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Items: 1 to 20 of 41

1.
Mechanism of ELL-associated factor 2 and vasohibin 1 regulating invasion, migration, and angiogenesis in colorectal cancer
Ming-Liang Feng, Ming-Jun Sun, Bo-Yang Xu, Meng-Yuan Liu, Hui-Jing Zhang, Can Wu
World J Gastroenterol. 2023 Jun 28; 29(24): 3770–3792. Published online 2023 Jun 28. doi: 10.3748/wjg.v29.i24.3770
PMCID:
PMC10324531
AbstractArticlePDF–26M
2.
Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions
Subham Basu, Arijit Nandy, Mahesh K. Barad, Sujay Pal, Debabrata Biswas
Mol Cell Biol. 2022 Oct; 42(10): e00151-22. Published online 2022 Aug 29. doi: 10.1128/mcb.00151-22
PMCID:
PMC9590304
AbstractArticlePDF–3.2M
3.
CircEAF2 counteracts Epstein-Barr virus-positive diffuse large B-cell lymphoma progression via miR-BART19-3p/APC/β-catenin axis
Chen-xing Zhao, Zi-xun Yan, Jing-jing Wen, Di Fu, Peng-peng Xu, Li Wang, Shu Cheng, Jian-da Hu, Wei-li Zhao
Mol Cancer. 2021; 20: 153. Published online 2021 Dec 1. doi: 10.1186/s12943-021-01458-9
PMCID:
PMC8638185
AbstractArticlePDF–4.1M
4.
Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation
Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee
Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572
PMCID:
PMC8307194
AbstractArticlePDF–2.8M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9
PMCID:
PMC7910459
AbstractArticlePDF–3.3M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
DBC1, p300, HDAC3, and Siah1 coordinately regulate ELL stability and function for expression of its target genes
Subham Basu, Mahesh Barad, Dipika Yadav, Arijit Nandy, Bidisha Mukherjee, Jit Sarkar, Partha Chakrabarti, Satinath Mukhopadhyay, Debabrata Biswas
Proc Natl Acad Sci U S A. 2020 Mar 24; 117(12): 6509–6520. Published online 2020 Mar 9. doi: 10.1073/pnas.1912375117
PMCID:
PMC7104407
AbstractArticlePDF–2.5M
9.
Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells
Tiejun Yang, Yifeng Jing, Jun Dong, Xinpei Yu, Mingming Zhong, Laura E. Pascal, Dan Wang, Zhongxian Zhang, Baoping Qiao, Zhou Wang
Prostate. Author manuscript; available in PMC 2019 May 28.
Published in final edited form as: Prostate. 2018 Nov; 78(15): 1201–1212. Published online 2018 Jul 15. doi: 10.1002/pros.23695
Correction in:
Prostate. 2020 Feb; 80(2): 238.
PMCID:
PMC6537586
AbstractArticlePDF–1.5M
10.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
11.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
12.
EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer
Laura E. Pascal, Yao Wang, Mingming Zhong, Dan Wang, Anish Bhaswanth Chakka, Zhenyu Yang, Feng Li, Qiong Song, Lora H. Rigatti, Srilakshmi Chaparala, Uma Chandran, Anil V. Parwani, Zhou Wang
Neoplasia. 2018 Apr; 20(4): 351–363. Published online 2018 Mar 6. doi: 10.1016/j.neo.2018.01.011
PMCID:
PMC5909677
AbstractArticlePDF–2.9M
13.
Eaf2 protects human lens epithelial cells against oxidative stress-induced apoptosis by Wnt signaling
Ke Feng, Hai-Ke Guo
Mol Med Rep. 2018 Feb; 17(2): 2795–2802. Published online 2017 Dec 11. doi: 10.3892/mmr.2017.8246
PMCID:
PMC5783493
AbstractArticlePDF–3.0M
14.
Combined Loss of EAF2 and p53 Induces Prostate Carcinogenesis in Male Mice
Yao Wang, Laura E. Pascal, Mingming Zhong, Junkui Ai, Dan Wang, Yifeng Jing, Jan Pilch, Qiong Song, Lora H. Rigatti, Lara E. Graham, Joel B. Nelson, Anil V. Parwani, Zhou Wang
Endocrinology. 2017 Dec 1; 158(12): 4189–4205. Published online 2017 Sep 27. doi: 10.1210/en.2017-00409
PMCID:
PMC5711381
AbstractArticle
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
EAF2 regulates DNA repair through Ku70/Ku80 in the prostate
J Ai, L E Pascal, L Wei, Y Zang, Y Zhou, X Yu, Y Gong, S Nakajima, J B Nelson, A S Levine, L Lan, Z Wang
Oncogene. 2017 Apr; 36(15): 2054–2065. Published online 2016 Oct 10. doi: 10.1038/onc.2016.373
PMCID:
PMC5386836
AbstractArticlePDF–3.5M
17.
EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling
Bo Pang, Xiang-Rong Zheng, Jing-xia Tian, Tai-hong Gao, Guang-yan Gu, Rui Zhang, Yi-Bing Fu, Qi Pang, Xin-Gang Li, Qian Liu
Oncotarget. 2016 Jul 19; 7(29): 45134–45143. Published online 2016 Jun 1. doi: 10.18632/oncotarget.9761
PMCID:
PMC5216711
AbstractArticlePDF–7.2M
18.
Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells
Xinpei Yu, Junkui Ai, Liquan Cai, Yifeng Jing, Dan Wang, Jun Dong, Laura E. Pascal, Jian Zhang, Rongcheng Luo, Zhou Wang
Oncotarget. 2016 May 17; 7(20): 29245–29254. Published online 2016 Apr 5. doi: 10.18632/oncotarget.8588
Correction in:
Oncotarget. 2019 Dec 24; 10(67): 7181–7182.
PMCID:
PMC5045393
AbstractArticlePDF–5.3M
19.
Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal
Li Du, Yi-Jia Li, Marwan Fakih, Rebecca L. Wiatrek, Marjun Duldulao, Zhenbin Chen, Peiguo Chu, Julio Garcia-Aguilar, Yuan Chen
Nat Commun. 2016; 7: 12326. Published online 2016 Jul 28. doi: 10.1038/ncomms12326
PMCID:
PMC4974481
AbstractArticlePDF–1.5M
20.
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth
Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660
PMCID:
PMC4848762
AbstractArticlePDF–2.8M

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