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Items: 1 to 20 of 22

1.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
2.
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα
Evelyn Ramberger, Valeria Sapozhnikova, Elisabeth Kowenz-Leutz, Karin Zimmermann, Nathalie Nicot, Petr V. Nazarov, Daniel Perez-Hernandez, Ulf Reimer, Philipp Mertins, Gunnar Dittmar, Achim Leutz
iScience. 2021 Jun 25; 24(6): 102686. Published online 2021 Jun 4. doi: 10.1016/j.isci.2021.102686
PMCID:
PMC8220391
AbstractArticlePDF–4.4M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination
Li Xing, Xiaolong Tang, Kaikai Wu, Xiong Huang, Yi Yi, Jinliang Huan
Mol Ther Nucleic Acids. 2020 Dec 4; 22: 910–923. Published online 2020 Oct 15. doi: 10.1016/j.omtn.2020.10.012
PMCID:
PMC7666371
AbstractArticlePDF–4.6M
5.
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens
Michael S. Haney, Christopher J. Bohlen, David W Morgens, James A. Ousey, Amira A. Barkal, C. Kimberly Tsui, Braeden Ego, Roni Levin, Roarke Kamber, Hannah Collins, Andrew Tucker, Amy Li, Daan Vorselen, Lorenzo Labitigan, Emily Crane, Evan Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, William J. Greenleaf, Billy Li, Michael P. Snyder, Irving L. Weissman, Julie A. Theriot, Sean R. Collins, Ben A. Barres, Michael C. Bassik
Nat Genet. Author manuscript; available in PMC 2019 Sep 3.
Published in final edited form as: Nat Genet. 2018 Dec; 50(12): 1716–1727. Published online 2018 Nov 5. doi: 10.1038/s41588-018-0254-1
PMCID:
PMC6719718
AbstractArticlePDF–1.3M
6.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
7.
Decreased expression of ARHGAP15 promotes the development of colorectal cancer through PTEN/AKT/FOXO1 axis
Shengli Pan, Yingying Deng, Jun Fu, Yuhao Zhang, Zhijin Zhang, Xiaokun Ru, Xianju Qin
Cell Death Dis. 2018 Jun; 9(6): 673. Published online 2018 Jun 4. doi: 10.1038/s41419-018-0707-6
PMCID:
PMC5986807
AbstractArticlePDF–5.2M
8.
ARHGAP15 in Human Breast Carcinoma: A Potent Tumor Suppressor Regulated by Androgens
Kiyoshi Takagi, Yasuhiro Miki, Yoshiaki Onodera, Takanori Ishida, Mika Watanabe, Hironobu Sasano, Takashi Suzuki
Int J Mol Sci. 2018 Mar; 19(3): 804. Published online 2018 Mar 10. doi: 10.3390/ijms19030804
PMCID:
PMC5877665
AbstractArticlePDF–3.0M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis
Snaevar Sigurdsson, Kristjan F. Alexandersson, Patrick Sulem, Bjarke Feenstra, Steinunn Gudmundsdottir, Gisli H. Halldorsson, Sigurgeir Olafsson, Asgeir Sigurdsson, Thorunn Rafnar, Thorgeir Thorgeirsson, Erik Sørensen, Andreas Nordholm-Carstensen, Jakob Burcharth, Jens Andersen, Henrik Stig Jørgensen, Emma Possfelt-Møller, Henrik Ullum, Gudmar Thorleifsson, Gisli Masson, Unnur Thorsteinsdottir, Mads Melbye, Daniel F. Gudbjartsson, Tryggvi Stefansson, Ingileif Jonsdottir, Kari Stefansson
Nat Commun. 2017; 8: 15789. Published online 2017 Jun 6. doi: 10.1038/ncomms15789
PMCID:
PMC5467205
AbstractArticlePDF–822K
11.
Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway
Zhen Sun, Biao Zhang, Chen Wang, Tao Fu, Lianling Li, Qiaoli Wu, Ying Cai, Jinhuan Wang
Cancer Sci. 2017 Jan; 108(1): 61–72. Published online 2017 Jan 23. doi: 10.1111/cas.13118
PMCID:
PMC5276829
AbstractArticlePDF–3.7M
12.
Genome-wide association study of selenium concentrations
Marilyn C. Cornelis, Myriam Fornage, Millennia Foy, Pengcheng Xun, Vadim N. Gladyshev, Steve Morris, Daniel I. Chasman, Frank B. Hu, Eric B. Rimm, Peter Kraft, Joanne M. Jordan, Dariush Mozaffarian, Ka He
Hum Mol Genet. 2015 Mar 1; 24(5): 1469–1477. Published online 2014 Oct 24. doi: 10.1093/hmg/ddu546
PMCID:
PMC4321444
AbstractArticlePDF–252K
13.
Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries
Zhen Zeng, Eleanor Feingold, Xiaojing Wang, Daniel E. Weeks, Myoungkeun Lee, Karen T. Cuenco, Barbara Broffitt, Robert J. Weyant, Richard Crout, Daniel W. McNeil, Steven M. Levy, Mary L. Marazita, John. R. Shaffer
Caries Res. Author manuscript; available in PMC 2015 Jan 1.
Published in final edited form as: Caries Res. 2014; 48(4): 330–338. doi: 10.1159/000356299
PMCID:
PMC4043868
AbstractArticlePDF–225K
14.
ArhGAP15, a Rac-specific GTPase-activating Protein, Plays a Dual Role in Inhibiting Small GTPase Signaling
Maria Radu, Sonali J. Rawat, Alexander Beeser, Anton Iliuk, Weiguo Andy Tao, Jonathan Chernoff
J Biol Chem. 2013 Jul 19; 288(29): 21117–21125. Published online 2013 Jun 11. doi: 10.1074/jbc.M113.459719
PMCID:
PMC3774378
AbstractArticlePDF–1.9M
15.
Evidence for Genes on Chromosome 2 Contributing to Alcohol Dependence With Conduct Disorder and Suicide Attempts
Danielle M. Dick, Jacquelyn Meyers, Fazil Aliev, John Nurnberger, Jr., John Kramer, Sam Kuperman, Bernice Porjesz, Jay Tischfield, Howard J. Edenberg, Tatiana Foroud, Marc Schuckit, Alison Goate, Victor Hesselbrock, Laura Bierut
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2013 Mar 14.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Sep; 153B(6): 1179–1188. doi: 10.1002/ajmg.b.31089
PMCID:
PMC3597340
AbstractArticlePDF–256K
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Haplotype Association Mapping of Acute Lung Injury in Mice Implicates Activin A Receptor, Type 1
George D. Leikauf, Vincent J. Concel, Pengyuan Liu, Kiflai Bein, Annerose Berndt, Koustav Ganguly, An Soo Jang, Kelly A. Brant, Maggie Dietsch, Hannah Pope-Varsalona, Richard A. Dopico, Jr., Y. P. Peter Di, Qian Li, Louis J. Vuga, Mario Medvedovic, Naftali Kaminski, Ming You, Daniel R. Prows
Am J Respir Crit Care Med. 2011 Jun 1; 183(11): 1499–1509. Published online 2011 Feb 4. doi: 10.1164/rccm.201006-0912OC
PMCID:
PMC3137140
AbstractArticlePDF–1.8M
18.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
19.
Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae
Jennifer K. Lowe, Julian B. Maller, Itsik Pe'er, Benjamin M. Neale, Jacqueline Salit, Eimear E. Kenny, Jessica L. Shea, Ralph Burkhardt, J. Gustav Smith, Weizhen Ji, Martha Noel, Jia Nee Foo, Maude L. Blundell, Vita Skilling, Laura Garcia, Marcia L. Sullivan, Heather E. Lee, Anna Labek, Hope Ferdowsian, Steven B. Auerbach, Richard P. Lifton, Christopher Newton-Cheh, Jan L. Breslow, Markus Stoffel, Mark J. Daly, David M. Altshuler, Jeffrey M. Friedman
PLoS Genet. 2009 Feb; 5(2): e1000365. Published online 2009 Feb 6. doi: 10.1371/journal.pgen.1000365
PMCID:
PMC2628735
AbstractArticlePDF–377K
20.
Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions
Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano
Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604
PMCID:
PMC515316
AbstractArticlePDF–181K

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