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Items: 1 to 20 of 91

1.
Association of the neonatal Fc receptor promoter variable number of tandem repeat polymorphism with immunoglobulin response in patients with chronic inflammatory demyelinating polyneuropathy
Anna Lena Fisse, Emelie Schäfer, Alina Hieke, Maximilian Schröder, Rafael Klimas, Jil Brünger, Sophie Huckemann, Thomas Grüter, Melissa Sgodzai, Christiane Schneider‐Gold, Ralf Gold, Huu Phuc Nguyen, Kalliopi Pitarokoili, Jeremias Motte, Larissa Arning
Eur J Neurol. 2024 Apr; 31(4): e16205. Published online 2024 Jan 11. doi: 10.1111/ene.16205
PMCID:
PMC11235998
AbstractArticlePDF–470K
2.
Albumin influences leucocyte FcRn expression in the early days of kidney transplantation
Pierre Boulard, Nicolas Azzopardi, Romain Levard, Jean-Marie Cornec, Juliette Lamamy, Bérénice Prieur, Marie-Véronique Demattei, Hervé Watier, Philippe Gatault, Valérie Gouilleux-Gruart
Clin Exp Immunol. 2024 Jun; 216(3): 307–317. Published online 2024 Feb 12. doi: 10.1093/cei/uxae011
PMCID:
PMC11097912
AbstractArticlePDF–2.3M
3.
The therapeutic age of the neonatal Fc receptor
Michal Pyzik, Lisa K. Kozicky, Amit K. Gandhi, Richard S. Blumberg
Nat Rev Immunol. 2023 Feb 1 : 1–18. doi: 10.1038/s41577-022-00821-1 [Epub ahead of print]
PMCID:
PMC9891766
AbstractArticlePDF–4.9M
4.
Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18
Xiangpeng Chen, Xiao Qu, Congcong Liu, Yong Zhang, Guigen Zhang, Pu Han, Yali Duan, Qi Li, Liang Wang, Wenjing Ruan, Peiyi Wang, Wensheng Wei, George F. Gao, Xin Zhao, Zhengde Xie
mBio. 2022 Jul-Aug; 13(4): e01166-22. Published online 2022 Jul 5. doi: 10.1128/mbio.01166-22
PMCID:
PMC9426509
AbstractArticlePDF–3.5M
5.
An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript
Fernando Riveros-Mckay, David Roberts, Emanuele Di Angelantonio, Bing Yu, Nicole Soranzo, John Danesh, Elizabeth Selvin, Adam S. Butterworth, Inês Barroso
Diabetes. 2022 Feb; 71(2): 359–364. Published online 2021 Nov 9. doi: 10.2337/db21-0320
PMCID:
PMC8914280
AbstractArticlePDF–1.1M
6.
Human IgE does not bind to human FcRn
Maximilian Brinkhaus, Elvera J. van der Kooi, Arthur E. H. Bentlage, Pleuni Ooijevaar-de Heer, Ninotska I. L. Derksen, Theo Rispens, Gestur Vidarsson
Sci Rep. 2022; 12: 62. Published online 2022 Jan 7. doi: 10.1038/s41598-021-03852-1
PMCID:
PMC8741920
AbstractArticlePDF–2.1M
7.
新生儿 Fc受体基础研究和临床应用进展
Mangsha HU, Shuli WEI, Wuyuan ZHOU, Pingli WANG
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2021 Aug; 50(4): 537–544. Chinese. doi: 10.3724/zdxbyxb-2021-0252
PMCID:
PMC8714478
AbstractArticlePDF–2.7M
8.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice
Benjamin E. Low, Gregory J. Christianson, Emily Lowell, Wenning Qin, Michael V. Wiles
MAbs. 2020 Jan-Dec; 12(1): 1829334. Published online 2020 Oct 7. doi: 10.1080/19420862.2020.1829334
PMCID:
PMC7577234
AbstractArticlePDF–2.3M
11.
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex–driven autoimmunity
Jonathan J. Hubbard, Michal Pyzik, Timo Rath, Lisa K. Kozicky, Kine M.K. Sand, Amit K. Gandhi, Algirdas Grevys, Stian Foss, Susan C. Menzies, Jonathan N. Glickman, Edda Fiebiger, Derry C. Roopenian, Inger Sandlie, Jan Terje Andersen, Laura M. Sly, Kristi Baker, Richard S. Blumberg
J Exp Med. 2020 Oct 5; 217(10): e20200359. Published online 2020 Jul 13. doi: 10.1084/jem.20200359
PMCID:
PMC7537387
AbstractArticlePDF–3.4M
12.
FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies
Sara Borghi, Stylianos Bournazos, Natalie K. Thulin, Chao Li, Anna Gajewski, Robert W. Sherwood, Sheng Zhang, Eva Harris, Prasanna Jagannathan, Lai-Xi Wang, Jeffrey V. Ravetch, Taia T. Wang
Proc Natl Acad Sci U S A. 2020 Jun 9; 117(23): 12943–12951. Published online 2020 May 27. doi: 10.1073/pnas.2004325117
PMCID:
PMC7293622
AbstractArticlePDF–1.2M
13.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
14.
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057
PMCID:
PMC6831851
AbstractArticlePDF–9.8M
15.
Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor
Xiaoyang Liu, Senthilkumar Palaniyandi, Iowis Zhu, Jin Tang, Weizhong Li, Xiaoling Wu, Susan Park Ochsner, C. David Pauza, Jeffrey I. Cohen, Xiaoping Zhu
Nat Commun. 2019; 10: 3020. Published online 2019 Jul 9. doi: 10.1038/s41467-019-10865-y
PMCID:
PMC6617459
AbstractArticlePDF–4.4M
16.
Contribution of DNA methylation to the expression of FCGRT in human liver and myocardium
R. B. Cejas, D. C. Ferguson, A. Quiñones-Lombraña, J. E. Bard, J. G. Blanco
Sci Rep. 2019; 9: 8674. Published online 2019 Jun 17. doi: 10.1038/s41598-019-45203-1
PMCID:
PMC6572836
AbstractArticlePDF–2.8M
17.
Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge
Nigel M. Stapleton, Maximilian Brinkhaus, Kathryn L. Armour, Arthur E. H. Bentlage, Steven W. de Taeye, A. Robin Temming, Juk Yee Mok, Giso Brasser, Marielle Maas, Wim J. E. van Esch, Mike R. Clark, Lorna M. Williamson, C. Ellen van der Schoot, Gestur Vidarsson
Sci Rep. 2019; 9: 7363. Published online 2019 May 14. doi: 10.1038/s41598-019-40731-2
PMCID:
PMC6517591
AbstractArticlePDF–1.5M
18.
FcRn-Dependent Transcytosis of Monoclonal Antibody in Human Nasal Epithelial Cells In Vitro: A Prerequisite for a New Delivery Route for Therapy?
Emilie Bequignon, Christine Dhommée, Christelle Angely, Lucie Thomas, Mathieu Bottier, Estelle Escudier, Daniel Isabey, André Coste, Bruno Louis, Jean-François Papon, Valérie Gouilleux-Gruart
Int J Mol Sci. 2019 Mar; 20(6): 1379. Published online 2019 Mar 19. doi: 10.3390/ijms20061379
PMCID:
PMC6470570
AbstractArticlePDF–5.0M
19.
The neonatal Fc receptor is a pan-echovirus receptor
Stefanie Morosky, Alexandra I. Wells, Kathryn Lemon, Azia S. Evans, Sandra Schamus, Christopher J. Bakkenist, Carolyn B. Coyne
Proc Natl Acad Sci U S A. 2019 Feb 26; 116(9): 3758–3763. Published online 2019 Feb 11. doi: 10.1073/pnas.1817341116
PMCID:
PMC6397586
AbstractArticlePDF–1.3M
20.
FcRn Expression in Wildtype Mice, Transgenic Mice, and in Human Tissues
Tommy Li, Joseph P. Balthasar
Biomolecules. 2018 Dec; 8(4): 115. Published online 2018 Oct 15. doi: 10.3390/biom8040115
PMCID:
PMC6316262
AbstractArticlePDF–1.9M

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