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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107988583.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001384.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106390615.

Yeast ribosome biogenesis factors Puf6 and Nog2 and ribosomal proteins uL2 and eL43 act in concert to facilitate the release of nascent large ribosomal subunits from the nucleolus

Amber J LaPeruta, Stefanie Hedayati, Jelena Micic, Fiona Fitzgerald, David Kim, Grace Oualline, John L Woolford

Nucleic Acids Res. 2023 Nov 10; 51(20): 11277–11290. Published online 2023 Oct 9. doi: 10.1093/nar/gkad794

PMCID:: PMC10639061

Abstract Article PDF–3.7M

Select item 102977006.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922107.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 95079698.

Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1

Michael Prattes, Irina Grishkovskaya, Victor-Valentin Hodirnau, Christina Hetzmannseder, Gertrude Zisser, Carolin Sailer, Vasileios Kargas, Mathias Loibl, Magdalena Gerhalter, Lisa Kofler, Alan J. Warren, Florian Stengel, David Haselbach, Helmut Bergler

Nat Struct Mol Biol. 2022; 29(9): 942–953. Published online 2022 Sep 12. doi: 10.1038/s41594-022-00832-5

PMCID:: PMC9507969

Abstract Article PDF–9.4M

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 899413510.

Emergence of the primordial pre-60S from the 90S pre-ribosome

Sherif Ismail, Dirk Flemming, Matthias Thoms, José Vicente Gomes-Filho, Lennart Randau, Roland Beckmann, Ed Hurt

Cell Rep. 2022 Apr 5; 39(1): 110640. Published online 2022 Apr 5. doi: 10.1016/j.celrep.2022.110640

PMCID:: PMC8994135

Abstract Article

Select item 857106311.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 819009512.

Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine

Michael Prattes, Irina Grishkovskaya, Victor-Valentin Hodirnau, Ingrid Rössler, Isabella Klein, Christina Hetzmannseder, Gertrude Zisser, Christian C. Gruber, Karl Gruber, David Haselbach, Helmut Bergler

Nat Commun. 2021; 12: 3483. Published online 2021 Jun 9. doi: 10.1038/s41467-021-23854-x

PMCID:: PMC8190095

Abstract Article PDF–3.2M

Select item 773068713.

Mutational Analysis of the Nsa2 N-Terminus Reveals Its Essential Role in Ribosomal 60S Subunit Assembly

Helge Paternoga, Alexander Früh, Ruth Kunze, Bettina Bradatsch, Jochen Baßler, Ed Hurt

Int J Mol Sci. 2020 Dec; 21(23): 9108. Published online 2020 Nov 30. doi: 10.3390/ijms21239108

PMCID:: PMC7730687

Abstract Article PDF–3.1M

Select item 771875114.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 675347115.

Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability

Eric E Bryant, Ivana Šunjevarić, Luke Berchowitz, Rodney Rothstein, Robert J D Reid

Nucleic Acids Res. 2019 Sep 26; 47(17): 9144–9159. Published online 2019 Jul 27. doi: 10.1093/nar/gkz631

PMCID:: PMC6753471

Abstract Article PDF–6.0M

Select item 661571016.

The nucleotide sequence of Saccharomyces cerevisiae chromosome XII

M. Johnston, L. Hillier, L. Riles, other members of the Genome Sequencing Center, K. Albermann, B. André, W. Ansorge, V. Benes, M. Brückner, H. Delius, E. Dubois, A. Düsterhöft, K.-D. Entian, M. Floeth, A. Goffeau, U. Hebling, K. Heumann, D. Heuss-Neitzel, H. Hilbert, F. Hilger, K. Kleine, P. Kötter, E. J. Louis, F. Messenguy, H. W. Mewes, T. Miosga, D. Möstl, S. Müller-Auer, U. Nentwich, B. Obermaier, E. Piravandi, T. M. Pohl, D. Portetelle, B. Purnelle, S. Rechmann, M. Rieger, M. Rinke, M. Rose, M. Scharfe, B. Scherens, P. Scholler, C. Schwager, S. Schwarz, A. P. Underwood, L. A. Urrestarazu, M. Vandenbol, P. Verhasselt, F. Vierendeels, M Voet, G. Volckaert, H. Voss, R. Wambutt, E. Wedler, H. Wedler, F. K. Zimmermann, A. Zollner, J. Hani, J. D. Hoheisel

Nature. Author manuscript; available in PMC 2019 Jul 9.

Published in final edited form as: Nature. 1997 May 29; 387(6632 Suppl): 87–90.

PMCID:: PMC6615710

Abstract Article PDF–424K

Select item 658956617.

Selective defects in gene expression control genome instability in yeast splicing mutants

Annie S. Tam, Tianna S. Sihota, Karissa L. Milbury, Anni Zhang, Veena Mathew, Peter C. Stirling

Mol Biol Cell. 2019 Jan 15; 30(2): 191–200. doi: 10.1091/mbc.E18-07-0439

PMCID:: PMC6589566

Abstract Article PDF–5.1M

Select item 657951818.

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes

Vasileios Kargas, Pablo Castro-Hartmann, Norberto Escudero-Urquijo, Kyle Dent, Christine Hilcenko, Carolin Sailer, Gertrude Zisser, Maria J Marques-Carvalho, Simone Pellegrino, Leszek Wawiórka, Stefan MV Freund, Jane L Wagstaff, Antonina Andreeva, Alexandre Faille, Edwin Chen, Florian Stengel, Helmut Bergler, Alan John Warren

eLife. 2019; 8: e44904. Published online 2019 May 22. doi: 10.7554/eLife.44904

PMCID:: PMC6579518

Abstract Article PDF–7.9M

Select item 647288019.

Saccharomyces cerevisiae Gle2/Rae1 is involved in septin organization, essential for cell cycle progression

Gesa Zander, Wilfried Kramer, Anika Seel, Heike Krebber

Yeast. 2017 Nov; 34(11): 459–470. Published online 2017 Sep 28. doi: 10.1002/yea.3249

PMCID:: PMC6472880

Abstract Article PDF–1.9M

Select item 592252820.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319

PMCID:: PMC5922528

Abstract Article PDF–7.1M

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