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Items: 1 to 20 of 46

1.
Jmjd2c maintains the ALDHbri+ cancer stemness with transcription factor SOX2 in lung squamous cell carcinoma
Min Wang, Yuling Hu, Feng Cai, Lili Guo, Yimin Mao, Yingmin Zhang
Cancer Biol Ther. 2024; 25(1): 2373447. Published online 2024 Jul 8. doi: 10.1080/15384047.2024.2373447
PMCID:
PMC11232651
AbstractArticlePDF–6.1M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The histone demethylase JMJD2C constitutes a novel NFE2 target gene that is required for the survival of JAK2V617F mutated cells
Anne Marie Staehle, Jan Caspar Peeken, Georg Vladimirov, Mirjam Elisabeth Hoeness, Sarolta Bojtine Kovacs, Nikolaos Karantzelis, Albert Gruender, Christoph Koellerer, Jonas Samuel Jutzi, Heike Luise Pahl, Hans Felix Staehle
Leukemia. 2023; 37(4): 919–923. Published online 2023 Jan 28. doi: 10.1038/s41375-023-01826-y
PMCID:
PMC10079541
AbstractArticlePDF–1.6M
4.
Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury
Heng-Chih Pan, Yau-Hung Chen, Wei-Ching Fang, Vin-Cent Wu, Chiao-Yin Sun
Int J Mol Sci. 2022 Aug; 23(16): 9318. Published online 2022 Aug 18. doi: 10.3390/ijms23169318
PMCID:
PMC9409075
AbstractArticlePDF–3.2M
5.
Targeting KDM4C enhances CD8+ T cell mediated antitumor immunity by activating chemokine CXCL10 transcription in lung cancer
Xiaohua Jie, Yunshang Chen, Ye Zhao, Xijie Yang, Yingzhuo Xu, Jian Wang, Rui Meng, Sheng Zhang, Xiaorong Dong, Tao Zhang, Kunyu Yang, Shuangbing Xu, Gang Wu
J Immunother Cancer. 2022; 10(2): e003716. Published online 2022 Feb 4. doi: 10.1136/jitc-2021-003716
PMCID:
PMC8819819
AbstractArticlePDF–4.8M
6.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance
Karl Agger, Koutarou Nishimura, Satoru Miyagi, Jan-Erik Messling, Kasper Dindler Rasmussen, Kristian Helin
Blood. 2019 Oct 3; 134(14): 1154–1158. Prepublished online 2019 Aug 21. doi: 10.1182/blood.2019000855
PMCID:
PMC6776794
AbstractArticle
10.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
11.
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland
Nature. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360
PMCID:
PMC6283663
AbstractArticlePDF–4.9M
12.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
13.
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
Yong Yu, Kolja Schleich, Bin Yue, Sujuan Ji, Philipp Lohneis, Kristel Kemper, Mark R. Silvis, Nouar Qutob, Ellen van Rooijen, Melanie Werner-Klein, Lianjie Li, Dhriti Dhawan, Svenja Meierjohann, Maurice Reimann, Abdel Elkahloun, Steffi Treitschke, Bernd Dörken, Christian Speck, Frédérick A. Mallette, Leonard I. Zon, Sheri L. Holmen, Daniel S. Peeper, Yardena Samuels, Clemens A. Schmitt, Soyoung Lee
Cancer Cell. Author manuscript; available in PMC 2018 May 31.
Published in final edited form as: Cancer Cell. 2018 Feb 12; 33(2): 322–336.e8. doi: 10.1016/j.ccell.2018.01.002
PMCID:
PMC5977991
AbstractArticlePDF–2.6M
14.
An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers
Cynthia L. Fisher, Hendrik Marks, Lily Ting-yin Cho, Robert Andrews, Sam Wormald, Thomas Carroll, Vivek Iyer, Peri Tate, Barry Rosen, Hendrik G. Stunnenberg, Amanda G. Fisher, William C. Skarnes
Nucleic Acids Res. 2017 Dec 1; 45(21): e174. Published online 2017 Sep 13. doi: 10.1093/nar/gkx811
PMCID:
PMC5716182
AbstractArticlePDF–3.8M
15.
Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin
Takumi Matsuura, Satsuki Miyazaki, Tatsushi Miyazaki, Fumi Tashiro, Jun-ichi Miyazaki
Sci Rep. 2017; 7: 12462. Published online 2017 Sep 29. doi: 10.1038/s41598-017-12772-y
PMCID:
PMC5622089
AbstractArticlePDF–8.7M
16.
Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation
Rute A. Tomaz, Jennifer L. Harman, Donja Karimlou, Lauren Weavers, Lauriane Fritsch, Tony Bou-Kheir, Emma Bell, Ignacio del Valle Torres, Kathy K. Niakan, Cynthia Fisher, Onkar Joshi, Hendrik G. Stunnenberg, Edward Curry, Slimane Ait-Si-Ali, Helle F. Jørgensen, Véronique Azuara
Development. 2017 Feb 15; 144(4): 567–579. doi: 10.1242/dev.142489
PMCID:
PMC5312034
AbstractArticle
17.
Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells
Karl Agger, Satoru Miyagi, Marianne Terndrup Pedersen, Susanne M. Kooistra, Jens Vilstrup Johansen, Kristian Helin
Genes Dev. 2016 Jun 1; 30(11): 1278–1288. doi: 10.1101/gad.280495.116
PMCID:
PMC4911927
AbstractArticlePDF–882K
18.
Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self‐renewal and early development
Marianne Terndrup Pedersen, Susanne Marije Kooistra, Aliaksandra Radzisheuskaya, Anne Laugesen, Jens Vilstrup Johansen, Daniel Geoffrey Hayward, Jakob Nilsson, Karl Agger, Kristian Helin
EMBO J. 2016 Jul 15; 35(14): 1550–1564. Published online 2016 Jun 6. doi: 10.15252/embj.201593317
PMCID:
PMC4899663
AbstractArticlePDF–2.1M
19.
Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse
K Fujiwara, Y Fujita, A Kasai, Y Onaka, H Hashimoto, H Okada, T Yamashita
Transl Psychiatry. 2016 Mar; 6(3): e766. Published online 2016 Mar 29. doi: 10.1038/tp.2016.31
PMCID:
PMC4872455
AbstractArticlePDF–1.1M
20.
Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia
Ngai Cheung, Tsz Kan Fung, Bernd B. Zeisig, Katie Holmes, Jayant K. Rane, Kerri A. Mowen, Michael G. Finn, Boris Lenhard, Li Chong Chan, Chi Wai Eric So
Cancer Cell. 2016 Jan 11; 29(1): 32–48. doi: 10.1016/j.ccell.2015.12.007
PMCID:
PMC4712026
AbstractArticle

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