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Select item 115275281.

Genetic Variations in AMPK, FOXO3A, and POMC Increase the Risk of Extreme Obesity

Cinthia Vila Nova Santana, Luiz Alexandre Viana Magno, Adauto Versiani Ramos, Maria Angélica Rios, Valéria Cristina Sandrim, Luiz Armando De Marco, Débora Marques de Miranda, Marco Aurélio Romano-Silva

J Obes. 2024; 2024: 3813621. Published online 2024 Oct 24. doi: 10.1155/2024/3813621

PMCID:: PMC11527528

Abstract Article PDF–433K

Select item 109106262.

Fluctuations in plasma adrenocorticotropic hormone concentration may predict the onset of immune checkpoint inhibitor-related hypophysitis

Hironori Bando, Masaaki Yamamoto, Shin Urai, Yuma Motomura, Yuriko Sasaki, Yuka Ohmachi, Masaki Kobatake, Yasutaka Tsujimoto, Yuka Oi-Yo, Masaki Suzuki, Naoki Yamamoto, Michiko Takahashi, Hidenori Fukuoka, Genzo Iguchi, Wataru Ogawa

J Immunother Cancer. 2024; 12(2): e008634. Published online 2024 Feb 28. doi: 10.1136/jitc-2023-008634

Correction in:: J Immunother Cancer. 2024; 12(3): e008634corr1.

PMCID:: PMC10910626

Abstract Article PDF–676K

Select item 104633883.

Alpha-melanocyte stimulating hormone (α-MSH): biology, clinical relevance and implication in melanoma

Luigi Dall’Olmo, Nicole Papa, Nicoletta Concetta Surdo, Ilaria Marigo, Simone Mocellin

J Transl Med. 2023; 21: 562. Published online 2023 Aug 22. doi: 10.1186/s12967-023-04405-y

PMCID:: PMC10463388

Abstract Article PDF–856K

Select item 103110854.

Maternal glucose intolerance during pregnancy affects offspring POMC expression and results in adult metabolic alterations in a sex-dependent manner

Marina Galleazzo Martins, Zachary Silver, Kiara Ayoub, Lindsay Hyland, Barbara Woodside, Ana Carolina Inhasz Kiss, Alfonso Abizaid

Front Endocrinol (Lausanne) 2023; 14: 1189207. Published online 2023 Jun 15. doi: 10.3389/fendo.2023.1189207

PMCID:: PMC10311085

Abstract Article PDF–6.4M

Select item 97970395.

Obesity and Hyperphagia With Increased Defective ACTH: A Novel POMC Variant

Eline S van der Valk, Lotte Kleinendorst, Patric J D Delhanty, Bibian van der Voorn, Jenny A Visser, M M van Haelst, Laura C G de Graaff, Martin Huisman, Anne White, Shosuke Ito, Kazumasa Wakamatsu, Yolanda B de Rijke, Erica L T van den Akker, Anand M Iyer, Elisabeth F C van Rossum

J Clin Endocrinol Metab. 2022 Sep; 107(9): e3699–e3704. Published online 2022 Jun 23. doi: 10.1210/clinem/dgac342

PMCID:: PMC9797039

Abstract Article

Select item 96644686.

Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice

Ilaria Coppola, Bas Brouwers, Leanne Walker, Ceyhun Alar, Sandra Meulemans, Anne White, Bruno Ramos-Molina, John W.M. Creemers

Mol Metab. 2022 Dec; 66: 101627. Published online 2022 Oct 29. doi: 10.1016/j.molmet.2022.101627

PMCID:: PMC9664468

Abstract Article PDF–1.4M

Select item 93828447.

Gene expression and methylation profiles show the involvement of POMC in primary hyperparathyroidsm

Wen-Xuan Zhou, Shu Wang, Ting-Chao Wu, Ling-Chao Cheng, Yao Du, Wei Wu, Chen Lin, Xin-Ying Li, Zhong-Liang Hu

J Transl Med. 2022; 20: 368. Published online 2022 Aug 16. doi: 10.1186/s12967-022-03568-4

PMCID:: PMC9382844

Abstract Article PDF–3.1M

Select item 92489148.

Single Cell RNA Sequencing in Silent Corticotroph Tumors Confirms Impaired POMC Processing and Provides New Insights into Their Invasive Behavior

Dongyun Zhang, Willy Hugo, Marvin Bergsneider, Marilene B. Wang, Won Kim, Harry V. Vinters, Anthony P. Heaney

Eur J Endocrinol. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Eur J Endocrinol. 2022 May 12; 187(1): 49–64. Published online 2022 May 12. doi: 10.1530/EJE-21-1183

PMCID:: PMC9248914

Abstract Article PDF–2.9M

Select item 84829669.

O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells

Logan J Massman, Michael Pereckas, Nathan T Zwagerman, Stephanie Olivier-Van Stichelen

Endocrinology. 2021 Dec; 162(12): bqab178. Published online 2021 Aug 21. doi: 10.1210/endocr/bqab178

PMCID:: PMC8482966

Abstract Article

Select item 837265710.

Two Distinctive POMC Promoters Modify Gene Expression in Cushing Disease

Takako Araki, Yukiko Tone, Masaaki Yamamoto, Hiraku Kameda, Anat Ben-Shlomo, Shozo Yamada, Akira Takeshita, Masato Yamamoto, Yasuhiko Kawakami, Masahide Tone, Shlomo Melmed

J Clin Endocrinol Metab. 2021 Sep; 106(9): e3346–e3363. Published online 2021 Jun 1. doi: 10.1210/clinem/dgab387

PMCID:: PMC8372657

Abstract Article

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 799361112.

Hypopigmented burn hypertrophic scar contains melanocytes that can be signaled to re-pigment by synthetic alpha-melanocyte stimulating hormone in vitro

Bonnie C. Carney, Taryn E. Travis, Lauren T. Moffatt, Laura S. Johnson, Melissa M. McLawhorn, Cynthia M. Simbulan-Rosenthal, Dean S. Rosenthal, Jeffrey W. Shupp

PLoS One. 2021; 16(3): e0248985. Published online 2021 Mar 25. doi: 10.1371/journal.pone.0248985

PMCID:: PMC7993611

Abstract Article PDF–5.3M

Select item 781408313.

Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy

Divija Deshpande, Nitin Agarwal, Thomas Fleming, Claire Gaveriaux-Ruff, Christoph S. N. Klose, Anke Tappe-Theodor, Rohini Kuner, Peter Nawroth

Nat Commun. 2021; 12: 426. Published online 2021 Jan 18. doi: 10.1038/s41467-020-20677-0

Correction in:: Nat Commun. 2021; 12: 989.

PMCID:: PMC7814083

Abstract Article PDF–6.6M

Select item 727938414.

Mitochondrial Dynamics and Microglia as New Targets in Metabolism Regulation

Martina Chiurazzi, Martina Di Maro, Mauro Cozzolino, Antonio Colantuoni

Int J Mol Sci. 2020 May; 21(10): 3450. Published online 2020 May 13. doi: 10.3390/ijms21103450

PMCID:: PMC7279384

Abstract Article PDF–1.1M

Select item 719069915.

Anti-inflammatory effects of α-MSH through p-CREB expression in sarcoidosis like granuloma model

Chongxu Zhang, Stephanie Chery, Aaron Lazerson, Norman H Altman, Robert Jackson, Greg Holt, Michael Campos, Andrew V Schally, Mehdi Mirsaeidi

Sci Rep. 2020; 10: 7277. Published online 2020 Apr 29. doi: 10.1038/s41598-020-64305-9

PMCID:: PMC7190699

Abstract Article PDF–2.8M

Select item 716998316.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 672201417.

Persistent changes in stress-regulatory genes in pregnant woman or a child with prenatal alcohol exposure

Dipak K. Sarkar, Omkaram Gangisetty, Jeffrey R. Wozniak, Judith K. Eckerle, Michael K. Georgieff, Tatiana M Foroud, Leah Wetherill, Wladimir Wertelecki, Christina D. Chambers, Edward Riley, Natalya Zymak-Zakutnya, Lyubov Yevtushok

Alcohol Clin Exp Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Alcohol Clin Exp Res. 2019 Sep; 43(9): 1887–1897. Published online 2019 Aug 6. doi: 10.1111/acer.14148

PMCID:: PMC6722014

Abstract Article PDF–1.5M

Select item 667455018.

Corticotropin-Releasing Factor within the Central Nucleus of the Amygdala Mediates Enhanced Ethanol Self-Administration in Withdrawn, Ethanol-Dependent Rats

Cindy K. Funk, Laura E. O'Dell, Elena F. Crawford, George F. Koob

J Neurosci. 2006 Nov 1; 26(44): 11324–11332. doi: 10.1523/JNEUROSCI.3096-06.2006

PMCID:: PMC6674550

Abstract Article PDF–629K

Select item 662152919.

Food Intake Adaptation to Dietary Fat Involves PSA-Dependent Rewiring of the Arcuate Melanocortin System in Mice

Alexandre Benani, Cécile Hryhorczuk, Alexandra Gouazé, Xavier Fioramonti, Xavier Brenachot, Christophe Guissard, Alice Krezymon, Thibaut Duparc, André Colom, Emmanuelle Nédélec, Caroline Rigault, Aleth Lemoine, Jean Gascuel, Rita Gerardy-Schahn, Philippe Valet, Claude Knauf, Anne Lorsignol, Luc Pénicaud

J Neurosci. 2012 Aug 29; 32(35): 11970–11979. doi: 10.1523/JNEUROSCI.0624-12.2012

PMCID:: PMC6621529

Abstract Article PDF–2.0M

Select item 661954720.

Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively

Cheng Zhan, Jingfeng Zhou, Qiru Feng, Ju-en Zhang, Shuailiang Lin, Junhong Bao, Ping Wu, Minmin Luo

J Neurosci. 2013 Feb 20; 33(8): 3624–3632. doi: 10.1523/JNEUROSCI.2742-12.2013

PMCID:: PMC6619547

Abstract Article PDF–2.3M

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