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Items: 1 to 20 of 247

1.
Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity
Haojie Dong, Xin He, Lei Zhang, Wei Chen, Yi-Chun Lin, Song-Bai Liu, Huafeng Wang, Le Xuan Truong Nguyen, Min Li, Yinghui Zhu, Dandan Zhao, Lucy Ghoda, Jonathan Serody, Benjamin Vincent, Leo Luznik, Ivana Gojo, Joshua Zeidner, Rui Su, Jianjun Chen, Ritin Sharma, Patrick Pirrotte, Xiwei Wu, Weidong Hu, Weidong Han, Binghui Shen, Ya-Huei Kuo, Jie Jin, Amandeep Salhotra, Jeffrey Wang, Guido Marcucci, Yun Lyna Luo, Ling Li
Nat Cancer. 2024; 5(4): 601–624. Published online 2024 Feb 27. doi: 10.1038/s43018-024-00736-x
PMCID:
PMC11056319
AbstractArticlePDF–33M
2.
HLA-DQ8 Supports Development of Insulitis Mediated By Insulin-Reactive Human TCR-Transgenic T-cells In NOD Mice
Jeremy J. Racine, Adel Misherghi, Jennifer R. Dwyer, Richard Maser, Elvira Forte, Olivia Bedard, Susanne Sattler, Alberto Pugliese, Laurie Landry, Colleen Elso, Maki Nakayama, Stuart Mannering, Nadia Rosenthal, David V. Serreze
J Immunol. Author manuscript; available in PMC 2024 Dec 15.
Published in final edited form as: J Immunol. 2023 Dec 15; 211(12): 1792–1805. doi: 10.4049/jimmunol.2300303
PMCID:
PMC10939972
AbstractArticlePDF–1.6M
3.
NLGN4X TCR transgenic T cells to treat gliomas
Christoper Krämer, Michael Kilian, Yu-Chan Chih, Alexandros Kourtesakis, Dirk C Hoffmann, Tamara Boschert, Philipp Koopmann, Khwab Sanghvi, Alice De Roia, Stefanie Jung, Kristine Jähne, Bryan Day, Lenny D Shultz, Miriam Ratliff, Richard Harbottle, Edward W Green, Rainer Will, Wolfgang Wick, Michael Platten, Lukas Bunse
Neuro Oncol. 2024 Feb; 26(2): 266–278. Published online 2023 Sep 16. doi: 10.1093/neuonc/noad172
PMCID:
PMC10836769
AbstractArticlePDF–3.4M
4.
A narrow T cell receptor repertoire instructs thymic differentiation of MHC class Ib–restricted CD8+ regulatory T cells
Hye-Jung Kim, Hidetoshi Nakagawa, John Y. Choi, Xuchun Che, Andrew Divris, Qingshi Liu, Andrew E. Wight, Hengcheng Zhang, Anis Saad, Zhabiz Solhjou, Christa Deban, Jamil R. Azzi, Harvey Cantor
J Clin Invest. 2024 Jan 2; 134(1): e170512. Published online 2024 Jan 2. doi: 10.1172/JCI170512
PMCID:
PMC10760956
AbstractArticlePDF–2.1M
5.
Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer
Peter Zanvit, Dewald van Dyk, Christine Fazenbaker, Kelly McGlinchey, Weichuan Luo, Jessica M. Pezold, John Meekin, Chien-ying Chang, Rosa A. Carrasco, Shannon Breen, Crystal Sao-Fong Cheung, Ariel Endlich-Frazier, Benjamin Clark, Nina J. Chu, Alessio Vantellini, Philip L. Martin, Clare E. Hoover, Kenesha Riley, Steve M. Sweet, David Chain, Yeoun Jin Kim, Eric Tu, Nathalie Harder, Sandrina Phipps, Melissa Damschroder, Ryan N. Gilbreth, Mark Cobbold, Gordon Moody, Emily E. Bosco
J Clin Invest. 2023 Nov 15; 133(22): e169655. Published online 2023 Nov 15. doi: 10.1172/JCI169655
PMCID:
PMC10645390
AbstractArticlePDF–2.6M
6.
The promiscuous development of an unconventional Qa1b-restricted T cell population
Michael Manoharan Valerio, Kathya Arana, Jian Guan, Shiao Wei Chan, Xiaokun Yang, Nadia Kurd, Angus Lee, Nilabh Shastri, Laurent Coscoy, Ellen A. Robey
Front Immunol. 2023; 14: 1250316. Published online 2023 Oct 31. doi: 10.3389/fimmu.2023.1250316
PMCID:
PMC10644506
AbstractArticlePDF–2.8M
7.
Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model
Jiwon Yang, Jing Jiao, Kyle M. Draheim, Guoxiang Yang, Hongyuan Yang, Li-Chin Yao, Leonard D. Shultz, Dale L. Greiner, Deepa Rajagopal, Sandrine Vessillier, Curtis C. Maier, Sunish Mohanan, Danying Cai, Mingshan Cheng, Michael A. Brehm, James G. Keck
FASEB J. Author manuscript; available in PMC 2024 Jun 1.
Published in final edited form as: FASEB J. 2023 Jun; 37(6): e22995. doi: 10.1096/fj.202300040R
PMCID:
PMC10242584
AbstractArticlePDF–1.6M
8.
Class Ib MHC–Mediated Immune Interactions Play a Critical Role in Maintaining Mucosal Homeostasis in the Mammalian Large Intestine
Suryasarathi Dasgupta, Igor Maricic, Jay Tang, Stephen Wandro, Kelly Weldon, Carolina S. Carpenter, Lars Eckmann, Jesus Rivera-Nieves, William Sandborn, Rob Knight, Peter Dorrestein, Austin D. Swafford, Vipin Kumar
Immunohorizons. Author manuscript; available in PMC 2023 Mar 20.
Published in final edited form as: Immunohorizons. 2021 Dec 15; 5(12): 953–971. Published online 2021 Dec 15. doi: 10.4049/immunohorizons.2100090
PMCID:
PMC10026853
AbstractArticlePDF–2.5M
9.
Targeting the recurrent Rac1P29S neoepitope in melanoma with heterologous high-affinity T cell receptors
Lena Immisch, George Papafotiou, Nerea Gallarín Delgado, Vivian Scheuplein, Annette Paschen, Thomas Blankenstein, Gerald Willimsky
Front Immunol. 2023; 14: 1119498. Published online 2023 Feb 16. doi: 10.3389/fimmu.2023.1119498
PMCID:
PMC9978334
AbstractArticlePDF–2.2M
10.
Deciphering the immunopeptidome in vivo reveals novel tumor antigens
Alex M. Jaeger, Lauren E. Stopfer, Ryuhjin Ahn, Emma A. Sanders, Demi A. Sandel, William A. Freed-Pastor, William M. Rideout, III, Santiago Naranjo, Tim Fessenden, Kim B. Nguyen, Peter S. Winter, Ryan E. Kohn, Peter M. K. Westcott, Jason Schenkel, Sean-Luc Shanahan, Alex K. Shalek, Stefani Spranger, Forest M. White, Tyler Jacks
Nature. Author manuscript; available in PMC 2023 Feb 22.
Published in final edited form as: Nature. 2022 Jul; 607(7917): 149–155. Published online 2022 Jun 15. doi: 10.1038/s41586-022-04839-2
PMCID:
PMC9945857
AbstractArticlePDF–2.7M
11.
Mechanisms of CD40-dependent cDC1 licensing beyond costimulation
Renee Wu, Ray A. Ohara, Suin Jo, Tian-Tian Liu, Stephen T. Ferris, Feiya Ou, Sunkyung Kim, Derek J. Theisen, David A. Anderson, III, Brian W. Wong, Timothy Gershon, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Nat Immunol. Author manuscript; available in PMC 2023 Feb 3.
Published in final edited form as: Nat Immunol. 2022 Nov; 23(11): 1536–1550. Published online 2022 Oct 21. doi: 10.1038/s41590-022-01324-w
PMCID:
PMC9896965
AbstractArticlePDF–2.6M
12.
Dendritic cells can prime anti-tumor CD8+ T cell responses through major histocompatibility complex cross-dressing
Brendan W. MacNabb, Sravya Tumuluru, Xiufen Chen, James Godfrey, Darshan N. Kasal, Jovian Yu, Marlieke L. M. Jongsma, Robbert M. Spaapen, Douglas E. Kline, Justin Kline
Immunity. Author manuscript; available in PMC 2023 Jun 14.
Published in final edited form as: Immunity. 2022 Jun 14; 55(6): 982–997.e8. Published online 2022 May 25. doi: 10.1016/j.immuni.2022.04.016
Correction in:
Immunity. 2022 Nov 8; 55(11): 2206–2208.
PMCID:
PMC9883788
AbstractArticlePDF–3.2M
13.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
14.
Programme of Self-Reactive Innate-Like T Cell-Mediated Cancer Immunity
Chun Chou, Xian Zhang, Chirag Krishna, Briana G. Nixon, Saida Dadi, Kristelle J. Capistrano, Emily R. Kansler, Miranda Steele, Jian Han, Amy Shyu, Jing Zhang, Efstathios G. Stamatiades, Ming Liu, Shun Li, Mytrang H. Do, Davina S. Kang, Chin-Tung Chen, Iris H. Wei, Emmanouil P Pappou, Martin R. Weiser, J. Garcia-Aguilar, J. Joshua Smith, Christina S. Leslie, Ming O. Li
Nature. Author manuscript; available in PMC 2022 Jul 2.
Published in final edited form as: Nature. 2022 May; 605(7908): 139–145. Published online 2022 Apr 20. doi: 10.1038/s41586-022-04632-1
PMCID:
PMC9250102
AbstractArticlePDF–7.2M
15.
The nonclassical MHC class I Qa-1 expressed in layer 6 neurons regulates activity-dependent plasticity via microglial CD94/NKG2 in the cortex
Ioana A. Marin, Alan Y. Gutman-Wei, Kylie S. Chew, Aram J. Raissi, Maja Djurisic, Carla J. Shatz
Proc Natl Acad Sci U S A. 2022 Jun 7; 119(23): e2203965119. Published online 2022 Jun 1. doi: 10.1073/pnas.2203965119
PMCID:
PMC9191652
AbstractArticlePDF–4.6M
16.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
17.
Robust control of a brain-persisting parasite through MHC I presentation by infected neurons
Anna Salvioni, Marcy Belloy, Aurore Lebourg, Emilie Bassot, Vincent Cantaloube-Ferrieu, Virginie Vasseur, Sophie Blanié, Roland S. Liblau, Elsa Suberbielle, Ellen A. Robey, Nicolas Blanchard
Cell Rep. Author manuscript; available in PMC 2022 Mar 10.
Published in final edited form as: Cell Rep. 2019 Jun 11; 27(11): 3254–3268.e8. doi: 10.1016/j.celrep.2019.05.051
PMCID:
PMC8908772
AbstractArticlePDF–2.0M
18.
Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice
Jamilah Abusarah, Fatemeh Khodayarian, Nehme El-Hachem, Natasha Salame, Martin Olivier, Mohammad Balood, Katiane Roversi, Sebastien Talbot, Jean-Pierre Bikorimana, Jingkui Chen, Mario Jolicoeur, Louis-Eric Trudeau, Samaneh Kamyabiazar, Borhane Annabi, Francis Robert, Jerry Pelletier, Abed-El-Hakim El-Kadiry, Riam Shammaa, Moutih Rafei
Cell Rep Med. 2021 Dec 21; 2(12): 100455. Published online 2021 Dec 21. doi: 10.1016/j.xcrm.2021.100455
PMCID:
PMC8714858
AbstractArticlePDF–5.8M
19.
CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection
Yu-Jung Lu, Palmira Barreira-Silva, Shayla Boyce, Jennifer Powers, Kelly Cavallo, Samuel M. Behar
Cell Rep. Author manuscript; available in PMC 2021 Sep 26.
Published in final edited form as: Cell Rep. 2021 Sep 14; 36(11): 109696. doi: 10.1016/j.celrep.2021.109696
PMCID:
PMC8466141
AbstractArticlePDF–2.3M
20.
Alloantibodies Prevent the Induction of Transplantation Tolerance by Enhancing Alloreactive T cell Priming
Audrea M. Burns, Anita S. Chong
J Immunol. Author manuscript; available in PMC 2021 Aug 9.
Published in final edited form as: J Immunol. 2011 Jan 1; 186(1): 214–221. Published online 2010 Dec 6. doi: 10.4049/jimmunol.1001172
PMCID:
PMC8351406
AbstractArticlePDF–484K

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