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Select item 111235271.

Expression of FAP in Oral Leukoplakia and Oral Squamous Cell Carcinoma

Ran Li, Rongrong Zhang, Xiaotong Shi, Xiaofeng Jiao, Yanwei Li, Yingjiao Zhao, Tiantian Liu, Chunye Zhang

Int Dent J. 2024 Jun; 74(3): 581–588. Published online 2024 Jan 26. doi: 10.1016/j.identj.2023.12.011

PMCID:: PMC11123527

Abstract Article PDF–1.1M

Select item 110288712.

Anti-tumor effects of DNA vaccine targeting human fibroblast activation protein α by producing specific immune responses and altering tumor microenvironment in the 4T1 murine breast cancer model

Qiu Xia, Fang-Fang Zhang, Fei Geng, Chen-Lu Liu, Ping Xu, Zhen-Zhen Lu, Bin Yu, Hui Wu, Jia-Xin Wu, Hai-Hong Zhang, Wei Kong, Xiang-Hui Yu

Cancer Immunol Immunother. 2016 May; 65(5): 613–624. Published online 2016 Mar 28. doi: 10.1007/s00262-016-1827-4

PMCID:: PMC11028871

Abstract Article PDF–2.0M

Select item 107720423.

FSHD muscle shows perturbation in fibroadipogenic progenitor cells, mitochondrial function and alternative splicing independently of inflammation

Elise N Engquist, Anna Greco, Leo A B Joosten, Baziel G M van Engelen, Peter S Zammit, Christopher R S Banerji

Hum Mol Genet. 2024 Jan 15; 33(2): 182–197. Published online 2023 Oct 19. doi: 10.1093/hmg/ddad175

PMCID:: PMC10772042

Abstract Article PDF–2.2M

Select item 107435254.

FAP expression in adipose tissue macrophages promotes obesity and metabolic inflammation

Yunyun Wu, Chao Wu, Tiancong Shi, Qian Cai, Tianyao Wang, Yingluo Xiong, Yubin Zhang, Wei Jiang, Mingfang Lu, Zhengrong Chen, Jing Chen, Jiqiu Wang, Rui He

Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51): e2303075120. Published online 2023 Dec 15. doi: 10.1073/pnas.2303075120

PMCID:: PMC10743525

Abstract Article PDF–7.0M

Select item 104984365.

FAP is critical for ovarian cancer cell survival by sustaining NF-κB activation through recruitment of PRKDC in lipid rafts

Bin Li, Zuo Ding, Ozlem Calbay, Yue Li, Tao Li, Lingtao Jin, Shuang Huang

Cancer Gene Ther. Author manuscript; available in PMC 2023 Sep 13.

Published in final edited form as: Cancer Gene Ther. 2023 Apr; 30(4): 608–621. Published online 2022 Dec 9. doi: 10.1038/s41417-022-00575-x

PMCID:: PMC10498436

Abstract Article PDF–3.1M

Select item 104492736.

Comprehensive analysis of the oncogenic and immunological role of FAP and identification of the ceRNA network in human cancers

Weiqian Mai, Qingyou Liu, Jiasheng Li, Mincheng Zheng, Fuman Yan, Hui Liu, Yuhe Lei, Jinwen Xu, Jiean Xu

Aging (Albany NY) 2023 May 15; 15(9): 3738–3758. Published online 2023 May 9. doi: 10.18632/aging.204707

PMCID:: PMC10449273

Abstract Article PDF–4.4M

Select item 104281907.

Fibroblast activation protein (FAP)-targeted radionuclide therapy: which ligand is the best?

Rubel Chakravarty, Wenyu Song, Sudipta Chakraborty, Weibo Cai

Eur J Nucl Med Mol Imaging. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Eur J Nucl Med Mol Imaging. 2023 Aug; 50(10): 2935–2939. doi: 10.1007/s00259-023-06338-6

PMCID:: PMC10428190

Article PDF–490K

Select item 104155438.

Identifying the oncogenic roles of FAP in human cancers based on systematic analysis

Chao Ma, Shuaishuai Xi, He Sun, Meng Zhang, Yuanmin Pei

Aging (Albany NY) 2023 Jul 31; 15(14): 7056–7083. Published online 2023 Jul 24. doi: 10.18632/aging.204892

PMCID:: PMC10415543

Abstract Article PDF–6.5M

Select item 103511899.

TGF-β1 dominates stromal fibroblast-mediated EMT via the FAP/VCAN axis in bladder cancer cells

Qinrong Ping, Chunhui Wang, Xin Cheng, Yiming Zhong, Ruping Yan, Meng Yang, Yunqiang Shi, Xiangmeng Li, Xiao Li, Wenwen Huang, Liqiong Wang, Xiaofang Bi, Libing Hu, Yang Yang, Yingbao Wang, Rui Gong, Jun Tan, Rui Li, Hui Li, Jian Li, Wenju Wang, Ruhong Li

J Transl Med. 2023; 21: 475. Published online 2023 Jul 17. doi: 10.1186/s12967-023-04303-3

PMCID:: PMC10351189

Abstract Article PDF–12M

Select item 1009163110.

FAP-targeted CAR-T suppresses MDSCs recruitment to improve the antitumor efficacy of claudin18.2-targeted CAR-T against pancreatic cancer

Yifan Liu, Yansha Sun, Peng Wang, Songling Li, Yiwei Dong, Min Zhou, Bizhi Shi, Hua Jiang, Ruixin Sun, Zonghai Li

J Transl Med. 2023; 21: 255. Published online 2023 Apr 12. doi: 10.1186/s12967-023-04080-z

PMCID:: PMC10091631

Abstract Article PDF–10M

Select item 998091711.

Stromal FAP Expression is Associated with MRI Visibility and Patient Survival in Prostate Cancer

Teijo Pellinen, Kevin Sandeman, Sami Blom, Riku Turkki, Annabrita Hemmes, Katja Välimäki, Juho Eineluoto, Anu Kenttämies, Stig Nordling, Olli Kallioniemi, Antti Rannikko, Tuomas Mirtti

Cancer Res Commun. 2022 Mar; 2(3): 172–181. Published online 2022 Mar 21. doi: 10.1158/2767-9764.CRC-21-0183

PMCID:: PMC9980917

Abstract Article PDF–6.0M

Select item 989331412.

Comprehensive Analysis of Fibroblast Activation Protein Expression in Interstitial Lung Diseases

Penghui Yang, Qun Luo, Xinlu Wang, Qi Fang, Zhenli Fu, Jia Li, Yunxin Lai, Xiaobo Chen, Xin Xu, Xiaomin Peng, Kongzhen Hu, Xiaowei Nie, Shaoyu Liu, Jinhe Zhang, Junqi Li, Chenyou Shen, Yingying Gu, Jianping Liu, Jingyu Chen, Nanshan Zhong, Jin Su

Am J Respir Crit Care Med. 2023 Jan 15; 207(2): 160–172. Published online 2022 Aug 19. doi: 10.1164/rccm.202110-2414OC

PMCID:: PMC9893314

Abstract Article PDF–2.1M

Select item 923162313.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 885375914.

Serum Exosomal lncRNA AC007099.1 Regulates the Expression of Neuropeptide-Related FAP, as a Potential Biomarker for Hepatocarcinogenesis

Luqian Li, Fei Xiao, Guolian Liu, Yufeng Chen

Dis Markers. 2022; 2022: 9501008. Published online 2022 Feb 10. doi: 10.1155/2022/9501008

PMCID:: PMC8853759

Abstract Article PDF–1.9M

Select item 877497315.

Expression of Fibroblast Activation Protein Is Enriched in Neuroendocrine Prostate Cancer and Predicts Worse Survival

Panagiotis J. Vlachostergios, Athanasios Karathanasis, Vassilios Tzortzis

Genes (Basel) 2022 Jan; 13(1): 135. Published online 2022 Jan 13. doi: 10.3390/genes13010135

PMCID:: PMC8774973

Abstract Article PDF–2.0M

Select item 874895816.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 874644117.

Design, Synthesis and Preclinical Assessment of ^99mTc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging

Diana Trujillo-Benítez, Myrna Luna-Gutiérrez, Guillermina Ferro-Flores, Blanca Ocampo-García, Clara Santos-Cuevas, Gerardo Bravo-Villegas, Enrique Morales-Ávila, Pedro Cruz-Nova, Lorenza Díaz-Nieto, Janice García-Quiroz, Erika Azorín-Vega, Antonio Rosato, Laura Meléndez-Alafort

Molecules. 2022 Jan; 27(1): 264. Published online 2022 Jan 1. doi: 10.3390/molecules27010264

PMCID:: PMC8746441

Abstract Article PDF–3.9M

Select item 831507818.

Molecular imaging of fibroblast activation protein after myocardial infarction using the novel radiotracer [⁶⁸Ga]MHLL1

Laura B.N. Langer, Annika Hess, Zekiye Korkmaz, Jochen Tillmanns, Laura M. Reffert, Jens P. Bankstahl, Frank M. Bengel, James T. Thackeray, Tobias L. Ross

Theranostics. 2021; 11(16): 7755–7766. Published online 2021 Jun 22. doi: 10.7150/thno.51419

PMCID:: PMC8315078

Abstract Article PDF–1.5M

Select item 822644919.

In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA⁵.SA.FAPi and DOTA.SA.FAPi

Euy Sung Moon, Yentl Van Rymenant, Sandeep Battan, Joni De Loose, An Bracke, Pieter Van der Veken, Ingrid De Meester, Frank Rösch

Molecules. 2021 Jun; 26(12): 3482. Published online 2021 Jun 8. doi: 10.3390/molecules26123482

PMCID:: PMC8226449

Abstract Article PDF–1.9M

Select item 814963320.

Colorectal cancer cell intrinsic fibroblast activation protein alpha binds to Enolase1 and activates NF-κB pathway to promote metastasis

Ziming Yuan, Hanqing Hu, Yihao Zhu, Weiyuan Zhang, Qingxiao Fang, Tianyu Qiao, Tianyi Ma, Meng Wang, Rui Huang, Qingchao Tang, Feng Gao, Chaoxia Zou, Xu Gao, Guiyu Wang, Xishan Wang

Cell Death Dis. 2021 Jun; 12(6): 543. Published online 2021 May 25. doi: 10.1038/s41419-021-03823-4