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Items: 1 to 20 of 1594

1.
Somatostatin interneuron fate-mapping and structure in a Pten knockout model of epilepsy
Austin W. Drake, Lilian G. Jerow, Justin V. Ruksenas, Carlie McCoy, Steve C. Danzer
Front Cell Neurosci. 2024; 18: 1474613. Published online 2024 Oct 21. doi: 10.3389/fncel.2024.1474613
PMCID:
PMC11532043
AbstractArticlePDF–12M
2.
Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
Anne Huber, Amr H. Allam, Christine Dijkstra, Stefan Thiem, Jennifer Huynh, Ashleigh R. Poh, Joshua Konecnik, Saumya P. Jacob, Rita Busuttil, Yang Liao, David Chisanga, Wei Shi, Mariah G. Alorro, Stephen Forrow, Daniele V.F. Tauriello, Eduard Batlle, Alex Boussioutas, David S. Williams, Michael Buchert, Matthias Ernst, Moritz F. Eissmann
Cell Rep. 2024 Aug 27; 43(8): 114616. Published online 2024 Aug 9. doi: 10.1016/j.celrep.2024.114616
PMCID:
PMC11372443
AbstractArticle
3.
Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer
Sheng-Yu Ku, Yanqing Wang, Maria Mica Garcia, Yasutaka Yamada, Kei Mizuno, Mark D. Long, Spencer Rosario, Meenalakshmi Chinnam, Majd Al Assaad, Loredana Puca, Min Jin Kim, Martin K. Bakht, Varadha Balaji Venkadakrishnan, Brian D. Robinson, Andrés M. Acosta, Kristine M. Wadosky, Juan Miguel Mosquera, David W. Goodrich, Himisha Beltran
J Clin Invest. 2024 Sep 3; 134(17): e175217. Published online 2024 Jul 18. doi: 10.1172/JCI175217
PMCID:
PMC11364388
AbstractArticlePDF–21M
4.
PTEN acts as a crucial inflammatory checkpoint controlling TLR9/IL-6 axis in B cells
Pei-Ju Tsai, Ming-Yu Chen, Wei-Chan Hsu, Su-Fang Lin, Po-Chiang Chan, Hsin-Hsin Chen, Cheng-Yuan Kao, Wen-Jye Lin, Tsung-Hsien Chuang, Guann-Yi Yu, Yu-Wen Su
iScience. 2024 Jul 19; 27(7): 110388. Published online 2024 Jun 26. doi: 10.1016/j.isci.2024.110388
PMCID:
PMC11292540
AbstractArticlePDF–5.3M
5.
Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina
Yacine Touahri, Joseph Hanna, Nobuhiko Tachibana, Satoshi Okawa, Hedy Liu, Luke Ajay David, Thomas Olender, Lakshmy Vasan, Alissa Pak, Dhruv Nimesh Mehta, Vorapin Chinchalongporn, Anjali Balakrishnan, Robert Cantrup, Rajiv Dixit, Pierre Mattar, Fermisk Saleh, Yaroslav Ilnytskyy, Monzur Murshed, Paul E. Mains, Igor Kovalchuk, Julie L. Lefebvre, Hon S. Leong, Michel Cayouette, Chao Wang, Antonio del Sol, Marjorie Brand, Benjamin E. Reese, Carol Schuurmans
Cell Rep. Author manuscript; available in PMC 2024 Jul 31.
Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114005. Published online 2024 Mar 27. doi: 10.1016/j.celrep.2024.114005
PMCID:
PMC11290456
AbstractArticlePDF–2.2M
6.
A Transcriptomics Analysis of the Regulation of Lens Fiber Cell Differentiation in the Absence of FGFRs and PTEN
Anil Upreti, Stephanie L. Padula, Jacob M. Weaver, Brad D. Wagner, Allison M. Kneller, Anthony L. Petulla, Salil A. Lachke, Michael L. Robinson
Cells. 2024 Jul; 13(14): 1222. Published online 2024 Jul 19. doi: 10.3390/cells13141222
PMCID:
PMC11274593
AbstractArticlePDF–4.1M
7.
Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblasts
Baotong Zhang, Mingcheng Liu, Fengyi Mai, Xiawei Li, Wenzhou Wang, Qingqing Huang, Xiancai Du, Weijian Ding, Yixiang Li, Benjamin G. Barwick, Jianping Jenny Ni, Adeboye O. Osunkoya, Yuanli Chen, Wei Zhou, Siyuan Xia, Jin-Tang Dong
J Clin Invest. 2024 Jul 15; 134(14): e175949. Published online 2024 May 23. doi: 10.1172/JCI175949
PMCID:
PMC11245161
AbstractArticlePDF–22M
8.
Identification of genes that promote PI3K pathway activation and prostate tumour formation
Jeffrey C. Francis, Amy Capper, Alistair G. Rust, Klea Ferro, Jian Ning, Wei Yuan, Johann de Bono, Stephen J. Pettitt, Amanda Swain
Oncogene. 2024; 43(24): 1824–1835. Published online 2024 Apr 23. doi: 10.1038/s41388-024-03028-x
PMCID:
PMC11164682
AbstractArticlePDF–6.3M
9.
Portrait of PTEN: Messages from mutant mice
Akira Suzuki, Toru Nakano, Tak Wah Mak, Takehiko Sasaki
Cancer Sci. 2008 Feb; 99(2): 209–213. Published online 2008 Jan 15. doi: 10.1111/j.1349-7006.2007.00670.x
PMCID:
PMC11158684
AbstractArticlePDF–188K
10.
Lineage-specific intolerance to oncogenic drivers restricts histological transformation
Eric E. Gardner, Ethan M. Earlie, Kate Li, Jerin Thomas, Melissa J. Hubisz, Benjamin D. Stein, Chen Zhang, Lewis C. Cantley, Ashley M. Laughney, Harold Varmus
Science. Author manuscript; available in PMC 2024 Jun 6.
Published in final edited form as: Science. 2024 Feb 9; 383(6683): eadj1415. Published online 2024 Feb 9. doi: 10.1126/science.adj1415
PMCID:
PMC11155264
AbstractArticlePDF–2.7M
11.
A miRNA-21-Mediated PTEN/Akt/NF-κB Axis Promotes Chronic Obstructive Pulmonary Disease Pathogenesis
Xiaoyan Sai, Chu Qin, Zixiao Zhang, Haoda Yu, Tao Bian
Int J Chron Obstruct Pulmon Dis. 2024; 19: 1141–1151. Published online 2024 May 25. doi: 10.2147/COPD.S453593
PMCID:
PMC11137736
AbstractArticlePDF–5.5M
12.
Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
Gemma Molinaro, Jacob E. Bowles, Katilynne Croom, Darya Gonzalez, Saba Mirjafary, Shari G. Birnbaum, Khaleel A. Razak, Jay R. Gibson, Kimberly M. Huber
Cell Rep. Author manuscript; available in PMC 2024 May 23.
Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114056. Published online 2024 Apr 5. doi: 10.1016/j.celrep.2024.114056
PMCID:
PMC11112681
AbstractArticlePDF–1.5M
13.
PTEN–GSK3β–MOB1 axis controls neurite outgrowth in vitro and in vivo
Zhiwen Song, Xiu Han, Hongjun Zou, Bin Zhang, Ya Ding, Xu Xu, Jian Zeng, Jinbo Liu, Aihua Gong
Cell Mol Life Sci. 2018 Dec; 75(23): 4445–4464. Published online 2018 Aug 1. doi: 10.1007/s00018-018-2890-0
PMCID:
PMC11105474
AbstractArticlePDF–4.0M
14.
The CRL4-DCAF13 ubiquitin E3 ligase supports oocyte meiotic resumption by targeting PTEN degradation
Jue Zhang, Yin-Li Zhang, Long-Wen Zhao, Shuai-Bo Pi, Song-Ying Zhang, Chao Tong, Heng-Yu Fan
Cell Mol Life Sci. 2020 Jun; 77(11): 2181–2197. Published online 2019 Sep 6. doi: 10.1007/s00018-019-03280-5
PMCID:
PMC11105099
AbstractArticlePDF–11M
15.
Parvalbumin interneuron activity in autism underlies susceptibility to PTSD-like memory formation
Alice Shaam Al Abed, Tiarne Vickie Allen, Noorya Yasmin Ahmed, Azza Sellami, Yovina Sontani, Elise Caitlin Rawlinson, Aline Marighetto, Aline Desmedt, Nathalie Dehorter
iScience. 2024 May 17; 27(5): 109747. Published online 2024 Apr 16. doi: 10.1016/j.isci.2024.109747
PMCID:
PMC11089364
AbstractArticlePDF–3.3M
16.
Noncovalently particle-anchored cytokines with prolonged tumor retention safely elicit potent antitumor immunity
Liqian Niu, Eungyo Jang, Ai Lin Chin, Ziyu Huo, Wenbo Wang, Wenjun Cai, Rong Tong
Sci Adv. 2024 Apr 19; 10(16): eadk7695. Published online 2024 Apr 19. doi: 10.1126/sciadv.adk7695
PMCID:
PMC11029804
AbstractArticlePDF–6.9M
17.
Overexpression of HMGB1 in hepatocytes accelerates PTEN inactivation-induced liver cancer
Dipti Athavale, Inés Barahona, Zhuolun Song, Romain Desert, Wei Chen, Hui Han, Sukanta Das, Xiaodong Ge, Sai Santosh B. Komakula, Shenglan Gao, Daniel Lantvit, Grace Guzman, Natalia Nieto
Hepatol Commun. 2023 Dec; 7(12): e0311. Published online 2023 Dec 7. doi: 10.1097/HC9.0000000000000311
PMCID:
PMC10984663
AbstractArticlePDF–1.8M
18.
Phosphatase and Tensin Homolog Inhibition in Proteolipid Protein 1-Expressing Cells Stimulates Neurogenesis and Gliogenesis in the Postnatal Enteric Nervous System
Crystal Woods, Amanda R. Flockton, Jaime Belkind-Gerson
Biomolecules. 2024 Mar; 14(3): 346. Published online 2024 Mar 13. doi: 10.3390/biom14030346
PMCID:
PMC10967813
AbstractArticlePDF–21M
19.
Hyperactivity of mTORC1- and mTORC2-dependent signaling mediates epilepsy downstream of somatic PTEN loss
Erin R Cullen, Mona Safari, Isabelle Mittelstadt, Matthew C Weston
eLife. 2024; 12: RP91323. Published online 2024 Mar 6. doi: 10.7554/eLife.91323
PMCID:
PMC10942640
AbstractArticlePDF–13M
20.
The mTOR pathway genes MTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function
Lena H Nguyen, Youfen Xu, Maanasi Nair, Angelique Bordey
eLife. 2024; 12: RP91010. Published online 2024 Feb 27. doi: 10.7554/eLife.91010
PMCID:
PMC10942629
AbstractArticlePDF–5.5M

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