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Items: 1 to 20 of 36

1.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
2.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
3.
HOXB13 suppresses proliferation, migration and invasion, and promotes apoptosis of gastric cancer cells through transcriptional activation of VGLL4 to inhibit the involvement of TEAD4 in the Hippo signaling pathway
Hui Geng, Guangli Liu, Jiandong Hu, Jianchao Li, Dong Wang, Shenshan Zou, Xintao Xu
Mol Med Rep. 2021 Oct; 24(4): 722. Published online 2021 Aug 11. doi: 10.3892/mmr.2021.12361
PMCID:
PMC8383034
AbstractArticlePDF–15M
4.
Biochemical properties of VGLL4 from Homo sapiens and Tgi from Drosophila melanogaster and possible biological implications
Yannick Mesrouze, Marco Meyerhofer, Catherine Zimmermann, Patrizia Fontana, Dirk Erdmann, Patrick Chène
Protein Sci. 2021 Sep; 30(9): 1871–1881. Published online 2021 Jun 8. doi: 10.1002/pro.4138
PMCID:
PMC8376407
AbstractArticlePDF–2.3M
5.
VGLL4 inhibits YAP1/TEAD signaling to suppress the epidermal squamous cell carcinoma cancer phenotype
McKayla Mickle, Gautam Adhikary, Suruchi Shrestha, Wen Xu, Richard L. Eckert
Mol Carcinog. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Mol Carcinog. 2021 Jul; 60(7): 497–507. Published online 2021 May 18. doi: 10.1002/mc.23307
PMCID:
PMC8243851
AbstractArticlePDF–3.0M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
VGLL4 interacts with STAT3 to function as a tumor suppressor in triple-negative breast cancer
Hongming Song, Qifeng Luo, Xiaochong Deng, Changle Ji, Dengfeng Li, Amik Munankarmy, Wei Jian, Junyong Zhao, Lin Fang
Exp Mol Med. 2019 Nov; 51(11): 141. Published online 2019 Nov 20. doi: 10.1038/s12276-019-0338-8
PMCID:
PMC6868227
AbstractArticlePDF–2.4M
9.
Down‐regulation of interferon regulatory factor 2 binding protein 2 suppresses gastric cancer progression by negatively regulating connective tissue growth factor
Yangyang Yao, Yi Wang, Li Li, Xiaojun Xiang, Junhe Li, Jun Chen, Zhen Liu, Shanshan Huang, Jianping Xiong, Jun Deng
J Cell Mol Med. 2019 Dec; 23(12): 8076–8089. Published online 2019 Sep 27. doi: 10.1111/jcmm.14677
PMCID:
PMC6851004
AbstractArticlePDF–2.1M
10.
Loss of VGLL4 suppresses tumor PD‐L1 expression and immune evasion
Ailing Wu, Qingzhe Wu, Yujie Deng, Yuning Liu, Jinqiu Lu, Liansheng Liu, Xiaoling Li, Cheng Liao, Bin Zhao, Hai Song
EMBO J. 2019 Jan 3; 38(1): e99506. Published online 2018 Nov 5. doi: 10.15252/embj.201899506
PMCID:
PMC6589543
AbstractArticlePDF–1.5M
11.
Validation of Osteogenic Properties of Cytochalasin D by High-Resolution RNA-Sequencing in Mesenchymal Stem Cells Derived from Bone Marrow and Adipose Tissues
Rebekah M. Samsonraj, Christopher R. Paradise, Amel Dudakovic, Buer Sen, Asha A. Nair, Allan B. Dietz, David R. Deyle, Simon M. Cool, Janet Rubin, Andre J. van Wijnen
Stem Cells Dev. 2018 Aug 15; 27(16): 1136–1145. Published online 2018 Aug 15. doi: 10.1089/scd.2018.0037
PMCID:
PMC6096350
AbstractArticlePDF–1.6M
12.
Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins
James E. Tomkins, Sybille Dihanich, Alexandra Beilina, Raffaele Ferrari, Nicolò Ilacqua, Mark R. Cookson, Patrick A. Lewis, Claudia Manzoni
Proteomics. 2018 May; 18(10): 1700444. Published online 2018 Apr 17. doi: 10.1002/pmic.201700444
PMCID:
PMC5992104
AbstractArticlePDF–1.2M
13.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
14.
Cyclin-dependent kinase 1 (CDK1)-mediated mitotic phosphorylation of the transcriptional co-repressor Vgll4 inhibits its tumor-suppressing activity
Yongji Zeng, Seth Stauffer, Jiuli Zhou, Xingcheng Chen, Yuanhong Chen, Jixin Dong
J Biol Chem. 2017 Sep 8; 292(36): 15028–15038. Published online 2017 Jul 24. doi: 10.1074/jbc.M117.796284
PMCID:
PMC5592678
AbstractArticlePDF–3.9M
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer
Yinglong Zhang, He Shen, Henry G. Withers, Nuo Yang, Kayla E. Denson, Ashley L. Mussell, Alexander Truskinovsky, Qingyu Fan, Irwin H. Gelman, Costa Frangou, Jianmin Zhang
Sci Rep. 2017; 7: 6190. Published online 2017 Jul 21. doi: 10.1038/s41598-017-06227-7
PMCID:
PMC5522454
AbstractArticlePDF–7.1M
17.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
18.
VGLL4 targets a TCF4–TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer
Shi Jiao, Chuanchuan Li, Qian Hao, Haofei Miao, Lei Zhang, Lin Li, Zhaocai Zhou
Nat Commun. 2017; 8: 14058. Published online 2017 Jan 4. doi: 10.1038/ncomms14058
PMCID:
PMC5216127
AbstractArticlePDF–2.0M
19.
Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein
Encheng Zhang, Bing Shen, Xingyu Mu, Yan Qin, Fang Zhang, Yong Liu, Jiantao Xiao, Pingzhao Zhang, Chenji Wang, Mingyue Tan, Yu Fan
Am J Cancer Res. 2016; 6(12): 2901–2909. Published online 2016 Dec 1.
PMCID:
PMC5199763
AbstractArticlePDF–1.1M
20.
Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia
A Ingason, I Giegling, A M Hartmann, J Genius, B Konte, M Friedl, Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC), S Ripke, P F Sullivan, D St. Clair, D A Collier, M C O'Donovan, K Mirnics, D Rujescu
Transl Psychiatry. 2015 Oct; 5(10): e656. Published online 2015 Oct 13. doi: 10.1038/tp.2015.151
PMCID:
PMC4930128
AbstractArticlePDF–519K

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