMC7502734
AbstractArticlePDF–1.0M
7.
Modulating functional amyloid formation via alternative splicing of the premelanosomal protein PMEL17
Dexter N. Dean, Jennifer C. Lee
J Biol Chem. 2020 May 22; 295(21): 7544–7553. Published online 2020 Apr 10. doi: 10.1074/jbc.RA120.013012
PMCID:
PMC7247297
AbstractArticlePDF–2.6M
8.
pH-Dependent Fibril Maturation of a Pmel17 Repeat Domain Isoform Revealed by Tryptophan Fluorescence
Dexter N. Dean, Jennifer C. Lee
Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2019 Oct; 1867(10): 961–969. Published online 2019 Feb 2. doi: 10.1016/j.bbapap.2019.01.012
PMCID:
PMC6700743
AbstractArticlePDF–2.0M
9.
Lysophospholipids induce Fibrillation of the Repeat domain of Pmel17 through intermediate core-shell structures
Jannik Nedergaard Pedersen, Zhiping Jiang, Gunna Christiansen, Jennifer C. Lee, Jan Skov Pedersen, Daniel E. Otzen
Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2019 May; 1867(5): 519–528. Published online 2018 Nov 22. doi: 10.1016/j.bbapap.2018.11.007
PMCID:
PMC6677129
ArticlePDF–2.0M
10.
Non-Synonymous variants in premelanosome protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma
Adrian A Lahola-Chomiak, Tim Footz, Kim Nguyen-Phuoc, Gavin J Neil, Baojian Fan, Keri F Allen, David S Greenfield, Richard K Parrish, Kevin Linkroum, Louis R Pasquale, Ralf M Leonhardt, Robert Ritch, Shari Javadiyan, Jamie E Craig, W T Allison, Ordan J Lehmann, Michael A Walter, Janey L Wiggs
Hum Mol Genet. 2019 Apr 15; 28(8): 1298–1311. Published online 2018 Dec 17. doi: 10.1093/hmg/ddy429
PMCID:
PMC6452206
AbstractArticlePDF–49M
11.
Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting
Clare Y. Slaney, Bianca von Scheidt, Alexander J. Davenport, Paul A. Beavis, Jennifer A. Westwood, Sherly Mardiana, David C. Tscharke, Sarah Ellis, H. Miles Prince, Joseph A. Trapani, Ricky W. Johnstone, Mark J. Smyth, Michele W. Teng, Aesha Ali, Zhiya Yu, Steven A. Rosenberg, Nicholas P. Restifo, Paul Neeson, Phillip K. Darcy, Michael H. Kershaw
Clin Cancer Res. Author manuscript; available in PMC 2019 Feb 11.
Published in final edited form as: Clin Cancer Res. 2017 May 15; 23(10): 2478–2490. Published online 2016 Dec 13. doi: 10.1158/1078-0432.CCR-16-1860
PMCID:
PMC6369535
AbstractArticlePDF–2.2M
12.
Insights into the ubiquitin-proteasome system of human embryonic stem cells
Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez
Sci Rep. 2018; 8: 4092. Published online 2018 Mar 6. doi: 10.1038/s41598-018-22384-9
PMCID:
PMC5840266
AbstractArticlePDF–2.9M
13.
Polyfunctional response by ImmTAC (IMCgp100) redirected CD8+ and CD4+ T cells
Caroline Boudousquie, Giovanna Bossi, Jacob M. Hurst, Karolina A. Rygiel, Bent K. Jakobsen, Namir J. Hassan
Immunology. 2017 Nov; 152(3): 425–438. Published online 2017 Aug 2. doi: 10.1111/imm.12779
PMCID:
PMC5629433
AbstractArticlePDF–1000K
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen
Valentina Bianchi, Anna Bulek, Anna Fuller, Angharad Lloyd, Meriem Attaf, Pierre J. Rizkallah, Garry Dolton, Andrew K. Sewell, David K. Cole
J Biol Chem. 2016 Apr 22; 291(17): 8951–8959. Published online 2016 Feb 25. doi: 10.1074/jbc.M115.707414
PMCID:
PMC4861463
AbstractArticlePDF–1.8M
16.
The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation
Tina Ho, Brenda Watt, Lynn A. Spruce, Steven H. Seeholzer, Michael S. Marks
J Biol Chem. 2016 Feb 12; 291(7): 3595–3612. Published online 2015 Dec 22. doi: 10.1074/jbc.M115.692442
PMCID:
PMC4751398
AbstractArticlePDF–3.3M
17.
The T210M Substitution in the HLA-a*02:01 gp100 Epitope Strongly Affects Overall Proteasomal Cleavage Site Usage and Antigen Processing
Kathrin Textoris-Taube, Christin Keller, Juliane Liepe, Petra Henklein, John Sidney, Alessandro Sette, Peter M. Kloetzel, Michele Mishto
J Biol Chem. 2015 Dec 18; 290(51): 30417–30428. Published online 2015 Oct 27. doi: 10.1074/jbc.M115.695189
PMCID:
PMC4683264
AbstractArticlePDF–2.0M
18.
Sorting of Pmel17 to melanosomes through the plasma membrane by AP1 and AP2: evidence for the polarized nature of melanocytes
Julio C. Valencia, Hidenori Watabe, An Chi, Francois Rouzaud, Kevin G. Chen, Wilfred D. Vieira, Kaoruko Takahashi, Yuji Yamaguchi, Werner Berens, Kunio Nagashima, Jeffrey Shabanowitz, Donald F. Hunt, Ettore Appella, Vincent J. Hearing
J Cell Sci. Author manuscript; available in PMC 2015 Nov 2.
Published in final edited form as: J Cell Sci. 2006 Mar 15; 119(0 6): 1080–1091. Published online 2006 Feb 21. doi: 10.1242/jcs.02804
PMCID:
PMC4629779
AbstractArticlePDF–1.2M
19.
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
Tomomitsu Hirota, Atsushi Takahashi, Michiaki Kubo, Tatsuhiko Tsunoda, Kaori Tomita, Satoru Doi, Kimie Fujita, Akihiko Miyatake, Tadao Enomoto, Takehiko Miyagawa, Mitsuru Adachi, Hiroshi Tanaka, Akio Niimi, Hisako Matsumoto, Isao Ito, Hironori Masuko, Tohru Sakamoto, Nobuyuki Hizawa, Masami Taniguchi, John J. Lima, Charles G. Irvin, Stephen P. Peters, Blanca E. Himes, Augusto A. Litonjua, Kelan G. Tantisira, Scott T. Weiss, Naoyuki Kamatani, Yusuke Nakamura, Mayumi Tamari
Nat Genet. Author manuscript; available in PMC 2015 Jan 29.
Published in final edited form as: Nat Genet. 2011 Sep; 43(9): 893–896. Published online 2011 Jul 31. doi: 10.1038/ng.887
PMCID:
PMC4310726
ArticlePDF–376K
20.
Lysophospholipid-containing Membranes Modulate the Fibril Formation of the Repeat Domain of a Human Functional Amyloid, Pmel17
Zhiping Jiang, Jennifer C. Lee
J Mol Biol. Author manuscript; available in PMC 2015 Dec 12.
Published in final edited form as: J Mol Biol. 2014 Dec 12; 426(24): 4074–4086. Published online 2014 Oct 14. doi: 10.1016/j.jmb.2014.10.009
PMCID:
PMC4258903
AbstractArticlePDF–2.7M

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