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Select item 114024741.

The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy

Cristiana Dondi, Georg Vogler, Anjali Gupta, Stanley M. Walls, Anaïs Kervadec, James Marchant, Michaela R. Romero, Soda Diop, Jason Goode, John B. Thomas, Alex R. Colas, Rolf Bodmer, Marc Montminy, Karen Ocorr

Cell Rep. Author manuscript; available in PMC 2024 Sep 15.

Published in final edited form as: Cell Rep. 2024 Aug 27; 43(8): 114549. Published online 2024 Aug 1. doi: 10.1016/j.celrep.2024.114549

PMCID:: PMC11402474

Abstract Article PDF–3.6M

Select item 110631602.

Large-language models facilitate discovery of the molecular signatures regulating sleep and activity

Di Peng, Liubin Zheng, Dan Liu, Cheng Han, Xin Wang, Yan Yang, Li Song, Miaoying Zhao, Yanfeng Wei, Jiayi Li, Xiaoxue Ye, Yuxiang Wei, Zihao Feng, Xinhe Huang, Miaomiao Chen, Yujie Gou, Yu Xue, Luoying Zhang

Nat Commun. 2024; 15: 3685. Published online 2024 May 1. doi: 10.1038/s41467-024-48005-w

PMCID:: PMC11063160

Abstract Article PDF–2.7M

Select item 108501613.

Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies

Elena Marchesan, Alice Nardin, Sofia Mauri, Greta Bernardo, Vivek Chander, Simone Di Paola, Monica Chinellato, Sophia von Stockum, Joy Chakraborty, Stephanie Herkenne, Valentina Basso, Emilie Schrepfer, Oriano Marin, Laura Cendron, Diego L. Medina, Luca Scorrano, Elena Ziviani

Cell Death Differ. 2024 Feb; 31(2): 217–238. Published online 2024 Jan 18. doi: 10.1038/s41418-023-01251-9

PMCID:: PMC10850161

Abstract Article PDF–19M

Select item 104573424.

PINK1 and Parkin regulate IP₃R-mediated ER calcium release

Su Jin Ham, Heesuk Yoo, Daihn Woo, Da Hyun Lee, Kyu-Sang Park, Jongkyeong Chung

Nat Commun. 2023; 14: 5202. Published online 2023 Aug 25. doi: 10.1038/s41467-023-40929-z

PMCID:: PMC10457342

Abstract Article PDF–3.1M

Select item 104457345.

Systematic analysis of the Frazzled receptor interactome establishes previously unreported regulators of axon guidance

Yixin Zang, Greg J. Bashaw

Development. 2023 Aug 1; 150(15): dev201636. Published online 2023 Aug 1. doi: 10.1242/dev.201636

PMCID:: PMC10445734

Abstract Article

Select item 101057366.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 98461507.

The calcineurin regulator Sarah enables distinct forms of homeostatic plasticity at the Drosophila neuromuscular junction

Noah S. Armstrong, C. Andrew Frank

Front Synaptic Neurosci. 2022; 14: 1033743. Published online 2023 Jan 4. doi: 10.3389/fnsyn.2022.1033743

PMCID:: PMC9846150

Abstract Article PDF–9.4M

Select item 96769848.

CBP-Mediated Acetylation of Importin α Mediates Calcium-Dependent Nucleocytoplasmic Transport of Selective Proteins in Drosophila Neurons

Jae Ho Cho, Min Gu Jo, Eun Seon Kim, Na Yoon Lee, Soon Ha Kim, Chang Geon Chung, Jeong Hyang Park, Sung Bae Lee

Mol Cells. 2022 Nov 30; 45(11): 855–867. Published online 2022 Sep 28. doi: 10.14348/molcells.2022.0104

PMCID:: PMC9676984

Abstract Article PDF–2.2M

Select item 92738689.

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov

Front Aging Neurosci. 2022; 14: 914017. Published online 2022 Jun 28. doi: 10.3389/fnagi.2022.914017

PMCID:: PMC9273868

Abstract Article PDF–3.6M

Select item 889598910.

Transgenic Drosophila lines for LexA-dependent gene and growth regulation

Kathleen R Chang, Deborah D Tsao, Celine Bennett, Elaine Wang, Jax F Floyd, Ashley S Y Tay, Emily Greenwald, Ella S Kim, Catherine Griffin, Elizabeth Morse, Townley Chisholm, Anne E Rankin, Luis Alberto Baena-Lopez, Nicole Lantz, Elizabeth Fox, Lutz Kockel, Seung K Kim, Sangbin Park

G3 (Bethesda) 2022 Mar; 12(3): jkac018. Published online 2022 Jan 19. doi: 10.1093/g3journal/jkac018

PMCID:: PMC8895989

Abstract Article PDF–1.0M

Select item 879447011.

A phosphoswitch at acinus-serine⁴³⁷ controls autophagic responses to cadmium exposure and neurodegenerative stress

Nilay Nandi, Zuhair Zaidi, Charles Tracy, Helmut Krämer

eLife. 2022; 11: e72169. Published online 2022 Jan 17. doi: 10.7554/eLife.72169

PMCID:: PMC8794470

Abstract Article PDF–5.3M

Select item 866448612.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 849187613.

Minibrain kinase and calcineurin coordinate activity-dependent bulk endocytosis through synaptojanin

Yi-Jheng Peng, Junhua Geng, Ying Wu, Cristian Pinales, Jennifer Langen, Yen-Ching Chang, Christopher Buser, Karen T. Chang

J Cell Biol. 2021 Dec 6; 220(12): e202011028. Published online 2021 Oct 1. doi: 10.1083/jcb.202011028

PMCID:: PMC8491876

Abstract Article PDF–7.6M

Select item 774841514.

Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3

Jeong Hyang Park, Chang Geon Chung, Sung Soon Park, Davin Lee, Kyung Min Kim, Yeonjin Jeong, Eun Seon Kim, Jae Ho Cho, Yu-Mi Jeon, C-K James Shen, Hyung-Jun Kim, Daehee Hwang, Sung Bae Lee

eLife. 2020; 9: e60132. Published online 2020 Dec 11. doi: 10.7554/eLife.60132

PMCID:: PMC7748415

Abstract Article PDF–6.2M

Select item 755019215.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 754644516.

Overlapping activities of ELAV/Hu family RNA binding proteins specify the extended neuronal 3’ UTR landscape in Drosophila

Lu Wei, Seungjae Lee, Sonali Majumdar, Binglong Zhang, Piero Sanfilippo, Brian Joseph, Pedro Miura, Matthias Soller, Eric C. Lai

Mol Cell. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Mol Cell. 2020 Oct 1; 80(1): 140–155.e6. doi: 10.1016/j.molcel.2020.09.007

PMCID:: PMC7546445

Abstract Article PDF–3.8M

Select item 710142817.

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

Patricia Deng, Anzer Khan, Dionna Jacobson, Nagraj Sambrani, Leeanne McGurk, Xianghua Li, Aswathy Jayasree, Jan Hejatko, Galit Shohat-Ophir, Mary A. O’Connell, Jin Billy Li, Liam P. Keegan

Nat Commun. 2020; 11: 1580. Published online 2020 Mar 27. doi: 10.1038/s41467-020-15435-1

PMCID:: PMC7101428

Abstract Article PDF–1.6M

Select item 696157818.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 662341519.

Calcineurin and Its Regulator Sra/DSCR1 Are Essential for Sleep in Drosophila

Yasuhiro Nakai, Junjiro Horiuchi, Manabu Tsuda, Satomi Takeo, Shin Akahori, Takashi Matsuo, Kazuhiko Kume, Toshiro Aigaki

J Neurosci. 2011 Sep 7; 31(36): 12759–12766. doi: 10.1523/JNEUROSCI.1337-11.2011

PMCID:: PMC6623415

Abstract Article PDF–1.8M

Select item 662325220.

Pan-Neuronal Knockdown of Calcineurin Reduces Sleep in the Fruit Fly, Drosophila melanogaster

Jun Tomita, Madoka Mitsuyoshi, Taro Ueno, Yoshinori Aso, Hiromu Tanimoto, Yasuhiro Nakai, Toshiro Aigaki, Shoen Kume, Kazuhiko Kume

J Neurosci. 2011 Sep 14; 31(37): 13137–13146. doi: 10.1523/JNEUROSCI.5860-10.2011

PMCID:: PMC6623252

Abstract Article PDF–3.3M

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