PMC Links for GEO Profiles (Select 132595794) - PMC

Jeong Han Lee, Maria C. Perez-Flores, Seojin Park, Hyo Jeong Kim, Yingying Chen, Mincheol Kang, Jennifer Kersigo, Jinsil Choi, Phung N. Thai, Ryan L. Woltz, Dolores Columba Perez-Flores, Guy Perkins, Choong-Ryoul Sihn, Pauline Trinh, Xiao-Dong Zhang, Padmini Sirish, Yao Dong, Wayne Wei Feng, Isaac N. Pessah, Rose E. Dixon, Bernd Sokolowski, Bernd Fritzsch, Nipavan Chiamvimonvat, Ebenezer N. Yamoah

Nat Commun. 2024; 15: 526. Published online 2024 Jan 16. doi: 10.1038/s41467-023-44230-x

PMCID:: PMC10791687

Abstract Article PDF–5.3M

Select item 101473774.

Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

Michelle M Frank, Austen A Sitko, Kirupa Suthakar, Lester Torres Cadenas, Mackenzie Hunt, Mary Caroline Yuk, Catherine JC Weisz, Lisa V Goodrich

eLife. 2023; 12: e83855. Published online 2023 Mar 6. doi: 10.7554/eLife.83855

PMCID:: PMC10147377

Abstract Article PDF–24M

Select item 95648235.

The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells

Robert Fettiplace, David N. Furness, Maryline Beurg

Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2210849119. Published online 2022 Oct 3. doi: 10.1073/pnas.2210849119

PMCID:: PMC9564823

Abstract Article PDF–2.0M

Select item 93487956.

Regulation of membrane homeostasis by TMC1 mechanoelectrical transduction channels is essential for hearing

Angela Ballesteros, Kenton J. Swartz

Sci Adv. 2022 Aug; 8(31): eabm5550. Published online 2022 Aug 3. doi: 10.1126/sciadv.abm5550

PMCID:: PMC9348795

Abstract Article PDF–20M

Select item 92788707.

Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices

Nurunisa Akyuz, K. Domenica Karavitaki, Bifeng Pan, Panos I. Tamvakologos, Kelly P. Brock, Yaqiao Li, Debora S. Marks, David P. Corey

Sci Adv. 2022 Jul; 8(28): eabo1126. Published online 2022 Jul 13. doi: 10.1126/sciadv.abo1126

PMCID:: PMC9278870

Abstract Article PDF–2.6M

Select item 92503578.

Ca²⁺ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips

Julia Halford, Michael Bateschell, Peter G. Barr-Gillespie

Mol Biol Cell. 2022 Apr 1; 33(4): br6. Published online 2022 Mar 29. doi: 10.1091/mbc.E21-10-0491

PMCID:: PMC9250357

Abstract Article PDF–14M

Select item 85981589.

Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses

John Lee, Kosuke Kawai, Jeffrey R Holt, Gwenaëlle SG Géléoc

eLife. 2021; 10: e69433. Published online 2021 Nov 4. doi: 10.7554/eLife.69433

PMCID:: PMC8598158

Abstract Article PDF–5.0M

Select item 838380810.

The speed of the hair cell mechanotransducer channel revealed by fluctuation analysis

Maryline Beurg, Jong-Hoon Nam, Robert Fettiplace

J Gen Physiol. 2021 Oct 4; 153(10): e202112959. Published online 2021 Aug 19. doi: 10.1085/jgp.202112959

PMCID:: PMC8383808

Abstract Article PDF–3.2M

Select item 837495911.

CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells

Xiaoping Liang, Xufeng Qiu, Gilman Dionne, Christopher L. Cunningham, Michele L. Pucak, Guihong Peng, Ye-Hyun Kim, Amanda Lauer, Lawrence Shapiro, Ulrich Müller

Neuron. Author manuscript; available in PMC 2022 Jul 7.

Published in final edited form as: Neuron. 2021 Jul 7; 109(13): 2131–2149.e15. Published online 2021 Jun 5. doi: 10.1016/j.neuron.2021.05.007

PMCID:: PMC8374959

Abstract Article PDF–3.9M

Select item 815260712.

New Tmc1 Deafness Mutations Impact Mechanotransduction in Auditory Hair Cells

Maryline Beurg, Lisa A. Schimmenti, Alaa Koleilat, Sami S. Amr, Andrea Oza, Amanda J. Barlow, Angela Ballesteros, Robert Fettiplace

J Neurosci. 2021 May 19; 41(20): 4378–4391. doi: 10.1523/JNEUROSCI.2537-20.2021

PMCID:: PMC8152607

Abstract Article PDF–4.6M

Select item 788059813.

Early peripheral activity alters nascent subplate circuits in the auditory cortex

Xiangying Meng, Didhiti Mukherjee, Joseph P. Y. Kao, Patrick O. Kanold

Sci Adv. 2021 Feb; 7(7): eabc9155. Published online 2021 Feb 12. doi: 10.1126/sciadv.abc9155

PMCID:: PMC7880598

Abstract Article PDF–4.2M

Select item 735159914.

TMIE defines pore and gating properties of the mechanotransduction channel of mammalian cochlear hair cells

Christopher L. Cunningham, Xufeng Qiu, Zizhen Wu, Bo Zhao, Guihong Peng, Ye-Hyun Kim, Amanda Lauer, Ulrich Müller

Neuron. Author manuscript; available in PMC 2021 Jul 8.

Published in final edited form as: Neuron. 2020 Jul 8; 107(1): 126–143.e8. Published online 2020 Apr 27. doi: 10.1016/j.neuron.2020.03.033

PMCID:: PMC7351599

Abstract Article PDF–3.5M

Select item 729870015.

Tmc gene therapy restores auditory function in deaf mice

Charles Askew, Cylia Rochat, Bifeng Pan, Yukako Asai, Hena Ahmed, Erin Child, Bernard L. Schneider, Patrick Aebischer, Jeffrey R. Holt

Sci Transl Med. Author manuscript; available in PMC 2020 Jun 17.

Published in final edited form as: Sci Transl Med. 2015 Jul 8; 7(295): 295ra108. doi: 10.1126/scitranslmed.aab1996

PMCID:: PMC7298700

Abstract Article PDF–1.0M

Select item 700227616.

Mechanotransduction dependent control of stereocilia dimensions and row identity in inner hair cells

Jocelyn F. Krey, Paroma Chatterjee, Rachel A. Dumont, Mary O’Sullivan, Dongseok Choi, Jonathan E. Bird, Peter G. Barr-Gillespie

Curr Biol. Author manuscript; available in PMC 2021 Feb 3.

Published in final edited form as: Curr Biol. 2020 Feb 3; 30(3): 442–454.e7. Published online 2020 Jan 2. doi: 10.1016/j.cub.2019.11.076

PMCID:: PMC7002276

Abstract Article PDF–4.1M

Select item 691090817.

The contribution of TMC1 to adaptation of mechanoelectrical transduction channels in cochlear outer hair cells

Adam C. Goldring, Maryline Beurg, Robert Fettiplace

J Physiol. 2019 Dec 15; 597(24): 5949–5961. Published online 2019 Nov 12. doi: 10.1113/JP278799

PMCID:: PMC6910908

Abstract Article PDF–1.8M

Select item 685363818.

TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice

Shuang Liu, Shufeng Wang, Linzhi Zou, Jie Li, Chenmeng Song, Jiaofeng Chen, Qun Hu, Lian Liu, Pingbo Huang, Wei Xiong

eLife. 2019; 8: e47441. Published online 2019 Oct 29. doi: 10.7554/eLife.47441

PMCID:: PMC6853638

Abstract Article PDF–2.8M

Select item 678996719.

A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells

Maryline Beurg, Amanda Barlow, David N. Furness, Robert Fettiplace

Proc Natl Acad Sci U S A. 2019 Oct 8; 116(41): 20743–20749. Published online 2019 Sep 23. doi: 10.1073/pnas.1908058116

PMCID:: PMC6789967

Abstract Article PDF–1.6M

Select item 640845020.

LMO7 deficiency reveals the significance of the cuticular plate for hearing function

Ting-Ting Du, James B. Dewey, Elizabeth L. Wagner, Runjia Cui, Jinho Heo, Jeong-Jin Park, Shimon P. Francis, Edward Perez-Reyes, Stacey J. Guillot, Nicholas E. Sherman, Wenhao Xu, John S Oghalai, Bechara Kachar, Jung-Bum Shin

Nat Commun. 2019; 10: 1117. Published online 2019 Mar 8. doi: 10.1038/s41467-019-09074-4

PMCID:: PMC6408450

Abstract Article PDF–8.4M

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