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Select item 109807931.

Segregation of morphogenetic regulatory function of Shox2 from its cell fate guardian role in sinoatrial node development

Hua Li, Qinghuang Tang, Tianfang Yang, Zhengsen Wang, Dainan Li, Linyan Wang, Liwen Li, Yaoyi Chen, Hai Huang, Yanding Zhang, YiPing Chen

Commun Biol. 2024; 7: 385. Published online 2024 Mar 29. doi: 10.1038/s42003-024-06039-2

PMCID:: PMC10980793

Abstract Article PDF–7.7M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108911543.

Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress

Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini

Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1

PMCID:: PMC10891154

Abstract Article PDF–2.6M

Select item 108766484.

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek

Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8

PMCID:: PMC10876648

Abstract Article PDF–10M

Select item 106846175.

Dbh⁺ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart

Tianyi Sun, Alexander Grassam-Rowe, Zhaoli Pu, Yangpeng Li, Huiying Ren, Yanru An, Xinyu Guo, Wei Hu, Ying Liu, Yuqing Zheng, Zhu Liu, Kun Kou, Xianhong Ou, Tangting Chen, Xuehui Fan, Yangyang Liu, Shu Tu, Yu He, Yue Ren, Ao Chen, Zhouchun Shang, Zhidao Xia, Lucile Miquerol, Nicola Smart, Henggui Zhang, Xiaoqiu Tan, Weinian Shou, Ming Lei

Nat Commun. 2023; 14: 7801. Published online 2023 Nov 28. doi: 10.1038/s41467-023-42658-9

PMCID:: PMC10684617

Abstract Article PDF–23M

Select item 102841406.

Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1

Wei Shi, Angel P. Scialdone, James I. Emerson, Liu Mei, Lauren K. Wasson, Haley A. Davies, Christine E. Seidman, Jonathan G. Seidman, Jeanette G. Cook, Frank L. Conlon

Circ Res. 2023 Jun 23; 133(1): 48–67. Published online 2023 May 31. doi: 10.1161/CIRCRESAHA.122.322223

PMCID:: PMC10284140

Abstract Article PDF–26M

Select item 101226577.

GATA6 coordinates cross-talk between BMP10 and oxidative stress axis in pulmonary arterial hypertension

Tetsuo Toyama, Tatiana V. Kudryashova, Asako Ichihara, Stefania Lenna, Agnieszka Looney, Yuanjun Shen, Lifeng Jiang, Leyla Teos, Theodore Avolio, Derek Lin, Ulas Kaplan, Grace Marden, Vrinda Dambal, Dmitry Goncharov, Horace Delisser, Robert Lafyatis, Francesca Seta, Elena A. Goncharova, Maria Trojanowska

Sci Rep. 2023; 13: 6593. Published online 2023 Apr 22. doi: 10.1038/s41598-023-33779-8

PMCID:: PMC10122657

Abstract Article PDF–4.1M

Select item 100978158.

Warning regarding hematological toxicity of tamoxifen activated CreERT2 in young Rosa26CreERT2 mice

Martina Rossi, Aude Salomon, Nicolas Chaumontel, Jenny Molet, Sabine Bailly, Emmanuelle Tillet, Claire Bouvard

Sci Rep. 2023; 13: 5976. Published online 2023 Apr 12. doi: 10.1038/s41598-023-32633-1

PMCID:: PMC10097815

Abstract Article PDF–6.8M

Select item 99087409.

BMP10 functions independently from BMP9 for the development of a proper arteriovenous network

Hyunwoo Choi, Bo-Gyeong Kim, Yong Hwan Kim, Se-Jin Lee, Young Jae Lee, S. Paul Oh

Angiogenesis. 2023; 26(1): 167–186. Published online 2022 Nov 8. doi: 10.1007/s10456-022-09859-0

PMCID:: PMC9908740

Abstract Article PDF–6.8M

Select item 979482410.

Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages

Wei Feng, Abha Bais, Haoting He, Cassandra Rios, Shan Jiang, Juan Xu, Cindy Chang, Dennis Kostka, Guang Li

Nat Commun. 2022; 13: 7960. Published online 2022 Dec 27. doi: 10.1038/s41467-022-35691-7

PMCID:: PMC9794824

Abstract Article PDF–17M

Select item 953153511.

NOTCH maintains developmental cardiac gene network through WNT5A

Yidong Wang, Pengfei Lu, Bingruo Wu, Bernice E. Morrow, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2022 Oct 4.

Published in final edited form as: J Mol Cell Cardiol. 2018 Dec; 125: 98–105. Published online 2018 Oct 19. doi: 10.1016/j.yjmcc.2018.10.014

PMCID:: PMC9531535

Abstract Article PDF–1.3M

Select item 921519912.

Different cardiovascular and pulmonary phenotypes for single- and double-knock-out mice deficient in BMP9 and BMP10

Claire Bouvard, Ly Tu, Martina Rossi, Agnès Desroches-Castan, Nihel Berrebeh, Elise Helfer, Caroline Roelants, Hequn Liu, Marie Ouarné, Nicolas Chaumontel, Christine Mallet, Christophe Battail, Andreas Bikfalvi, Marc Humbert, Laurent Savale, Thomas Daubon, Pascale Perret, Emmanuelle Tillet, Christophe Guignabert, Sabine Bailly

Cardiovasc Res. 2022 May; 118(7): 1805–1820. Published online 2021 Jun 4. doi: 10.1093/cvr/cvab187

PMCID:: PMC9215199

Abstract Article PDF–2.5M

Select item 917081813.

Maternal nicotine exposure induces congenital heart defects in the offspring of mice

Elizabeth R. Greco, Anish Engineer, Tana Saiyin, Xiangru Lu, MengQi Zhang, Douglas L. Jones, Qingping Feng

J Cell Mol Med. 2022 Jun; 26(11): 3223–3234. Published online 2022 May 6. doi: 10.1111/jcmm.17328

PMCID:: PMC9170818

Abstract Article PDF–4.0M

Select item 875164014.

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López-Tello, Brian Y.H. Lam, Samira N. Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, Cristina M. Branco, Amanda N. Sferruzzi-Perri, Miguel Constância

Dev Cell. 2022 Jan 10; 57(1): 63–79.e8. doi: 10.1016/j.devcel.2021.12.005

PMCID:: PMC8751640

Abstract Article

Select item 868921415.

The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms

Xinyi Huang, Ke Zhao, Mingyang Jiang, Dehui Qiu, Jun Zhou, Zhongzhou Yang

J Biol Chem. 2022 Jan; 298(1): 101449. Published online 2021 Nov 25. doi: 10.1016/j.jbc.2021.101449

PMCID:: PMC8689214

Abstract Article PDF–5.4M

Select item 858931016.

Adhesion G protein–coupled receptor Gpr126/Adgrg6 is essential for placental development

Rebeca Torregrosa-Carrión, Rebeca Piñeiro-Sabarís, Marcos Siguero-Álvarez, Joaquím Grego-Bessa, Luis Luna-Zurita, Vitor Samuel Fernandes, Donal MacGrogan, Didier Y. R. Stainier, José Luis de la Pompa

Sci Adv. 2021 Nov; 7(46): eabj5445. Published online 2021 Nov 12. doi: 10.1126/sciadv.abj5445

PMCID:: PMC8589310

Abstract Article PDF–19M

Select item 806361617.

Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts

Fengling Chen, Jiewen Chen, Hong Wang, Huayuan Tang, Lei Huang, Shijia Wang, Xinru Wang, Xi Fang, Jie Liu, Li Li, Kunfu Ouyang, Zhen Han

Front Cell Dev Biol. 2021; 9: 651655. Published online 2021 Apr 9. doi: 10.3389/fcell.2021.651655

PMCID:: PMC8063616

Abstract Article PDF–4.0M

Select item 800166618.

Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects

Carmen Leung, Anish Engineer, Mella Y. Kim, Xiangru Lu, Qingping Feng

J Cardiovasc Dev Dis. 2021 Mar; 8(3): 29. Published online 2021 Mar 15. doi: 10.3390/jcdd8030029

PMCID:: PMC8001666

Abstract Article PDF–12M

Select item 742270019.

Mesenchyme-specific deletion of Tgf-β1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia

Niki Noe, Ashley Shim, Katelyn Millette, Yongfeng Luo, Mohamad Azhar, Wei Shi, David Warburton, Gianluca Turcatel

Lab Invest. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Lab Invest. 2019 Sep; 99(9): 1363–1375. Published online 2019 Apr 25. doi: 10.1038/s41374-019-0256-3

PMCID:: PMC7422700

Abstract Article PDF–3.3M

Select item 727489520.

A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation

Tomoya Sakamoto, Timothy R. Matsuura, Shibiao Wan, David M. Ryba, Junil Kim, Kyoung Jae Won, Ling Lai, Christopher Petucci, Nataliya Petrenko, Kiran Musunuru, Rick B. Vega, Daniel P. Kelly

Circ Res. Author manuscript; available in PMC 2021 Jun 5.

Published in final edited form as: Circ Res. 2020 Jun 5; 126(12): 1685–1702. Published online 2020 Mar 26. doi: 10.1161/CIRCRESAHA.119.316100

PMCID:: PMC7274895

Abstract Article PDF–2.7M

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