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Items: 1 to 20 of 115

1.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
2.
HIV-1 Nef Promotes Survival of Myeloid Cells by a Stat3-dependent Pathway
Scott D. Briggs, Beata Scholtz, Jean-Marc Jacque, Simon Swingler, Mario Stevenson, Thomas E. Smithgall
J Biol Chem. Author manuscript; available in PMC 2022 Sep 20.
Published in final edited form as: J Biol Chem. 2001 Jul 6; 276(27): 25605–25611. Published online 2001 Apr 27. doi: 10.1074/jbc.M103244200
PMCID:
PMC9486509
AbstractArticlePDF–1.1M
3.
A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas
Manit Munshi, Xia Liu, Amanda Kofides, Nickolas Tsakmaklis, Maria Luisa Guerrera, Zachary R. Hunter, M. Lia Palomba, Kimon V. Argyropoulos, Christopher J. Patterson, Alexa G. Canning, Kirsten Meid, Joshua Gustine, Andrew R. Branagan, Catherine A. Flynn, Shayna Sarosiek, Jorge J. Castillo, Jinhua Wang, Sara J. Buhrlage, Nathanael S. Gray, Nikhil C. Munshi, Kenneth C. Anderson, Steven P. Treon, Guang Yang
Blood Adv. 2022 Jun 14; 6(11): 3332–3338. Published online 2022 Jun 3. doi: 10.1182/bloodadvances.2021006147
PMCID:
PMC9198919
AbstractArticlePDF–1.4M
4.
HCK is a Potential Prognostic Biomarker that Correlates with Immune Cell Infiltration in Acute Myeloid Leukemia
Fang Cheng, Qiang Li, Jinglin Wang, Liu Wang, Weiming Li, Fang Zeng
Dis Markers. 2022; 2022: 3199589. Published online 2022 Mar 4. doi: 10.1155/2022/3199589
PMCID:
PMC8916870
AbstractArticlePDF–4.4M
5.
HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML
Zheng Li, Fangce Wang, Xiaoxue Tian, Jun Long, Bin Ling, Wenjun Zhang, Jun Xu, Aibin Liang
J Exp Clin Cancer Res. 2021; 40: 210. Published online 2021 Jun 24. doi: 10.1186/s13046-021-02007-4
PMCID:
PMC8223385
AbstractArticlePDF–7.8M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Selective targeting of the inactive state of hematopoietic cell kinase (Hck) with a stable curcumin derivative
Manas Pratim Chakraborty, Sudipta Bhattacharyya, Souryadip Roy, Indira Bhattacharya, Rahul Das, Arindam Mukherjee
J Biol Chem. 2021 Jan-Jun; 296: 100449. Published online 2021 Feb 20. doi: 10.1016/j.jbc.2021.100449
PMCID:
PMC7946438
AbstractArticlePDF–2.7M
8.
Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma
Hildo C. Lantermans, Marthe Minderman, Annemieke Kuil, Marie-José Kersten, Steven T. Pals, Marcel Spaargaren
Leukemia. 2021; 35(3): 881–886. Published online 2020 Jun 26. doi: 10.1038/s41375-020-0934-6
PMCID:
PMC7932922
AbstractArticlePDF–870K
9.
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients
Xudong Zhu, Yixiao Zhang, Yang Bai, Xi Gu, Guanglei Chen, Lisha Sun, Yulun Wang, Xinbo Qiao, Qingtian Ma, Tong Zhu, Jiawen Bu, Jinqi Xue, Caigang Liu
Int J Med Sci. 2020; 17(17): 2773–2789. Published online 2020 Sep 30. doi: 10.7150/ijms.43161
PMCID:
PMC7645343
AbstractArticlePDF–3.9M
10.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
11.
Membrane anchoring of Hck kinase via the intrinsically disordered SH4-U and lengthscale associated with subcellular localization
Matthew P. Pond, Rebecca Eells, Bradley W. Treece, Frank Heinrich, Mathias Lösche, Benoît Roux
J Mol Biol. Author manuscript; available in PMC 2021 Apr 17.
Published in final edited form as: J Mol Biol. 2020 Apr 17; 432(9): 2985–2997. Published online 2019 Dec 23. doi: 10.1016/j.jmb.2019.11.024
PMCID:
PMC7301414
AbstractArticlePDF–1.9M
12.
HCK promotes glioblastoma progression by TGFβ signaling
Zhenlin Wang, Chenting Ying, Anke Zhang, Houshi Xu, Yang Jiang, Meiqing Lou
Biosci Rep. 2020 Jun 26; 40(6): BSR20200975. Published online 2020 Jun 17. doi: 10.1042/BSR20200975
PMCID:
PMC7300285
AbstractArticlePDF–1.2M
13.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
14.
Nucleotide binding domain and leucine-rich repeat pyrin domain-containing protein 12: characterization of its binding to hematopoietic cell kinase
Yue Zhang, Curtis T. Okamoto
Int J Biol Sci. 2020; 16(9): 1507–1525. Published online 2020 Mar 5. doi: 10.7150/ijbs.41798
PMCID:
PMC7097926
AbstractArticlePDF–2.5M
15.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
16.
Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance
Ravi K. Patel, Mark C. Weir, Kexin Shen, Daniel Snyder, Vaughn S. Cooper, Thomas E. Smithgall
PLoS One. 2019; 14(12): e0225887. Published online 2019 Dec 2. doi: 10.1371/journal.pone.0225887
PMCID:
PMC6886798
AbstractArticlePDF–3.8M
17.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
18.
Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN
Bin Liu, Shangwen Jiang, Min Li, Xuelian Xiong, Mingrui Zhu, Duanzhuo Li, Lei Zhao, Lili Qian, Linhui Zhai, Jing Li, Han Lu, Shengnan Sun, Jiandie Lin, Yan Lu, Xiaoying Li, Minjia Tan
Nat Commun. 2018; 9: 4770. Published online 2018 Nov 13. doi: 10.1038/s41467-018-07185-y
PMCID:
PMC6233205
AbstractArticlePDF–1.6M
19.
Suppression of autophagy and HCK signaling promotes PTGS2high FCGR3− NK cell differentiation triggered by ectopic endometrial stromal cells
Jie Mei, Wen-Jie Zhou, Xiao-Yong Zhu, Han Lu, Ke Wu, Hui-Li Yang, Qiang Fu, Chun-Yan Wei, Kai-Kai Chang, Li-Ping Jin, Jian Wang, Yong-Ming Wang, Da-Jin Li, Ming-Qing Li
Autophagy. 2018; 14(8): 1376–1397. Published online 2018 Jul 20. doi: 10.1080/15548627.2018.1476809
PMCID:
PMC6103661
AbstractArticlePDF–5.2M
20.
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel
eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879
PMCID:
PMC5999396
AbstractArticlePDF–3.6M

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