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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 95748792.

UCP3 is associated with Hax-1 in mitochondria in the presence of calcium ion

Katsuya Hirasaka, Edward M. Mills, Marie Haruna, Aki Bando, Chika Ikeda, Tomoki Abe, Shohei Kohno, Sara M. Nowinski, Cory U. Lago, Ken-ichi Akagi, Hidehito Tochio, Ayako Ohno, Shigetada Teshima-Kondo, Yuushi Okumura, Takeshi Nikawa

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 17.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Mar 25; 472(1): 108–113. Published online 2016 Feb 23. doi: 10.1016/j.bbrc.2016.02.075

PMCID:: PMC9574879

Abstract Article PDF–987K

Select item 92396843.

Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model

Mariah L Hoye, Lorenzo Calviello, Abigail J Poff, Nna-Emeka Ejimogu, Carly R Newman, Maya D Montgomery, Jianhong Ou, Stephen N Floor, Debra L Silver

eLife. 2022; 11: e78203. Published online 2022 Jun 28. doi: 10.7554/eLife.78203

PMCID:: PMC9239684

Abstract Article PDF–14M

Select item 89799854.

Anti-apoptotic HAX-1 suppresses cell apoptosis by promoting c-Abl kinase-involved ROS clearance

Qincai Dong, Dapei Li, Huailong Zhao, Xun Zhang, Yue Liu, Yong Hu, Yi Yao, Lin Zhu, Guang-Fei Wang, Hainan Liu, Ting Gao, Xiayang Niu, Tong Zheng, Caiwei Song, Di Wang, Yu Bai, Jing Jin, Zijing Liu, Yanwen Jin, Ping Li, Cheng Cao, Xuan Liu

Cell Death Dis. 2022 Apr; 13(4): 298. Published online 2022 Apr 4. doi: 10.1038/s41419-022-04748-2

PMCID:: PMC8979985

Abstract Article PDF–6.4M

Select item 79799255.

Cerebellar Kv3.3 potassium channels activate TANK-binding kinase 1 to regulate trafficking of the cell survival protein Hax-1

Yalan Zhang, Luis Varela, Klara Szigeti-Buck, Adam Williams, Milan Stoiljkovic, Matija Šestan-Peša, Jorge Henao-Mejia, Pasquale D’Acunzo, Efrat Levy, Richard A. Flavell, Tamas L. Horvath, Leonard K. Kaczmarek

Nat Commun. 2021; 12: 1731. Published online 2021 Mar 19. doi: 10.1038/s41467-021-22003-8

PMCID:: PMC7979925

Abstract Article PDF–5.9M

Select item 71359886.

Hepatic HAX-1 inactivation prevents metabolic diseases by enhancing mitochondrial activity and bile salt export

Fawzi Alogaili, Sivaprakasam Chinnarasu, Anja Jaeschke, Evangelia G. Kranias, David Y. Hui

J Biol Chem. 2020 Apr 3; 295(14): 4631–4646. Published online 2020 Feb 20. doi: 10.1074/jbc.RA119.012361

PMCID:: PMC7135988

Abstract Article PDF–6.7M

Select item 70170027.

TCTP is Essential for Cell Proliferation and Survival during CNS Development

Sung-Ho Chen, Chin-Hung Lu, Ming-Jen Tsai

Cells. 2020 Jan; 9(1): 133. Published online 2020 Jan 6. doi: 10.3390/cells9010133

PMCID:: PMC7017002

Abstract Article PDF–6.4M

Select item 66023008.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 58011689.

HAX-1 Regulates SERCA2a Oxidation and Degradation

Philip A. Bidwell, Guan-Sheng Liu, Narayani Nagarajan, Chi Keung Lam, Kobra Haghighi, George Gardner, Wen-Feng Cai, Wen Zhao, Luke Mugge, Elizabeth Vafiadaki, Despina Sanoudou, Jack Rubinstein, Djamel Lebeche, Roger Hajjar, Junichi Sadoshima, Evangelia G. Kranias

J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: J Mol Cell Cardiol. 2018 Jan; 114: 220–233. Published online 2017 Nov 21. doi: 10.1016/j.yjmcc.2017.11.014

PMCID:: PMC5801168

Abstract Article PDF–1.1M

Select item 576691710.

The antiapoptotic protein HAX-1 mediates half of phospholamban's inhibitory activity on calcium cycling and contractility in the heart

Philip A. Bidwell, Kobra Haghighi, Evangelia G. Kranias

J Biol Chem. 2018 Jan 5; 293(1): 359–367. Published online 2017 Nov 17. doi: 10.1074/jbc.RA117.000128

PMCID:: PMC5766917

Abstract Article PDF–1.3M

Select item 538122611.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 494781312.

HAX1 deletion impairs BCR internalization and leads to delayed BCR-mediated apoptosis

Susanne Wolkerstorfer, Elisabeth Schwaiger, Mark Rinnerthaler, Iris Karina Gratz, Thomas Zoegg, Hans Brandstetter, Gertrude Achatz-Straussberger

Cell Mol Immunol. 2016 Jul; 13(4): 451–461. Published online 2015 Apr 13. doi: 10.1038/cmi.2015.18

PMCID:: PMC4947813

Abstract Article PDF–1.2M

Select item 482629613.

Kv3.3 channels bind Hax-1 and Arp2/3 to assemble a stable local actin network that regulates channel gating

Yalan Zhang, Xiao-Feng Zhang, Matthew R. Fleming, Anahita Amiri, Lynda El-Hassar, Alexei A. Surguchev, Callen Hyland, David P. Jenkins, Rooma Desai, Maile R. Brown, Valeswara-Rao Gazula, Michael F. Waters, Charles H. Large, Tamas L. Horvath, Dhasakumar Navaratnam, Flora M. Vaccarino, Paul Forscher, Leonard K. Kaczmarek

Cell. Author manuscript; available in PMC 2017 Apr 7.

Published in final edited form as: Cell. 2016 Apr 7; 165(2): 434–448. Published online 2016 Mar 17. doi: 10.1016/j.cell.2016.02.009

PMCID:: PMC4826296

Abstract Article PDF–1.8M

Select item 469220714.

Regulation of Focal Adhesion Dynamics and Cell Motility by the EB2 and Hax1 Protein Complex

Han Liu, Jiping Yue, He Huang, Xuewen Gou, Shao-Yu Chen, Yingming Zhao, Xiaoyang Wu

J Biol Chem. 2015 Dec 25; 290(52): 30771–30782. Published online 2015 Nov 2. doi: 10.1074/jbc.M115.671743

Correction in:: J Biol Chem. 2019 Feb 22; 294(8): 2948.

PMCID:: PMC4692207

Abstract Article PDF–4.1M

Select item 466435315.

HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart

Chi Keung Lam, Wen Zhao, Guan-Sheng Liu, Wen-Feng Cai, George Gardner, George Adly, Evangelia G. Kranias

Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47): E6466–E6475. Published online 2015 Nov 9. doi: 10.1073/pnas.1508760112

PMCID:: PMC4664353

Abstract Article PDF–1.6M

Select item 456196916.

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice

Jia-yuan Wu, Mei Li, Li-juan Cao, Mei-ling Sun, Dong Chen, Hai-gang Ren, Qin Xia, Zhou-teng Tao, Zheng-hong Qin, Qing-song Hu, Guang-hui Wang

Acta Pharmacol Sin. 2015 Sep; 36(9): 1043–1052. Published online 2015 Aug 24. doi: 10.1038/aps.2015.50

PMCID:: PMC4561969

Abstract Article PDF–3.2M

Select item 430085217.

Hax1 is not a Bcl-2-family-related protein and does not present Omi/HtrA2 to PARL : implications for mitochondrial stress and apoptosis

Danny V. Jeyaraju, Giulia Cisbani, Olga M. De Brito, Eugene V. Koonin, Luca Pellegrini

Cell Death Differ. Author manuscript; available in PMC 2015 Jan 21.

Published in final edited form as: Cell Death Differ. 2009 Dec; 16(12): 1622–1629. Published online 2009 Aug 14. doi: 10.1038/cdd.2009.110

PMCID:: PMC4300852

Abstract Article PDF–1.3M

Select item 353790218.

Novel Role of HAX-1 in Ischemic Injury Protection: Involvement of Hsp90

Chi Keung Lam, Wen Zhao, Wenfeng Cai, Elizabeth Vafiadaki, Stela M. Florea, Xiaoping Ren, Yong Liu, Nathan Robbins, Zhiguo Zhang, Xiaoyang Zhou, Jiang Min, Jack Rubinstein, W. Keith Jones, Evangelia G. Kranias

Circ Res. Author manuscript; available in PMC 2014 Jan 4.

Published in final edited form as: Circ Res. 2013 Jan 4; 112(1): 79–89. Published online 2012 Sep 14. doi: 10.1161/CIRCRESAHA.112.279935

PMCID:: PMC3537902

Abstract Article PDF–4.1M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 279160320.

The anti-apoptotic protein HAX-1 is a regulator of cardiac function

Wen Zhao, Jason R. Waggoner, Zhi-Guo Zhang, Chi Keung Lam, Peidong Han, Jiang Qian, Paul M. Schroder, Bryan Mitton, Aikaterini Kontrogianni-Konstantopoulos, Seth L. Robia, Evangelia G. Kranias

Proc Natl Acad Sci U S A. 2009 Dec 8; 106(49): 20776–20781. Published online 2009 Nov 17. doi: 10.1073/pnas.0906998106

PMCID:: PMC2791603

Abstract Article PDF–1.2M

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