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Items: 1 to 20 of 37

1.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
2.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
3.
FANCF hypomethylation is associated with colorectal cancer in Han Chinese
Hang Yu, Ranran Pan, Tong Gao, Dongping Wu, Jieer Ying, Shiwei Duan
Turk J Gastroenterol. 2020 Aug; 31(8): 558–565. doi: 10.5152/tjg.2020.19394
PMCID:
PMC7498186
AbstractArticlePDF–623K
4.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
5.
Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
David Pladevall-Morera, Stephanie Munk, Andreas Ingham, Lorenza Garribba, Eliene Albers, Ying Liu, Jesper V Olsen, Andres J Lopez-Contreras
Nucleic Acids Res. 2019 Sep 5; 47(15): 8004–8018. Published online 2019 Jun 10. doi: 10.1093/nar/gkz510
Correction in:
Nucleic Acids Res. 2019 Sep 5; 47(15): 8332.
PMCID:
PMC6735892
AbstractArticlePDF–5.4M
6.
A novel frame-shift deletion in FANCF gene causing autosomal recessive Fanconi anemia: a case report
Soheila Zareifar, Hassan Dastsooz, Mahdi Shahriari, Mohammad Ali Faghihi, Golsa Shekarkhar, Mohammadreza Bordbar, Omid Reza Zekavat, Nader Shakibazad
BMC Med Genet. 2019; 20: 122. Published online 2019 Jul 9. doi: 10.1186/s12881-019-0855-2
PMCID:
PMC6617641
AbstractArticlePDF–2.6M
7.
HSP90 shapes the consequences of human genetic variation
Georgios I. Karras, Song Yi, Nidhi Sahni, Máté Fischer, Jenny Xie, Marc Vidal, Alan D. D'Andrea, Luke Whitesell, Susan Lindquist
Cell. Author manuscript; available in PMC 2018 Feb 23.
Published in final edited form as: Cell. 2017 Feb 23; 168(5): 856–866.e12. Published online 2017 Feb 16. doi: 10.1016/j.cell.2017.01.023
PMCID:
PMC5325763
AbstractArticlePDF–2.4M
8.
HES1 is a novel interactor of the Fanconi anemia core complex
Cédric S. Tremblay, Feng F. Huang, Ouassila Habi, Caroline C. Huard, Chantal Godin, Georges Lévesque, Madeleine Carreau
Blood. Author manuscript; available in PMC 2016 Dec 13.
Published in final edited form as: Blood. 2008 Sep 1; 112(5): 2062–2070. Published online 2008 Jun 11. doi: 10.1182/blood-2008-04-152710
PMCID:
PMC5154739
AbstractArticlePDF–1.1M
9.
RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cells
Chun-Hua Dai, Jian Li, Ping Chen, He-Guo Jiang, Ming Wu, Yong-Chang Chen
J Biomed Sci. 2015; 22(1): 77. Published online 2015 Sep 18. doi: 10.1186/s12929-015-0185-4
PMCID:
PMC4575453
AbstractArticlePDF–2.0M
10.
Estrogen receptor α, BRCA1, and FANCF promoter methylation occur in distinct subsets of sporadic breast cancers
Minjie Wei, Jinhua Xu, James Dignam, Rita Nanda, Lise Sveen, James Fackenthal, Tatyana A. Grushko, Olufunmilayo I. Olopade
Breast Cancer Res Treat. Author manuscript; available in PMC 2015 Aug 13.
Published in final edited form as: Breast Cancer Res Treat. 2008 Sep; 111(1): 113–120. Published online 2007 Oct 12. doi: 10.1007/s10549-007-9766-6
PMCID:
PMC4535794
AbstractArticlePDF–594K
11.
Modularized Functions of the Fanconi Anemia Core Complex
Yaling Huang, Justin WC Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata, Junjie Chen, Lei Li
Cell Rep. Author manuscript; available in PMC 2015 Jun 26.
Published in final edited form as: Cell Rep. 2014 Jun 26; 7(6): 1849–1857. Published online 2014 Jun 5. doi: 10.1016/j.celrep.2014.04.029
PMCID:
PMC4157997
AbstractArticlePDF–1.4M
12.
The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability
David Fox, 3rd, Zhijiang Yan, Chen Ling, Ye Zhao, Duck-Yeon Lee, Tatsuo Fukagawa, Wei Yang, Weidong Wang
Cell Res. 2014 May; 24(5): 560–575. Published online 2014 Apr 4. doi: 10.1038/cr.2014.42
PMCID:
PMC4011343
AbstractArticlePDF–1.2M
13.
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression
Caroline C. Huard, Cédric S. Tremblay, Audrey Magron, Georges Lévesque, Madeleine Carreau
Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6): 2152–2157. Published online 2014 Jan 27. doi: 10.1073/pnas.1314226111
PMCID:
PMC3926087
AbstractArticlePDF–1.1M
14.
RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation
MIAO HE, HAI-GANG SUN, JUN-YING HAO, YAN-LIN LI, JIAN-KUN YU, YUAN-YUAN YAN, LIN ZHAO, NA LI, YAN WANG, XUE-FENG BAI, ZHAO-JIN YU, ZHI-HONG ZHENG, XIAO-YI MI, EN-HUA WANG, MIN-JIE WEI
Oncol Rep. 2013 May; 29(5): 1721–1729. Published online 2013 Feb 21. doi: 10.3892/or.2013.2295
Correction in:
Oncol Rep. 2022 Jun; 47(6): 116.
PMCID:
PMC3658863
AbstractArticlePDF–921K
15.
A ubiquitin-binding protein FAAP20 links RNF8-mediated ubiquitination to the Fanconi anemia DNA Repair network
Zhijiang Yan, Rong Guo, Manikandan Paramasivam, Weiping Shen, Chen Ling, David Fox, III, Yucai Wang, Anneke B. Oostra, Julia Kuehl, Duck-Yeon Lee, Minoru Takata, Maureen E. Hoatlin, Detlev Schindler, Hans Joenje, Johan P. de Winter, Lei Li, Michael M. Seidman, Weidong Wang
Mol Cell. Author manuscript; available in PMC 2013 Jul 13.
Published in final edited form as: Mol Cell. 2012 Jul 13; 47(1): 61–75. Published online 2012 Jun 14. doi: 10.1016/j.molcel.2012.05.026
PMCID:
PMC3398238
AbstractArticlePDF–4.8M
16.
FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway
Abdullah Mahmood Ali, Arun Pradhan, Thiyam Ramsingh Singh, Changhu Du, Jie Li, Kebola Wahengbam, Elke Grassman, Arleen D. Auerbach, Qishen Pang, Amom Ruhikanta Meetei
Blood. 2012 Apr 5; 119(14): 3285–3294. Prepublished online 2012 Feb 17. doi: 10.1182/blood-2011-10-385963
PMCID:
PMC3321854
AbstractArticle
17.
Image-Based Genome-Wide siRNA Screen Identifies Selective Autophagy Factors
Anthony Orvedahl, Rhea Sumpter, Jr., Guanghua Xiao, Aylwin Ng, Zhongju Zou, Yi Tang, Masahiro Narimatsu, Christopher Gilpin, Qihua Sun, Michael Roth, Christian V. Forst, Jeffrey L. Wrana, Ying E. Zhang, Katherine Luby-Phelps, Ramnik Xavier, Yang Xie, Beth Levine
Nature. Author manuscript; available in PMC 2012 Jun 1.
Published in final edited form as: Nature. 2011 Dec 1; 480(7375): 113–117. doi: 10.1038/nature10546
PMCID:
PMC3229641
AbstractArticlePDF–2.3M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk
Genevieve M. Monsees, Peter Kraft, Stephen J. Chanock, David J. Hunter, Jiali Han
Breast Cancer Res Treat. Author manuscript; available in PMC 2012 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2011 Jan; 125(1): 207–214. Published online 2010 May 23. doi: 10.1007/s10549-010-0947-3
PMCID:
PMC2997162
AbstractArticlePDF–416K
20.
The Fanconi anemia pathway promotes replication-dependent DNA interstrand crosslink repair
Puck Knipscheer, Markus Räschle, Agata Smogorzewska, Milica Enoiu, The Vinh Ho, Orlando D. Schärer, Stephen J. Elledge, Johannes C. Walter
Science. Author manuscript; available in PMC 2010 Jul 26.
Published in final edited form as: Science. 2009 Dec 18; 326(5960): 1698–1701. Published online 2009 Nov 12. doi: 10.1126/science.1182372
PMCID:
PMC2909596
AbstractArticlePDF–1.9M

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