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Select item 111782961.

Clock genes regulate skeletal muscle energy metabolism through NAMPT/NAD⁺/SIRT1 following heavy-load exercise

Yu Xia, Binyu Yao, Zeting Fu, Lunyu Li, Songlin Jin, Bo Qu, Ying Huang, Haili Ding

Am J Physiol Regul Integr Comp Physiol. 2023 Nov 1; 325(5): R490–R503. Published online 2023 Aug 7. doi: 10.1152/ajpregu.00261.2022

PMCID:: PMC11178296

Abstract Article

Select item 111617562.

Phosphorylation of DNA-binding domains of CLOCK–BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells

Yuta Otobe, Eui Min Jeong, Shunsuke Ito, Yuta Shinohara, Nobuhiro Kurabayashi, Atsu Aiba, Yoshitaka Fukada, Jae Kyoung Kim, Hikari Yoshitane

Proc Natl Acad Sci U S A. 2024 Jun 4; 121(23): e2316858121. Published online 2024 May 28. doi: 10.1073/pnas.2316858121

PMCID:: PMC11161756

Abstract Article PDF–4.4M

Select item 108554993.

Mucosal Genes Encoding Clock, Inflammation and Their Mutual Regulators Are Disrupted in Pediatric Patients with Active Ulcerative Colitis

Sapir Labes, Oren Froy, Yuval Tabach, Raanan Shamir, Dror S. Shouval, Yael Weintraub

Int J Mol Sci. 2024 Feb; 25(3): 1488. Published online 2024 Jan 25. doi: 10.3390/ijms25031488

PMCID:: PMC10855499

Abstract Article PDF–1.9M

Select item 107193384.

Sex-dependent relationship of polymorphisms in CLOCK and REV-ERBα genes with body mass index and lipid levels in children

Claudia Vales-Villamarín, Olaya de Dios, Ignacio Mahíllo-Fernández, Macarena Perales, Iris Pérez-Nadador, Teresa Gavela-Pérez, Leandro Soriano-Guillén, Carmen Garcés

Sci Rep. 2023; 13: 22127. Published online 2023 Dec 13. doi: 10.1038/s41598-023-49506-2

PMCID:: PMC10719338

Abstract Article PDF–1.7M

Select item 106652455.

Relationship Between Breast Cancer Risk and Polymorphisms in CLOCK Gene: A Systematic Review and Meta-Analysis

Yi Shi, Lixing Wu, Xuenian Ji, Yunru Li, Zhicheng Zhang

Biochem Genet. 2023; 61(6): 2348–2362. Published online 2023 Apr 10. doi: 10.1007/s10528-023-10372-2

PMCID:: PMC10665245

Abstract Article PDF–1.9M

Select item 105658766.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104237477.

Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma

Lizhi Pang, Madeline Dunterman, Wenjing Xuan, Annette Gonzalez, Yiyun Lin, Wen-Hao Hsu, Fatima Khan, Robert S. Hagan, William A. Muller, Amy B. Heimberger, Peiwen Chen

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112127. Published online 2023 Feb 14. doi: 10.1016/j.celrep.2023.112127

PMCID:: PMC10423747

Abstract Article PDF–2.6M

Select item 102620318.

Novel CLOCK and NR1D2 variants in 64 sighted Japanese individuals with non-24-hour sleep–wake rhythm disorder

Akiko Hida, Aritoshi Iida, Motoki Ukai, Hiroshi Kadotani, Makoto Uchiyama, Takashi Ebisawa, Yuichi Inoue, Shingo Kitamura, Kazuo Mishima

Sleep. 2023 Jun; 46(6): zsad063. Published online 2023 Mar 10. doi: 10.1093/sleep/zsad063

PMCID:: PMC10262031

Article PDF–2.0M

Select item 102394059.

Clock 3111 T/C and Period3 VNTR gene polymorphisms and proteins, and melatonin levels in women with infertility

Recai Aci, Gulay Ciftci, Serbulent Yigit, Ozlem Sezer, Adem Keskin

J Assist Reprod Genet. 2023 May; 40(5): 1109–1116. Published online 2023 Feb 27. doi: 10.1007/s10815-023-02756-5

PMCID:: PMC10239405

Abstract Article PDF–886K

Select item 1022277310.

Association between CLOCK Gene Polymorphisms and Insomnia Risk According to Food Groups: A KoGES Longitudinal Study

Sunghee Lee

Nutrients. 2023 May; 15(10): 2300. Published online 2023 May 13. doi: 10.3390/nu15102300

PMCID:: PMC10222773

Abstract Article PDF–325K

Select item 1015799111.

Association of rotating night shift work, CLOCK, MTNR1A, MTNR1B genes polymorphisms and their interactions with type 2 diabetes among steelworkers: a case–control study

Qinglin Li, Shengkui Zhang, Han Wang, Zhende Wang, Xiaohong Zhang, Yongbin Wang, Juxiang Yuan

BMC Genomics. 2023; 24: 232. Published online 2023 May 3. doi: 10.1186/s12864-023-09328-y

PMCID:: PMC10157991

Abstract Article PDF–1.1M

Select item 992625712.

Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle

Meng Qu, Guoxin Zhang, Han Qu, Alexander Vu, Raymond Wu, Hidekazu Tsukamoto, Zhenyu Jia, Wendong Huang, Heinz-Josef Lenz, Jeremy N. Rich, Steve A. Kay

Proc Natl Acad Sci U S A. 2023 Jan 10; 120(2): e2214829120. Published online 2023 Jan 3. doi: 10.1073/pnas.2214829120

PMCID:: PMC9926257

Abstract Article PDF–730K

Select item 946034913.

Influence of CLOCK Gene Variants on Weight Response after Bariatric Surgery

Macarena Torrego-Ellacuría, Ana Barabash, Pilar Matía-Martín, Andrés Sánchez-Pernaute, Antonio J. Torres, Alfonso L. Calle-Pascual, Miguel A. Rubio-Herrera

Nutrients. 2022 Sep; 14(17): 3472. Published online 2022 Aug 24. doi: 10.3390/nu14173472

PMCID:: PMC9460349

Abstract Article PDF–1.0M

Select item 917779414.

Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma

Wenjing Xuan, Wen-Hao Hsu, Fatima Khan, Madeline Dunterman, Lizhi Pang, Derek A. Wainwright, Atique U. Ahmed, Amy B. Heimberger, Maciej S. Lesniak, Peiwen Chen

Cancer Immunol Res. Author manuscript; available in PMC 2022 Dec 3.

Published in final edited form as: Cancer Immunol Res. 2022 Jun 3; 10(6): 770–784. doi: 10.1158/2326-6066.CIR-21-0559

PMCID:: PMC9177794

Abstract Article PDF–3.4M

Select item 916158015.

Association between CLOCK 3111 T/C polymorphism with ghrelin, GLP-1, food timing, sleep and chronotype in overweight and obese Iranian adults

Sara Rahati, Mostafa Qorbani, Anoosh Naghavi, Milad Heidari Nia, Hamideh Pishva

BMC Endocr Disord. 2022; 22: 147. Published online 2022 Jun 2. doi: 10.1186/s12902-022-01063-x

PMCID:: PMC9161580

Abstract Article PDF–1.0M

Select item 864810916.

NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1

Yang Shen, Mehari Endale, Wei Wang, Andrew R. Morris, Lauren J. Francey, Rachel L. Harold, David W. Hammers, Zhiguang Huo, Carrie L. Partch, John B. Hogenesch, Zhao-Hui Wu, Andrew C. Liu

PLoS Genet. 2021 Nov; 17(11): e1009933. Published online 2021 Nov 22. doi: 10.1371/journal.pgen.1009933

PMCID:: PMC8648109

Abstract Article PDF–2.6M

Select item 851166017.

Low CLOCK and CRY2 in 2nd trimester human maternal blood and risk of preterm birth: a nested case-control study^†

Guoli Zhou, Thu V Duong, Eric P Kasten, Hanne M Hoffmann

Biol Reprod. 2021 Oct; 105(4): 827–836. Published online 2021 Jun 18. doi: 10.1093/biolre/ioab119

PMCID:: PMC8511660

Abstract Article PDF–581K

Select item 830864418.

Daily Rhythm of Fractal Cardiac Dynamics Links to Weight Loss Resistance: Interaction with CLOCK 3111T/C Genetic Variant

Hui-Wen Yang, Marta Garaulet, Peng Li, Cristina Bandin, Chen Lin, Men-Tzung Lo, Kun Hu

Nutrients. 2021 Jul; 13(7): 2463. Published online 2021 Jul 19. doi: 10.3390/nu13072463

PMCID:: PMC8308644

Abstract Article PDF–12M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 806709720.

Assessment of Selected Clock Proteins (CLOCK and CRY1) and Their Relationship with Biochemical, Anthropometric, and Lifestyle Parameters in Hypertensive Patients

Aniceta Ada Mikulska, Teresa Grzelak, Marta Pelczyńska, Paweł Bogdański, Krystyna Czyżewska

Biomolecules. 2021 Apr; 11(4): 517. Published online 2021 Mar 30. doi: 10.3390/biom11040517

PMCID:: PMC8067097

Abstract Article PDF–569K

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