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Select item 111314681.

Evolutionary and functional epitopes of the Spätzle protein: New insights into activation of the Toll receptor

Y. Wang, S. Zhu

Cell Mol Life Sci. 2009 May; 66(9): 1595–1602. Published online 2009 Mar 25. doi: 10.1007/s00018-009-9028-3

PMCID:: PMC11131468

Abstract Article PDF–2.3M

Select item 109730112.

The utility of Drosophila melanogaster as a fungal infection model

Chengetai D. Mpamhanga, Ilias Kounatidis

Front Immunol. 2024; 15: 1349027. Published online 2024 Mar 14. doi: 10.3389/fimmu.2024.1349027

PMCID:: PMC10973011

Abstract Article PDF–707K

Select item 109570853.

A single amino acid polymorphism in natural Metchnikowin alleles of Drosophila results in systemic immunity and life history tradeoffs

Jessamyn I. Perlmutter, Joanne R. Chapman, Mason C. Wilkinson, Isaac Nevarez-Saenz, Robert L. Unckless

PLoS Genet. 2024 Mar; 20(3): e1011155. Published online 2024 Mar 11. doi: 10.1371/journal.pgen.1011155

PMCID:: PMC10957085

Abstract Article PDF–1.7M

Select item 109359544.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 109177975.

A single-cell atlas of Drosophila trachea reveals glycosylation-mediated Notch signaling in cell fate specification

Yue Li, Tianfeng Lu, Pengzhen Dong, Jian Chen, Qiang Zhao, Yuying Wang, Tianheng Xiao, Honggang Wu, Quanyi Zhao, Hai Huang

Nat Commun. 2024; 15: 2019. Published online 2024 Mar 6. doi: 10.1038/s41467-024-46455-w

PMCID:: PMC10917797

Abstract Article PDF–5.3M

Select item 108256916.

Maintaining Toll signaling in Drosophila brain is required to sustain autophagy for dopamine neuron survival

Jie Zhang, Ting Tang, Ruonan Zhang, Liang Wen, Xiaojuan Deng, Xiaoxia Xu, Wanying Yang, Fengliang Jin, Yang Cao, Yuzhen Lu, Xiao-Qiang Yu

iScience. 2024 Feb 16; 27(2): 108795. Published online 2024 Jan 4. doi: 10.1016/j.isci.2024.108795

PMCID:: PMC10825691

Abstract Article PDF–6.2M

Select item 108162827.

The Lifespan of D. melanogaster Depends on the Function of the Gagr Gene, a Domesticated gag Gene of Drosophila LTR Retrotransposons

Yevgenia Balakireva, Maria Nikitina, Pavel Makhnovskii, Inna Kukushkina, Ilya Kuzmin, Alexander Kim, Lidia Nefedova

Insects. 2024 Jan; 15(1): 68. Published online 2024 Jan 17. doi: 10.3390/insects15010068

PMCID:: PMC10816282

Abstract Article PDF–4.1M

Select item 107737988.

Recent trends in insect gut immunity

Shahidul Ahmed Khan, Maryam Ali Mohmmadie Kojour, Yeon Soo Han

Front Immunol. 2023; 14: 1272143. Published online 2023 Dec 18. doi: 10.3389/fimmu.2023.1272143

PMCID:: PMC10773798

Abstract Article PDF–7.2M

Select item 107326909.

A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response

Jonathan B. Wang, Hsiao-Ling Lu, Huiyu Sheng, Raymond J St. Leger

Virulence. 2023; 14(1): 2275493. Published online 2023 Nov 8. doi: 10.1080/21505594.2023.2275493

PMCID:: PMC10732690

Abstract Article PDF–4.7M

Select item 1073253610.

An evolutionarily conserved serine protease network mediates melanization and Toll activation in Drosophila

Tisheng Shan, Yang Wang, Krishna Bhattarai, Haobo Jiang

Sci Adv. 2023 Dec 22; 9(51): eadk2756. Published online 2023 Dec 20. doi: 10.1126/sciadv.adk2756

PMCID:: PMC10732536

Abstract Article PDF–1.3M

Select item 1069306611.

Transcriptome analysis reveals temporally regulated genetic networks during Drosophila border cell collective migration

Emily Burghardt, Jessica Rakijas, Antariksh Tyagi, Pralay Majumder, Bradley J.S.C. Olson, Jocelyn A. McDonald

BMC Genomics. 2023; 24: 728. Published online 2023 Dec 1. doi: 10.1186/s12864-023-09839-8

PMCID:: PMC10693066

Abstract Article PDF–12M

Select item 1065109212.

A Drosophila model targets Eiger/TNFα to alleviate obesity-related insulin resistance and macrophage infiltration

Zhasmine Mirzoyan, Alice Valenza, Sheri Zola, Carola Bonfanti, Lorenzo Arnaboldi, Nicholas Ferrari, John Pollard, Valeria Lupi, Matteo Cassinelli, Matteo Frattaroli, Mehtap Sahin, Maria Enrica Pasini, Paola Bellosta

Dis Model Mech. 2023 Nov 1; 16(11): dmm050388. Published online 2023 Nov 6. doi: 10.1242/dmm.050388

PMCID:: PMC10651092

Abstract Article

Select item 1061700813.

Regulating metabolism to shape immune function: Lessons from Drosophila

Michelle L. Bland

Semin Cell Dev Biol. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Semin Cell Dev Biol. 2023 Mar 30; 138: 128–141. Published online 2022 Apr 16. doi: 10.1016/j.semcdb.2022.04.002

PMCID:: PMC10617008

Abstract Article PDF–954K

Select item 1060910714.

The Sterol Transporter Npc2c Controls Intestinal Stem Cell Mitosis and Host–Microbiome Interactions in Drosophila

Constantina Neophytou, Euripides Soteriou, Chrysoula Pitsouli

Metabolites. 2023 Oct; 13(10): 1084. Published online 2023 Oct 16. doi: 10.3390/metabo13101084

PMCID:: PMC10609107

Abstract Article PDF–8.3M

Select item 1059070715.

Drosophila Gut Immune Pathway Suppresses Host Development-Promoting Effects of Acetic Acid Bacteria

Jaegeun Lee, Xinge Song, Bom Hyun, Che Ok Jeon, Seogang Hyun

Mol Cells. 2023 Oct 31; 46(10): 637–653. Published online 2023 Sep 22. doi: 10.14348/molcells.2023.0141

PMCID:: PMC10590707

Abstract Article PDF–1.1M

Select item 1054606816.

Single-cell sequencing of tumor-associated macrophages in a Drosophila model

Dilan Khalili, Mubasher Mohammed, Martin Kunc, Martina Sindlerova, Johan Ankarklev, Ulrich Theopold

Front Immunol. 2023; 14: 1243797. Published online 2023 Sep 19. doi: 10.3389/fimmu.2023.1243797

PMCID:: PMC10546068

Abstract Article PDF–7.2M

Select item 1043400417.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 1027035118.

Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies

Shotaro Nakano, Soshiro Kashio, Kei Nishimura, Asuka Takeishi, Hina Kosakamoto, Fumiaki Obata, Erina Kuranaga, Takahiro Chihara, Yoshio Yamauchi, Toshiaki Isobe, Masayuki Miura

PLoS Genet. 2023 Jun; 19(6): e1010761. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010761