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Select item 111566441.

ATF4 inhibits tumor development and mediates p-GCN2/ASNS upregulation in colon cancer

Jiawei Chen, Xiaopeng Huang, Shuai Zhang, Xiaodong Zhu

Sci Rep. 2024; 14: 13042. Published online 2024 Jun 6. doi: 10.1038/s41598-024-63895-y

PMCID:: PMC11156644

Abstract Article PDF–3.9M

Select item 110584732.

Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control

Anna M. Smirnova, Vladislava Hronová, Mahabub Pasha Mohammad, Anna Herrmannová, Stanislava Gunišová, Denisa Petráčková, Petr Halada, Štěpán Coufal, Michał Świrski, Justin Rendleman, Kristína Jendruchová, Maria Hatzoglou, Petra Beznosková, Christine Vogel, Leoš Shivaya Valášek

Cell Rep. Author manuscript; available in PMC 2024 Apr 30.

Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 113976. Published online 2024 Mar 19. doi: 10.1016/j.celrep.2024.113976

PMCID:: PMC11058473

Abstract Article PDF–2.1M

Select item 110209813.

miR-214 aggravates oxidative stress in thalassemic erythroid cells by targeting ATF4

Tipparat Penglong, Apisara Saensuwanna, Husanai Jantapaso, Pongpon Phuwakanjana, Natee Jearawiriyapaisarn, Kittiphong Paiboonsukwong, Worrawit Wanichsuwan, Kanitta Srinoun

PLoS One. 2024; 19(4): e0300958. Published online 2024 Apr 16. doi: 10.1371/journal.pone.0300958

PMCID:: PMC11020981

Abstract Article PDF–2.1M

Select item 109850794.

Advanced glycation end products promote meniscal calcification by activating the mTOR-ATF4 positive feedback loop

Sheng Yang, JiaJun Xie, ZhiJie Pan, HongMei Guan, YueSheng Tu, YuanJian Ye, ShouBin Huang, ShiQiang Fu, KangXian Li, ZhiWei Huang, XiaoQi Li, ZhanJun Shi, Le Li, Yang Zhang

Exp Mol Med. 2024 Mar; 56(3): 630–645. Published online 2024 Mar 1. doi: 10.1038/s12276-024-01190-6

PMCID:: PMC10985079

Abstract Article PDF–8.4M

Select item 106377235.

Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs

Tiit Örd, Daima Örd, Priit Adler, Tõnis Örd

PLoS Genet. 2023 Oct; 19(10): e1011014. Published online 2023 Oct 31. doi: 10.1371/journal.pgen.1011014

PMCID:: PMC10637723

Abstract Article PDF–3.2M

Select item 97896866.

Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

Meng Li, Matthew R. Teater, Jun Young Hong, Noel R. Park, Cihangir Duy, Hao Shen, Ling Wang, Zhengming Chen, Leandro Cerchietti, Shawn M. Davidson, Hening Lin, Ari M. Melnick

Blood Cancer Discov. 2022 Jan; 3(1): 50–65. Published online 2021 Nov 9. doi: 10.1158/2643-3230.BCD-20-0183

PMCID:: PMC9789686

Abstract Article PDF–7.6M

Select item 97789457.

TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF

Lan Wang, Wenyu Zhao, Cong Xia, Zhongzheng Li, Weiming Zhao, Kai Xu, Ningdan Wang, Hui Lian, Ivan O. Rosas, Guoying Yu

Int J Mol Sci. 2022 Dec; 23(24): 15705. Published online 2022 Dec 11. doi: 10.3390/ijms232415705

PMCID:: PMC9778945

Abstract Article PDF–4.1M

Select item 97494648.

Upregulation of ATF4-LAMP3 Axis by ORF45 Facilitates Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus

Qinqin Sun, Fan Wang, Qingyang Chen, Ronit Sarid, Xiaojuan Li, Ersheng Kuang

J Virol. 2022 Dec; 96(23): e01456-22. Published online 2022 Nov 15. doi: 10.1128/jvi.01456-22

PMCID:: PMC9749464

Abstract Article PDF–3.8M

Select item 97138609.

Activating transcription factor 4 regulates hypoxia inducible factor 1α in chronic hypoxia in pancreatic cancer cells

Nancy T. Chee, Candace H. Carriere, Zachary Miller, Scott Welford, Shaun P. Brothers

Oncol Rep. 2023 Jan; 49(1): 14. Published online 2022 Nov 23. doi: 10.3892/or.2022.8451

PMCID:: PMC9713860

Abstract Article PDF–1.8M

Select item 957386510.

ATF4-dependent fructolysis fuels growth of glioblastoma multiforme

Chao Chen, Zhenxing Zhang, Caiyun Liu, Bin Wang, Ping Liu, Shu Fang, Fan Yang, Yongping You, Xinjian Li

Nat Commun. 2022; 13: 6108. Published online 2022 Oct 16. doi: 10.1038/s41467-022-33859-9

PMCID:: PMC9573865

Abstract Article PDF–3.1M

Select item 942510711.

ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis

Yixing Gao, Lan Feng, Luping Zhang, Jianhui Geng, Erlong Zhang

Dis Markers. 2022; 2022: 7527996. Published online 2022 Aug 22. doi: 10.1155/2022/7527996

PMCID:: PMC9425107

Abstract Article PDF–2.2M

Select item 937520012.

uORF-Mediated Translational Regulation of ATF4 Serves as an Evolutionarily Conserved Mechanism Contributing to Non-Small-Cell Lung Cancer (NSCLC) and Stress Response

Wenjing Xiao, Yang Sun, Jinpeng Xu, Na Zhang, Lina Dong

J Mol Evol. 2022; 90(5): 375–388. Published online 2022 Aug 13. doi: 10.1007/s00239-022-10068-y

PMCID:: PMC9375200

Abstract Article PDF–2.0M

Select item 932466413.

Gremlin-1 Promotes Colorectal Cancer Cell Metastasis by Activating ATF6 and Inhibiting ATF4 Pathways

Ruohan Li, Huaixiang Zhou, Mingzhe Li, Qiuyan Mai, Zhang Fu, Youheng Jiang, Changxue Li, Yunfei Gao, Yunping Fan, Kaiming Wu, Clive Da Costa, Xia Sheng, Yulong He, Ningning Li

Cells. 2022 Jul; 11(14): 2136. Published online 2022 Jul 7. doi: 10.3390/cells11142136

PMCID:: PMC9324664

Abstract Article PDF–14M

Select item 929931414.

ATF4 promotes brain vascular smooth muscle cells proliferation, invasion and migration by targeting miR-552-SKI axis

Meina Feng, Qin Zhou, Wenxian Tu, Yunfeng Wang, Yuanmin Du, Kang Xu

PLoS One. 2022; 17(7): e0270880. Published online 2022 Jul 20. doi: 10.1371/journal.pone.0270880

PMCID:: PMC9299314

Abstract Article PDF–3.6M

Select item 923009315.

Induction of DR5-Dependent Apoptosis by PGA₂ through ATF4-CHOP Pathway

Kyeong-Min Park, Ji-Young Park, Jaehyuk Pyo, Sun-Young Lee, Ho-Shik Kim

Molecules. 2022 Jun; 27(12): 3804. Published online 2022 Jun 13. doi: 10.3390/molecules27123804

PMCID:: PMC9230093

Abstract Article PDF–1.4M

Select item 912665916.

Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis

Lulu Guan, Feifei Wang, Mengjiao Wang, Songfeng Han, Zhaohai Cui, Shoumin Xi, Haixu Xu, Shipeng Li

Oxid Med Cell Longev. 2022; 2022: 9613095. Published online 2022 May 16. doi: 10.1155/2022/9613095

PMCID:: PMC9126659

Abstract Article PDF–2.9M

Select item 893370317.

PRMT5 regulates ATF4 transcript splicing and oxidative stress response

Magdalena M. Szewczyk, Genna M. Luciani, Victoria Vu, Alex Murison, David Dilworth, Samir H. Barghout, Mathieu Lupien, Cheryl H. Arrowsmith, Mark D. Minden, Dalia Barsyte-Lovejoy

Redox Biol. 2022 May; 51: 102282. Published online 2022 Mar 11. doi: 10.1016/j.redox.2022.102282

PMCID:: PMC8933703

Abstract Article PDF–8.9M

Select item 875821718.

Mini review ATF4 and GRP78 as novel molecular targets in ER-Stress modulation for critical COVID-19 patients

Mahtab Shahriari-Felordi, Hani Keshavarz Alikhani, Seyed-Mohammad Reza Hashemian, Moustapha Hassan, Massoud Vosough

Mol Biol Rep. 2022; 49(2): 1545–1549. Published online 2022 Jan 14. doi: 10.1007/s11033-021-07071-9

PMCID:: PMC8758217

Abstract Article PDF–885K

Select item 874868819.

ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells

Ying Yu, Bing Liu, Xuexiang Li, Dingheng Lu, Likun Yang, Liang Chen, Yunxue Li, Lulin Cheng, Fang Lv, Pu Zhang, Yarong Song, Yifei Xing

Cell Death Dis. 2022 Jan; 13(1): 46. Published online 2022 Jan 10. doi: 10.1038/s41419-021-04494-x

PMCID:: PMC8748688

Abstract Article PDF–6.0M

Select item 867572720.

Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a

Christopher J. Fields, Lu Li, Nicholas M. Hiers, Tianqi Li, Peike Sheng, Taha Huda, Jixiu Shan, Lauren Gay, Tongjun Gu, Jiang Bian, Michael S. Kilberg, Rolf Renne, Mingyi Xie

PLoS Genet. 2021 Dec; 17(12): e1009934. Published online 2021 Dec 16. doi: 10.1371/journal.pgen.1009934

PMCID:: PMC8675727

Abstract Article PDF–1.5M

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