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Select item 93019821.

Effects of Exercise Training on PPARβ/δ Expression in Skeletal Muscle of Rats with Spontaneous Hypertension

MINGXUAN YANG, YANXIA PAN, KUNHUI LI, XIUYUN CHEN, MINYAN LI, JIANPING LIN, MING LI, CHENG LIN

Med Sci Sports Exerc. 2022 Aug; 54(8): 1309–1316. Published online 2022 Apr 2. doi: 10.1249/MSS.0000000000002925

PMCID:: PMC9301982

Abstract Article PDF–1.5M

Select item 85675482.

PPARβ/δ accelerates bone regeneration in diabetic mellitus by enhancing AMPK/mTOR pathway-mediated autophagy

Miao Chen, Dian Jing, Rui Ye, Jianru Yi, Zhihe Zhao

Stem Cell Res Ther. 2021; 12: 566. Published online 2021 Nov 4. doi: 10.1186/s13287-021-02628-8

PMCID:: PMC8567548

Abstract Article PDF–5.7M

Select item 85489383.

Peroxisome proliferator-activated receptor β/δ regulates cerebral vasospasm after subarachnoid hemorrhage via modulating vascular smooth muscle cells phenotypic conversion

Li Xu, Jiang Wu, Yuan Liu, Gang Chen, Chao Ma, Hongrong Zhang

Mol Med Rep. 2021 Dec; 24(6): 860. Published online 2021 Oct 19. doi: 10.3892/mmr.2021.12500

PMCID:: PMC8548938

Abstract Article PDF–2.4M

Select item 82325964.

Cardioprotective Effects of PPARβ/δ Activation against Ischemia/Reperfusion Injury in Rat Heart Are Associated with ALDH2 Upregulation, Amelioration of Oxidative Stress and Preservation of Mitochondrial Energy Production

Ioanna Papatheodorou, Eleftheria Galatou, Georgios-Dimitrios Panagiotidis, Táňa Ravingerová, Antigone Lazou

Int J Mol Sci. 2021 Jun; 22(12): 6399. Published online 2021 Jun 15. doi: 10.3390/ijms22126399

PMCID:: PMC8232596

Abstract Article PDF–2.7M

Select item 70705365.

Pharmacological Blockade of PPAR Isoforms Increases Conditioned Fear Responding in the Presence of Nociceptive Tone

Jessica C. Gaspar, Bright N. Okine, Alvaro Llorente-Berzal, Michelle Roche, David P. Finn

Molecules. 2020 Feb; 25(4): 1007. Published online 2020 Feb 24. doi: 10.3390/molecules25041007

PMCID:: PMC7070536

Abstract Article PDF–2.1M

Select item 55393516.

Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair

Ajit Magadum, Yishu Ding, Lan He, Teayoun Kim, Mohankrishna Dalvoy Vasudevarao, Qinqiang Long, Kevin Yang, Nadeera Wickramasinghe, Harsha V Renikunta, Nicole Dubois, Gilbert Weidinger, Qinglin Yang, Felix B Engel

Cell Res. 2017 Aug; 27(8): 1002–1019. Published online 2017 Jun 16. doi: 10.1038/cr.2017.84

PMCID:: PMC5539351

Abstract Article PDF–9.1M

Select item 48910667.

PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling

Zsuzsanna Ament, James A. West, Elizabeth Stanley, Tom Ashmore, Lee D. Roberts, Jayne Wright, Andrew W. Nicholls, Julian L. Griffin

Free Radic Biol Med. 2016 Jun; 95: 357–368. doi: 10.1016/j.freeradbiomed.2015.11.033

PMCID:: PMC4891066

Abstract Article

Select item 47906438.

MicroRNA-29a induces insulin resistance by targeting PPARδ in skeletal muscle cells

YUEHUA ZHOU, PINGQING GU, WEIJIE SHI, JINGYUN LI, QUN HAO, XIAOMEI CAO, QIN LU, YU ZENG

Int J Mol Med. 2016 Apr; 37(4): 931–938. Published online 2016 Feb 22. doi: 10.3892/ijmm.2016.2499

PMCID:: PMC4790643

Abstract Article PDF–726K

Select item 47492479.

Effects of Peroxisome Proliferator-Activated Receptor-δ Agonist on Cardiac Healing after Myocardial Infarction

Jeong Rang Park, Jong Hwa Ahn, Myeong Hee Jung, Jin-Sin Koh, Yongwhi Park, Seok-Jae Hwang, Young-Hoon Jeong, Choong Hwan Kwak, Young Soo Lee, Han Geuk Seo, Jin Hyun Kim, Jin-Yong Hwang

PLoS One. 2016; 11(2): e0148510. Published online 2016 Feb 10. doi: 10.1371/journal.pone.0148510

PMCID:: PMC4749247

Abstract Article PDF–2.1M

Select item 448664210.

PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells

Victor Samokhvalov, Igor Zlobine, Kristi L. Jamieson, Paul Jurasz, Christopher Chen, Kin Sing Stephen Lee, Bruce D. Hammock, John M. Seubert

Toxicol Lett. Author manuscript; available in PMC 2016 Apr 6.

Published in final edited form as: Toxicol Lett. 2015 Jan 5; 232(1): 10–20. Published online 2014 Oct 6. doi: 10.1016/j.toxlet.2014.09.029

PMCID:: PMC4486642

Abstract Article PDF–1.7M

Select item 415568911.

Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion

Sushant Bhatnagar, Mufaddal S. Soni, Lindsay S. Wrighton, Alexander S. Hebert, Amber S. Zhou, Pradyut K. Paul, Trillian Gregg, Mary E. Rabaglia, Mark P. Keller, Joshua J. Coon, Alan D. Attie

J Biol Chem. 2014 Sep 5; 289(36): 25276–25286. Published online 2014 Jul 7. doi: 10.1074/jbc.M114.575985

PMCID:: PMC4155689

Abstract Article PDF–1.1M

Select item 405520812.

PPARβ activation restores the high glucose-induced impairment of insulin signalling in endothelial cells

A M Quintela, R Jiménez, L Piqueras, M Gómez-Guzmán, J Haro, M J Zarzuelo, A Cogolludo, M J Sanz, M Toral, M Romero, F Pérez-Vizcaíno, J Duarte

Br J Pharmacol. 2014 Jun; 171(12): 3089–3102. Published online 2014 May 27. doi: 10.1111/bph.12646

PMCID:: PMC4055208

Abstract Article PDF–1.5M

Select item 402628513.

Chronic Expression of PPAR-δ by Oligodendrocyte Lineage Cells in the Injured Rat Spinal Cord

Akshata Almad, Dana M. McTigue

J Comp Neurol. Author manuscript; available in PMC 2014 May 19.

Published in final edited form as: J Comp Neurol. 2010 Mar 15; 518(6): 785–799. doi: 10.1002/cne.22242

PMCID:: PMC4026285

Abstract Article PDF–2.7M

Select item 366589114.

Cardiac Peroxisome Proliferator-Activated Receptor δ (PPARδ) as a New Target for Increased Contractility without Altering Heart Rate

Zhih-Cherng Chen, Kung Shing Lee, Li-Jen Chen, Lin-Yu Wang, Ho-Shan Niu, Juei-Tang Cheng

PLoS One. 2013; 8(5): e64229. Published online 2013 May 28. doi: 10.1371/journal.pone.0064229

PMCID:: PMC3665891

Abstract Article PDF–689K

Select item 360528815.

PPARβ/δ Regulates Glucocorticoid- and Sepsis-Induced FOXO1 Activation and Muscle Wasting

Estibaliz Castillero, Nima Alamdari, Zaira Aversa, Aniket Gurav, Per-Olof Hasselgren

PLoS One. 2013; 8(3): e59726. Published online 2013 Mar 21. doi: 10.1371/journal.pone.0059726

PMCID:: PMC3605288

Abstract Article PDF–2.6M

Select item 346973116.

Liver X Receptor β and Peroxisome Proliferator-Activated Receptor δ regulate cholesterol transport in cholangiocytes

Xuefeng Xia, Dongju Jung, Paul Webb, Aijun Zhang, Bin Zhang, Lifei Li, Stephen D. Ayers, Chiara Gabbi, Yoshiyuki Ueno, Jan-Åke Gustafsson, Gianfranco Alpini, David D. Moore, Gene D. LeSage

Hepatology. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Hepatology. 2012 Dec; 56(6): 2288–2296. doi: 10.1002/hep.25919