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Items: 1 to 20 of 149

1.
Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity
Jamie Russell, Luming Chen, Aijie Liu, Jianhui Wang, Subarna Ghosh, Xue Zhong, Hexin Shi, Bruce Beutler, Evan Nair-Gill
EMBO Rep. 2024 Aug; 25(8): 3601–3626. Published online 2024 Jul 2. doi: 10.1038/s44319-024-00191-w
PMCID:
PMC11315911
AbstractArticlePDF–6.6M
2.
PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression
Yan Xu, Qian Zhou, Xiaoming Wang, Aijun Zhang, Wentao Qi, Yuan Li, Chengzu Zheng, Jianmin Guan, Tao Sun, Jingxin Li, Chunhua Lu, Yuemao Shen, Baobing Zhao1
Haematologica. 2024 Jun 1; 109(6): 1800–1814. Published online 2023 Dec 7. doi: 10.3324/haematol.2023.284041
PMCID:
PMC11141684
AbstractArticlePDF–4.1M
3.
Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC
Hila Winer, Wenqing Li, Gisele Rodrigues, Tim Gower, Thomas Joshua Meyer, Julie Hixon, Scott K. Durum
Haematologica. 2024 Jun 1; 109(6): 1726–1740. Published online 2023 Nov 30. doi: 10.3324/haematol.2023.283559
PMCID:
PMC11141644
AbstractArticlePDF–4.7M
4.
A novel 268 kb deletion combined with a splicing variant in IL7R causes of severe combined immunodeficiency in a Chinese family: a case report
Lulu Yan, Yan He, Yuxin Zhang, Yingwen Liu, Limin Xu, Chunxiao Han, Yudan Zhao, Haibo Li
BMC Med Genomics. 2023; 16: 323. Published online 2023 Dec 11. doi: 10.1186/s12920-023-01765-8
PMCID:
PMC10712040
AbstractArticlePDF–1.5M
5.
Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma
Danqi Fu, Jingrui Yan, Zhaoyu Zhang, Yang Liu, Xiaoqing Ma, Jinsheng Ding, Shengyu Yang, Ran Zhao, Antao Chang, Chuntao Gao, Jing Liu, Tiansuo Zhao, Xiuchao Wang, Chongbiao Huang, Song Gao, Ying Ma, Bo Tang, Yukuan Feng, Hongwei Wang, Jihui Hao
Cancer Biol Med. 2023 Aug 15; 20(8): 599–626. Published online 2023 Jun 27. doi: 10.20892/j.issn.2095-3941.2023.0039
PMCID:
PMC10476466
AbstractArticlePDF–4.1M
6.
In vivo availability of the cytokine IL-7 constrains the survival and homeostasis of peripheral iNKT cells
Joo-Young Park, Hee Yeun Won, Devon T. DiPalma, Hye Kyung Kim, Tae-Hyoun Kim, Can Li, Noriko Sato, Changwan Hong, Ninan Abraham, Ronald E. Gress, Jung-Hyun Park
Cell Rep. Author manuscript; available in PMC 2023 Jun 26.
Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110219. doi: 10.1016/j.celrep.2021.110219
PMCID:
PMC10292121
AbstractArticlePDF–2.8M
7.
In patients with primary Sjögren’s syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells
Anneline C. Hinrichs, Aike A. Kruize, Helen L. Leavis, Joel A. G. van Roon
Front Immunol. 2022; 13: 1017157. Published online 2022 Nov 24. doi: 10.3389/fimmu.2022.1017157
PMCID:
PMC9729251
AbstractArticlePDF–8.1M
8.
IL7RA single nucleotide polymorphisms are associated with the size and function of the MAIT cell population in treated HIV-1 infection
Fei Han, Muhammad Yaaseen Gulam, Yichao Zheng, Nurul Syuhada Zulhaimi, Wan Rong Sia, Dan He, Amanda Ho, Leila Hadadi, Zhenyu Liu, Peiwu Qin, Peter E. Lobie, Adeeba Kamarulzaman, Lin-Fa Wang, Johan K. Sandberg, Sharon R. Lewin, Reena Rajasuriar, Edwin Leeansyah
Front Immunol. 2022; 13: 985385. Published online 2022 Oct 20. doi: 10.3389/fimmu.2022.985385
PMCID:
PMC9632172
AbstractArticlePDF–4.9M
9.
IL‐7 is expressed in malignant mesothelioma and has a prognostic value
Hoa‐Le Mai, Sophie Deshayes, Thi‐Van‐Ha Nguyen, Virginie Dehame, Anne‐Laure Chéné, Sophie Brouard, Christophe Blanquart
Mol Oncol. 2022 Oct; 16(20): 3606–3619. Published online 2022 Sep 10. doi: 10.1002/1878-0261.13310
PMCID:
PMC9580880
AbstractArticlePDF–1.4M
10.
The Role of IL-7 and IL-7R in Cancer Pathophysiology and Immunotherapy
Chunli Wang, Lingzu Kong, Seokmin Kim, Sunyoung Lee, Sechan Oh, Seona Jo, Inhwan Jang, Tae-Don Kim
Int J Mol Sci. 2022 Sep; 23(18): 10412. Published online 2022 Sep 8. doi: 10.3390/ijms231810412
PMCID:
PMC9499417
AbstractArticlePDF–1.6M
11.
IL-7/IL7R axis dysfunction in adults with severe community-acquired pneumonia (CAP): a cross-sectional study
Sandra Ampuero, Guillermo Bahamonde, Fabián Tempio, María Luisa Garmendia, Mauricio Ruiz, Rolando Pizarro, Patricio Rossi, Lucía Huenchur, Luis Lizama, Mercedes López, Luis F. Avendaño, Vivian Luchsinger
Sci Rep. 2022; 12: 13145. Published online 2022 Jul 30. doi: 10.1038/s41598-022-13063-x
PMCID:
PMC9339003
AbstractArticlePDF–1.1M
12.
Low IL7R Expression at Diagnosis Predicted Relapse in Adult Acute Myeloid Leukemia Patients With t(8;21)
Nan Xu, Kai Sun, Ya-Zhe Wang, Wen-Min Chen, Jun Wang, Ling-Di Li, Xu Wang, Yue Hao, Yan Chang, Yan-Rong Liu, Xiao-Jun Huang, Ya-Zhen Qin
Front Immunol. 2022; 13: 909104. Published online 2022 Jul 7. doi: 10.3389/fimmu.2022.909104
PMCID:
PMC9302488
AbstractArticlePDF–1.0M
13.
Antisense modulation of IL7R splicing to control sIL7R expression in human CD4+ T cells
Gaddiel Galarza-Muñoz, Debbie Kennedy-Boone, Geraldine Schott, Shelton S. Bradrick, Mariano A. Garcia-Blanco
RNA. 2022 Aug; 28(8): 1058–1073. doi: 10.1261/rna.079137.122
PMCID:
PMC9297843
AbstractArticlePDF–3.9M
14.
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia
Ifat Geron, Angela Maria Savino, Hila Fishman, Noa Tal, John Brown, Virginia A. Turati, Chela James, Jolanda Sarno, Michal Hameiri-Grossman, Yu Nee Lee, Avigail Rein, Hillary Maniriho, Yehudit Birger, Anna Zemlyansky, Inna Muler, Kara L. Davis, Victoria Marcu-Malina, Nicole Mattson, Oren Parnas, Rabea Wagener, Ute Fischer, João T. Barata, Catriona H. M. Jamieson, Markus Müschen, Chun-Wei Chen, Arndt Borkhardt, Ilan Richard Kirsch, Arnon Nagler, Tariq Enver, Shai Izraeli
Nat Commun. 2022; 13: 659. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28218-7
PMCID:
PMC8814001
AbstractArticlePDF–4.2M
15.
CD127 imprints functional heterogeneity to diversify monocyte responses in inflammatory diseases
Bin Zhang, Yuan Zhang, Lei Xiong, Yuzhe Li, Yunliang Zhang, Jiuliang Zhao, Hui Jiang, Can Li, Yunqi Liu, Xindong Liu, Haofei Liu, Yi-Fang Ping, Qiangfeng Cliff Zhang, Zheng Zhang, Xiu-Wu Bian, Yan Zhao, Xiaoyu Hu
J Exp Med. 2022 Feb 7; 219(2): e20211191. Published online 2022 Jan 11. doi: 10.1084/jem.20211191
PMCID:
PMC8757045
AbstractArticlePDF–5.8M
16.
Interleukin-7 receptor α mutational activation can initiate precursor B-cell acute lymphoblastic leukemia
Afonso R. M. Almeida, João L. Neto, Ana Cachucho, Mayara Euzébio, Xiangyu Meng, Rathana Kim, Marta B. Fernandes, Beatriz Raposo, Mariana L. Oliveira, Daniel Ribeiro, Rita Fragoso, Priscila P. Zenatti, Tiago Soares, Mafalda R. de Matos, Juliana Ronchi Corrêa, Mafalda Duque, Kathryn G. Roberts, Zhaohui Gu, Chunxu Qu, Clara Pereira, Susan Pyne, Nigel J. Pyne, Vasco M. Barreto, Isabelle Bernard-Pierrot, Emannuelle Clappier, Charles G. Mullighan, Ana R. Grosso, J. Andrés Yunes, João T. Barata
Nat Commun. 2021; 12: 7268. Published online 2021 Dec 14. doi: 10.1038/s41467-021-27197-5
PMCID:
PMC8671594
AbstractArticlePDF–5.1M
17.
Expression and clinical significance of IL7R, NFATc2, and RNF213 in familial and sporadic multiple sclerosis
Seyedeh Zahra Hosseini Imani, Zohreh Hojati, Sheyda Khalilian, Fariba Dehghanian, Majid Kheirollahi, Mehdi Khorrami, Vahid Shaygannejad, Omid Mirmosayyeb
Sci Rep. 2021; 11: 19260. Published online 2021 Sep 28. doi: 10.1038/s41598-021-98691-5
PMCID:
PMC8478940
AbstractArticlePDF–1.7M
18.
Expression and Polymorphism of TSLP/TSLP Receptors as Potential Diagnostic Markers of Colorectal Cancer Progression
Abdelhabib Semlali, Mikhlid H. Almutairi, Abdullah Alamri, Narasimha Reddy Parine, Maha Arafah, Majid A. Almadi, Abdulrahman M. Aljebreen, Othman Alharbi, Nahla Ali Azzam, Riyadh Almutairi, Mohammad Alanazi, Mahmoud Rouabhia
Genes (Basel) 2021 Sep; 12(9): 1386. Published online 2021 Sep 6. doi: 10.3390/genes12091386
PMCID:
PMC8469613
AbstractArticlePDF–1.9M
19.
Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma
Ana Silva, Afonso R. M. Almeida, Ana Cachucho, João L. Neto, Sofie Demeyer, Mafalda de Matos, Thea Hogan, Yunlei Li, Jules Meijerink, Jan Cools, Ana Rita Grosso, Benedict Seddon, João T. Barata
Blood. 2021 Sep 23; 138(12): 1040–1052. Prepublished online 2021 May 10. doi: 10.1182/blood.2019000553
Correction in:
Blood. 2024 May 16; 143(20): 2108–2110.
PMCID:
PMC8462360
AbstractArticle
20.
Expression of KLRG1 and CD127 defines distinct CD8+ subsets that differentially impact patient outcome in follicular lymphoma
Hongyan Wu, Xinyi Tang, Hyo Jin Kim, Shahrzad Jalali, Joshua C Pritchett, Jose C Villasboas, Anne J Novak, Zhi-Zhang Yang, Stephen M Ansell
J Immunother Cancer. 2021; 9(7): e002662. Published online 2021 Jul 5. doi: 10.1136/jitc-2021-002662
PMCID:
PMC8258669
AbstractArticlePDF–12M

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