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Select item 110897011.

N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension

Kang Kang, Jingjing Xiang, Xingshi Zhang, Yuting Xie, Mengting Zhou, Le Zeng, Junhao Zhuang, Jiahao Kuang, Yuanyuan Lin, Bozhe Hu, Qianmin Xiong, Qing Yin, Qiang Su, Xiaoyun Liao, Jun Wang, Yanqin Niu, Cuilian Liu, Jinglin Tian, Deming Gou

Cell Mol Biol Lett. 2024; 29: 69. Published online 2024 May 13. doi: 10.1186/s11658-024-00590-w

PMCID:: PMC11089701

Abstract Article PDF–1.5M

Select item 102132212.

Krüppel-like factor 2: a central regulator of B cell differentiation and plasma cell homing

Jens Wittner, Wolfgang Schuh

Front Immunol. 2023; 14: 1172641. Published online 2023 May 12. doi: 10.3389/fimmu.2023.1172641

PMCID:: PMC10213221

Abstract Article PDF–7.8M

Select item 99849573.

Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expression

Jihyun Song, Soo Jin Kim, Jahnavi Gollamudi, Perumal Thiagarajan, Josef T. Prchal

Blood Adv. 2023 Mar 14; 7(5): 712–717. Published online 2022 Nov 8. doi: 10.1182/bloodadvances.2022008052

PMCID:: PMC9984957

Abstract Article PDF–376K

Select item 99813134.

Circ_0043256 upregulates KLF2 expression by absorbing miR‐1206 to suppress the tumorigenesis of lung cancer

Ying Zhou, Hongliu Liu, Rui Wang, Mingtao Zhang

Thorac Cancer. 2023 Mar; 14(7): 683–699. Published online 2023 Jan 21. doi: 10.1111/1759-7714.14794

PMCID:: PMC9981313

Abstract Article PDF–9.4M

Select item 99169095.

Dysregulation of Krüppel-like Factor 2 and Myocyte Enhancer Factor 2D Drive Cardiac Microvascular Inflammation and Dysfunction in Diabetes

Mostafa Samak, Andreas Kues, Diana Kaltenborn, Lina Klösener, Matthias Mietsch, Giulia Germena, Rabea Hinkel

Int J Mol Sci. 2023 Feb; 24(3): 2482. Published online 2023 Jan 27. doi: 10.3390/ijms24032482

Correction in:: Int J Mol Sci. 2024 Jan; 25(2): 1058.

PMCID:: PMC9916909

Abstract Article PDF–3.0M

Select item 98627106.

Down-regulation of KLF2 in lung fibroblasts is linked with COVID-19 immunofibrosis and restored by combined inhibition of NETs, JAK-1/2 and IL-6 signaling

Akrivi Chrysanthopoulou, Christina Antoniadou, Anastasia-Maria Natsi, Efstratios Gavriilidis, Vasileios Papadopoulos, Evangelia Xingi, Stylianos Didaskalou, Dimitrios Mikroulis, Victoria Tsironidou, Konstantinos Kambas, Maria Koffa, Panagiotis Skendros, Konstantinos Ritis

Clin Immunol. 2023 Feb; 247: 109240. Published online 2023 Jan 21. doi: 10.1016/j.clim.2023.109240

PMCID:: PMC9862710

Abstract Article PDF–4.0M

Select item 97163117.

Heterozygous premature termination in zinc-finger domain of Krüppel-like factor 2 gene associates with dysregulated immunity

Nora Pernaa, Salla Keskitalo, Iftekhar Chowdhury, Antti Nissinen, Virpi Glumoff, Riikka Keski-Filppula, Juhani Junttila, Kari K. Eklund, Wenny Santaniemi, Sanna Siitonen, Mikko RJ. Seppänen, Paula Vähäsalo, Markku Varjosalo, Pirjo Åström, Timo Hautala

Front Immunol. 2022; 13: 819929. Published online 2022 Nov 18. doi: 10.3389/fimmu.2022.819929

PMCID:: PMC9716311

Abstract Article PDF–6.5M

Select item 96263488.

miR‐92a‐3p promotes breast cancer proliferation by regulating the KLF2/BIRC5 axis

Zhi‐Hao Yu, Zhao‐Hui Chen, Guang‐Lei Zhou, Xue‐Jie Zhou, Hai‐Yan Ma, Yue Yu, Xin Wang, Xu‐Chen Cao

Thorac Cancer. 2022 Nov; 13(21): 2992–3000. Published online 2022 Sep 13. doi: 10.1111/1759-7714.14648

PMCID:: PMC9626348

Abstract Article PDF–2.0M

Select item 94925549.

Relation among EGFL7, ITGB3, and KLF2 and their clinical implication in multiple myeloma patients: a prospective study

Yaqiong Li, Lingli Zhang, Jichang Gong

Ir J Med Sci. 2022; 191(5): 1995–2001. Published online 2021 Oct 11. doi: 10.1007/s11845-021-02781-2

PMCID:: PMC9492554

Abstract Article PDF–1.1M

Select item 946834610.

Long non-coding RNA SNHG1 promotes bladder cancer progression by upregulating EZH2 and repressing KLF2 transcription

Jie Min, Jiaxing Ma, Qi Wang, Dexin Yu

Clinics (Sao Paulo) 2022 Jan-Dec; 77: 100081. Published online 2022 Sep 7. doi: 10.1016/j.clinsp.2022.100081

PMCID:: PMC9468346

Abstract Article PDF–2.1M

Select item 934562111.

KLF2-induced circZKSCAN1 potentiates the tumorigenic properties of clear cell renal cell carcinoma by targeting the miR-1294/PIM1 axis

Mingzi Li, Mingxun Zhang, Muling Chen, Jiantao Xiao, Xingyu Mu, Jingtao Peng, Jie Fan

Cell Cycle. 2022; 21(13): 1376–1390. Published online 2022 Mar 14. doi: 10.1080/15384101.2022.2051293

PMCID:: PMC9345621

Abstract Article PDF–3.9M

Select item 850897912.

Cilostazol Induces eNOS and TM Expression via Activation with Sirtuin 1/Krüppel-like Factor 2 Pathway in Endothelial Cells

Chih-Hsien Wu, Yi-Lin Chiu, Chung-Yueh Hsieh, Guo-Shiang Tsung, Lian-Shan Wu, Cheng-Chung Cheng, Tsung-Neng Tsai

Int J Mol Sci. 2021 Oct; 22(19): 10287. Published online 2021 Sep 24. doi: 10.3390/ijms221910287

PMCID:: PMC8508979

Abstract Article PDF–5.0M

Select item 842636713.

Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer

Zijian Ma, Ke Wei, Fengming Yang, Zizhang Guo, Chunfeng Pan, Yaozhou He, Jun Wang, Zhihua Li, Liang Chen, YiJiang Chen, Yang Xia

Cell Death Dis. 2021 Sep; 12(9): 840. Published online 2021 Sep 8. doi: 10.1038/s41419-021-04037-4

PMCID:: PMC8426367

Abstract Article PDF–8.6M

Select item 839957214.

SARS-CoV-2 Infection Is Associated with Reduced Krüppel-like Factor 2 in Human Lung Autopsy

David Wu, Tzu-Han Lee, Ru-Ting Huang, Robert D. Guzy, Nathan Schoettler, Ayodeji Adegunsoye, Jeffrey Mueller, Aliya Husain, Anne I. Sperling, Gökhan M. Mutlu, Yun Fang

Am J Respir Cell Mol Biol. 2021 Aug; 65(2): 222–226. Published online 2021 Mar 30. doi: 10.1165/rcmb.2020-0564LE

PMCID:: PMC8399572

Article PDF–1.6M

Select item 827337115.

The zinc finger transcription factor, KLF2, protects against COVID-19 associated endothelial dysfunction

Suowen Xu, Yujie Liu, Yu Ding, Sihui Luo, Xueying Zheng, Xiumei Wu, Zhenghong Liu, Iqra Ilyas, Suyu Chen, Shuxin Han, Peter J. Little, Mukesh K. Jain, Jianping Weng

Signal Transduct Target Ther. 2021; 6: 266. Published online 2021 Jul 12. doi: 10.1038/s41392-021-00690-5

PMCID:: PMC8273371

Abstract Article PDF–2.5M

Select item 800904816.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 753940317.

Epigenetic silencing of KLF2 by long non-coding RNA SNHG1 inhibits periodontal ligament stem cell osteogenesis differentiation

Zhaobao Li, Xiangjun Guo, Shuainan Wu

Stem Cell Res Ther. 2020; 11: 435. Published online 2020 Oct 7. doi: 10.1186/s13287-020-01953-8

PMCID:: PMC7539403

Abstract Article PDF–2.4M

Select item 753464118.

Temporal activation of LRH‐1 and RAR‐γ in human pluripotent stem cells induces a functional naïve‐like state

Adeleh Taei, Tahereh Kiani, Zeinab Taghizadeh, Sharif Moradi, Azam Samadian, Sepideh Mollamohammadi, Ali Sharifi‐Zarchi, Stefan Guenther, Azimeh Akhlaghpour, Behrouz Asgari Abibeiglou, Mostafa Najar‐Asl, Razieh Karamzadeh, Keynoosh Khalooghi, Thomas Braun, Seyedeh‐Nafiseh Hassani, Hossein Baharvand

EMBO Rep. 2020 Oct 5; 21(10): e47533. Published online 2020 Aug 16. doi: 10.15252/embr.201847533