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Items: 1 to 20 of 133

1.
The Dual Role of the NFATc2/galectin‐9 Axis in Modulating Tumor‐Initiating Cell Phenotypes and Immune Suppression in Lung Adenocarcinoma
Zhi‐Jie Xiao, Si‐Qi Wang, Jun‐Jiang Chen, Yun Li, Yuchen Jiang, Vicky Pui‐Chi Tin, Jia Liu, Huiyi Hu, Maria Pik Wong, Yihang Pan, Judy Wai Ping Yam
Adv Sci (Weinh) 2024 May; 11(20): 2306059. Published online 2024 Mar 25. doi: 10.1002/advs.202306059
PMCID:
PMC11132051
AbstractArticlePDF–8.1M
2.
The RNA m6A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer
Lichen Ge, Yalan Rui, Cheng Wang, Yingmin Wu, Hongsheng Wang, Junjun Wang
Cell Death Dis. 2024 Mar; 15(3): 192. Published online 2024 Mar 6. doi: 10.1038/s41419-024-06566-0
PMCID:
PMC10917814
AbstractArticlePDF–13M
3.
Report and literature review of four cases of EWSR1::NFATC2 round cell sarcoma
Lili Liu, Lan Li, Yi Ding, Fangzhou Kong, Wenfa Mo, Hongtao Ye, Danhua Shen
Diagn Pathol. 2024; 19: 19. Published online 2024 Jan 22. doi: 10.1186/s13000-024-01443-y
PMCID:
PMC10801936
AbstractArticlePDF–2.3M
4.
Effect of NFATc2- and Sp1-mediated TNFalpha Regulation on the Proliferation and Migration Behavior of Pancreatic Cancer Cells
MANUELA MALSY, BERNHARD GRAF, ELISABETH BRUENDL, CONSTANTIN MAIER-STOCKER, ANIKA BUNDSCHERER
Cancer Genomics Proteomics. 2023 Nov-Dec; 20(6 Suppl): 706–711. Published online 2023 Nov 3. doi: 10.21873/cgp.20417
PMCID:
PMC10687727
AbstractArticlePDF–847K
5.
NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells
Ju A Shim, So Min Lee, Jin Woo Jeong, Hyori Kim, Woo Jae Son, Jun Hong Park, Parkyong Song, Sin-Hyeog Im, Sangsu Bae, Jung-Hyun Park, Yuna Jo, Changwan Hong
Cell Commun Signal. 2023; 21: 309. Published online 2023 Oct 30. doi: 10.1186/s12964-023-01326-7
PMCID:
PMC10617197
AbstractArticlePDF–5.1M
6.
Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice
Li Ni, Satadru K Lahiri, Jiali Nie, Xiaolu Pan, Issam Abu-Taha, Julia O Reynolds, Hannah M Campbell, Haihao Wang, Markus Kamler, Wilhelm Schmitz, Frank Ulrich Müller, Na Li, Xiang Wei, Dao Wen Wang, Dobromir Dobrev, Xander H T Wehrens
Cardiovasc Res. 2022 Sep; 118(13): 2805–2818. Published online 2021 Oct 14. doi: 10.1093/cvr/cvab325
PMCID:
PMC9586567
AbstractArticlePDF–1.6M
7.
Expanding the Spectrum of EWSR1-NFATC2-rearranged Benign Tumors: A Common Genomic Abnormality in Vascular Malformation/Hemangioma and Simple Bone Cyst
Sheena L.M. Ong, Suk Wai Lam, Brendy E.W.M. van den Akker, Herman M. Kroon, Inge H. Briaire-de Bruijn, Arjen H.G. Cleven, Dilara C. Savci-Heijink, Anne-Marie Cleton-Jansen, Daniel Baumhoer, Karoly Szuhai, Judith V.M.G. Bovée
Am J Surg Pathol. 2021 Dec; 45(12): 1669–1681. Published online 2021 Jun 3. doi: 10.1097/PAS.0000000000001748
PMCID:
PMC8598111
AbstractArticlePDF–1.0M
8.
Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation
Shane P. Simonett, Sunyoung Shin, Jacob A. Herring, Rhonda Bacher, Linsin A. Smith, Chenyang Dong, Mary E. Rabaglia, Donnie S. Stapleton, Kathryn L. Schueler, Jeea Choi, Matthew N. Bernstein, Daniel R. Turkewitz, Carlos Perez-Cervantes, Jason Spaeth, Roland Stein, Jeffery S. Tessem, Christina Kendziorski, Sündüz Keleş, Ivan P. Moskowitz, Mark P. Keller, Alan D. Attie
J Clin Invest. 2021 Nov 1; 131(21): e144833. Published online 2021 Nov 1. doi: 10.1172/JCI144833
PMCID:
PMC8553569
AbstractArticlePDF–2.7M
9.
Expression and clinical significance of IL7R, NFATc2, and RNF213 in familial and sporadic multiple sclerosis
Seyedeh Zahra Hosseini Imani, Zohreh Hojati, Sheyda Khalilian, Fariba Dehghanian, Majid Kheirollahi, Mehdi Khorrami, Vahid Shaygannejad, Omid Mirmosayyeb
Sci Rep. 2021; 11: 19260. Published online 2021 Sep 28. doi: 10.1038/s41598-021-98691-5
PMCID:
PMC8478940
AbstractArticlePDF–1.7M
10.
The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca2+ entry
Pulak Kar, Yu-Ping Lin, Rajesh Bhardwaj, Charles J. Tucker, Gary S. Bird, Matthias A. Hediger, Carina Monico, Nader Amin, Anant B. Parekh
Proc Natl Acad Sci U S A. 2021 May 11; 118(19): e2012908118. Published online 2021 May 3. doi: 10.1073/pnas.2012908118
PMCID:
PMC8126794
AbstractArticlePDF–2.0M
11.
EWSR1-NFATC2 gene fusion in a soft tissue tumor with epithelioid round cell morphology and abundant stroma: a case report and review of the literature
Jarish N. Cohen, Amit J. Sabnis, Gregor Krings, Soo-Jin Cho, Andrew E. Horvai, Jessica L. Davis
Hum Pathol. Author manuscript; available in PMC 2021 May 7.
Published in final edited form as: Hum Pathol. 2018 Nov; 81: 281–290. Published online 2018 Apr 4. doi: 10.1016/j.humpath.2018.03.020
PMCID:
PMC8104452
AbstractArticlePDF–1.8M
12.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
13.
FGF19/SOCE/NFATc2 signaling circuit facilitates the self-renewal of liver cancer stem cells
Jingchun Wang, Huakan Zhao, Lu Zheng, Yu Zhou, Lei Wu, Yanquan Xu, Xiao Zhang, Guifang Yan, Halei Sheng, Rong Xin, Lu Jiang, Juan Lei, Jiangang Zhang, Yu Chen, Jin Peng, Qian Chen, Shuai Yang, Kun Yu, Dingshan Li, Qichao Xie, Yongsheng Li
Theranostics. 2021; 11(10): 5045–5060. Published online 2021 Mar 5. doi: 10.7150/thno.56369
PMCID:
PMC7978301
AbstractArticlePDF–2.7M
14.
Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells
Dong Hyun Kim, Hee Young Kim, Sunjung Cho, Su-Jin Yoo, Won-Ju Kim, Hye Ran Yeon, Kyungho Choi, Je-Min Choi, Seong Wook Kang, Won-Woo Lee
eLife. 2021; 10: e61841. Published online 2021 Jan 28. doi: 10.7554/eLife.61841
PMCID:
PMC7872515
AbstractArticlePDF–4.8M
15.
Role of nuclear factor of activated T cells 2 (NFATc2) in allergic asthma
Marielena Jakobi, Alexander Kiefer, Hooman Mirzakhani, Manfred Rauh, Theodor Zimmermann, Paraskevi Xepapadaki, Barbara Stanic, Mubeccel Akdis, Nikolaos G. Papadopoulos, Benjamin A. Raby, Scott T. Weiss, Susetta Finotto
Immun Inflamm Dis. 2020 Dec; 8(4): 704–712. Published online 2020 Oct 20. doi: 10.1002/iid3.360
PMCID:
PMC7654396
AbstractArticlePDF–934K
16.
DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma
Christian Koelsche, Mark Kriegsmann, Felix K.F. Kommoss, Damian Stichel, Katharina Kriegsmann, Christian Vokuhl, Thomas G.P. Grünewald, Laura Romero-Pérez, Thomas Kirchner, Enrique de Alava, Juan Diaz-Martin, Wolfgang Hartmann, Daniel Baumhoer, Cristina R. Antonescu, Karoly Szuhai, Uta Flucke, Uta Dirksen, Stefan M. Pfister, David T.W. Jones, Gunhild Mechtersheimer, Andreas von Deimling
J Cancer Res Clin Oncol. Author manuscript; available in PMC 2020 Nov 3.
Published in final edited form as: J Cancer Res Clin Oncol. 2019 May; 145(5): 1273–1281. Published online 2019 Mar 20. doi: 10.1007/s00432-019-02895-2
PMCID:
PMC7607515
AbstractArticlePDF–1.3M
17.
NUCLEAR FACTOR OF ACTIVATED T CELLS 1 AND 2 ARE REQUIRED FOR VERTEBRAL HOMEOSTASIS
Ernesto Canalis, Lauren Schilling, Tabitha Eller, Jungeun Yu
J Cell Physiol. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: J Cell Physiol. 2020 Nov; 235(11): 8520–8532. Published online 2020 Apr 24. doi: 10.1002/jcp.29696
PMCID:
PMC7529842
AbstractArticlePDF–2.2M
18.
STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation
Ga-Yeon Son, Krishna Prasad Subedi, Hwei Ling Ong, Lucile Noyer, Hassan Saadi, Changyu Zheng, Rajesh Bhardwaj, Stefan Feske, Indu Suresh Ambudkar
Proc Natl Acad Sci U S A. 2020 Jul 14; 117(28): 16638–16648. Published online 2020 Jun 29. doi: 10.1073/pnas.1915386117
PMCID:
PMC7368200
AbstractArticlePDF–2.1M
19.
Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC
Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong
eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223
PMCID:
PMC6927754
AbstractArticlePDF–5.1M
20.
An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells
Valentina Perotti, Paola Baldassari, Alessandra Molla, Gabriella Nicolini, Ilaria Bersani, Giulia Grazia, Fabio Benigni, Andrea Maurichi, Mario Santinami, Andrea Anichini, Roberta Mortarini
Oncogene. 2019; 38(22): 4384–4396. Published online 2019 Feb 1. doi: 10.1038/s41388-019-0729-2
PMCID:
PMC6756060
AbstractArticlePDF–2.3M

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