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Select item 110646591.

Cytoplasmic redox imbalance in the thioredoxin system activates Hsf1 and results in hyperaccumulation of the sequestrase Hsp42 with misfolded proteins

Davi Goncalves, Duong Long Duy, Sara Peffer, Kevin A. Morano

Mol Biol Cell. 2024 Apr 1; 35(4): ar53. Published online 2024 Mar 5. doi: 10.1091/mbc.E23-07-0296

PMCID:: PMC11064659

Abstract Article PDF–1.6M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517004.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 105516985.

Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding

Michela Ciccarelli, Anna E. Masser, Jayasankar Mohanakrishnan Kaimal, Jordi Planells, Claes Andréasson

Mol Biol Cell. 2023 Sep 1; 34(10): ar101. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-05-0153

PMCID:: PMC10551698

Abstract Article PDF–5.4M

Select item 105211376.

Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress

Andreas Hadjicharalambous, Alex J. Whale, Geylani Can, J. Mark Skehel, Jonathan M. Houseley, Philip Zegerman

Version 1. Wellcome Open Res. 2023; 8: 327. Published online 2023 Jul 26. doi: 10.12688/wellcomeopenres.19617.1

PMCID:: PMC10521137

Abstract Article PDF–4.0M

Select item 102977007.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 95085538.

Oxidation of two cysteines within yeast Hsp70 impairs proteostasis while directly triggering an Hsf1-dependent cytoprotective response

Alec Santiago, Kevin A. Morano

J Biol Chem. 2022 Oct; 298(10): 102424. Published online 2022 Aug 27. doi: 10.1016/j.jbc.2022.102424

PMCID:: PMC9508553

Abstract Article PDF–1.7M

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 868471110.

Hsf1 activation by proteotoxic stress requires concurrent protein synthesis

Blake W. Tye, L. Stirling Churchman

Mol Biol Cell. 2021 Sep 1; 32(19): 1800–1806. doi: 10.1091/mbc.E21-01-0014

PMCID:: PMC8684711

Abstract Article PDF–1.4M

Select item 835174611.

Cell adaptation to aneuploidy by the environmental stress response dampens induction of the cytosolic unfolded-protein response

Andrew J. Kane, Christopher M. Brennan, Acer E. Xu, Eric J. Solís, Allegra Terhorst, Vladimir Denic, Angelika Amon

Mol Biol Cell. 2021 Aug 15; 32(17): 1557–1564. doi: 10.1091/mbc.E21-03-0104

PMCID:: PMC8351746

Abstract Article PDF–817K

Select item 825725412.

ReporterSeq reveals genome-wide dynamic modulators of the heat shock response across diverse stressors

Brian D Alford, Eduardo Tassoni-Tsuchida, Danish Khan, Jeremy J Work, Gregory Valiant, Onn Brandman

eLife. 2021; 10: e57376. Published online 2021 Jul 5. doi: 10.7554/eLife.57376

PMCID:: PMC8257254

Abstract Article PDF–4.7M

Select item 774881613.

Subcellular localization of the J-protein Sis1 regulates the heat shock response

Zoë A. Feder, Asif Ali, Abhyudai Singh, Joanna Krakowiak, Xu Zheng, Vytas P. Bindokas, Donald Wolfgeher, Stephen J. Kron, David Pincus

J Cell Biol. 2021 Jan 4; 220(1): e202005165. Published online 2020 Dec 16. doi: 10.1083/jcb.202005165

PMCID:: PMC7748816

Abstract Article PDF–4.6M

Select item 774630814.

CAF-1 and Rtt101p function within the replication-coupled chromatin assembly network to promote H4 K16ac, preventing ectopic silencing

Tiffany J. Young, Yi Cui, Claire Pfeffer, Emilie Hobbs, Wenjie Liu, Joseph Irudayaraj, Ann L. Kirchmaier

PLoS Genet. 2020 Dec; 16(12): e1009226. Published online 2020 Dec 7. doi: 10.1371/journal.pgen.1009226

PMCID:: PMC7746308

Abstract Article PDF–3.2M

Select item 772272815.

Sis1 potentiates the stress response to protein aggregation and elevated temperature

Courtney L. Klaips, Michael H. M. Gropp, Mark S. Hipp, F. Ulrich Hartl

Nat Commun. 2020; 11: 6271. Published online 2020 Dec 8. doi: 10.1038/s41467-020-20000-x

PMCID:: PMC7722728

Abstract Article PDF–1.8M

Select item 771875916.

Chemical-Genetic Interactions with the Proline Analog L-Azetidine-2-Carboxylic Acid in Saccharomyces cerevisiae

Matthew D. Berg, Yanrui Zhu, Joshua Isaacson, Julie Genereaux, Raphaël Loll-Krippleber, Grant W. Brown, Christopher J. Brandl

G3 (Bethesda) 2020 Dec; 10(12): 4335–4345. Published online 2020 Oct 20. doi: 10.1534/g3.120.401876

PMCID:: PMC7718759

Abstract Article PDF–2.3M

Select item 771875117.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 744969618.

Transient intracellular acidification regulates the core transcriptional heat shock response

Catherine G Triandafillou, Christopher D Katanski, Aaron R Dinner, D Allan Drummond

eLife. 2020; 9: e54880. Published online 2020 Aug 7. doi: 10.7554/eLife.54880

PMCID:: PMC7449696

Abstract Article PDF–4.6M

Select item 727317719.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 703273220.

Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast

Wei-Chun Au, Tianyi Zhang, Prashant K. Mishra, Jessica R. Eisenstatt, Robert L. Walker, Josefina Ocampo, Anthony Dawson, Jack Warren, Michael Costanzo, Anastasia Baryshnikova, Karin Flick, David J. Clark, Paul S. Meltzer, Richard E. Baker, Chad Myers, Charles Boone, Peter Kaiser, Munira A. Basrai

PLoS Genet. 2020 Feb; 16(2): e1008597. Published online 2020 Feb 7. doi: 10.1371/journal.pgen.1008597