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Items: 1 to 20 of 247

1.
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice
Jeremy M. Sullivan, Anna M. Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C. Saavedra-Rivera, Lingling Kong, Jennifer S. Huh, Brett A. McCray, William H. Aisenberg, Aamir R. Zuberi, Laurent Bogdanik, Cathleen M. Lutz, Zhaozhu Qiu, Katharina A. Quinlan, Peter C. Searson, Charlotte J. Sumner
Sci Transl Med. Author manuscript; available in PMC 2024 Aug 10.
Published in final edited form as: Sci Transl Med. 2024 May 22; 16(748): eadk1358. Published online 2024 May 22. doi: 10.1126/scitranslmed.adk1358
PMCID:
PMC11316273
AbstractArticlePDF–2.3M
2.
Characterization of dUTPase expression in mouse postnatal development and adult neurogenesis
Nikolett Nagy, Nóra Hádinger, Otília Tóth, Gergely Attila Rácz, Tímea Pintér, Zoltán Gál, Martin Urbán, Elen Gócza, László Hiripi, László Acsády, Beáta G. Vértessy
Sci Rep. 2024; 14: 13139. Published online 2024 Jun 7. doi: 10.1038/s41598-024-63405-0
PMCID:
PMC11161619
AbstractArticlePDF–6.5M
3.
Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development
Eleonora Cesari, Donatella Farini, Vanessa Medici, Ingrid Ehrmann, Marika Guerra, Erika Testa, Chiara Naro, Maria Concetta Geloso, Vittoria Pagliarini, Livia La Barbera, Marcello D’Amelio, Tiziana Orsini, Stefano Farioli Vecchioli, Luca Tamagnone, Philippe Fort, Maria Teresa Viscomi, David J Elliott, Claudio Sette
Nucleic Acids Res. 2024 May 8; 52(8): 4167–4184. Published online 2024 Feb 7. doi: 10.1093/nar/gkae071
PMCID:
PMC11077083
AbstractArticlePDF–3.3M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension
Manasi Iyer, Husniye Kantarci, Madeline H. Cooper, Nicholas Ambiel, Sammy Weiser Novak, Leonardo R. Andrade, Mable Lam, Graham Jones, Alexandra E. Münch, Xinzhu Yu, Baljit S. Khakh, Uri Manor, J. Bradley Zuchero
Nat Commun. 2024; 15: 265. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44238-3
PMCID:
PMC10767123
AbstractArticlePDF–3.0M
6.
The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
Mathilde Pruvost, Julia Patzig, Camila Yattah, Ipek Selcen, Marylens Hernandez, Hye-Jin Park, Sarah Moyon, Shibo Liu, Malia S. Morioka, Lindsay Shopland, Osama Al-Dalahmah, Jaroslav Bendl, John F. Fullard, Panos Roussos, James Goldman, Ye He, Jeffrey L. Dupree, Patrizia Casaccia
Cell Rep. Author manuscript; available in PMC 2023 Oct 26.
Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112848. Published online 2023 Jul 28. doi: 10.1016/j.celrep.2023.112848
PMCID:
PMC10600948
AbstractArticlePDF–3.6M
7.
Autophagy collaborates with apoptosis pathways to control oligodendrocyte number
Tingxin Zhang, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Han-Gyu Bae, Jumin Xue, Sabeen Wazir, Sara B. Mulinyawe, Jun Hee Kim, Lu O. Sun
Cell Rep. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112943. Published online 2023 Aug 6. doi: 10.1016/j.celrep.2023.112943
PMCID:
PMC10529879
AbstractArticlePDF–3.5M
8.
Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon
Mary Jo Talley, Diana Nardini, Lisa A. Ehrman, Q. Richard Lu, Ronald R. Waclaw
Neural Dev. 2023; 18: 5. Published online 2023 Sep 8. doi: 10.1186/s13064-023-00173-z
PMCID:
PMC10485956
AbstractArticlePDF–15M
9.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
10.
PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development
Vanessa Waldhauser, Tina Baroti, Franziska Fröb, Michael Wegner
Cells. 2023 Jun; 12(12): 1556. Published online 2023 Jun 6. doi: 10.3390/cells12121556
PMCID:
PMC10296403
AbstractArticlePDF–20M
11.
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
Constanze Depp, Ting Sun, Andrew Octavian Sasmita, Lena Spieth, Stefan A. Berghoff, Taisiia Nazarenko, Katharina Overhoff, Agnes A. Steixner-Kumar, Swati Subramanian, Sahab Arinrad, Torben Ruhwedel, Wiebke Möbius, Sandra Göbbels, Gesine Saher, Hauke B. Werner, Alkmini Damkou, Silvia Zampar, Oliver Wirths, Maik Thalmann, Mikael Simons, Takashi Saito, Takaomi Saido, Dilja Krueger-Burg, Riki Kawaguchi, Michael Willem, Christian Haass, Daniel Geschwind, Hannelore Ehrenreich, Ruth Stassart, Klaus-Armin Nave
Nature. 2023; 618(7964): 349–357. Published online 2023 May 31. doi: 10.1038/s41586-023-06120-6
PMCID:
PMC10247380
AbstractArticlePDF–19M
12.
Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development
Samu N Kurki, Pavel Uvarov, Alexey S Pospelov, Kalevi Trontti, Antje K Hübner, Rakenduvadhana Srinivasan, Masahiko Watanabe, Iiris Hovatta, Christian A Hübner, Kai Kaila, Mari A Virtanen
Cereb Cortex. 2023 May 15; 33(10): 5906–5923. Published online 2022 Dec 27. doi: 10.1093/cercor/bhac470
PMCID:
PMC10183754
AbstractArticlePDF–3.1M
13.
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination
Hannah Kapell, Luca Fazio, Julia Dyckow, Sophia Schwarz, Andrés Cruz-Herranz, Christina Mayer, Joaquin Campos, Elisa D’Este, Wiebke Möbius, Christian Cordano, Anne-Katrin Pröbstel, Marjan Gharagozloo, Amel Zulji, Venu Narayanan Naik, Anna Delank, Manuela Cerina, Thomas Müntefering, Celia Lerma-Martin, Jana K. Sonner, Jung Hyung Sin, Paul Disse, Nicole Rychlik, Khalida Sabeur, Manideep Chavali, Rajneesh Srivastava, Matthias Heidenreich, Kathryn C. Fitzgerald, Guiscard Seebohm, Christine Stadelmann, Bernhard Hemmer, Michael Platten, Thomas J. Jentsch, Maren Engelhardt, Thomas Budde, Klaus-Armin Nave, Peter A. Calabresi, Manuel A. Friese, Ari J. Green, Claudio Acuna, David H. Rowitch, Sven G. Meuth, Lucas Schirmer
J Clin Invest. 2023 Apr 3; 133(7): e164223. Published online 2023 Apr 3. doi: 10.1172/JCI164223
PMCID:
PMC10065072
AbstractArticlePDF–3.9M
14.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
15.
Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death
Etan R. Aber, Christopher J. Griffey, Tim Davies, Alice M. Li, Young Joo Yang, Katherine R. Croce, James E. Goldman, Jaime Grutzendler, Julie C. Canman, Ai Yamamoto
Cell Rep. Author manuscript; available in PMC 2022 Nov 7.
Published in final edited form as: Cell Rep. 2022 Oct 18; 41(3): 111480. doi: 10.1016/j.celrep.2022.111480
PMCID:
PMC9639605
AbstractArticlePDF–4.9M
16.
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex
Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner
Nat Commun. 2022; 13: 4209. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31752-z
PMCID:
PMC9304408
AbstractArticlePDF–13M
17.
Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression
Norihisa Bizen, Asim K. Bepari, Li Zhou, Manabu Abe, Kenji Sakimura, Katsuhiko Ono, Hirohide Takebayashi
Cell Death Differ. 2022 May; 29(5): 1028–1041. Published online 2022 Jan 1. doi: 10.1038/s41418-021-00915-8
PMCID:
PMC9090832
AbstractArticlePDF–8.5M
18.
Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism
Aiman S. Saab, Iva D. Tzvetavona, Andrea Trevisiol, Selva Baltan, Payam Dibaj, Kathrin Kusch, Wiebke Möbius, Bianka Goetze, Hannah M. Jahn, Wenhui Huang, Heinz Steffens, Eike D. Schomburg, Alberto Pérez-Samartín, Fernando Pérez-Cerdá, Davood Bakhtiari, Carlos Matute, Siegrid Löwel, Christian Griesinger, Johannes Hirrlinger, Frank Kirchhoff, Klaus-Armin Nave
Neuron. Author manuscript; available in PMC 2022 May 9.
Published in final edited form as: Neuron. 2016 Jul 6; 91(1): 119–132. Published online 2016 Jun 9. doi: 10.1016/j.neuron.2016.05.016
PMCID:
PMC9084537
AbstractArticlePDF–2.3M
19.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
20.
ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve
Hye-Jin Park, Eric Tsai, Dennis Huang, Michael Weaver, Luciana Frick, Ace Alcantara, John J. Moran, Julia Patzig, Carmen V. Melendez-Vasquez, Gerald R. Crabtree, M.L. Feltri, John Svaren, Patrizia Casaccia
iScience. 2022 Apr 15; 25(4): 104132. Published online 2022 Mar 23. doi: 10.1016/j.isci.2022.104132
PMCID:
PMC9010646
AbstractArticlePDF–5.7M

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