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Items: 1 to 20 of 287

1.
Proximity labeling reveals dynamic changes in the SQSTM1 protein network
Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin
J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621
PMCID:
PMC11401034
AbstractArticlePDF–5.4M
2.
The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE)
Jengmin Kang, Kwang Chul Chung
Cell Mol Life Sci. 2015 Jan; 72(1): 181–195. Published online 2014 Jun 20. doi: 10.1007/s00018-014-1665-5
PMCID:
PMC11113242
AbstractArticlePDF–1.4M
3.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740
PMCID:
PMC11109483
AbstractArticlePDF–2.9M
4.
Understanding the molecular mechanism of pathogenic variants of BIR2 domain in XIAP-deficient inflammatory bowel disease
Juhwan Lee, Kyoung Mi Sim, Mooseok Kang, Hyun Ju Oh, Ho Jung Choi, Yeong Eun Kim, Chan-Gi Pack, Kyunggon Kim, Kyung Mo Kim, Seak Hee Oh, Inki Kim, Iksoo Chang
Sci Rep. 2024; 14: 853. Published online 2024 Jan 9. doi: 10.1038/s41598-023-50932-5
PMCID:
PMC10774423
AbstractArticlePDF–2.2M
5.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
6.
Ehrlichia Notch signaling induction promotes XIAP stability and inhibits apoptosis
LaNisha L. Patterson, Caitlan D. Byerly, Regina Solomon, Nicholas Pittner, Duc Cuong Bui, Jignesh Patel, Jere W. McBride
Infect Immun. 2023 Sep; 91(9): e00002-23. Published online 2023 Aug 18. doi: 10.1128/iai.00002-23
PMCID:
PMC10501217
AbstractArticlePDF–2.3M
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
USP47 deubiquitylates Groucho/TLE to Promote Wnt-β-catenin Signaling
Sara Kassel, Alison J. Hanson, Hassina Benchabane, Kenyi Saito-Diaz, Carly R. Cabel, Lily Goldsmith, Muhammad Taha, Aksheta Kanuganti, Victoria H. Ng, George Xu, Fei Ye, Julia Picker, Fillip Port, Michael Boutros, Vivian L. Weiss, David J. Robbins, Curtis A. Thorne, Yashi Ahmed, Ethan Lee
Sci Signal. Author manuscript; available in PMC 2023 Aug 7.
Published in final edited form as: Sci Signal. 2023 Feb 7; 16(771): eabn8372. Published online 2023 Feb 7. doi: 10.1126/scisignal.abn8372
PMCID:
PMC10038201
AbstractArticlePDF–1.6M
9.
Caspase‐8‐driven apoptotic and pyroptotic crosstalk causes cell death and IL‐1β release in X‐linked inhibitor of apoptosis (XIAP) deficiency
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien‐Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James M Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lanlan Geng, James E Vince
EMBO J. 2023 Mar; 42(5): e110468. Published online 2023 Jan 17. doi: 10.15252/embj.2021110468
PMCID:
PMC9975961
AbstractArticlePDF–4.4M
10.
Caspase-3, Caspase-8 and XIAP Gene Expression in the Placenta: Exploring the Causes of Spontaneous Preterm Labour
Vera Belousova, Oxana Svitich, Elena Timokhina, Irina Ignatko, Irina Bogomazova, Svetlana Pesegova, Tatiana Silaeva, Tatiana Kuzmina, Oxana Skorobogatova
Int J Mol Sci. 2023 Jan; 24(2): 1692. Published online 2023 Jan 15. doi: 10.3390/ijms24021692
PMCID:
PMC9867413
AbstractArticlePDF–523K
11.
XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7
Bao‐qin Liu, Rong‐bei Liu, Wen‐ping Li, Xin‐tao Mao, Yi‐ning Li, Tao Huang, Hao‐li Wang, Hao‐tian Chen, Jiang‐yan Zhong, Bing Yang, Ren‐jie Chai, Qian Cao, Jin Jin, Yi‐yuan Li
EMBO Rep. 2023 Jan; 24(1): e55387. Published online 2022 Nov 17. doi: 10.15252/embr.202255387
PMCID:
PMC9827551
AbstractArticlePDF–3.3M
12.
X-linked inhibitor of apoptosis protein (XIAP) predicts disease-free survival in BRAFV600E mutant papillary thyroid carcinoma in middle eastern patients
Sandeep Kumar Parvathareddy, Abdul K. Siraj, Rong Bu, Kaleem Iqbal, Maha Al-Rasheed, Wael Al-Haqawi, Padmanaban Annaiyappanaidu, Nabil Siraj, Saeeda O. Ahmed, Saif S. Al-Sobhi, Fouad Al-Dayel, Khawla S. Al-Kuraya
Front Endocrinol (Lausanne) 2022; 13: 1054882. Published online 2022 Dec 12. doi: 10.3389/fendo.2022.1054882
PMCID:
PMC9790986
AbstractArticlePDF–568K
13.
A new intracellular targeting motif in the cytoplasmic tail of the spike protein may act as a target to inhibit SARS-CoV-2 assembly
Longbo Hu, Yongjie Tang, Lingling Mei, Mengdi Liang, Jinxian Huang, Xufei Wang, Liping Wu, Jiajing Jiang, Leyi Li, Fei Long, Jing Xiao, Long Tan, Shaohua Lu, Tao Peng
Antiviral Res. 2023 Jan; 209: 105509. Published online 2022 Dec 24. doi: 10.1016/j.antiviral.2022.105509
PMCID:
PMC9788845
AbstractArticlePDF–6.6M
14.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
15.
Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1
Christine Engelmann, Patrick Schuhmachers, Hana Zdimerova, Sanamjeet Virdi, Mathias Hauri-Hohl, Jana Pachlopnik Schmid, Adam Grundhoff, Rebecca A. Marsh, Wendy Wei-Lynn Wong, Christian Münz
Cell Death Dis. 2022 Oct; 13(10): 892. Published online 2022 Oct 22. doi: 10.1038/s41419-022-05337-z
PMCID:
PMC9587222
AbstractArticlePDF–3.6M
16.
Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner
Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas
Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3
PMCID:
PMC9360443
AbstractArticlePDF–5.8M
17.
BRCA mutations lead to XIAP overexpression and sensitise ovarian cancer to inhibitor of apoptosis (IAP) family inhibitors
Mattia Cremona, Cassandra J. Vandenberg, Angela M. Farrelly, Stephen F. Madden, Clare Morgan, Roshni Kalachand, Jessica N. McAlpine, Sinead Toomey, David G. Huntsman, Liam Grogan, Oscar Breathnach, Patrick Morris, Mark S. Carey, Clare L. Scott, Bryan T. Hennessy
Br J Cancer. 2022 Aug 1; 127(3): 488–499. Published online 2022 Apr 30. doi: 10.1038/s41416-022-01823-5
PMCID:
PMC9345958
AbstractArticlePDF–1.2M
18.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
19.
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration
Mila Daoud, Pia Nora Broxtermann, Fabian Schorn, J Paul Werthenbach, Jens Michael Seeger, Lars M Schiffmann, Kerstin Brinkmann, Domagoj Vucic, Thomas Tüting, Cornelia Mauch, Dagmar Kulms, Paola Zigrino, Hamid Kashkar
EMBO Rep. 2022 Jun; 23(6): e53608. Published online 2022 Apr 19. doi: 10.15252/embr.202153608
PMCID:
PMC9171690
AbstractArticlePDF–2.1M
20.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M

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