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Items: 1 to 20 of 306

1.
A Cryptosporidium parvum vaccine candidate effect on immunohistochemical profiling of CD4+, CD8+, Caspase-3 and NF-κB in mice
Dina Aboelsoued, Nagwa I. Toaleb, Sally Ibrahim, Raafat M. Shaapan, Kadria N. Abdel Megeed
BMC Vet Res. 2023; 19: 216. Published online 2023 Oct 19. doi: 10.1186/s12917-023-03699-w
PMCID:
PMC10585919
AbstractArticlePDF–3.6M
2.
Widespread and dynamic expression of granzyme C by skin-resident antiviral T cells
Ramon A. Lujan, Luxin Pei, John P. Shannon, Nathânia Dábilla, Patrick T. Dolan, Heather D. Hickman
Front Immunol. 2023; 14: 1236595. Published online 2023 Sep 21. doi: 10.3389/fimmu.2023.1236595
PMCID:
PMC10552530
AbstractArticlePDF–8.4M
3.
CD8+ T cells maintain killing of MHC-I-negative tumor cells through the NKG2D–NKG2DL axis
Emily C. Lerner, Karolina I. Woroniecka, Vincent M. D’Anniballe, Daniel S. Wilkinson, Aditya A. Mohan, Selena J. Lorrey, Jessica Waibl-Polania, Lucas P. Wachsmuth, Alexandra M. Miggelbrink, Joshua D. Jackson, Xiuyu Cui, Jude A. Raj, William H. Tomaszewski, Sarah L. Cook, John H. Sampson, Anoop P. Patel, Mustafa Khasraw, Michael D. Gunn, Peter E. Fecci
Nat Cancer. 2023; 4(9): 1258–1272. Published online 2023 Aug 3. doi: 10.1038/s43018-023-00600-4
PMCID:
PMC10518253
AbstractArticlePDF–8.5M
4.
Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5
Norika Liu, Naofumi Kawahira, Yasuhiro Nakashima, Haruko Nakano, Akiyasu Iwase, Yasunobu Uchijima, Mei Wang, Sean M. Wu, Susumu Minamisawa, Hiroki Kurihara, Atsushi Nakano
Nat Commun. 2023; 14: 5398. Published online 2023 Sep 5. doi: 10.1038/s41467-023-41039-6
PMCID:
PMC10480477
AbstractArticlePDF–2.4M
5.
Glucose oxidation-dependent survival of activated B cells provides a putative novel therapeutic target for lupus treatment
John J. Wilson, Jian Wei, Andrea R. Daamen, John D. Sears, Elaine Bechtel, Colleen L. Mayberry, Grace A. Stafford, Lesley Bechtold, Amrie C. Grammer, Peter E. Lipsky, Derry C. Roopenian, Chih-Hao Chang
iScience. 2023 Sep 15; 26(9): 107487. Published online 2023 Jul 27. doi: 10.1016/j.isci.2023.107487
PMCID:
PMC10448027
AbstractArticlePDF–6.9M
6.
Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
Leyuan Ma, Alexander Hostetler, Duncan M. Morgan, Laura Maiorino, Ina Sulkaj, Charles A. Whittaker, Alexandra Neeser, Ivan Susin Pires, Parisa Yousefpour, Justin Gregory, Kashif Qureshi, Jonathan Dye, Wuhbet Abraham, Heikyung Suh, Na Li, J. Christopher Love, Darrell J. Irvine
Cell. Author manuscript; available in PMC 2023 Jul 27.
Published in final edited form as: Cell. 2023 Jul 20; 186(15): 3148–3165.e20. Published online 2023 Jul 5. doi: 10.1016/j.cell.2023.06.002
PMCID:
PMC10372881
AbstractArticlePDF–3.0M
7.
Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed oligodendrocytes in PLP1 mutant mice
Tassnim Abdelwahab, David Stadler, Konrad Knöpper, Panagiota Arampatzi, Antoine-Emmanuel Saliba, Wolfgang Kastenmüller, Rudolf Martini, Janos Groh
iScience. 2023 May 19; 26(5): 106698. Published online 2023 Apr 19. doi: 10.1016/j.isci.2023.106698
PMCID:
PMC10172788
AbstractArticlePDF–8.0M
8.
Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling
Dhwani N. Rupani, Fredrik I. Thege, Vidhi Chandra, Hajar Rajaei, Robert W. Cowan, Sonja M. Wörmann, Olivereen Le Roux, Prerna Malaney, Sara L. Manning, Jack Hashem, Jennifer Bailey-Lundberg, Andrew D. Rhim, Florencia McAllister
Development. 2023 Jan 15; 150(2): dev201097. Published online 2023 Jan 16. doi: 10.1242/dev.201097
PMCID:
PMC10110501
AbstractArticle
9.
Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade
Crismita Dmello, Junfei Zhao, Li Chen, Andrew Gould, Brandyn Castro, Victor A. Arrieta, Daniel Y. Zhang, Kwang-Soo Kim, Deepak Kanojia, Peng Zhang, Jason Miska, Ragini Yeeravalli, Karl Habashy, Ruth Saganty, Seong Jae Kang, Jawad Fares, Connor Liu, Gavin Dunn, Elizabeth Bartom, Matthew J. Schipma, Patrick D. Hsu, Mahmoud S. Alghamri, Maciej S. Lesniak, Amy B. Heimberger, Raul Rabadan, Catalina Lee-Chang, Adam M. Sonabend
Nat Commun. 2023; 14: 1566. Published online 2023 Mar 22. doi: 10.1038/s41467-023-36878-2
PMCID:
PMC10033639
AbstractArticlePDF–19M
10.
Low-Dose rIL-15 Protects from Nephrotoxic Serum Nephritis via CD8+ T Cells
Agnes A. Mooslechner, Max Schuller, Katharina Artinger, Alexander H. Kirsch, Corinna Schabhüttl, Philipp Eller, Alexander R. Rosenkranz, Kathrin Eller
Cells. 2022 Nov; 11(22): 3656. Published online 2022 Nov 18. doi: 10.3390/cells11223656
PMCID:
PMC9688325
AbstractArticlePDF–6.9M
11.
H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models
Santiago Haase, Kaushik Banerjee, Anzar A. Mujeeb, Carson S. Hartlage, Fernando M. Núñez, Felipe J. Núñez, Mahmoud S. Alghamri, Padma Kadiyala, Stephen Carney, Marcus N. Barissi, Ayman W. Taher, Emily K. Brumley, Sarah Thompson, Justin T. Dreyer, Caitlin T. Alindogan, Maria B. Garcia-Fabiani, Andrea Comba, Sriram Venneti, Visweswaran Ravikumar, Carl Koschmann, Ángel M. Carcaboso, Maria Vinci, Arvind Rao, Jennifer S. Yu, Pedro R. Lowenstein, Maria G. Castro
J Clin Invest. 2022 Nov 15; 132(22): e154229. Published online 2022 Nov 15. doi: 10.1172/JCI154229
PMCID:
PMC9663161
AbstractArticlePDF–4.0M
12.
CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
Tuğberk Kaya, Nicola Mattugini, Lu Liu, Hao Ji, Ludovico Cantuti-Castelvetri, Jianping Wu, Martina Schifferer, Janos Groh, Rudolf Martini, Simon Besson-Girard, Seiji Kaji, Arthur Liesz, Ozgun Gokce, Mikael Simons
Nat Neurosci. 2022; 25(11): 1446–1457. Published online 2022 Oct 24. doi: 10.1038/s41593-022-01183-6
PMCID:
PMC9630119
AbstractArticlePDF–22M
13.
Divergent outcomes of anti-PD-L1 treatment coupled with host-intrinsic differences in TCR repertoire and distinct T cell activation states in responding versus non-responding tumors
Jessy John, Rachel A. Woolaver, Vince Popolizio, Samantha M. Y. Chen, Huaibin Ge, Alexandra L. Krinsky, Monika Vashisht, Yonatan Kramer, Zhangguo Chen, Jing H. Wang
Front Immunol. 2022; 13: 992630. Published online 2022 Oct 18. doi: 10.3389/fimmu.2022.992630
PMCID:
PMC9624473
AbstractArticlePDF–21M
14.
Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma
Sruthi Ravindranathan, Tenzin Passang, Jian-Ming Li, Shuhua Wang, Rohan Dhamsania, Michael Brandon Ware, Mohammad Y. Zaidi, Jingru Zhu, Maria Cardenas, Yuan Liu, Sanjeev Gumber, Brian Robinson, Anish Sen-Majumdar, Hanwen Zhang, Shanmuganathan Chandrakasan, Haydn Kissick, Alan B. Frey, Susan N. Thomas, Bassel F. El-Rayes, Gregory B. Lesinski, Edmund K. Waller
Nat Commun. 2022; 13: 6418. Published online 2022 Oct 27. doi: 10.1038/s41467-022-34242-4
PMCID:
PMC9613684
AbstractArticlePDF–2.4M
15.
Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance
Ningbo Zheng, Jing Fang, Gang Xue, Ziyu Wang, Xiaoyin Li, Mengshi Zhou, Guangxu Jin, Masmudur M. Rahman, Grant McFadden, Yong Lu
Cancer Cell. Author manuscript; available in PMC 2023 Sep 12.
Published in final edited form as: Cancer Cell. 2022 Sep 12; 40(9): 973–985.e7. Published online 2022 Aug 25. doi: 10.1016/j.ccell.2022.08.001
PMCID:
PMC9489043
AbstractArticlePDF–3.1M
16.
Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling
Corina Anastasaki, Jit Chatterjee, Olivia Cobb, Shilpa Sanapala, Suzanne M. Scheaffer, Amanda De Andrade Costa, Anna F. Wilson, Chloe M. Kernan, Ameera H. Zafar, Xia Ge, Joel R. Garbow, Fausto J. Rodriguez, David H. Gutmann
Acta Neuropathol Commun. 2022; 10: 120. Published online 2022 Aug 19. doi: 10.1186/s40478-022-01428-2
PMCID:
PMC9392324
AbstractArticlePDF–13M
17.
T Cell activation and IFNγ modulate organ dysfunction in lipopolysaccharide-mediated inflammation
Matthew D. Taylor, Tiago D. Fernandes, Omar Yaipen, Cassidy E. Higgins, Christine A. Capone, Daniel E. Leisman, Ana Nedeljkovic-Kurepa, Mabel N. Abraham, Mariana R. Brewer, Clifford S. Deutschman
J Leukoc Biol. Author manuscript; available in PMC 2023 Aug 1.
Published in final edited form as: J Leukoc Biol. 2022 Aug; 112(2): 221–232. Published online 2022 Feb 9. doi: 10.1002/JLB.4HI0921-492R
PMCID:
PMC9351424
AbstractArticlePDF–2.5M
18.
BATF regulates progenitor to cytolytic effector CD8+ T cell transition during chronic viral infection
Yao Chen, Ryan A. Zander, Xiaopeng Wu, David M. Schauder, Moujtaba Y. Kasmani, Jian Shen, Shikan Zheng, Robert Burns, Elizabeth J. Taparowsky, Weiguo Cui
Nat Immunol. Author manuscript; available in PMC 2022 Jul 6.
Published in final edited form as: Nat Immunol. 2021 Aug; 22(8): 996–1007. Published online 2021 Jul 19. doi: 10.1038/s41590-021-00965-7
PMCID:
PMC9258987
AbstractArticlePDF–6.3M
19.
Reversal of the T cell immune system reveals the molecular basis for T cell lineage fate determination in the thymus
Miho Shinzawa, E. Ashley Moseman, Selamawit Gossa, Yasuko Mano, Abhisek Bhattacharya, Terry Guinter, Amala Alag, Xiongfong Chen, Maggie Cam, Dorian B. McGavern, Batu Erman, Alfred Singer
Nat Immunol. 2022; 23(5): 731–742. Published online 2022 Apr 29. doi: 10.1038/s41590-022-01187-1
PMCID:
PMC9098387
AbstractArticlePDF–13M
20.
Different syngeneic tumors show distinctive intrinsic tumor-immunity and mechanisms of actions (MOA) of anti-PD-1 treatment
Ying Jin, Xiaoyu An, Binchen Mao, Ruilin Sun, Rajendra Kumari, Xiaobo Chen, Yongli Shan, Mingfa Zang, Ling Xu, Jan Muntel, Kristina Beeler, Roland Bruderer, Lukas Reiter, Sheng Guo, Demin Zhou, Qi-Xiang Li, Xuesong Ouyang
Sci Rep. 2022; 12: 3278. Published online 2022 Feb 28. doi: 10.1038/s41598-022-07153-z
PMCID:
PMC8885837
AbstractArticlePDF–2.9M

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