PMC Links for GEO Profiles (Select 132112296) - PMC

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76458635.

N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

Tomas Koudelka, Juliane Boger, Alessandra Henkel, Robert Schönherr, Stefanie Krantz, Sabine Fuchs, Estefanía Rodríguez, Lars Redecke, Andreas Tholey

Proteomics. 2021 Jan; 21(2): 2000246. Published online 2020 Nov 17. doi: 10.1002/pmic.202000246

PMCID:: PMC7645863

Abstract Article PDF–497K

Select item 67260696.

Parkin Mediates Nonclassical, Proteasomal-Independent Ubiquitination of Synphilin-1: Implications for Lewy Body Formation

Kah Leong Lim, Katherine C. M. Chew, Jeanne M. M. Tan, Cheng Wang, Kenny K. K. Chung, Yi Zhang, Yuji Tanaka, Wanli Smith, Simone Engelender, Christopher A. Ross, Valina L. Dawson, Ted M. Dawson

J Neurosci. 2005 Feb 23; 25(8): 2002–2009. doi: 10.1523/JNEUROSCI.4474-04.2005

PMCID:: PMC6726069

Abstract Article PDF–360K

Select item 67249827.

α-Synuclein Phosphorylation Enhances Eosinophilic Cytoplasmic Inclusion Formation in SH-SY5Y Cells

Wanli W. Smith, Russell L. Margolis, Xiaojie Li, Juan C. Troncoso, Michael K. Lee, Valina L. Dawson, Ted M. Dawson, Takashi Iwatsubo, Christopher A. Ross

J Neurosci. 2005 Jun 8; 25(23): 5544–5552. doi: 10.1523/JNEUROSCI.0482-05.2005

PMCID:: PMC6724982

Abstract Article PDF–606K

Select item 64241178.

Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity

Xueping Li, Zhaohui Liu, Kellie Tamashiro, Bingyin Shi, Dobrila D. Rudnicki, Christopher A. Ross, Timothy H. Moran, Wanli W. Smith

Neuroscience. Author manuscript; available in PMC 2019 Mar 19.

Published in final edited form as: Neuroscience. 2010 Jan 20; 165(2): 455–462. doi: 10.1016/j.neuroscience.2009.10.042

PMCID:: PMC6424117

Abstract Article PDF–670K

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 461721110.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 450276011.

Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment

Anne-Maria Poehler, Wei Xiang, Philipp Spitzer, Verena Elisabeth Luise May, Holger Meixner, Edward Rockenstein, Oldriska Chutna, Tiago Fleming Outeiro, Juergen Winkler, Eliezer Masliah, Jochen Klucken

Autophagy. 2014 Dec; 10(12): 2171–2192. Published online 2015 Jan 28. doi: 10.4161/auto.36436

PMCID:: PMC4502760

Abstract Article PDF–2.9M

Select item 445992112.

α-Synuclein binds the K_ATP channel at insulin-secretory granules and inhibits insulin secretion

Xuehui Geng, Haiyan Lou, Jian Wang, Lehong Li, Alexandra L. Swanson, Ming Sun, Donna Beers-Stolz, Simon Watkins, Ruth G. Perez, Peter Drain

Am J Physiol Endocrinol Metab. 2011 Feb; 300(2): E276–E286. Published online 2010 Sep 21. doi: 10.1152/ajpendo.00262.2010

PMCID:: PMC4459921

Abstract Article

Select item 444796113.

Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling

Kristi L. Norris, Rui Hao, Liang-Fu Chen, Chun-Hsiang Lai, Meghan Kapur, Peter J. Shaughnessy, Dennis Chou, Jin Yan, J. Paul Taylor, Simone Engelender, Anna E. West, Kah-Leong Lim, Tso-Pang Yao

J Biol Chem. 2015 May 29; 290(22): 13862–13874. Published online 2015 Apr 10. doi: 10.1074/jbc.M114.634063

PMCID:: PMC4447961

Abstract Article PDF–4.3M

Select item 427885714.

Synphilin-1 Binds ATP and Regulates Intracellular Energy Status

Tianxia Li, Jingnan Liu, Wanli W. Smith

PLoS One. 2014; 9(12): e115233. Published online 2014 Dec 29. doi: 10.1371/journal.pone.0115233

PMCID:: PMC4278857

Abstract Article PDF–1.0M

Select item 422714815.

GRP78 clustering at the cell surface of neurons transduces the action of exogenous alpha-synuclein

S Bellani, A Mescola, G Ronzitti, H Tsushima, S Tilve, C Canale, F Valtorta, E Chieregatti

Cell Death Differ. 2014 Dec; 21(12): 1971–1983. Published online 2014 Aug 15. doi: 10.1038/cdd.2014.111

PMCID:: PMC4227148

Abstract Article PDF–4.1M

Select item 419909016.

α-Synuclein and Mitochondrial Dysfunction in Parkinson’s Disease

Stephen Mullin, Anthony Schapira

Mol Neurobiol. Author manuscript; available in PMC 2014 Oct 16.

Published in final edited form as: Mol Neurobiol. 2013 Apr; 47(2): 587–597. Published online 2013 Jan 30. doi: 10.1007/s12035-013-8394-x

PMCID:: PMC4199090

Abstract Article PDF–342K

Select item 402074217.

Behavioral Characterization of the Hyperphagia Synphilin-1 Overexpressing Mice

Xueping Li, Yada Treesukosol, Alexander Moghadam, Megan Smith, Erica Ofeldt, Dejun Yang, Tianxia Li, Kellie Tamashiro, Pique Choi, Timothy H. Moran, Wanli W. Smith

PLoS One. 2014; 9(5): e91449. Published online 2014 May 14. doi: 10.1371/journal.pone.0091449

PMCID:: PMC4020742

Abstract Article PDF–875K

Select item 371508618.

Synphilin-1 alters metabolic homeostasis in a novel Drosophila obesity model

J Liu, T Li, D Yang, R Ma, TH Moran, WW Smith

Int J Obes (Lond) Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Int J Obes (Lond). 2012 Dec; 36(12): 1529–1536. Published online 2012 Jul 17. doi: 10.1038/ijo.2012.111

Correction in:: volume 36 on page 1592

PMCID:: PMC3715086

Abstract Article PDF–2.9M

Select item 355232619.

Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity

Thai Leong Yap, Arash Velayati, Ellen Sidransky, Jennifer C. Lee

Mol Genet Metab. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Mol Genet Metab. 2013 Jan; 108(1): 56–64. Published online 2012 Nov 28. doi: 10.1016/j.ymgme.2012.11.010

PMCID:: PMC3552326

Abstract Article PDF–1.7M

Select item 352739120.

The Guanine Nucleotide Exchange Factor Kalirin-7 Is a Novel Synphilin-1 Interacting Protein and Modifies Synphilin-1 Aggregate Transport and Formation

Yu-Chun Tsai, Olaf Riess, Anne S. Soehn, Huu Phuc Nguyen

PLoS One. 2012; 7(12): e51999. Published online 2012 Dec 20. doi: 10.1371/journal.pone.0051999

PMCID:: PMC3527391

Abstract Article PDF–5.8M

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