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Items: 1 to 20 of 36

1.
A Homozygous Loss-of-Function Mutation in MSH5 Abolishes MutSγ Axial Loading and Causes Meiotic Arrest in NOA-Affected Individuals
Chenjia Gong, Tanveer Abbas, Zubair Muhammad, Jianteng Zhou, Ranjha Khan, Hui Ma, Huan Zhang, Qinghua Shi, Baolu Shi
Int J Mol Sci. 2022 Jun; 23(12): 6522. Published online 2022 Jun 10. doi: 10.3390/ijms23126522
PMCID:
PMC9224491
AbstractArticlePDF–7.7M
2.
Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing
Min Chen, Chencheng Yao, Yingying Qin, Xiuhong Cui, Peng Li, Zhiyong Ji, Limei Lin, Haowei Wu, Zhi Zhou, Yaoting Gui, Zheng Li, Fei Gao
Signal Transduct Target Ther. 2022; 7: 1. Published online 2022 Jan 3. doi: 10.1038/s41392-021-00710-4
PMCID:
PMC8724278
ArticlePDF–1.6M
3.
PCNA activates the MutLγ endonuclease to promote meiotic crossing over
Dhananjaya S. Kulkarni, Shannon N. Owens, Masayoshi Honda, Masaru Ito, Ye Yang, Mary W. Corrigan, Lan Chen, Aric L. Quan, Neil Hunter
Nature. Author manuscript; available in PMC 2021 Jul 16.
Published in final edited form as: Nature. 2020 Oct; 586(7830): 623–627. Published online 2020 Aug 19. doi: 10.1038/s41586-020-2645-6
Correction in:
Nature. 2021 Jan 19
PMCID:
PMC8284803
AbstractArticlePDF–4.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors
Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier
Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118
PMCID:
PMC8017720
AbstractArticlePDF–1.9M
6.
Long noncoding RNA HCP5 participates in premature ovarian insufficiency by transcriptionally regulating MSH5 and DNA damage repair via YB1
Xiaoyan Wang, Xinyue Zhang, Yujie Dang, Duan Li, Gang Lu, Wai-Yee Chan, Peter C K Leung, Shidou Zhao, Yingying Qin, Zi-Jiang Chen
Nucleic Acids Res. 2020 May 7; 48(8): 4480–4491. Published online 2020 Feb 29. doi: 10.1093/nar/gkaa127
PMCID:
PMC7192606
AbstractArticlePDF–3.3M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
11.
Mutations in MSH5 in primary ovarian insufficiency
Ting Guo, Shidou Zhao, Shigang Zhao, Min Chen, Guangyu Li, Xue Jiao, Zhao Wang, Yueran Zhao, Yingying Qin, Fei Gao, Zi-Jiang Chen
Hum Mol Genet. 2017 Apr 15; 26(8): 1452–1457. Published online 2017 Feb 8. doi: 10.1093/hmg/ddx044
PMCID:
PMC5393145
AbstractArticlePDF–615K
12.
HSP90 shapes the consequences of human genetic variation
Georgios I. Karras, Song Yi, Nidhi Sahni, Máté Fischer, Jenny Xie, Marc Vidal, Alan D. D'Andrea, Luke Whitesell, Susan Lindquist
Cell. Author manuscript; available in PMC 2018 Feb 23.
Published in final edited form as: Cell. 2017 Feb 23; 168(5): 856–866.e12. Published online 2017 Feb 16. doi: 10.1016/j.cell.2017.01.023
PMCID:
PMC5325763
AbstractArticlePDF–2.4M
13.
Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients
Jun-Yan Liu, Chen-Yue Qian, Yuan-Feng Gao, Juan Chen, Hong-Hao Zhou, Ji-Ye Yin
Chin J Cancer. 2017; 36: 12. Published online 2017 Jan 16. doi: 10.1186/s40880-016-0175-2
PMCID:
PMC5238520
AbstractArticlePDF–1.0M
14.
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning
Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich
eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466
PMCID:
PMC4764573
AbstractArticlePDF–5.7M
15.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
16.
hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ
Yang Xu, Xiling Wu, Chengtao Her
J Biol Chem. 2015 Jul 24; 290(30): 18545–18558. Published online 2015 Jun 8. doi: 10.1074/jbc.M115.642884
PMCID:
PMC4513114
AbstractArticlePDF–3.4M
17.
MutS Homologue hMSH5: Recombinational DSB Repair and Non-Synonymous Polymorphic Variants
Xiling Wu, Yang Xu, Katey Feng, Joshua D. Tompkins, Chengtao Her
PLoS One. 2013; 8(9): e73284. Published online 2013 Sep 4. doi: 10.1371/journal.pone.0073284
PMCID:
PMC3762724
AbstractArticlePDF–1.4M
18.
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
The International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), John B Harley, Marta E Alarcón-Riquelme, Lindsey A Criswell, Chaim O Jacob, Robert P Kimberly, Kathy L Moser, Betty P Tsao, Timothy J Vyse, Carl D Langefeld, Swapan K Nath, Joel M Guthridge, Beth L Cobb, Daniel B Mirel, Miranda C Marion, Adrienne H Williams, Jasmin Divers, Wei Wang, Summer G Frank, Bahram Namjou, Stacey B Gabriel, Annette T Lee, Peter K Gregersen, Timothy W Behrens, Kimberly E Taylor, Michelle Fernando, Raphael Zidovetzki, Patrick M Gaffney, Jeffrey C Edberg, John D Rioux, Joshua O Ojwang, Judith A James, Joan T Merrill, Gary S Gilkeson, Michael F Seldin, Hong Yin, Emily C Baechler, Quan-Zhen Li, Edward K Wakeland, Gail R Bruner, Kenneth M Kaufman, Jennifer A Kelly
Nat Genet. Author manuscript; available in PMC 2013 Jul 16.
Published in final edited form as: Nat Genet. 2008 Feb; 40(2): 204–210. Published online 2008 Jan 20. doi: 10.1038/ng.81
PMCID:
PMC3712260
AbstractArticlePDF–458K
19.
MutS homologue hMSH5: role in cisplatin-induced DNA damage response
Joshua D Tompkins, Xiling Wu, Chengtao Her
Mol Cancer. 2012; 11: 10. Published online 2012 Mar 8. doi: 10.1186/1476-4598-11-10
PMCID:
PMC3325843
AbstractArticlePDF–3.3M
20.
Biochemical and Computational Analysis Of LNX1 Interacting Proteins
Cheryl D. Wolting, Emily K. Griffiths, Renu Sarao, Brittany C. Prevost, Leanne E. Wybenga-Groot, C. Jane McGlade
PLoS One. 2011; 6(11): e26248. Published online 2011 Nov 8. doi: 10.1371/journal.pone.0026248
PMCID:
PMC3210812
AbstractArticlePDF–1.5M

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