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Select item 117212941.

Myeloid DRP1 deficiency limits revascularization in ischemic muscles via inflammatory macrophage polarization and metabolic reprogramming

Shikha Yadav, Vijay C. Ganta, Sudhahar Varadarajan, Vy Ong, Yang Shi, Archita Das, Dipankar Ash, Sheela Nagarkoti, Malgorzata McMenamin, Stephanie Kelley, Tohru Fukai, Masuko Ushio-Fukai

JCI Insight. 2025 Jan 9; 10(1): e177334. Published online 2025 Jan 9. doi: 10.1172/jci.insight.177334

PMCID:: PMC11721294

Abstract Article PDF–3.8M

Select item 116704542.

Mechanotransduction via Endothelial Adhesion Molecule CD31 Initiates Transmigration and Reveals a Role for Vascular Endothelial Growth Factor Receptor 2 in Diapedesis

Tao Fu, David P. Sullivan, Annette M. Gonzalez, Maureen E. Haynes, Prarthana J. Dalal, Nakisha S. Rutledge, Abigail L. Tierney, Julia A. Yescas, Evan W. Weber, William A. Muller

Immunity. Author manuscript; available in PMC 2024 Dec 26.

Published in final edited form as: Immunity. 2023 Oct 10; 56(10): 2311–2324.e6. Published online 2023 Aug 28. doi: 10.1016/j.immuni.2023.08.001

PMCID:: PMC11670454

Abstract Article PDF–2.3M

Select item 116690683.

Time‐of‐day control of mitochondria regulates NLRP3 inflammasome activation in macrophages

James R. O'Siorain, Shannon L. Cox, Cloé Payet, Frances K. Nally, Yan He, Tabea T. Drewinksi, Oran D. Kennedy, Jennifer K. Dowling, Mark Mellett, James O. Early, Annie M. Curtis

FASEB J. 2024 Dec 31; 38(24): e70235. Published online 2024 Dec 17. doi: 10.1096/fj.202400508RR

PMCID:: PMC11669068

Abstract Article PDF–3.3M

Select item 116499014.

Pathobiont-induced suppressive immune imprints thwart T cell vaccine responses

Irshad Ahmed Hajam, Chih-Ming Tsai, Cesia Gonzalez, Juan Raphael Caldera, María Lázaro Díez, Xin Du, April Aralar, Brian Lin, William Duong, George Y. Liu

Nat Commun. 2024; 15: 10335. Published online 2024 Dec 16. doi: 10.1038/s41467-024-54644-w

PMCID:: PMC11649901

Abstract Article PDF–2.0M

Select item 116472415.

Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice

WonMo Ahn, Faith N. Burnett, Kamila Wojnar-Lason, Jaser Doja, Amritha Sreekumar, Pushpankur Ghoshal, Bhupesh Singla, Graydon Gonsalvez, Ryan A. Harris, Xiaoling Wang, Joseph M. Miano, Gábor Csányi

Redox Biol. 2024 Dec; 78: 103423. Published online 2024 Nov 6. doi: 10.1016/j.redox.2024.103423

PMCID:: PMC11647241

Abstract Article PDF–13M

Select item 116451256.

A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma

Sarang Tartey, Geoffrey Neale, Peter Vogel, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti

Cancer Res. Author manuscript; available in PMC 2024 Dec 13.

Published in final edited form as: Cancer Res. 2021 May 1; 81(9): 2358–2372. Published online 2021 Feb 22. doi: 10.1158/0008-5472.CAN-20-3510

PMCID:: PMC11645125

Abstract Article PDF–3.4M

Select item 116328267.

Lysine specific demethylase 1 conditional myeloid cell knockout mice have decreased osteoclast differentiation due to increased IFN-β gene expression

Kristina Astleford-Hopper, Juan E Abrahante Llorens, Elizabeth W Bradley, Kim C Mansky

JBMR Plus. 2025 Jan; 9(1): ziae142. Published online 2024 Nov 9. doi: 10.1093/jbmrpl/ziae142

PMCID:: PMC11632826

Abstract Article PDF–1.6M

Select item 116318848.

The circadian clock gene BMAL1 modulates autoimmunity features in lupus

Shuichiro Nakabo, Donavon Sandoval-Heglund, Norio Hanata, Stephen Brooks, Victoria Hoffmann, Mingzeng Zhang, William Ambler, Zerai Manna, Elaine Poncio, Sarfaraz Hasni, Shamima Islam, Stefania Dell’Orso, Mariana J. Kaplan

Front Immunol. 2024; 15: 1465185. Published online 2024 Nov 27. doi: 10.3389/fimmu.2024.1465185

PMCID:: PMC11631884

Abstract Article PDF–4.9M

Select item 116058849.

IRF4 regulates myeloid-derived suppressor cells expansion and function in Schistosoma japonicum-infected mice

Lu Zhou, Peibin Lin, Guorong Deng, Lengshan Mo, Cansheng Hong, Zhihan Jiang, Yiqiang Zhu, Yi Zhao, Yanwei Qi, Tengfei Hu, Qianlian Wu, Jian Zhang, Qingqing Li, Quan Yang

Parasit Vectors. 2024; 17: 492. Published online 2024 Nov 28. doi: 10.1186/s13071-024-06543-8

PMCID:: PMC11605884

Abstract Article PDF–8.0M

Select item 1160221910.

Reciprocal suppression between TGFβ signaling and TNF stimulation finetunes the macrophage inflammatory response

Yuhan Xia, Kazuki Inoue, Ting Zheng, Yongli Qin, Baohong Zhao

FASEB J. Author manuscript; available in PMC 2024 Nov 27.

Published in final edited form as: FASEB J. 2024 Jul 15; 38(13): e23704. doi: 10.1096/fj.202302230R

PMCID:: PMC11602219

Abstract Article PDF–2.0M

Select item 1158806511.

Monocytes give rise to Langerhans cells that preferentially migrate to lymph nodes at steady state

Hayley M. Raquer-McKay, Raul A. Maqueda-Alfaro, Sanjana Saravanan, Rebeca Arroyo Hornero, Björn E. Clausen, Andres Gottfried-Blackmore, Juliana Idoyaga

Proc Natl Acad Sci U S A. 2024 Nov 19; 121(47): e2404927121. Published online 2024 Nov 14. doi: 10.1073/pnas.2404927121

PMCID:: PMC11588065

Abstract Article PDF–9.2M

Select item 1158487612.

PDCD6 regulates lactate metabolism to modulate LC3-associated phagocytosis and antibacterial defense

Lulu Sun, Sijin Wu, Hui Wang, Tianyu Zhang, Mengyu Zhang, Xuepeng Bai, Xiumei Zhang, Bingqing Li, Cai Zhang, Yan Li, Jun Zhou, Tianliang Li

Nat Commun. 2024; 15: 10157. Published online 2024 Nov 23. doi: 10.1038/s41467-024-54377-w

PMCID:: PMC11584876

Abstract Article PDF–4.5M

Select item 1157478313.

PD-L1 restrains PD-1⁺Nrp1^lo Treg cells to suppress inflammation-driven colorectal tumorigenesis

Dakota B. Poschel, John D. Klement, Alyssa D. Merting, Chunwan Lu, Yang Zhao, Dafeng Yang, Wei Xiao, Huabin Zhu, Ponnala Rajeshwari, Michael Toscano, Kimya Jones, Amanda Barrett, Roni J. Bollag, Padraic G. Fallon, Huidong Shi, Kebin Liu

Cell Rep. Author manuscript; available in PMC 2024 Nov 19.

Published in final edited form as: Cell Rep. 2024 Oct 22; 43(10): 114819. Published online 2024 Oct 3. doi: 10.1016/j.celrep.2024.114819

PMCID:: PMC11574783

Abstract Article PDF–3.5M

Select item 1155565014.

CDS2 expression regulates de novo phosphatidic acid synthesis

Daniel M. Collins, Vishnu Janardan, David Barneda, Karen E. Anderson, Izabella Niewczas, Diane Taylor, Danye Qiu, Henning J. Jessen, Andrea F. Lopez-Clavijo, Simon Walker, Padinjat Raghu, Jonathan Clark, Len R. Stephens, Phillip T. Hawkins

Biochem J. 2024 Oct 16; 481(20): 1449–1473. Published online 2024 Oct 11. doi: 10.1042/BCJ20240456

PMCID:: PMC11555650

Abstract Article PDF–8.4M

Select item 1154940715.

Circadian rhythms of macrophages are altered by the acidic tumor microenvironment

Amelia M Knudsen-Clark, Daniel Mwangi, Juliana Cazarin, Kristina Morris, Cameron Baker, Lauren M Hablitz, Matthew N McCall, Minsoo Kim, Brian J Altman

EMBO Rep. 2024 Nov; 25(11): 5080–5112. Published online 2024 Oct 16. doi: 10.1038/s44319-024-00288-2

PMCID:: PMC11549407

Abstract Article PDF–5.9M

Select item 1154874816.

The protein segregase VCP/p97 promotes host antifungal defense via regulation of SYK activation

Zhugui Shao, Li Wang, Limin Cao, Tian Chen, Xin-Ming Jia, Wanwei Sun, Chengjiang Gao, Hui Xiao

PLoS Pathog. 2024 Oct; 20(10): e1012674. Published online 2024 Oct 29. doi: 10.1371/journal.ppat.1012674

PMCID:: PMC11548748

Abstract Article PDF–2.2M

Select item 1154439017.

Reprogramming tumor-associated macrophages and inhibiting tumor neovascularization by targeting MANF–HSF1–HSP70-1 pathway: An effective treatment for hepatocellular carcinoma

Dan Han, Qiannan Ma, Petek Ballar, Chunyang Zhang, Min Dai, Xiaoyuan Luo, Jiong Gu, Chuansheng Wei, Panhui Guo, Lulu Zeng, Min Hu, Can Jiang, Yanyan Liang, Yanyan Wang, Chao Hou, Xian Wang, Lijie Feng, Yujun Shen, Yuxian Shen, Xiangpeng Hu, Jun Liu

Acta Pharm Sin B. 2024 Oct; 14(10): 4396–4412. Published online 2024 May 10. doi: 10.1016/j.apsb.2024.05.001

PMCID:: PMC11544390

Abstract Article PDF–6.7M

Select item 1154073218.

Stored RBC Transfusions Leads to the Systemic Inflammatory Response Syndrome in Anemic Murine Neonates

Balamurugan Ramatchandirin, Marie Amalie Balamurugan, Suneetha Desiraju, Yerin Chung, Boguslaw S. Wojczyk, Krishnan MohanKumar

Inflamm Res. Author manuscript; available in PMC 2024 Nov 7.

Published in final edited form as: Inflamm Res. 2024 Nov; 73(11): 1859–1873. Published online 2024 Sep 5. doi: 10.1007/s00011-024-01936-y

PMCID:: PMC11540732

Abstract Article PDF–1.8M

Select item 1153448219.

Neutrophil pyroptosis regulates corneal wound healing and post‐injury neovascularisation

Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Shanzhi Wang, Kyung Eun Lee, Bingchuan Geng, Jongsoo Kim, Bao Zhao, Qiang Wang, Haitao Wen, Heather L. Chandler, Hua Zhu

Clin Transl Med. 2024 Nov; 14(11): e1762. Published online 2024 Nov 4. doi: 10.1002/ctm2.1762

PMCID:: PMC11534482

Abstract Article PDF–15M

Select item 1153012820.

The STAT3/SETDB2 axis dictates NF-κB–mediated inflammation in macrophages during wound repair

Kevin D. Mangum, Aaron denDekker, Qinmengge Li, Lam C. Tsoi, Amrita D. Joshi, William J. Melvin, Sonya J. Wolf, Jadie Y. Moon, Christopher O. Audu, James Shadiow, Andrea T. Obi, Rachael Wasikowski, Emily C. Barrett, Tyler M. Bauer, Kylie Boyer, Zara Ahmed, Frank M. Davis, Johann Gudjonsson, Katherine A. Gallagher

JCI Insight. 2024 Oct 22; 9(20): e179017. Published online 2024 Oct 22. doi: 10.1172/jci.insight.179017