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Select item 114419841.

Mesenchymal Osr1⁺ cells regulate embryonic lymphatic vessel formation

Pedro Vallecillo-García, Mira Nicola Kühnlein, Mickael Orgeur, Nils Rouven Hansmeier, Georgios Kotsaris, Zarah Gertrud Meisen, Bernd Timmermann, Claudia Giesecke-Thiel, René Hägerling, Sigmar Stricker

Development. 2024 Sep 1; 151(17): dev202747. Published online 2024 Sep 2. doi: 10.1242/dev.202747

PMCID:: PMC11441984

Abstract Article

Select item 114113392.

In vitro differentiation of mouse pluripotent stem cells into corticosteroid-producing adrenocortical cells

Ioannis Oikonomakos, Melina Tedesco, Fariba Jian Motamedi, Mirko Peitzsch, Serge Nef, Stefan R. Bornstein, Andreas Schedl, Charlotte Steenblock, Yasmine Neirijnck

Stem Cell Reports. 2024 Sep 10; 19(9): 1289–1303. Published online 2024 Aug 22. doi: 10.1016/j.stemcr.2024.07.010

PMCID:: PMC11411339

Abstract Article PDF–5.7M

Select item 112161733.

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development

James F. Clark, Philippe Soriano

Genes Dev. 2024 May 1; 38(9-10): 393–414. doi: 10.1101/gad.351593.124

PMCID:: PMC11216173

Abstract Article PDF–17M

Select item 106889844.

OSR1 disruption contributes to uterine factor infertility via impaired Müllerian duct development and endometrial receptivity

Adriana Lofrano-Porto, Sidney Alcântara Pereira, Andrew Dauber, Jordana C.B. Bloom, Audrey N. Fontes, Naomi Asimow, Olívia Laquis de Moraes, Petra Ariadne T. Araujo, Ana Paula Abreu, Michael H. Guo, Silviene F. De Oliveira, Han Liu, Charles Lee, Wendy Kuohung, Michella S. Coelho, Rona S. Carroll, Rulang Jiang, Ursula B. Kaiser

J Clin Invest. 2023 Dec 1; 133(23): e161701. Published online 2023 Dec 1. doi: 10.1172/JCI161701

PMCID:: PMC10688984

Abstract Article PDF–31M

Select item 105063975.

Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages

Megan Rowton, Carlos Perez-Cervantes, Suzy Hur, Jessica Jacobs-Li, Emery Lu, Nikita Deng, Alexander Guzzetta, Andrew D. Hoffmann, Matthew Stocker, Jeffrey D. Steimle, Sonja Lazarevic, Sophie Oubaha, Xinan H. Yang, Chul Kim, Shuhan Yu, Heather Eckart, Mervenaz Koska, Erika Hanson, Sunny S.K. Chan, Daniel J. Garry, Michael Kyba, Anindita Basu, Kohta Ikegami, Sebastian Pott, Ivan P. Moskowitz

Dev Cell. Author manuscript; available in PMC 2023 Sep 18.

Published in final edited form as: Dev Cell. 2022 Sep 26; 57(18): 2181–2203.e9. Published online 2022 Sep 14. doi: 10.1016/j.devcel.2022.08.009

PMCID:: PMC10506397

Abstract Article PDF–3.7M

Select item 104787546.

CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression

Athanasia Stathopoulou, Ping Wang, Charlotte Thellier, Robert G Kelly, Deyou Zheng, Peter J Scambler

Cardiovasc Res. 2023 Aug; 119(11): 2089–2105. Published online 2023 Apr 13. doi: 10.1093/cvr/cvad059

Correction in:: Cardiovasc Res. 2024 Jan; 120(1): 120.

PMCID:: PMC10478754

Abstract Article PDF–21M

Select item 100367397.

Osr1 Regulates Macrophage-mediated Liver Inflammation in Nonalcoholic Fatty Liver Disease Progression

Lin Liu, Yi Zhou, Zhimin Liu, Jiangyuan Li, Linghao Hu, Leya He, Guannan Gao, Brian Kidd, Alexandra Walsh, Rulang Jiang, Chaodong Wu, Ke Zhang, Linglin Xie

Cell Mol Gastroenterol Hepatol. 2023; 15(5): 1117–1133. Published online 2022 Dec 27. doi: 10.1016/j.jcmgh.2022.12.010

PMCID:: PMC10036739

Abstract Article PDF–11M

Select item 99826678.

Biallelic variants in ADAMTS15 cause a novel form of distal arthrogryposis

Felix Boschann, Muhsin Ö. Cogulu, Davut Pehlivan, Saranya Balachandran, Pedro Vallecillo-Garcia, Christopher M. Grochowski, Nils R. Hansmeier, Zeynep H. Coban Akdemir, Cesar A. Prada-Medina, Ayca Aykut, Björn Fischer-Zirnsak, Simon Badura, Burak Durmaz, Ferda Ozkinay, René Hägerling, Jennifer E. Posey, Sigmar Stricker, Gabriele Gillessen-Kaesbach, Malte Spielmann, Denise Horn, Knut Brockmann, James R. Lupski, Uwe Kornak, Julia Schmidt

Genet Med. Author manuscript; available in PMC 2023 Oct 1.

Published in final edited form as: Genet Med. 2022 Oct; 24(10): 2187–2193. Published online 2022 Aug 13. doi: 10.1016/j.gim.2022.07.012

Correction in:: Genet Med. 2023 Feb 28 : 100799.

PMCID:: PMC9982667

Abstract Article PDF–435K

Select item 93343539.

Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes

Won Kyung Kim, Adam W. Olson, Jiaqi Mi, Jinhui Wang, Dong-Hoon Lee, Vien Le, Alex Hiroto, Joseph Aldahl, Christian H. Nenninger, Alyssa J. Buckley, Robert Cardiff, Sungyong You, Zijie Sun

Nat Commun. 2022; 13: 4364. Published online 2022 Jul 28. doi: 10.1038/s41467-022-32119-0

PMCID:: PMC9334353

Abstract Article PDF–13M

Select item 916580310.

Disrupting Osr1 expression promoted hepatic steatosis and inflammation induced by high-fat diet in the mouse model

Ernest C. Lynch, Zhimin Liu, Lin Liu, Xian Wang, Ke K. Zhang, Linglin Xie

PLoS One. 2022; 17(6): e0268344. Published online 2022 Jun 3. doi: 10.1371/journal.pone.0268344

PMCID:: PMC9165803

Abstract Article PDF–2.2M

Select item 880759511.

Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma

Shunsuke Tanigawa, Etsuko Tanaka, Koichiro Miike, Tomoko Ohmori, Daisuke Inoue, Chen-Leng Cai, Atsuhiro Taguchi, Akio Kobayashi, Ryuichi Nishinakamura

Nat Commun. 2022; 13: 611. Published online 2022 Feb 1. doi: 10.1038/s41467-022-28226-7

Correction in:: Nat Commun. 2023; 14: 1874.

PMCID:: PMC8807595

Abstract Article PDF–5.4M

Select item 861916312.

Osr1 Is Required for Mesenchymal Derivatives That Produce Collagen in the Bladder

Vasikar Murugapoopathy, Philippe G. Cammisotto, Abubakr H. Mossa, Lysanne Campeau, Indra R. Gupta

Int J Mol Sci. 2021 Nov; 22(22): 12387. Published online 2021 Nov 17. doi: 10.3390/ijms222212387

PMCID:: PMC8619163

Abstract Article PDF–5.8M

Select item 858141613.

hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9

Yujiao Wen, Xixiang Ma, Xiaoli Wang, Fengli Wang, Juan Dong, Yanqing Wu, Chunyu Lv, Kuan Liu, Yan Zhang, Zhibing Zhang, Shuiqiao Yuan

Theranostics. 2021; 11(20): 10030–10046. Published online 2021 Oct 25. doi: 10.7150/thno.66819

PMCID:: PMC8581416

Abstract Article PDF–3.5M

Select item 856650214.

Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice

Eriko Nakamura, Kenji Hata, Yoshifumi Takahata, Hiroshi Kurosaka, Makoto Abe, Takaya Abe, Miho Kihara, Toshihisa Komori, Sachi Kobayashi, Tomohiko Murakami, Toshihiro Inubushi, Takashi Yamashiro, Shiori Yamamoto, Haruhiko Akiyama, Makoto Kawaguchi, Nobuo Sakata, Riko Nishimura

Commun Biol. 2021; 4: 1258. Published online 2021 Nov 3. doi: 10.1038/s42003-021-02793-9

PMCID:: PMC8566502

Abstract Article PDF–1.9M

Select item 798787115.

Osr1 regulates hepatic inflammation and cell survival in the progression of non-alcoholic fatty liver disease

Yi Zhou, Zhimin Liu, Ernest C. Lynch, Leya He, Henghui Cheng, Lin Liu, Zhen Li, Jiangyuan Li, Lauren Lawless, Ke K. Zhang, Linglin Xie

Lab Invest. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Lab Invest. 2021 Apr; 101(4): 477–489. Published online 2020 Oct 1. doi: 10.1038/s41374-020-00493-2

PMCID:: PMC7987871

Abstract Article PDF–3.2M

Select item 746261716.

Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation

Sonia Stefanovic, Brigitte Laforest, Jean-Pierre Desvignes, Fabienne Lescroart, Laurent Argiro, Corinne Maurel-Zaffran, David Salgado, Elise Plaindoux, Christopher De Bono, Kristijan Pazur, Magali Théveniau-Ruissy, Christophe Béroud, Michel Puceat, Anthony Gavalas, Robert G Kelly, Stephane Zaffran

eLife. 2020; 9: e55124. Published online 2020 Aug 17. doi: 10.7554/eLife.55124

PMCID:: PMC7462617

Abstract Article PDF–12M

Select item 745302717.

Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis

Lu Han, Praneet Chaturvedi, Keishi Kishimoto, Hiroyuki Koike, Talia Nasr, Kentaro Iwasawa, Kirsten Giesbrecht, Phillip C. Witcher, Alexandra Eicher, Lauren Haines, Yarim Lee, John M. Shannon, Mitsuru Morimoto, James M. Wells, Takanori Takebe, Aaron M. Zorn

Nat Commun. 2020; 11: 4158. Published online 2020 Aug 27. doi: 10.1038/s41467-020-17968-x

PMCID:: PMC7453027

Abstract Article PDF–6.5M

Select item 739063918.

A single cell transcriptional atlas of early synovial joint development

Qin Bian, Yu-Hao Cheng, Jordan P. Wilson, Emily Y. Su, Dong Won Kim, Hong Wang, Sooyeon Yoo, Seth Blackshaw, Patrick Cahan

Development. 2020 Jul 15; 147(14): dev185777. Published online 2020 Jul 20. doi: 10.1242/dev.185777

PMCID:: PMC7390639

Abstract Article

Select item 717051819.

The transcriptional regulator MEIS2 sets up the ground state for palatal osteogenesis in mice

Linyan Wang, Qinghuang Tang, Jue Xu, Hua Li, Tianfang Yang, Liwen Li, Ondrej Machon, Tao Hu, YiPing Chen

J Biol Chem. 2020 Apr 17; 295(16): 5449–5460. Published online 2020 Mar 13. doi: 10.1074/jbc.RA120.012684

PMCID:: PMC7170518

Abstract Article PDF–6.6M

Select item 698582420.

WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia

Martin N. Thomson, Catherina A. Cuevas, Tim M. Bewarder, Carsten Dittmayer, Lauren N. Miller, Jinge Si, Ryan J. Cornelius, Xiao-Tong Su, Chao-Ling Yang, James A. McCormick, Juliette Hadchouel, David H. Ellison, Sebastian Bachmann, Kerim Mutig

Am J Physiol Renal Physiol. 2020 Jan 1; 318(1): F216–F228. Published online 2019 Nov 18. doi: 10.1152/ajprenal.00232.2019

PMCID:: PMC6985824

Abstract Article

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