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Items: 1 to 20 of 60

1.
BAG3 promotes proliferation and migration of arterial smooth muscle cells by regulating STAT3 phosphorylation in diabetic vascular remodeling
Xinyue Huang, Jiayan Guo, Anqi Ning, Naijin Zhang, Yingxian Sun
Cardiovasc Diabetol. 2024; 23: 140. Published online 2024 Apr 25. doi: 10.1186/s12933-024-02216-z
PMCID:
PMC11046803
AbstractArticlePDF–23M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
Patrick W. Sheehan, Collin J. Nadarajah, Michael F. Kanan, Jessica N. Patterson, Brenna Novotny, Jennifer H. Lawrence, Melvin W. King, Logan Brase, Casey E. Inman, Carla M. Yuede, Jiyeon Lee, Tirth K. Patel, Oscar Harari, Bruno A. Benitez, Albert A. Davis, Erik S. Musiek
Neuron. Author manuscript; available in PMC 2024 Aug 2.
Published in final edited form as: Neuron. 2023 Aug 2; 111(15): 2383–2398.e7. Published online 2023 Jun 13. doi: 10.1016/j.neuron.2023.05.006
PMCID:
PMC10524543
AbstractArticlePDF–4.2M
4.
Pancreatic beta-cell specific BAG3 knockout results in chronic hyperinsulinemia inducing insulin resistance
Verena Damiani, Alessia Lamolinara, Ilaria Cicalini, Maria Concetta Cufaro, Francesco Del Pizzo, Federica Di Marco, Piero Del Boccio, Beatrice Dufrusine, Michael Hahne, Rossano Lattanzio, Damiana Pieragostino, Manuela Iezzi, Massimo Federici, Maria Caterina Turco, Arianna Maiorana, Carlo Dionisi-Vici, Vincenzo De Laurenzi
Mol Metab. 2023 Aug; 74: 101752. Published online 2023 Jun 10. doi: 10.1016/j.molmet.2023.101752
PMCID:
PMC10333681
AbstractArticlePDF–4.9M
5.
Hematopoietic Stem Cells Preferentially Traffic Misfolded Proteins to Aggresomes and Depend on Aggrephagy to Maintain Protein Homeostasis
Bernadette A. Chua, Connor J. Lennan, Mary Jean Sunshine, Daniela Dreifke, Ashu Chawla, Eric J. Bennett, Robert A.J. Signer
Cell Stem Cell. Author manuscript; available in PMC 2024 Apr 6.
Published in final edited form as: Cell Stem Cell. 2023 Apr 6; 30(4): 460–472.e6. Published online 2023 Mar 21. doi: 10.1016/j.stem.2023.02.010
PMCID:
PMC10164413
AbstractArticlePDF–2.1M
6.
Commentary: BAG3 as a mediator of endosome function and tau clearance
Heng Lin, Carol A. Deaton, Gail V. W. Johnson
Neuroscience. Author manuscript; available in PMC 2024 May 10.
Published in final edited form as: Neuroscience. 2023 May 10; 518: 4–9. Published online 2022 May 10. doi: 10.1016/j.neuroscience.2022.05.002
PMCID:
PMC9646927
AbstractArticlePDF–531K
7.
BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease
Arul M. Mani, Karthik Dhanabalan, Victor Lamin, Thomas Wong, Madhu V. Singh, Ayotunde O. Dokun
Int J Mol Sci. 2022 Sep; 23(18): 10715. Published online 2022 Sep 14. doi: 10.3390/ijms231810715
PMCID:
PMC9502689
AbstractArticlePDF–2.5M
8.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
9.
Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro
Tulsi Patel, Jennifer Hammelman, Siaresh Aziz, Sumin Jang, Michael Closser, Theodore L. Michaels, Jacob A. Blum, David K. Gifford, Hynek Wichterle
Nat Commun. 2022; 13: 5427. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33022-4
PMCID:
PMC9477853
AbstractArticlePDF–7.4M
10.
BAG3 Alleviates Atherosclerosis by Inhibiting Endothelial-to-Mesenchymal Transition via Autophagy Activation
Hongtao Diao, Kaili Wu, Dingming Lan, Dongwei Wang, Jingjing Zhao, Bingying Huang, Xiaoqi Shao, Ruonan Wang, Huiling Tan, Xinyuan Tang, Meiling Yan, Yue Zhang
Genes (Basel) 2022 Aug; 13(8): 1338. Published online 2022 Jul 26. doi: 10.3390/genes13081338
PMCID:
PMC9332509
AbstractArticlePDF–7.6M
11.
BAG3 regulation of Rab35 mediates the Endosomal Sorting Complexes Required for Transport /endolysosome pathway and tau clearance
Heng Lin, Maoping Tang, Changyi Ji, Peter Girardi, Gregor Cvetojevic, Daniel Chen, Shon A. Koren, Gail V. W. Johnson
Biol Psychiatry. Author manuscript; available in PMC 2023 Jul 1.
Published in final edited form as: Biol Psychiatry. 2022 Jul 1; 92(1): 10–24. Published online 2021 Nov 10. doi: 10.1016/j.biopsych.2021.10.024
PMCID:
PMC9085972
AbstractArticlePDF–4.3M
12.
An unexpected role for BAG3 in regulating PARP1 ubiquitination in oxidative stress-related endothelial damage
Naijin Zhang, Ying Zhang, Wei Miao, Chuning Shi, Zihan Chen, Boquan Wu, Yuanming Zou, Qiushi Ma, Shilong You, Saien Lu, Xinyue Huang, Jingwei Liu, Jiaqi Xu, Liu Cao, Yingxian Sun
Redox Biol. 2022 Apr; 50: 102238. Published online 2022 Jan 17. doi: 10.1016/j.redox.2022.102238
PMCID:
PMC8783151
AbstractArticlePDF–9.4M
13.
Strain-induced mechanoresponse depends on cell contractility and BAG3-mediated autophagy
Lukas Lövenich, Georg Dreissen, Christina Hoffmann, Jens Konrad, Ronald Springer, Jörg Höhfeld, Rudolf Merkel, Bernd Hoffmann
Mol Biol Cell. 2021 Oct 1; 32(20): ar9. doi: 10.1091/mbc.E21-05-0254
PMCID:
PMC8684750
AbstractArticlePDF–7.6M
14.
Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy
Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein, Satoru Takahashi, Guang Li, Wilhelm Röll, Wilhelm Bloch, Peter F. M. van der Ven, Wolfgang A. Linke, Sean M. Wu, Pitter F. Huesgen, Jörg Höhfeld, Dieter O. Fürst, Bernd K. Fleischmann, Michael Hesse
Nat Commun. 2021; 12: 3575. Published online 2021 Jun 11. doi: 10.1038/s41467-021-23858-7
PMCID:
PMC8196106
AbstractArticlePDF–8.4M
15.
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover
Thomas G. Martin, Valerie D. Myers, Praveen Dubey, Shubham Dubey, Edith Perez, Christine S. Moravec, Monte S. Willis, Arthur M. Feldman, Jonathan A. Kirk
Nat Commun. 2021; 12: 2942. Published online 2021 May 19. doi: 10.1038/s41467-021-23272-z
PMCID:
PMC8134551
AbstractArticlePDF–7.1M
16.
Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation
Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi
Commun Biol. 2021; 4: 355. Published online 2021 Mar 19. doi: 10.1038/s42003-021-01864-1
PMCID:
PMC7979776
AbstractArticlePDF–5.3M
17.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
18.
An Adult Mouse Model of Dilated Cardiomyopathy Caused by Inducible Cardiac-Specific Bis Deletion
Hye Hyeon Yun, Soon Young Jung, Bong Woo Park, Ji Seung Ko, Kyunghyun Yoo, Jiyoung Yeo, Hong Lim Kim, Hun Jun Park, Ho Joong Youn, Jeong Hwa Lee
Int J Mol Sci. 2021 Feb; 22(3): 1343. Published online 2021 Jan 29. doi: 10.3390/ijms22031343
PMCID:
PMC7866246
AbstractArticlePDF–2.2M
19.
Novel BAG3 Variants in African American Patients with Cardiomyopathy: Reduced β-Adrenergic Responsiveness in Excitation-Contraction.
Arthur M. Feldman, Jennifer Gordon, JuFang Wang, Jianliang Song, Xue-Qian Zhang, Valerie D. Myers, Dhanendra Tomar, Glenn S. Gerhard, Kamel Khalili, Joseph Y. Cheung
J Card Fail. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: J Card Fail. 2020 Dec; 26(12): 1075–1085. Published online 2020 Sep 18. doi: 10.1016/j.cardfail.2020.09.009
PMCID:
PMC7736114
AbstractArticlePDF–1.3M
20.
SRSF3 Is a Critical Requirement for Inclusion of Exon 3 of BIS Pre-mRNA
Ji-Ye Baek, Hye-Hyeon Yun, Soon-Young Jung, Jeehan Lee, Kyunghyun Yoo, Jeong-Hwa Lee
Cells. 2020 Oct; 9(10): 2325. Published online 2020 Oct 19. doi: 10.3390/cells9102325
PMCID:
PMC7589869
AbstractArticlePDF–3.4M

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