PMC Links for GEO Profiles (Select 132540277) - PMC

Result Filters

Links from GEO Profiles

Items: 1 to 20 of 34

<< First< Prev

Page of 2

Select item 104498481.

Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13

Shenping Liu, Ruth F. Sommese, Nicole L. Nedoma, Lucy Mae Stevens, Jason K. Dutra, Liying Zhang, David J. Edmonds, Yang Wang, Michelle Garnsey, Michelle F. Clasquin

Nat Commun. 2023; 14: 5158. Published online 2023 Aug 24. doi: 10.1038/s41467-023-40766-0

PMCID:: PMC10449848

Abstract Article PDF–4.7M

Select item 101886542.

The protection conferred by HSD17B13 rs72613567 on hepatic fibrosis is likely mediated by lowering ballooning and portal inflammation

Eduardo Vilar-Gomez, Tiebing Liang, Katherine Yates, Laura Wilson, Rohit Loomba, Naga Chalasani

Clin Gastroenterol Hepatol. Author manuscript; available in PMC 2024 Oct 1.

Published in final edited form as: Clin Gastroenterol Hepatol. 2023 Oct; 21(11): 2981–2983.e3. Published online 2022 Nov 17. doi: 10.1016/j.cgh.2022.11.002

PMCID:: PMC10188654

Article PDF–512K

Select item 100339373.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 97816794.

MTARC1 and HSD17B13 Variants Have Protective Effects on Non-Alcoholic Fatty Liver Disease in Patients Undergoing Bariatric Surgery

Piotr Kalinowski, Wiktor Smyk, Małgorzata Nowosad, Rafał Paluszkiewicz, Łukasz Michałowski, Bogna Ziarkiewicz-Wróblewska, Susanne N. Weber, Piotr Milkiewicz, Frank Lammert, Krzysztof Zieniewicz, Marcin Krawczyk

Int J Mol Sci. 2022 Dec; 23(24): 15825. Published online 2022 Dec 13. doi: 10.3390/ijms232415825

PMCID:: PMC9781679

Abstract Article PDF–798K

Select item 95695815.

Impact of a Loss-of-Function Variant in HSD17B13 on Hepatic Decompensation and Mortality in Cirrhotic Patients

Antonio Gil-Gómez, Ángela Rojas, María R. García-Lozano, Rocío Muñoz-Hernández, Rocío Gallego-Durán, Douglas Maya-Miles, Rocío Montero-Vallejo, Sheila Gato, Javier Gallego, Rubén Francés, Germán Soriano, Javier Ampuero, Manuel Romero-Gómez

Int J Mol Sci. 2022 Oct; 23(19): 11840. Published online 2022 Oct 6. doi: 10.3390/ijms231911840

PMCID:: PMC9569581

Abstract Article PDF–1.2M

Select item 93151396.

Variants in mitochondrial amidoxime reducing component 1 and hydroxysteroid 17‐beta dehydrogenase 13 reduce severity of nonalcoholic fatty liver disease in children and suppress fibrotic pathways through distinct mechanisms

Christian A. Hudert, Leon A. Adams, Anna Alisi, Quentin M. Anstee, Annalisa Crudele, Laura G. Draijer, EU‐PNAFLD investigators, Samuel Furse, Jan G. Hengstler, Benjamin Jenkins, Kylie Karnebeek, Deirdre A. Kelly, Bart G. Koot, Albert Koulman, David Meierhofer, Phillip E. Melton, Trevor A. Mori, Stuart G. Snowden, Indra van Mourik, Anita Vreugdenhil, Susanna Wiegand, Jake P. Mann

Hepatol Commun. 2022 Aug; 6(8): 1934–1948. Published online 2022 Apr 11. doi: 10.1002/hep4.1955

PMCID:: PMC9315139

Abstract Article PDF–5.6M

Select item 86866347.

Association of HSD17B13 rs72613567: TA allelic variant with liver disease: review and meta-analysis

Shan Tang, Jing Zhang, Ting-Ting Mei, Wen-Yan Zhang, Su-Jun Zheng, Hai-Bin Yu

BMC Gastroenterol. 2021; 21: 490. Published online 2021 Dec 20. doi: 10.1186/s12876-021-02067-y

PMCID:: PMC8686634

Abstract Article PDF–1.4M

Select item 84372188.

The Protection Conferred by HSD17B13 rs72613567 Polymorphism on Risk of Steatohepatitis and Fibrosis May Be Limited to Selected Subgroups of Patients With NAFLD

Eduardo Vilar-Gomez, Carlos J. Pirola, Silvia Sookoian, Laura A. Wilson, Tiebing Liang, Naga Chalasani

Clin Transl Gastroenterol. 2021 Sep; 12(9): e00400. Published online 2021 Sep 10. doi: 10.14309/ctg.0000000000000400

PMCID:: PMC8437218

Abstract Article PDF–614K

Select item 83826449.

Combined effects of PNPLA3, TM6SF2 and HSD17B13 variants on severity of biopsy-proven non-alcoholic fatty liver disease

Rafael Paternostro, Katharina Staufer, Stefan Traussnigg, Albert-Friedrich Stättermayer, Emina Halilbasic, Omar Keritam, Elias L. Meyer, Judith Stift, Fritz Wrba, Bence Sipos, Ali Canbay, Martin Schlattjan, Elmar Aigner, Christian Datz, Felix Stickel, Clemens Schafmayer, Jochen Hampe, Stephan Buch, Gerhard Prager, Petra Munda, Mattias Mandorfer, Peter Ferenci, Michael Trauner

Hepatol Int. 2021 Aug; 15(4): 922–933. Published online 2021 Jun 2. doi: 10.1007/s12072-021-10200-y

PMCID:: PMC8382644

Abstract Article PDF–1.0M

Select item 827363510.

Loss-of-function HSD17B13 variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi-ethnic Asian cohort

Yi-Wen Ting, Amanda Shen-Yee Kong, Shamsul Mohd Zain, Wah-Kheong Chan, Hwa-Li Tan, Zahurin Mohamed, Yuh-Fen Pung, Rosmawati Mohamed

Clin Mol Hepatol. 2021 Jul; 27(3): 486–498. Published online 2021 Feb 23. doi: 10.3350/cmh.2020.0162

PMCID:: PMC8273635

Abstract Article PDF–673K

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 752060912.

Pediatric non-alcoholic fatty liver disease and kidney function: Effect of HSD17B13 variant

Anna Di Sessa, Giuseppina Rosaria Umano, Grazia Cirillo, Antonio Paride Passaro, Valentina Verde, Domenico Cozzolino, Stefano Guarino, Pierluigi Marzuillo, Emanuele Miraglia del Giudice

World J Gastroenterol. 2020 Sep 28; 26(36): 5474–5483. Published online 2020 Sep 28. doi: 10.3748/wjg.v26.i36.5474

PMCID:: PMC7520609

Abstract Article PDF–1.0M

Select item 733419713.

The mutational constraint spectrum quantified from variation in 141,456 humans

Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo Wang, Ryan L. Collins, Kristen M. Laricchia, Andrea Ganna, Daniel P. Birnbaum, Laura D. Gauthier, Harrison Brand, Matthew Solomonson, Nicholas A. Watts, Daniel Rhodes, Moriel Singer-Berk, Eleina M. England, Eleanor G. Seaby, Jack A. Kosmicki, Raymond K. Walters, Katherine Tashman, Yossi Farjoun, Eric Banks, Timothy Poterba, Arcturus Wang, Cotton Seed, Nicola Whiffin, Jessica X. Chong, Kaitlin E. Samocha, Emma Pierce-Hoffman, Zachary Zappala, Anne H. O’Donnell-Luria, Eric Vallabh Minikel, Ben Weisburd, Monkol Lek, James S. Ware, Christopher Vittal, Irina M. Armean, Louis Bergelson, Kristian Cibulskis, Kristen M. Connolly, Miguel Covarrubias, Stacey Donnelly, Steven Ferriera, Stacey Gabriel, Jeff Gentry, Namrata Gupta, Thibault Jeandet, Diane Kaplan, Christopher Llanwarne, Ruchi Munshi, Sam Novod, Nikelle Petrillo, David Roazen, Valentin Ruano-Rubio, Andrea Saltzman, Molly Schleicher, Jose Soto, Kathleen Tibbetts, Charlotte Tolonen, Gordon Wade, Michael E. Talkowski, Genome Aggregation Database Consortium, Benjamin M. Neale, Mark J. Daly, Daniel G. MacArthur

Nature. 2020; 581(7809): 434–443. Published online 2020 May 27. doi: 10.1038/s41586-020-2308-7

Correction in:: Nature. 2021; 590(7846): E53.

PMCID:: PMC7334197

Abstract Article PDF–3.1M

Select item 730679214.

Common homozygosity for predicted loss-of-function variants reveals both redundant and advantageous effects of dispensable human genes

Antonio Rausell, Yufei Luo, Marie Lopez, Yoann Seeleuthner, Franck Rapaport, Antoine Favier, Peter D. Stenson, David N. Cooper, Etienne Patin, Jean-Laurent Casanova, Lluis Quintana-Murci, Laurent Abel

Proc Natl Acad Sci U S A. 2020 Jun 16; 117(24): 13626–13636. Published online 2020 Jun 2. doi: 10.1073/pnas.1917993117

PMCID:: PMC7306792

Abstract Article PDF–1.0M

Select item 727895615.

Genetic Susceptibility to Chronic Liver Disease in Individuals from Pakistan

Asad Mehmood Raja, Ester Ciociola, Imran Nazir Ahmad, Faisal Saud Dar, Syed Muhammad Saqlan Naqvi, Muhammad Moaeen-ud-Din, Ghazala Kaukab Raja, Stefano Romeo, Rosellina Margherita Mancina

Int J Mol Sci. 2020 May; 21(10): 3558. Published online 2020 May 18. doi: 10.3390/ijms21103558

PMCID:: PMC7278956

Abstract Article PDF–560K

Select item 716998316.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 700397317.

Impact of HSD17B13 rs72613567 genotype on hepatic decompensation and mortality in patients with portal hypertension

Bernhard Scheiner, Albert F. Stättermayer, Philipp Schwabl, Theresa Bucsics, Rafael Paternostro, David Bauer, Benedikt Simbrunner, Ralf Schmidt, Rodrig Marculescu, Arnulf Ferlitsch, Markus Peck‐Radosavljevic, Mathias Pinter, Michael Trauner, Thomas Reiberger, Peter Ferenci, Mattias Mandorfer

Liver Int. 2020 Feb; 40(2): 393–404. Published online 2019 Dec 3. doi: 10.1111/liv.14304

PMCID:: PMC7003973

Abstract Article PDF–1.1M

Select item 666803318.

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease

N.S. Abul-Husn, X. Cheng, A.H. Li, Y. Xin, C. Schurmann, P. Stevis, Y. Liu, J. Kozlitina, S. Stender, G.C. Wood, A.N. Stepanchick, M.D. Still, S. McCarthy, C. O’Dushlaine, J.S. Packer, S. Balasubramanian, N. Gosalia, D. Esopi, S.Y. Kim, S. Mukherjee, A.E. Lopez, E.D. Fuller, J. Penn, X. Chu, J.Z. Luo, U.L. Mirshahi, D.J. Carey, C.D. Still, M.D. Feldman, A. Small, S.M. Damrauer, D.J. Rader, B. Zambrowicz, W. Olson, A.J. Murphy, I.B. Borecki, A.R. Shuldiner, J.G. Reid, J.D. Overton, G.D. Yancopoulos, H.H. Hobbs, J.C. Cohen, O. Gottesman, T.M. Teslovich, A. Baras, T. Mirshahi, J. Gromada, F.E. Dewey

N Engl J Med. Author manuscript; available in PMC 2019 Jul 31.

Published in final edited form as: N Engl J Med. 2018 Mar 22; 378(12): 1096–1106. doi: 10.1056/NEJMoa1712191

PMCID:: PMC6668033

Abstract Article PDF–1.4M

Select item 643873719.

HSD17B13 is a Hepatic Retinol Dehydrogenase Associated with Histological Features of Non-Alcoholic Fatty Liver Disease

Yanling Ma, Olga V. Belyaeva, Philip M. Brown, Koji Fujita, Katherine Valles, Suman Karki, Ynto S. de Boer, Christopher Koh, Yanhua Chen, Xiaomeng Du, Samuel K. Handelman, Vincent Chen, Elizabeth K. Speliotes, Cara Nestlerode, Emmanuel Thomas, David E. Kleiner, Joseph M. Zmuda, Arun J. Sanyal, Natalia Y. Kedishvili, T Jake Liang, Yaron Rotman, NASH CRN

Hepatology. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Hepatology. 2019 Apr; 69(4): 1504–1519. Published online 2019 Mar 5. doi: 10.1002/hep.30350