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Items: 1 to 20 of 292

1.
KCNK1 promotes proliferation and metastasis of breast cancer cells by activating lactate dehydrogenase A (LDHA) and up-regulating H3K18 lactylation
Xiangchan Hou, Jiawei Ouyang, Le Tang, Pan Wu, Xiangying Deng, Qijia Yan, Lei Shi, Songqing Fan, Chunmei Fan, Can Guo, Qianjin Liao, Yong Li, Wei Xiong, Guiyuan Li, Zhaoyang Zeng, Fuyan Wang
PLoS Biol. 2024 Jun; 22(6): e3002666. Published online 2024 Jun 21. doi: 10.1371/journal.pbio.3002666
PMCID:
PMC11192366
AbstractArticlePDF–7.6M
2.
Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression
Fatima Khan, Yiyun Lin, Heba Ali, Lizhi Pang, Madeline Dunterman, Wen-Hao Hsu, Katie Frenis, R. Grant Rowe, Derek A. Wainwright, Kathleen McCortney, Leah K. Billingham, Jason Miska, Craig Horbinski, Maciej S. Lesniak, Peiwen Chen
Nat Commun. 2024; 15: 1987. Published online 2024 Mar 5. doi: 10.1038/s41467-024-46193-z
PMCID:
PMC10914854
AbstractArticlePDF–10M
3.
Cytoplasmic localization of SETDB1-induced Warburg effect via c-MYC-LDHA axis enhances migration and invasion in breast carcinoma
Wenlin Yang, Yingze Wei, Ting Wang, Ying Xu, Xiaoxia Jin, Hongyan Qian, Shuyun Yang, Song He
Int J Mol Med. 2024 Apr; 53(4): 40. Published online 2024 Feb 28. doi: 10.3892/ijmm.2024.5364
PMCID:
PMC10914311
AbstractArticlePDF–9.6M
4.
LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m6A modification in triple‐negative breast cancer
Yuanhang Yu, Huifang Deng, Wenwen Wang, Shihan Xiao, Renjing Zheng, Lianqiu Lv, Han Wang, Jianying Chen, Bo Zhang
Clin Transl Med. 2024 Feb; 14(2): e1583. Published online 2024 Feb 19. doi: 10.1002/ctm2.1583
PMCID:
PMC10875709
AbstractArticlePDF–15M
5.
Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional complex
Feixia Wang, Li Chen, Desong Kong, Xiaojin Zhang, Siwei Xia, Baoyu Liang, Yang Li, Ya Zhou, Zili Zhang, Jiangjuan Shao, Shizhong Zheng, Feng Zhang
Hepatology. 2024 Mar; 79(3): 606–623. Published online 2023 Sep 21. doi: 10.1097/HEP.0000000000000569
PMCID:
PMC10871634
AbstractArticlePDF–2.0M
6.
Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma
Kunyuan Wang, Qianting Lu, Yufeng Luo, Ganxiang Yu, Zhilei Wang, Jiaen Lin, Zhenlin Tan, Yueqiong Lao, Shiming Liu, Hui Yang
Biol Direct. 2024; 19: 4. Published online 2024 Jan 2. doi: 10.1186/s13062-023-00442-1
PMCID:
PMC10759731
AbstractArticlePDF–7.6M
7.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
8.
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté
J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123
PMCID:
PMC10480535
AbstractArticlePDF–2.4M
9.
The mRNA and protein levels of the glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase platelet (PFKP) are good predictors of survival time, recurrence, and risk of death in cervical cancer patients
Verónica Bolaños‐Suárez, Ana Alfaro, Ana María Espinosa, Ingrid Medina‐Martínez, Eligia Juárez, Nicolás Villegas‐Sepúlveda, Marco Gudiño‐Zayas, América Gutiérrez‐Castro, Edgar Román‐Bassaure, María Eugenia Salinas‐Nieves, Sergio Bruno‐Muñoz, Carlos Aranda, Oscar Flores‐Herrera, Jaime Berumen
Cancer Med. 2023 Jul; 12(14): 15632–15649. Published online 2023 Jun 16. doi: 10.1002/cam4.6123
PMCID:
PMC10417302
AbstractArticlePDF–12M
10.
The novel role of LDHA/LDHB in the prognostic value and tumor-immune infiltration in clear cell renal cell carcinoma
Jie Chen, Fei Wu, Yehua Cao, Yuanxin Xing, Qingyong Liu, Zuohui Zhao
PeerJ. 2023; 11: e15749. Published online 2023 Aug 1. doi: 10.7717/peerj.15749
PMCID:
PMC10402698
AbstractArticlePDF–4.0M
11.
LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer
Oh Kwang Kwon, In Hyuk Bang, So Young Choi, Ju Mi Jeon, Ann-Yae Na, Yan Gao, Sam Seok Cho, Sung Hwan Ki, Youngshik Choe, Jun Nyung Lee, Yun-Sok Ha, Eun Ju Bae, Tae Gyun Kwon, Byung-Hyun Park, Sangkyu Lee
Genomics Proteomics Bioinformatics. 2023 Feb; 21(1): 177–189. Published online 2022 Mar 9. doi: 10.1016/j.gpb.2022.02.004
PMCID:
PMC10372916
AbstractArticlePDF–2.4M
12.
USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis
Shuguang Liu, Yuening Xiang, Boshi Wang, Chao Gao, Zhenping Chen, Shao Xie, Jing Wu, Yi Liu, Xiaoxi Zhao, Chao Yang, Zhixia Yue, Linya Wang, Xiaojia Wen, Ruidong Zhang, Feng Zhang, Heng Xu, Xiaowen Zhai, Huyong Zheng, Hui Zhang, Maoxiang Qian
Blood Adv. 2023 Jul 11; 7(13): 3099–3112. Published online 2023 Mar 15. doi: 10.1182/bloodadvances.2022008284
PMCID:
PMC10362547
AbstractArticlePDF–2.8M
13.
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell
J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468
PMCID:
PMC10323252
AbstractArticle
14.
Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry
Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang
Anal Chem. Author manuscript; available in PMC 2023 Jun 21.
Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986
PMCID:
PMC10284117
AbstractArticlePDF–2.5M
15.
Nuclear Translocation of LDHA Promotes the Catabolism of BCAAs to Sustain GBM Cell Proliferation through the TxN Antioxidant Pathway
Zhujun Li, Zhiyan Gu, Lan Wang, Yun Guan, Yingying Lyu, Jialong Zhang, Yin Wang, Xin Wang, Ji Xiong, Ying Liu
Int J Mol Sci. 2023 Jun; 24(11): 9365. Published online 2023 May 27. doi: 10.3390/ijms24119365
PMCID:
PMC10253380
AbstractArticlePDF–29M
16.
The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes
Haixia Ma, Valentina Sukonina, Wei Zhang, Fang Meng, Santhilal Subhash, Henrik Palmgren, Ida Alexandersson, Huiming Han, Shuping Zhou, Stefano Bartesaghi, Chandrasekhar Kanduri, Sven Enerbäck
J Biol Chem. 2023 Jun; 299(6): 104795. Published online 2023 May 5. doi: 10.1016/j.jbc.2023.104795
PMCID:
PMC10244703
AbstractArticlePDF–3.8M
17.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
18.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
19.
mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin
Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun
Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y
PMCID:
PMC10148843
AbstractArticlePDF–11M
20.
Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage
Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter
Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041
PMCID:
PMC10138931
AbstractArticlePDF–4.0M

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