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Select item 110309461.

Topoisomerase II alpha as a universal tumor antigen: antitumor immunity in murine tumor models and H-2K^b-restricted T cell epitope

Jung-Sun Park, Hye-Sung Kim, Mi-Young Park, Chang-Hyun Kim, Yeun-Jun Chung, Yong-Kil Hong, Tai-Gyu Kim

Cancer Immunol Immunother. 2010 May; 59(5): 747–757. Published online 2009 Nov 20. doi: 10.1007/s00262-009-0795-3

PMCID:: PMC11030946

Abstract Article PDF–567K

Select item 109366592.

TOP2A modulates signaling via the AKT/mTOR pathway to promote ovarian cancer cell proliferation

Kaiwen Zhang, Xingyu Zheng, Yiqing Sun, Xinyu Feng, Xirong Wu, Wenlu Liu, Chao Gao, Ye Yan, Wenyan Tian, Yingmei Wang

Cancer Biol Ther. 2024; 25(1): 2325126. Published online 2024 Mar 6. doi: 10.1080/15384047.2024.2325126

PMCID:: PMC10936659

Abstract Article PDF–7.9M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 101129644.

Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components

Gabriel Muciño-Hernández, Pilar Sarah Acevo-Rodríguez, Sandra Cabrera-Benitez, Adán Oswaldo Guerrero, Horacio Merchant-Larios, Susana Castro-Obregón

J Cell Sci. 2023 Jan 1; 136(1): jcs260563. Published online 2023 Jan 12. doi: 10.1242/jcs.260563

PMCID:: PMC10112964

Abstract Article

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 94584356.

Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37

Shangyao Qin, Yimin Yuan, Xiao Huang, Zijian Tan, Xin Hu, Hong Liu, Yingyan Pu, Yu-qiang Ding, Zhida Su, Cheng He

Nucleic Acids Res. 2022 Sep 9; 50(16): 9319–9338. Published online 2022 Aug 27. doi: 10.1093/nar/gkac731

PMCID:: PMC9458435

Abstract Article PDF–12M

Select item 90156997.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Abstract Article PDF–3.3M

Select item 87442578.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Abstract Article PDF–6.0M

Select item 86550339.

Single-cell analysis identifies a key role for Hhip in murine coronal suture development

Greg Holmes, Ana S. Gonzalez-Reiche, Madrikha Saturne, Susan M. Motch Perrine, Xianxiao Zhou, Ana C. Borges, Bhavana Shewale, Joan T. Richtsmeier, Bin Zhang, Harm van Bakel, Ethylin Wang Jabs

Nat Commun. 2021; 12: 7132. Published online 2021 Dec 8. doi: 10.1038/s41467-021-27402-5

PMCID:: PMC8655033

Abstract Article PDF–8.4M

Select item 863544610.

Heart neurons use clock genes to control myocyte proliferation

Emmanouil Tampakakis, Harshi Gangrade, Stephanie Glavaris, Myo Htet, Sean Murphy, Brian Leei Lin, Ting Liu, Amir Saberi, Matthew Miyamoto, William Kowalski, Yoh-Suke Mukouyama, Gabsang Lee, Liliana Minichiello, Chulan Kwon

Sci Adv. 2021 Dec; 7(49): eabh4181. Published online 2021 Dec 1. doi: 10.1126/sciadv.abh4181

PMCID:: PMC8635446

Abstract Article PDF–6.2M

Select item 831323911.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 828224112.

Single‐cell RNA‐Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation

Yuanlin He, Qiuzhen Chen, Juncheng Dai, Yiqiang Cui, Chi Zhang, Xidong Wen, Jiazhao Li, Yue Xiao, Xiaoxu Peng, Mingxi Liu, Bin Shen, Jiahao Sha, Zhibin Hu, Jing Li, Wenjie Shu

Aging Cell. 2021 Jul; 20(7): e13424. Published online 2021 Jun 26. doi: 10.1111/acel.13424

PMCID:: PMC8282241

Abstract Article PDF–3.6M

Select item 793877013.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 766956214.

Keratin 13 Deficiency Causes White Sponge Nevus in Mice

Laura Simonson, Samantha Vold, Colton Mowers, Randall J Massey, Irene M Ong, B. Jack Longley, Hao Chang

Dev Biol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Dev Biol. 2020 Dec 1; 468(1-2): 146–153. Published online 2020 Aug 3. doi: 10.1016/j.ydbio.2020.07.016

PMCID:: PMC7669562

Abstract Article PDF–2.2M

Select item 737917615.

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

Greg Holmes, Ana S. Gonzalez-Reiche, Na Lu, Xianxiao Zhou, Joshua Rivera, Divya Kriti, Robert Sebra, Anthony A. Williams, Michael J. Donovan, S. Steven Potter, Dalila Pinto, Bin Zhang, Harm van Bakel, Ethylin Wang Jabs

Cell Rep. Author manuscript; available in PMC 2020 Jul 24.

Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107871. doi: 10.1016/j.celrep.2020.107871

PMCID:: PMC7379176

Abstract Article PDF–3.0M

Select item 728652116.

Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes

Marco Gründl, Susanne Walz, Laura Hauf, Melissa Schwab, Kerstin Marcela Werner, Susanne Spahr, Clemens Schulte, Hans Michael Maric, Carsten P. Ade, Stefan Gaubatz

PLoS Genet. 2020 May; 16(5): e1008818. Published online 2020 May 29. doi: 10.1371/journal.pgen.1008818

PMCID:: PMC7286521

Abstract Article PDF–3.9M

Select item 722730517.

GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability

Gregoriy A. Dokshin, Gregory M. Davis, Ashley D. Sawle, Matthew D. Eldridge, Peter K. Nicholls, Taylin E. Gourley, Katherine A. Romer, Luke W. Molesworth, Hannah R. Tatnell, Ahmet R. Ozturk, Dirk G. de Rooij, Gregory J. Hannon, David C. Page, Craig C. Mello, Michelle A. Carmell

Dev Cell. Author manuscript; available in PMC 2021 Jan 6.

Published in final edited form as: Dev Cell. 2020 Jan 6; 52(1): 53–68.e6. Published online 2019 Dec 12. doi: 10.1016/j.devcel.2019.11.006

PMCID:: PMC7227305

Abstract Article PDF–1.3M

Select item 702167218.

Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency

Alejandro Álvarez-Quilón, José Terrón-Bautista, Irene Delgado-Sainz, Almudena Serrano-Benítez, Rocío Romero-Granados, Pedro Manuel Martínez-García, Silvia Jimeno-González, Cristina Bernal-Lozano, Cristina Quintero, Lourdes García-Quintanilla, Felipe Cortés-Ledesma

Nat Commun. 2020; 11: 910. Published online 2020 Feb 14. doi: 10.1038/s41467-020-14638-w

PMCID:: PMC7021672

Abstract Article PDF–5.5M

Select item 686837419.

ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation

Yan Rong, Shu-Yan Ji, Ye-Zhang Zhu, Yun-Wen Wu, Li Shen, Heng-Yu Fan

Nucleic Acids Res. 2019 Dec 2; 47(21): 11387–11402. Published online 2019 Oct 10. doi: 10.1093/nar/gkz863

PMCID:: PMC6868374

Abstract Article PDF–6.8M

Select item 672539420.

Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes

Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo

J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005

PMCID:: PMC6725394

Abstract Article PDF–682K

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