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Select item 106194911.

SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A

Ruicai Gu, Tae-Dong Kim, Hoogeun Song, Yuan Sui, Sook Shin, Sangphil Oh, Ralf Janknecht

JCI Insight. 2023 Oct 23; 8(20): e164990. Published online 2023 Oct 23. doi: 10.1172/jci.insight.164990

PMCID:: PMC10619491

Abstract Article PDF–2.5M

Select item 104097592.

Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1

Yiming Hou, Wenqian Yu, Gaoyi Wu, Zhaoling Wang, Shuai Leng, Ming Dong, Na Li, Lei Chen

Cell Death Dis. 2023 Aug; 14(8): 510. Published online 2023 Aug 8. doi: 10.1038/s41419-023-06024-3

PMCID:: PMC10409759

Abstract Article PDF–5.4M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101826544.

The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase

Eva Monte-Serrano, Patricia Morejón-García, Ignacio Campillo-Marcos, Aurora Campos-Díaz, Elena Navarro-Carrasco, Pedro A. Lazo

Epigenetics Chromatin. 2023; 16: 18. Published online 2023 May 13. doi: 10.1186/s13072-023-00494-7

PMCID:: PMC10182654

Abstract Article PDF–3.1M

Select item 101708015.

JMJD2A participates in cytoskeletal remodeling to regulate castration-resistant prostate cancer docetaxel resistance

Xiang Cai, Xi Duan, Tielong Tang, Shu Cui, Tao Wu

BMC Cancer. 2023; 23: 423. Published online 2023 May 10. doi: 10.1186/s12885-023-10915-1

PMCID:: PMC10170801

Abstract Article PDF–4.6M

Select item 99224686.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 97419677.

DDX24 promotes metastasis by regulating RPL5 in non‐small cell lung cancer

Xinyan Hu, Fangfang Li, Yulan Zhou, Hairun Gan, Tiancheng Wang, Luting Li, Haoyu Long, Bing Li, Pengfei Pang

Cancer Med. 2022 Dec; 11(23): 4513–4525. Published online 2022 Jul 21. doi: 10.1002/cam4.4835

PMCID:: PMC9741967

Abstract Article PDF–25M

Select item 95403458.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 94004939.

SUMO Modification of Histone Demethylase KDM4A in Kaposi’s Sarcoma-Associated Herpesvirus-Induced Primary Effusion Lymphoma

Wayne W. Yeh, Yin-Quan Chen, Wan-Shan Yang, Yung-Chih Hong, Sen Kao, Tze-Tze Liu, Ting-Wen Chen, Lung Chang, Pei-Ching Chang

J Virol. 2022 Aug; 96(16): e00755-22. Published online 2022 Aug 1. doi: 10.1128/jvi.00755-22

PMCID:: PMC9400493

Abstract Article PDF–5.1M

Select item 934857610.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 923977711.

Investigation of the Mechanism of hsa_circ_000 1429 Adsorbed miR-205 to Regulate KDM4A and Promote Breast Cancer Metastasis

Yuting Xu, Cheng Qian, Chunxiao Liu, Yingqiang Fu, Kaiyuan Zhu, Zhenbo Niu, Jiaxin Liu

Contrast Media Mol Imaging. 2022; 2022: 4657952. Published online 2022 Jun 21. doi: 10.1155/2022/4657952

PMCID:: PMC9239777

Abstract Article PDF–2.7M

Select item 911973612.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 889702213.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 852131714.

Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation

Jialiang Shao, Tiezhu Shi, Hua Yu, Yufeng Ding, Liping Li, Xiang Wang, Xiongjun Wang

EMBO J. 2021 Oct 18; 40(20): e107480. Published online 2021 Jul 16. doi: 10.15252/embj.2020107480

Correction in:: EMBO J. 2022 Jan 17; 41(2): e110306.

PMCID:: PMC8521317

Abstract Article PDF–3.6M

Select item 841729515.

Histone demethylase KDM4A plays an oncogenic role in nasopharyngeal carcinoma by promoting cell migration and invasion

Jingyi Zhao, Bingyan Li, Yongxia Ren, Tiansong Liang, Juan Wang, Suna Zhai, Xiqian Zhang, Pengcheng Zhou, Xiangxian Zhang, Yuanyuan Pan, Fangfang Gao, Sulan Zhang, Liming Li, Yongqiang Yang, Xiaoyu Deng, Xiaole Li, Linhui Chen, Daoke Yang, Yingjuan Zheng

Exp Mol Med. 2021 Aug; 53(8): 1207–1217. Published online 2021 Aug 12. doi: 10.1038/s12276-021-00657-0

PMCID:: PMC8417295

Abstract Article PDF–1.9M

Select item 836800416.

Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM)

Moshe Lapidot, Abigail E. Case, Ellen L. Weisberg, Chengcheng Meng, Sarah R. Walker, Swati Garg, Wei Ni, Klaus Podar, Yin P. Hung, Ruben D. Carrasco, Aine Knott, Prafulla C. Gokhale, Sunil Sharma, Alex Pozhitkov, Prakash Kulkarni, David A. Frank, Ravi Salgia, James D. Griffin, Srinivas V. Saladi, Raphael Bueno, Martin Sattler

Br J Cancer. 2021 Aug 17; 125(4): 582–592. Published online 2021 Jun 4. doi: 10.1038/s41416-021-01441-7

PMCID:: PMC8368004

Abstract Article PDF–1.8M

Select item 821916917.

Long non-coding RNA KIKAT/LINC01061 as a novel epigenetic regulator that relocates KDM4A on chromatin and modulates viral reactivation

Wan-Shan Yang, Wayne W. Yeh, Mel Campbell, Lung Chang, Pei-Ching Chang

PLoS Pathog. 2021 Jun; 17(6): e1009670. Published online 2021 Jun 10. doi: 10.1371/journal.ppat.1009670

PMCID:: PMC8219169

Abstract Article PDF–3.6M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 814101819.

Targeting KDM4A Epigenetically Activates Tumor Cell-intrinsic Immunity by Inducing DNA Replication Stress

Wuchang Zhang, Wei Liu, Lingfei Jia, Demeng Chen, Insoon Chang, Michael Lake, Laurent A. Bentolila, Cun-Yu Wang

Mol Cell. Author manuscript; available in PMC 2022 May 20.

Published in final edited form as: Mol Cell. 2021 May 20; 81(10): 2148–2165.e9. Published online 2021 Mar 19. doi: 10.1016/j.molcel.2021.02.038

PMCID:: PMC8141018

Abstract Article PDF–2.0M

Select item 813451920.

KDM4A regulates myogenesis by demethylating H3K9me3 of myogenic regulatory factors

Qi Zhu, Feng Liang, Shufang Cai, Xiaorong Luo, Tianqi Duo, Ziyun Liang, Zuyong He, Yaosheng Chen, Delin Mo

Cell Death Dis. 2021 Jun; 12(6): 514. Published online 2021 May 19. doi: 10.1038/s41419-021-03799-1

PMCID:: PMC8134519

Abstract Article PDF–6.9M

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