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Items: 1 to 20 of 99

1.
Serum sEPCR Levels Are Elevated in Patients With Alzheimer’s Disease
Yongjian Zhu, Zhilong Chen, Xugang Chen, Sheng Hu
Am J Alzheimers Dis Other Demen. 2015 Aug; 30(5): 517–521. Published online 2015 Jan 14. doi: 10.1177/1533317514567124
PMCID:
PMC10852812
AbstractArticlePDF–184K
2.
EPCR deficiency ameliorates inflammatory arthritis in mice by suppressing the activation and migration of T cells and dendritic cells
Meilang Xue, Haiyan Lin, Hai Po Helena Liang, Lara Bereza-Malcolm, Tom Lynch, Premarani Sinnathurai, Hartmut Weiler, Christopher Jackson, Lyn March
Rheumatology (Oxford) 2024 Feb; 63(2): 571–580. Published online 2023 May 25. doi: 10.1093/rheumatology/kead230
PMCID:
PMC10834933
AbstractArticlePDF–1.4M
3.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
AbstractArticlePDF–3.6M
4.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
5.
Microvascular Environment Influences Brain Microvascular Heterogeneity: Relative Roles of Astrocytes and Oligodendrocytes for the EPCR Expression in the Brain Endothelium
Manjusha Thakar, Midrelle E. Noumbissi, Monique F. Stins
Int J Mol Sci. 2023 Apr; 24(8): 6908. Published online 2023 Apr 7. doi: 10.3390/ijms24086908
PMCID:
PMC10138692
AbstractArticlePDF–2.2M
6.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
7.
LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression
Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma
BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4
PMCID:
PMC9175482
AbstractArticlePDF–15M
8.
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus
David Stacey, Lingyan Chen, Paulina J. Stanczyk, Joanna M. M. Howson, Amy M. Mason, Stephen Burgess, Stephen MacDonald, Jonathan Langdown, Harriett McKinney, Kate Downes, Neda Farahi, James E. Peters, Saonli Basu, James S. Pankow, Weihong Tang, Nathan Pankratz, Maria Sabater-Lleal, Paul S. de Vries, Nicholas L. Smith, CHARGE Hemostasis Working Group, Amy D. Gelinas, Daniel J. Schneider, Nebojsa Janjic, Nilesh J. Samani, Shu Ye, Charlotte Summers, Edwin R. Chilvers, John Danesh, Dirk S. Paul
Nat Commun. 2022; 13: 1222. Published online 2022 Mar 9. doi: 10.1038/s41467-022-28729-3
Correction in:
Nat Commun. 2022; 13: 1962.
PMCID:
PMC8907312
AbstractArticlePDF–1.9M
9.
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma
Panpan Zhang, Qiuping He, Yaqin Wang, Guanqun Zhou, Yupei Chen, Linglong Tang, Yuan Zhang, Xiaohong Hong, Yanping Mao, Qingmei He, Xiaojing Yang, Na Liu, Jun Ma
Signal Transduct Target Ther. 2022; 7: 46. Published online 2022 Feb 16. doi: 10.1038/s41392-021-00866-z
PMCID:
PMC8847456
AbstractArticlePDF–4.6M
10.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
11.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M
12.
Lentiviral CRISPR-guided RNA library screening identified Adam17 as an upstream negative regulator of Procr in mammary epithelium
Ting Wu, Yinghua Wang, Tianxiong Xiao, Yirui Ai, Jinsong Li, Yi Arial Zeng, Qing Cissy Yu
BMC Biotechnol. 2021; 21: 42. Published online 2021 Jul 19. doi: 10.1186/s12896-021-00703-9
PMCID:
PMC8290623
AbstractArticlePDF–1.4M
13.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
14.
Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells
Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull
PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606
PMCID:
PMC7392334
AbstractArticlePDF–2.7M
15.
Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis
Jingjiao Li, Mingquan Guo, Xiaoxu Tian, Xin Wang, Xing Yang, Ping Wu, Chengrong Liu, Zixuan Xiao, Yafei Qu, Yue Yin, Chunxia Wang, Yucai Zhang, Zhaoqin Zhu, Zhenshan Liu, Chao Peng, Tongyu Zhu, Qiming Liang
Med (N Y) 2021 Jan 15; 2(1): 99–112.e7. Published online 2020 Jul 21. doi: 10.1016/j.medj.2020.07.002
PMCID:
PMC7373048
AbstractArticlePDF–3.8M
16.
Down‐regulation of endothelial protein C receptor promotes preeclampsia by affecting actin polymerization
Hao Wang, Pan Wang, Xiaoling Liang, Wenjing Li, Mo Yang, Jihong Ma, Wei Yue, Shangrong Fan
J Cell Mol Med. 2020 Mar; 24(6): 3370–3383. Published online 2020 Jan 30. doi: 10.1111/jcmm.15011
PMCID:
PMC7131931
AbstractArticlePDF–2.1M
17.
Endothelial protein C receptor polymorphisms and risk of severe sepsis in critically ill patients
Alice G. Vassiliou, Nikolaos A. Maniatis, Anastasia Kotanidou, Marina Kallergi, Foteini S. Karystinaki, Eleftheria Letsiou, Constantinos Glynos, Petros Kopterides, Dimitra Vassiliadi, Nikitas Nikitas, Ioanna Dimopoulou, Apostolos Armaganidis, Stylianos E. Orfanos
Intensive Care Med. 2013; 39(10): 1752–1759. Published online 2013 Jul 24. doi: 10.1007/s00134-013-3018-5
PMCID:
PMC7095157
AbstractArticlePDF–210K
18.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
19.
Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis
Weicheng Zang, Chuanzhen Yang, Tingting Li, Liming Liao, Xiaofeng Zheng
Proc Natl Acad Sci U S A. 2019 Dec 17; 116(51): 25624–25633. Published online 2019 Dec 3. doi: 10.1073/pnas.1910250116
PMCID:
PMC6926050
AbstractArticlePDF–1.4M
20.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M

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