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Select item 105561061.

The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6

Zachary T. Spencer, Victoria H. Ng, Hassina Benchabane, Ghalia Saad Siddiqui, Deepesh Duwadi, Ben Maines, Jamal M. Bryant, Anna Schwarzkopf, Kai Yuan, Sara N. Kassel, Anant Mishra, Ashley Pimentel, Andres M. Lebensohn, Rajat Rohatgi, Scott A. Gerber, David J. Robbins, Ethan Lee, Yashi Ahmed

Nat Commun. 2023; 14: 6174. Published online 2023 Oct 5. doi: 10.1038/s41467-023-41843-0

PMCID:: PMC10556106

Abstract Article PDF–14M

Select item 105020132.

Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster

Kristina Corthals, Vilma Andersson, Allison Churcher, Johan Reimegård, Anders Enjin

Sci Rep. 2023; 13: 15202. Published online 2023 Sep 14. doi: 10.1038/s41598-023-42506-2

PMCID:: PMC10502013

Abstract Article PDF–5.5M

Select item 94073113.

Dopamine and GPCR-mediated modulation of DN1 clock neurons gates the circadian timing of sleep

Matthias Schlichting, Shlesha Richhariya, Nicholas Herndon, Dingbang Ma, Jason Xin, William Lenh, Katharine Abruzzi, Michael Rosbash

Proc Natl Acad Sci U S A. 2022 Aug 23; 119(34): e2206066119. Published online 2022 Aug 15. doi: 10.1073/pnas.2206066119

PMCID:: PMC9407311

Abstract Article PDF–2.3M

Select item 90620814.

Canonical Wnt Signaling Promotes Formation of Somatic Permeability Barrier for Proper Germ Cell Differentiation

Ting-An Chen, Kun-Yang Lin, Shun-Min Yang, Chen-Yuan Tseng, Yu-Ting Wang, Chi-Hung Lin, Lichao Luo, Yu Cai, Hwei-Jan Hsu

Front Cell Dev Biol. 2022; 10: 877047. Published online 2022 Apr 19. doi: 10.3389/fcell.2022.877047

PMCID:: PMC9062081

Abstract Article PDF–6.1M

Select item 87279865.

Loxl2 is a mediator of cardiac aging in Drosophila melanogaster, genetically examining the role of aging clock genes

Mark J Bouska, Hua Bai

G3 (Bethesda) 2022 Jan; 12(1): jkab381. Published online 2021 Nov 4. doi: 10.1093/g3journal/jkab381

PMCID:: PMC8727986

Abstract Article PDF–988K

Select item 81578296.

G-Protein Coupled Receptors (GPCRs) in Insects—A Potential Target for New Insecticide Development

Nannan Liu, Ting Li, Yifan Wang, Shikai Liu

Molecules. 2021 May; 26(10): 2993. Published online 2021 May 18. doi: 10.3390/molecules26102993

PMCID:: PMC8157829

Abstract Article PDF–2.4M

Select item 80463447.

Extracellular spreading of Wingless is required for Drosophila oogenesis

Xiaoxi Wang, Kimberly S. LaFever, Indrayani Waghmare, Andrea Page-McCaw

PLoS Genet. 2021 Apr; 17(4): e1009469. Published online 2021 Apr 2. doi: 10.1371/journal.pgen.1009469

PMCID:: PMC8046344

Abstract Article PDF–2.5M

Select item 80213988.

Single-cell transcriptomics of the Drosophila wing disc reveals instructive epithelium-to-myoblast interactions

Nicholas J Everetts, Melanie I Worley, Riku Yasutomi, Nir Yosef, Iswar K Hariharan

eLife. 2021; 10: e61276. Published online 2021 Mar 22. doi: 10.7554/eLife.61276

PMCID:: PMC8021398

Abstract Article PDF–5.1M

Select item 76954529.

Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders

David Melamed, Daniel Kalderon

eLife. 2020; 9: e61204. Published online 2020 Nov 2. doi: 10.7554/eLife.61204

PMCID:: PMC7695452

Abstract Article PDF–6.2M

Select item 764147410.

No Evidence that Wnt Ligands Are Required for Planar Cell Polarity in Drosophila

Ben Ewen-Campen, Typhaine Comyn, Eric Vogt, Norbert Perrimon

Cell Rep. Author manuscript; available in PMC 2020 Nov 4.

Published in final edited form as: Cell Rep. 2020 Sep 8; 32(10): 108121. doi: 10.1016/j.celrep.2020.108121

PMCID:: PMC7641474

Abstract Article PDF–876K

Select item 761155911.

Patterning and growth control by membrane-tethered Wingless

Cyrille Alexandre, Alberto Baena-Lopez, Jean-Paul Vincent

Nature. Author manuscript; available in PMC 2021 Aug 23.

Published in final edited form as: Nature. 2014 Jan 9; 505(7482): 180–5. Published online 2013 Dec 25. doi: 10.1038/nature12879

PMCID:: PMC7611559

Abstract Article PDF–4.1M

Select item 755019212.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 750565513.

Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts

Amrutha Kizhedathu, Rose Sebastian Kunnappallil, Archit V Bagul, Puja Verma, Arjun Guha

eLife. 2020; 9: e57056. Published online 2020 Sep 2. doi: 10.7554/eLife.57056

PMCID:: PMC7505655

Abstract Article PDF–2.8M

Select item 737030714.

Dally-like protein sequesters multiple Wnt ligands in the Drosophila germarium

Indrayani Waghmare, Xiaoxi Wang, Andrea Page-McCaw

Dev Biol. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: Dev Biol. 2020 Aug 1; 464(1): 88–102. Published online 2020 May 28. doi: 10.1016/j.ydbio.2020.05.004

PMCID:: PMC7370307

Abstract Article PDF–3.8M

Select item 736588315.

Investigation of Isoform Specific Functions of the V-ATPase a Subunit During Drosophila Wing Development

Dongqing Mo, Yao Chen, Na Jiang, Jie Shen, Junzheng Zhang

Front Genet. 2020; 11: 723. Published online 2020 Jul 10. doi: 10.3389/fgene.2020.00723

PMCID:: PMC7365883

Abstract Article PDF–8.0M

Select item 682603416.

Casein kinase 1α decreases β-catenin levels at adherens junctions to facilitate wound closure in Drosophila larvae

Chang-Ru Tsai, Michael J. Galko

Development. 2019 Oct 15; 146(20): dev175133. Published online 2019 Oct 2. doi: 10.1242/dev.175133

PMCID:: PMC6826034

Abstract Article

Select item 656396117.

Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization

Ai Tian, Deepesh Duwadi, Hassina Benchabane, Yashi Ahmed

PLoS Genet. 2019 Jun; 15(6): e1008111. Published online 2019 Jun 13. doi: 10.1371/journal.pgen.1008111

PMCID:: PMC6563961

Abstract Article PDF–8.4M

Select item 650653918.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 645900219.

RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes

Joel Johansson, Mate Naszai, Michael C. Hodder, Karen A. Pickering, Bryan W. Miller, Rachel A. Ridgway, Yachuan Yu, Pascal Peschard, Saskia Brachmann, Andrew D. Campbell, Julia B. Cordero, Owen J. Sansom

Cell Stem Cell. 2019 Apr 4; 24(4): 592–607.e7. doi: 10.1016/j.stem.2019.02.002